Irish Child Health Database - Peer Reviewed Papers
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Infant, Newborn
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This article discusses post maternity rights
Geography:
Republic of Ireland
World of Irish Nursing,
Vol: 10 Page: 22-22 2002
P. McGinn
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This study describes features associated with the presentation of posterior fossa tumours in childhood
Abstract:
A retrospective review was performed of the age profile and clinical features at presentation of 79 children with posterior fossa tumours. The mean age at presentation in this series (6.6 years) is consistent with a decreasing trend over the past 70 years. Headaches, ataxia and torticollis emerge as significant symptoms worthy of further investigation whilst abdominal pain and more...
International Classification:
Neoplasms - Malignant neoplasms - posterior fossa tumours
Categories:
posterior fossa tumours
Geography:
Republic of Ireland
Ir Med J,
Vol: 94 Page: 52-3 February 2001
D. F. O'Brien; J. Caird; M. Kennedy; G. A. Roberts; J. C. Marks; D. A. Allcutt
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This paper discusses postnatal corticosteroids given early after birth reduce the risk of chronic lung disease in preterm infants but are associated with an approximate doubling of the risk of adverse neurosensory outcomes
Abstract:
Postnatal corticosteroids given early after birth reduce the risk of chronic lung disease in preterm infants but are associated with an approximate doubling of the risk of adverse neurosensory outcomes. Corticosteroids given after 7-10 d of age appear not to have these increased risks of neurosensory sequelae and reduce time on the ventilator. CONCLUSION: Further research is needed to more...
Geography:
Northern Ireland
Acta Paediatr,
Vol: 92 Page: 888-9 August 2003
H. L. Halliday
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This article discusse systematic reviews of randomised controlled trials of postnatal steroids (either systemic or inhaled) for CLD in the Cochrane Library were evaluated as a guide to clinical practice
Abstract:
INTRODUCTION: Chronic lung disease (CLD) represents a condition of persistent inflammation within the airways which may have its origin either in utero or after birth. Corticosteroids, because of their anti- inflammatory actions, have been used to modify the course of CLD. There have been almost 40 randomised controlled trials of postnatal dexamethasone and 12 of inhaled steroids. more...
Geography:
Northern Ireland
Paediatr Respir Rev,
Vol: 5 Suppl A Page: S245-8 2004
H. L. Halliday
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This article discusses the dilemma using postnatal steroids poses for the dilemma for the neonatologist
Geography:
Northern Ireland
Acta Paediatr,
Vol: 90 Page: 116-8 February 2001
H. L. Halliday
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The aim of this study was to examine if predictive values of high risk markers Apgar, acidosis and others - would be increased if early continuous electroencephalographic monitoring allowed accurate identification of all neonatal seizures
Abstract:
BACKGROUND: After perinatal asphyxia, predicting which infants will develop significant hypoxic-ischemic encephalopathy and neonatal seizures remains a difficult task. High-risk markers (Apgar score, acidosis, nucleated red blood cells, and resuscitation) have been used to predict neonatal seizures with varying success. The "3 strikes" of Apgar score of <5 at 5 minutes, pH more...
International Classification:
Neonatal seizures
Categories:
neonatal seizures; encephalopathy
Geography:
Republic of Ireland
Pediatrics,
Vol: 118 Page: 41-6 July 2006
D. M. Murray; C. A. Ryan; G. B. Boylan; A. P. Fitzgerald; S. Connolly
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The aim of this study was to describe gender difference in the prescription of oral corticosteroids in asthmatic children
Abstract:
AIMS: To determine if there is a gender difference in the prescription of oral corticosteroids in asthmatic children (< 15 years). METHODS: 8072 asthmatics were identified on the basis that they received a prescription for either an inhaled beta-adrenoceptor agonist, an inhaled corticosteroid, inhaled cromoglycate/nedocromil sodium, oral xanthines or leukotriene antagonist. Odds ratios more...
International Classification:
Diseases of the respiratory system - Chronic lower respiratory diseases - asthma
Categories:
asthma
Geography:
Republic of Ireland
Br J Clin Pharmacol,
Vol: 52 Page: 319-21 September 2001
D. Williams; A. Kelly; J. Feely
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The aim of this study was to quantify the risk of adverse perinatal outcomes birth defects and pregnancy complications following assisted reproductive technology
Abstract:
BACKGROUND: Increasing use of fertility therapy has elicited concerns regarding adverse effects for expectant mothers and the health of children thus conceived. AIMS: To study the risk of adverse perinatal outcomes, birth defects and pregnancy complications following assisted reproductive technology (ART). METHODS: Questionnaire-based study involving 1,524 children and 1,182 pregnancies more...
International Classification:
Pregnancy, childbirth and the puerperium
Categories:
assisted reproductive technology
Geography:
International
Ir J Med Sci,
Vol: 177 Page: 233-41 September 2008
C. Allen; S. Bowdin; R. F. Harrison; A. G. Sutcliffe; L. Brueton; G. Kirby; J. Kirkman-Brown; C. Barrett; W. Reardon; E. Maher
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The aim of this study was to examine health outcomes in women infected with Hep C type 1b during pregnancy with a matched control group
Abstract:
A large cohort of rhesus-negative women in Ireland were inadvertently infected with hepatitis C virus following exposure to contaminated anti-D immunoglobulin in 1977-8. This major iatrogenic episode was discovered in 1994. We studied 36 women who had been infected after their first pregnancy, and compared them to an age- and parity-matched control group of rhesus-positive women. The more...
International Classification:
Certain infectious and parasitic diseases - Viral hepatitis - hepatitis C
Categories:
hepatitis C type 1b; health outcomes
Geography:
Republic of Ireland
Qjm,
Vol: 93 Page: 597-601 September 2000
T. Jabeen; B. Cannon; J. Hogan; M. Crowley; C. Devereux; L. Fanning; E. Kenny-Walsh; F. Shanahan; M. J. Whelton
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This article discusses prenatal diagnosis of heart disease
Geography:
the United Kingdom
Rev Port Cardiol,
Vol: 19 Page: 213-4 February 2000
R. Anjos
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The aim of this study was to assess preprandial and postprandial capillary glucose monitoring in pregnant women with type 1 diabetes
Abstract:
OBJECTIVE: This study was undertaken to compare preprandial and postprandial capillary glucose monitoring in pregnant women with type 1 diabetes. STUDY DESIGN: Sixty-one women with type 1 diabetes were randomly assigned at 16 weeks' gestation to preprandial or postprandial blood glucose monitoring using memory-based glucose reflectance meters throughout pregnancy. Serial measurements of more...
International Classification:
Evaluation of the effectiveness of two time points of glucoses monitoring
Categories:
glucose monitoring in pregnant women with type 1 diabetes
Geography:
Northern Ireland
Am J Obstet Gynecol,
Vol: 189 Page: 507-12 August 2003
J. G. Manderson; C. C. Patterson; D. R. Hadden; A. I. Traub; C. Ennis; D. R. McCance
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This case report discusses the lactobacilli and bifidobacteria microbiota in the human ileum at a very early stage of life
Abstract:
The overall purpose of this study was to examine the lactobacilli and bifidobacteria microbiota in the human ileum at a very early stage of life. Ileostomy effluents from two infants, taken at different time points, were plated on Lactobacillus selective agar and cys-MRS containing mupirocin to select for bifidobacteria. In one case, a stool sample following ileostomy reversal was more...
International Classification:
Certain infectious and parasitic diseases - Report
Categories:
ileum lactobacilli and bifidobacteria microbiota infection
Geography:
Republic of Ireland
Isme J,
Vol: 2 Page: 83-91 January 2008
R. Wall; S. G. Hussey; C. A. Ryan; M. O'Neill; G. Fitzgerald; C. Stanton; R. P. Ross
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This article discusses preterm birth
Geography:
Republic of Ireland
Clin Evid,
December 2002
B. Byrne; J. J. Morrison
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This article discusses how preterm delivery and its short-term and long-term sequelae constitute a serious problem in terms of mortality, disability, and cost to society
Abstract:
Preterm delivery and its short-term and long-term sequelae constitute a serious problem in terms of mortality, disability, and cost to society. The incidence of preterm delivery, which has increased in recent years, is associated with various epidemiological and clinical risk factors. Results of randomised controlled trials suggest that attempts to reduce these risk factors by use of more...
Geography:
Republic of Ireland
Lancet,
Vol: 360 Page: 1489-97 November 2002
M. M. Slattery; J. J. Morrison
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The aim of this study was to examine the prevalence of hepatitis B exposure in the population of the Republic of Ireland, by measuring the prevalence of hepatitis B anti-core antibody in oral fluid collected by postal survey
Abstract:
The aim of this study was to estimate the prevalence of hepatitis B exposure in the population of the Republic of Ireland, by measuring the prevalence of hepatitis B anti-core antibody in oral fluid collected by postal survey. A random multi-stage stratified sample of Irish households was obtained, using the Irish electoral register as the sampling frame. A total of 962 households were more...
International Classification:
Certain infectious and parasitic diseases - Viral hepatitis - hepatitis B
Categories:
hepatitis C B anti-core antibody
Geography:
Republic of Ireland
Epidemiol Infect,
Vol: 125 Page: 701-4 December 2000
T. O'Connell; L. Thornton; D. O'Flanagan; A. Staines; J. Connell; S. Dooley; G. McCormack
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This article discusses preventing perinatal transmission of HIV
Geography:
the United Kingdom
Adv Exp Med Biol,
Vol: 549 Page: 149-54 2004
L. A. Van der Poel; H. Lyall
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This article discusses the prevention strategies of chronic lung disease
Geography:
Northern Ireland
Pediatr Pulmonol Suppl,
Vol: 26 Page: 103-5 2004
H. L. Halliday
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The aim of this study was to investigate variations in standards of neonatal care in the first week of life that might have contributed to deaths in infants who were born at 27 and 28 weeks' gestation.
Abstract:
OBJECTIVE: To identify variations in standards of neonatal care in the first week of life that might have contributed to deaths in infants who were born at 27 and 28 weeks' gestation. METHODS: A case-control study was conducted of infants who were born at 27 and 28 weeks' gestation in England, Wales, and Northern Ireland during a 2-year period. Cases were neonatal deaths; control more...
International Classification:
Deaths - infants
Categories:
neonatal care; -deaths in infants
Geography:
the United Kingdom
Pediatrics,
Vol: 116 Page: 1457-65 December 2005
D. Acolet; D. Elbourne; N. McIntosh; M. Weindling; M. Korkodilos; J. Haviland; J. Modder; M. Macintosh
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The aim of this study was to assess the efficacy and optimal dose of prophylactic intravenous ephedrine for the prevention of maternal hypotension associated with spinal anaesthesia for Caesarean section
Abstract:
BACKGROUND AND OBJECTIVE: To evaluate the efficacy and optimal dose of prophylactic intravenous ephedrine for the prevention of maternal hypotension associated with spinal anaesthesia for Caesarean section. METHODS: After patients had received an intravenous preload of 0.5 L of lactated Ringer's solution, spinal anaesthesia was administered in the sitting position with hyperbaric more...
International Classification:
Evaluation of the effectiveness of two treatments-for the prevention of maternal hypotension
Categories:
maternal hypotension
Geography:
Republic of Ireland
Eur J Anaesthesiol,
Vol: 19 Page: 63-8 January 2002
J. P. Loughrey; F. Walsh; J. Gardiner
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This study examined the use of perioperative antimicrobial therapy in general surgery
Abstract:
BACKGROUND: Perioperative antimicrobial therapy has demonstrated efficacy in reducing the rate of surgical site infections in clinical trials. With the emergence of antibiotic resistance, the risk of reaction, and the inevitable financial repercussions, use of prophylactic antibiotics is not a panacea, and their misuse may have considerable implications. The aim of this study was to more...
International Classification:
Procedure - perioperative antimicrobial therapy
Categories:
perioperative antimicrobial therapy
Geography:
Republic of Ireland
Surg Infect (Larchmt),
Vol: 7 Page: 355-60 August 2006
B. G. Fennessy; M. J. O'Sullivan; G. J. Fulton; W. O. Kirwan; H. P. Redmond
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The aim of this study was to examine incidence of severe hyperbilirubinaemia in the newborn and to identify associated clinical and demographic variables and short term outcomes in the United Kingdom and Ireland
Abstract:
OBJECTIVES: To determine the incidence of severe hyperbilirubinaemia in the newborn, and to identify associated clinical and demographic variables, and short-term outcomes. DESIGN: Prospective, population-based study. SETTING: UK and Republic of Ireland, between 1 May 2003 and 31 May 2005. PARTICIPANTS: Infants in the first month of life with severe hyperbilirubinaemia (maximum more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified - Symptoms and signs involving the digestive system and abdomen - hyperbilirubinaemia
Categories:
hyperbilirubinaemia
Geography:
Republic of Ireland and the United Kingdom
Archives of Disease in Childhood -- Fetal & Neonatal Edition,
Vol: 92 Page: F342-6 2007
D. Manning; P. Todd; M. Maxwell; M. J. Platt
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The aim of the study was to determine the effects of age and diet (breast milk, formula milk and weaning diet) on metabolic activities in faecal samples from infants aged 1 week to 1 year
Abstract:
The aim of the present study was to determine the effects of age and diet (breast milk, formula milk and weaning diet) on metabolic activities in faecal samples from infants aged 1 week to 1 year, and to compare these findings with activities found in samples from adults. Such activities can provide valuable information on functional changes in the microbiota that may have significance more...
International Classification:
Breastfeeding +/- formulae milk
Categories:
metabolic activities in faecal samples
Geography:
Northern Ireland
Br J Nutr,
Vol: 89 Page: 509-15 April 2003
P. M. Heavey; S. A. Savage; A. Parrett; C. Cecchini; C. A. Edwards; I. R. Rowland
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This case report discusses a preterm infant who developed pseudomonas endophthalmitis, septicemia, and meningitis after a corneal abrasion.
Abstract:
Bacterial endophthalmitis is rare in the neonatal period. It occurs in susceptible individuals such as preterm infants. Pseudomonas aeruginosa, a Gram-negative bacillus, has been identified as the causative organism in more than 75% of invasive neonatal eye infections. The source may be endogenous; secondary to septicemia or exogenous, including reports of nosocomial infections and more...
International Classification:
Diseases of the eye and adnexa - Report
Categories:
corneal abrasion
Geography:
Republic of Ireland
J Aapos,
Vol: 9 Page: 288-9 June 2005
M. O'Keefe; L. Nolan; B. Lanigan; J. Murphy
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The aim of this study was to estimate the societal costs of extreme premature birth during the 6th year after birth
Abstract:
BACKGROUND: Previous assessments of the economic impact of preterm birth focussed on short term health service costs across the broad spectrum of prematurity. OBJECTIVE: To estimate the societal costs of extreme preterm birth during the sixth year after birth. METHODS: Unit costs were applied to estimates of health, social and broader resource use made by 241 children born at 20 through more...
International Classification:
Economic - Extreme premature birth
Categories:
premature birth
Geography:
Republic of Ireland and the United Kingdom
Early Hum Dev,
Vol: 82 Page: 77-84 February 2006
S. Petrou; J. Henderson; M. Bracewell; C. Hockley; D. Wolke; N. Marlow
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The aim of this study was to examine celiac artery flow to left ventricular output ratio (CAF:LVO) in the presence and the absence of a patent ductus arteriosus in preterm neonates, and to compare CAF:LVO to current echocardiographic markers
Abstract:
BACKGROUND: Determining the significance of a patent ductus arteriosus (PDA) remains difficult in preterm neonates and current echocardiographic markers give little information about ductal steal. We hypothesized that the relationship between celiac artery flow (CAF) and left ventricular output (LVO) in the presence of a PDA may determine haemodynamic significance. OBJECTIVES: To more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Congenital malformations of the circulatory system - patent ductus arteriosus
Categories:
left ventricular output ratio; - patent ductus arteriosus
Geography:
Republic of Ireland
Neonatology,
Vol: 93 Page: 206-12 2008
A. El-Khuffash; M. Higgins; K. Walsh; E. J. Molloy
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The aim of this study was to undertake an audit of neonatal practice in intensive care and in all other units caring for newborn infants
Abstract:
As part of a process of audit of neonatal practice, a questionnaire on clinical practice and priorities which need to be addressed was sent to all consultant neonatologists, and to a consultant paediatrician in all other units caring for newborn infants, in the Republic of Ireland. The response rate was 88% (22 out of 25 replied). Thirteen respondents specified greater than 24 weeks more...
International Classification:
Factors influencing health status and contact with health services - persons encountering health services for examination and investigation - intensive care neonatal practice
Categories:
intensive care neonatal practice
Geography:
Republic of Ireland
Ir Med J,
Vol: 94 Page: 74-6, 78 March 2001
T. Hussein; T. Clarke; H. A. Girim; T. Matthews
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This article discusses pain assessment in neonates
Geography:
Republic of Ireland
Paediatr Anaesth,
Vol: 18 Suppl 1 Page: 4-13 May 2008
R. Howard; B. Carter; J. Curry; N. Morton; K. Rivett; M. Rose; J. Tyrrell; S. Walker; G. Williams
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This case report discusses respiratory distress in a newborn infant
International Classification:
Diseases of the respiratory system - Report
Categories:
respiratory distress
Geography:
Republic of Ireland
Arch Pediatr Adolesc Med,
Vol: 155 Page: 523-4 April 2001
J. G. Walsh; M. J. O'Sullivan; C. A. Ryan
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The aim of this study was to assess neurologic, educational, and psychological status in adolescence of neonates enrolled in a double-blind, randomized, controlled trial of dexamethasone therapy for chronic lung disease
Abstract:
OBJECTIVES: To study neurologic, educational, and psychological status in adolescence of neonates enrolled in a double-blind, randomized, controlled trial of dexamethasone therapy for chronic lung disease. PARTICIPANTS: A total of 287 infants who were chronically dependent on supplementary oxygen and were 2 to 12 weeks of age were recruited from 31 centers in 6 countries to a more...
International Classification:
Evaluation of the effectiveness of treatments - chronic lung disease on later life neurological outcomes
Categories:
outcomes on trial of dexamethasone therapy for chronic lung disease
Geography:
Republic of Ireland and the United Kingdom
Pediatrics,
Vol: 116 Page: 370-8 August 2005
R. A. Jones
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The aim of this study was to assess the growth, health status, and respiratory outcomes at 13 to 17 years of infants enrolled in a double-blind, randomized, controlled trial of dexamethasone for the treatment of neonatal chronic lung disease
Abstract:
OBJECTIVES: To study the growth, health status, and respiratory outcomes at 13 to 17 years of infants enrolled in a double-blind, randomized, controlled trial of dexamethasone for the treatment of neonatal chronic lung disease. PARTICIPANTS: A total of 287 infants who were chronically dependent on supplementary oxygen between 2 and 12 weeks of age were recruited from 31 centers in 6 more...
International Classification:
Evaluation of the effectiveness of treatments - neonatal chronic lung
Categories:
treatment of neonatal chronic lung disease
Geography:
Republic of Ireland and the United Kingdom
Pediatrics,
Vol: 116 Page: 379-84 August 2005
R. A. Jones
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The aim of this study was to examine application of the novel technique of glycosylase mediated polymorphism detection to the detection of two of the most common mutations of the PAH gene in the Irish population that cause phenylketonuria, R408W and I65T,
Abstract:
Mutation detection methods based upon chemical or enzymatic cleavage of DNA offer excellent detection efficiencies coupled with high throughput and low unit cost. We describe the application of the novel technique of Glycosylase Mediated Polymorphism Detection (GMPD) to the detection of two of the most common mutations of the PAH gene in the Irish population that cause phenylketonuria more...
International Classification:
Endocrine, nutritional and metabolic diseases - Metabolic disorders - phenylketonuria
Categories:
glycosylase mediated polymorphism detection; -phenylketonuria; R408W; I65T;
Geography:
Republic of Ireland
Hum Mutat,
Vol: 17 Page: 432 May 2001
K. A. O'Donnell; O. Tighe; C. O'Neill; E. Naughten; P. D. Mayne; T. V. McCarthy; P. Vaughan; D. T. Croke
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We evaluated the incidence of readmission with respiratory syncytial virus infection among the graduates of a regional Neonatal Intensive Care Unit, and characterized those who were rehospitalized
Abstract:
We evaluated the incidence of readmission with respiratory syncytial virus (RSV) infection among the graduates of a regional Neonatal Intensive Care Unit (NICU), and characterized those who were rehospitalized. These data were used as a predictive tool to estimate the number of babies likely to suffer readmission with RSV for the year 2000 cohort. Using the published efficacies of more...
International Classification:
Economic - Health service provision-readmissions
Categories:
respiratory syncytial virus
Geography:
Northern Ireland
Pediatr Pulmonol,
Vol: 34 Page: 262-6 October 2002
J. McCormick; R. Tubman
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This article discusses recent clinical trials of neonatal surfactant treatment and report their findings
Abstract:
OBJECTIVE: To search for recent clinical trials of neonatal surfactant treatment and report their findings. METHODS: Recent was defined as published between 2000 and 2005. An online search on PubMed was made on 30th December 2005 using the following terms: surfactant treatment, clinical trials and neonate, with limits of years 2000 to 2005 and age - newborn from birth to 1 month. more...
Geography:
Northern Ireland
Biol Neonate,
Vol: 89 Page: 323-9 2006
H. L. Halliday
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The aim of this study was to improve primary treatment, prevention, and control of infection caused by Chlamydia trachomatis and Neisseria gonorrhoeae, by undertaking an analysis of all cases presenting in a time- and geographical-frame
Abstract:
BACKGROUND: Chlamydia trachomatis and Neisseria gonorrhoeae are two important and frequently overlooked causes of neonatal and adult conjunctivitis. OBJECTIVES AND METHODS: In order to improve primary treatment, prevention, and control of infection caused by these organisms, an analysis of all cases presenting from July 2002 to December 2006 at a major Irish regional teaching hospital more...
International Classification:
Bacterium - Chlamydia trachomatis
Categories:
Chlamydia trachomatis; Neisseria gonorrhoeae
Geography:
Republic of Ireland
Int J Infect Dis,
Vol: 12 Page: 371-3 July 2008
M. Quirke; A. Cullinane
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This case report 2 mutations, E255- and G291D, identified in the nicotinamide adenine dinucleotide -binding lobe of cytb(5)r in previously reported patients, and detection of a further novel mutation, D239G, in this lobe in two unrelated Irish families
Abstract:
Type I recessive congenital methaemoglobinaemia (RCM), caused by the reduced form of nicotinamide adenine dinucleotide (NADH)-cytochrome b(5) reductase (cytb(5)r) deficiency, manifests clinically as cyanosis without neurological dysfunction. Two mutations, E255- and G291D, have been identified in the NADH-binding lobe of cytb(5)r in previously reported patients, and we have detected a more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Report
Categories:
mutations of the nicotinamide adenine dinucleotide -binding lobe of cytb(5)r
Geography:
Northern Ireland
Br J Haematol,
Vol: 129 Page: 847-53 June 2005
M. J. Percy; L. J. Crowley; C. A. Davis; M. F. McMullin; G. Savage; J. Hughes; C. McMahon; R. J. Quinn; O. Smith; M. J. Barber; T. R. Lappin
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This case report discusses a case of recurrent congenital haemangiopericytoma in a child
Abstract:
A five-day-old boy was referred with a soft-tissue mass in his right upper arm. Plain radiographs and ultrasound demonstrated a lesion extending from the axilla to the elbow on the posterolateral aspect of the humerus. Open biopsy confirmed the diagnosis of congenital haemangiopericytoma. After MRI and selective angiography, excision biopsy was carried out, but no adjuvant therapy was more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Report
Categories:
congenital haemangiopericytoma
Geography:
Republic of Ireland
J Bone Joint Surg Br,
Vol: 83 Page: 269-72 March 2001
T. M. O'Donnell; A. T. Devitt; S. Kutty; E. E. Fogarty
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The aim of this study was to examine if caudal epidural anaesthesia would allow reduction of an incarcerated inguinal hernia in the acute setting, thereby obviating the need for intravenous sedation
Abstract:
Incarcerated inguinal hernias in infants are commonly encountered. Reduction with intravenous sedation using morphine and related drugs carries risks of apnoea and/or respiratory arrest, especially in small, ex-premature babies who have an increased incidence of incarceration and thus opiate use is best avoided. Caudal epidural anaesthesia is widely used as pre- and post-operative more...
International Classification:
Procedure - surgery
Categories:
incarcerated inguinal hernia
Geography:
Northern Ireland
Pediatr Surg Int,
Vol: 21 Page: 715-7 September 2005
N. Brindley; R. Taylor; S. Brown
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The aim of this study was to explore regional variations in Extracorporeal membrane oxygenation referrals and neonatal deaths due to severe respiratory failure in England, Wales and Northern Ireland
Abstract:
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) remains the mainstay of management in neonates with severe but potentially reversible respiratory failure. In the UK, ECMO is available only as a supraregional service at four centres. OBJECTIVE: To explore regional variations in ECMO referrals and neonatal deaths due to severe respiratory failure in England, Wales and Northern more...
International Classification:
Health service provision
Categories:
severe respiratory failure
Geography:
the United Kingdom
Arch Dis Child Fetal Neonatal Ed,
Vol: 93 Page: F104-7 March 2008
R. Tiruvoipati; H. Pandya; B. Manktelow; J. Smith; I. Dodkins; D. Elbourne; D. Field
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This study compared the incidence of renal scarring in infants with high grade vesicoureteral reflux in those presenting with and without urinary tract infection
Abstract:
PURPOSE: We compared the incidence of renal scarring in infants with high grade vesicoureteral reflux in those presenting with and without urinary tract infection. METHODS AND METHODS: We reviewed the medical records of 81 male and 46 female infants (194 renal refluxing units) with a mean age of 4 months who had grade IV or V primary vesicoureteral reflux and underwent an anti-reflux more...
International Classification:
Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux
Categories:
vesicoureteral reflux
Geography:
Republic of Ireland
J Urol,
Vol: 166 Page: 648-50 August 2001
B. Sweeney; S. Cascio; M. Velayudham; P. Puri
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This study evaluated the incidence of renal damage in a large series of male infants with high grade vesicoureteral reflux diagnosed after the first urinary tract infection
Abstract:
PURPOSE: Vesicoureteral reflux during infancy is found mainly in males, and it is of high grade and often bilateral. The higher predominance of male infants is reported in series when the reflux is diagnosed prenatally and when it is detected after urinary tract infection. Renal parenchymal damage may already be present at birth before any episode of urinary tract infection or acquired more...
International Classification:
Diseases of the genitourinary system - Other diseases of urinary system-urinary tract infection
Categories:
urinary tract infection
Geography:
Republic of Ireland
J Urol,
Vol: 168 Page: 1708-10; discussion 1710 October 2002
S. Cascio; B. Chertin; E. Colhoun; P. Puri
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The aim of this study was to compare the incidence of renal damage in siblings of patients with vesicoureteric reflux presenting with documented history of urinary tract infection with asymptomatic siblings who were diagnosed with reflux
Abstract:
AIM: To compare the incidence of renal damage in siblings of patients with vesicoureteric reflux (VUR) who presented with a documented history of urinary tract infection (UTI) with asymptomatic siblings who were diagnosed with reflux during a screening programme for hereditary VUR. METHODS: Medical and radiological records of the VUR patients (1990-2000) were examined for age, gender, more...
International Classification:
Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux
Categories:
vesicoureteric reflux
Geography:
Republic of Ireland
Acta Paediatr,
Vol: 92 Page: 17-20 2003
S. Cascio; A. Yoneda; B. Chertin; E. Colhoun; P. Puri
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The aim of this study was to examine 5-year renal transplant survival in the United Kingdom
Abstract:
RENAL TRANSPLANT OUTCOME: Analysis of 5-year transplant survival in the UK showed a number of significant factors influencing outcome of adult cadaveric renal transplantation. Data from 5,963 first grafts and 1,078 regrafts carried out between 1990-1997 showed year of graft, recipient age and diabetes, donor age, kidney exchange between centres and HLA matching to influence 5-year more...
International Classification:
Organ transplants
Categories:
transplant survival
Geography:
Republic of Ireland and the United Kingdom
Clin Transpl,
2000
R. J. Johnson; M. A. Belger; J. D. Briggs; S. V. Fuggle; P. J. Morris
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The aim of this study was to estimate the probability that a second infant death is natural versus unnatural
Abstract:
BACKGROUND: There have been suggestions that when two or three unexpected unexplained infant deaths occur within a family they are more likely to be unnatural than natural. We aimed to estimate the probability that a second infant death is natural versus unnatural. METHODS: The Care of Next Infant programme (CONI) supports parents who have previously had an unexpected and apparently more...
International Classification:
Deaths - in one family
Categories:
infant mortality
Geography:
the United Kingdom
Lancet,
Vol: 365 Page: 29-35 2005 Jan 1-7
R. G. Carpenter; A. Waite; R. C. Coombs; C. Daman-Willems; A. McKenzie; J. Huber; J. L. Emery
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This study reports on reptile-associated Salmonellosis in residents in the South East of Ireland 2005 - 2007
International Classification:
Surveillance - Certain infectious and parasitic diseases - Intestinal infectious diseases - Salmonellosis
Categories:
reptile-associated Salmonellosis
Geography:
Republic of Ireland
Euro Surveill,
Vol: 13 Page: April 2008
A. M. O'Byrne; M. Mahon
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The aim of this study was to evaluate the effect of age, CD4 percentage (CD4%) and plasma HIV-1 RNA on response to highly active antiretroviral therapy in previously untreated children
Abstract:
OBJECTIVE: To evaluate the effect of age, CD4 percentage (CD4%) and plasma HIV-1 RNA on response to highly active antiretroviral therapy (HAART) in previously untreated children. DESIGN: Cohort study. METHODS: We examined the association between age at HAART initiation, and CD4 and HIV-1 RNA response using logistic and Cox regression, adjusting for sex, route of infection and pre-HAART more...
International Classification:
Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV
Categories:
HIV-1 - antiretroviral therapy
Geography:
Republic of Ireland and the United Kingdom
Aids,
Vol: 18 Page: 1915-24 September 2004
A. S. Walker; K. Doerholt; M. Sharland; D. M. Gibb
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This article discusses resuscitation of extremely preterm and/or low-birth-weight infants
Abstract:
Since ancient times, various methods have been used to revive apparently stillborn infants; many were of dubious efficacy and had the potential to cause harm. Based largely on studies of acutely asphyxiated term animal models, clinical assessment and positive pressure ventilation have become the cornerstones of neonatal resuscitation over the last 40 years. Over the last 25 years, care more...
Geography:
Republic of Ireland
Neonatology,
Vol: 93 Page: 295-301 2008
C. P. O'Donnell
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The aim of this study was to examine optic disc characteristics in premature infants with and without ischaemic brain injury
Abstract:
AIMS: To assess optic disc characteristics in premature infants with and without ischaemic brain injury and to evaluate the role of optic disc morphology in dating the injury. METHODS: RetCam fundal images, cranial ultrasounds and magnetic resonance imaging (MRI) of 109 premature infants were analysed. The study cohort was divided into subgroups depending on the presence or absence of more...
International Classification:
Premature - infants
Categories:
optic disc; premature infants; ischaemic brain injury
Geography:
Republic of Ireland
Br J Ophthalmol,
Vol: 90 Page: 465-71 April 2006
E. McLoone; M. O'Keefe; V. Donoghue; S. McLoone; N. Horgan; B. Lanigan
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This article discusses available data regarding the safety of biological therapies during pregnancy, primarily in woman with inflammatory bowel disease
Abstract:
BACKGROUND: One of the most frequently asked questions during consultation with those affected by inflammatory bowel disease is what are its effects on pregnancy, and how the treatment will impact on conception and pregnancy outcomes. AIM: To review available data regarding the safety of biological therapies during pregnancy, primarily in woman with inflammatory bowel disease. METHODS: more...
Geography:
Republic of Ireland
Aliment Pharmacol Ther,
Vol: 27 Page: 885-94 May 2008
S. O'Donnell; C. O'Morain
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These case report discuss 4 cases of rhombencephalosynapsis with correlation of prenatal and postnatal imaging and autopsy findings
Abstract:
OBJECTIVES: Rhombencephalosynapsis is a rare, but increasingly recognized, brain malformation characterized by congenital fusion of the cerebellar hemispheres and absence of the vermis. Rhombencephalosynapsis is associated with significant developmental delay, seizures and involuntary head movements. We report four cases, with correlation of prenatal and postnatal imaging and autopsy more...
International Classification:
Other-rhombencephalosynapsis
Categories:
rhombencephalosynapsis
Geography:
Republic of Ireland
Ultrasound Obstet Gynecol,
Vol: 31 Page: 542-8 May 2008
F. McAuliffe; D. Chitayat; W. Halliday; S. Keating; V. Shah; M. Fink; O. Nevo; G. Ryan; P. Shannon; S. Blaser
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The aim of this study was to examine caesarean rates in a maternity hospital
International Classification:
Pregnancy, childbirth and the puerperium - caesarean rates
Categories:
caesarean rates
Geography:
Republic of Ireland
Bjog,
Vol: 110 Page: 346-9 April 2003
T. G. Matthews; P. Crowley; A. Chong; P. McKenna; C. McGarvey; M. O'Regan
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This article discusses rising cesarean rates
Geography:
Republic of Ireland
Bjog,
Vol: 110 Page: 966 October 2003
C. Burke; M. Skehan; T. Stack; G. Burke
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