Irish Child Health Database - Peer Reviewed Papers
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The aim of this study was to determine the incidence and persistence of neonatal brachial plexus paralysis and evaluated whether its occurrence could be predicted by maternal characteristics or partographic analysis in a large cohort of recent cases
Abstract:
OBJECTIVE: Brachial plexus paralysis is a serious form of neonatal morbidity. We determined its incidence and persistence of disability and evaluated whether its occurrence could be predicted by maternal characteristics or partographic analysis in a large cohort of recent cases. STUDY DESIGN: During the years 1994 through 1998, all infants with neonatal evidence of obstetric brachial more...
International Classification:
Certain conditions originating in the perinatal period - brachial plexus paralysis
Categories:
maternal characteristics or partographic analysis; -neonatal brachial plexus paralysis
Geography:
Republic of Ireland
Am J Obstet Gynecol,
Vol: 187 Page: 1209-12 November 2002
V. Donnelly; A. Foran; J. Murphy; P. McParland; D. Keane; C. O'Herlihy
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This study examined the incidence of newly diagnosed contralateral reflux after endoscopic correction of unilateral reflux and identified possible risk factors for its development
Abstract:
PURPOSE: As more and more pediatric urologists use endoscopic therapy as a primary treatment option for vesicoureteral reflux, newer indications for this procedure are being considered. Recently it was suggested that contralateral nonrefluxing ureters should be treated prophylactically in patients undergoing unilateral endoscopic correction of vesicoureteral reflux. We analyzed the more...
International Classification:
Procedure - endoscopic correction and contralateral reflux
Categories:
contralateral reflux
Geography:
Republic of Ireland
J Urol,
Vol: 178 Page: 1711-3 October 2007
M. Menezes; N. Mohanan; J. Haroun; E. Colhoun; P. Puri
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The aim of this study was to examine the association between catechol-O-methyltransferase gene polymorphism and attention deficit hyperactivity disorder in an Irish sample
Abstract:
Pharmacological and biochemical studies have indicated that imbalances in dopaminergic transmission may contribute to the aetiology of attention deficit hyperactivity disorder (ADHD). The enzyme catechol-O-methyltransferase (COMT) plays a key role in the degradation of catecholamines such as dopamine, L-DOPA, adrenaline, and noradrenaline and therefore could be considered as a candidate more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
Republic of Ireland
Am J Med Genet,
Vol: 96 Page: 282-4 June 2000
Z. Hawi; N. Millar; G. Daly; M. Fitzgerald; M. Gill
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This article discusses known chromosome alterations and the candidate genes residing in the altered region, as well as syndromes associated with neural tube defects and causative genes, if known
Abstract:
Although most neural tube defects (anencephaly, spina bifida) occur as isolated malformations, a substantial proportion are attributable to chromosome anomalies, known teratogens, or component manifestations of multiple anomaly syndromes. This review describes known chromosome alterations and the candidate genes residing in the altered region, as well as syndromes associated with neural more...
Geography:
Republic of Ireland
Am J Med Genet C Semin Med Genet,
Vol: 135C Page: 69-76 May 2005
S. A. Lynch
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This study reports a norovirus outbreak associated in a hotel in the west of Ireland in 2006
Abstract:
An outbreak of gastrointestinal disease (nausea, vomiting or diarrhoea) occurred among a party of wedding guests, staff and other guests in a hotel in the west of Ireland, in October 2006. Upon notification, a multi-disciplinary outbreak control team was convened to investigate and control the outbreak. In all, 98 people were ascertained ill. The median duration of illness was 48 hours. more...
International Classification:
Surveillance - International committee on Taxonomy of Viruses - norovirus
Categories:
norovirus
Geography:
Republic of Ireland
Euro Surveill,
Vol: 12 Page: E11-2 July 2007
A. Michel; R. Fitzgerald; D. Whyte; A. Fitzgerald; E. Beggan; N. O'Connell; T. Greally
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This study investigated the obstetric antecedents for preterm delivery in an Irish urban obstetric population, and to evaluate the incidence and outcome of such deliveries
Abstract:
Abstract Objectives: To investigate the obstetric antecedents for preterm delivery (PTD) in an Irish urban obstetric population, and to evaluate the incidence and outcome of such deliveries. Study design: A retrospective observational study of all preterm deliveries at the Rotunda Hospital, Dublin during the six-year period 1997-2002. The findings for early preterm deliveries (EPTD) more...
International Classification:
Pregnancy, childbirth and the puerperium - obstetric antecedents for preterm delivery
Categories:
obstetric antecedents for preterm delivery
Geography:
Republic of Ireland
Journal of Perinatal Medicine,
Vol: 36 Page: 306-309 2008
M. M. Slattery; M. Geary; J. J. Morrison
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The aim of this study was to examine vertical transmission rates of hepatitis C in 2 tertiary level maternity units
Abstract:
OBJECTIVE: The objective of the study was to determine vertical transmission rates of hepatitis C in 2 tertiary level maternity units. STUDY DESIGN: This was a retrospective review of all hepatitis C-positive mothers and their pregnancy outcomes. RESULTS: Of 74,629 deliveries, 559 liveborn infants were born to 545 hepatitis C mothers; the rate of antenatal hepatitis C infection was more...
International Classification:
Certain infectious and parasitic diseases - Viral hepatitis - hepatitis C
Categories:
vertical transmission rates of hepatitis C
Geography:
Republic of Ireland
Am J Obstet Gynecol,
Vol: 199 Page: 315 e1-5 September 2008
M. B. McMenamin; A. D. Jackson; J. Lambert; W. Hall; K. Butler; S. Coulter-Smith; F. M. McAuliffe
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The aim of this study was to examine the extent of consultant-diagnosed toxocaral eye disease among a population of schoolchildren
Abstract:
Ocular toxocariasis in humans is typically a unilateral disease caused by second-stage larvae of the Toxocara species. Serological evidence of widespread infection in humans provides little information on clinical disease. There is only a single previous estimate of the prevalence of ocular toxocariasis (from Alabama). The present survey examined the extent of consultant-diagnosed more...
International Classification:
Certain infectious and parasitic diseases - Helminthiases - toxocaral eye disease
Categories:
consultant-diagnosed toxocaral eye disease
Geography:
Republic of Ireland
Clin Infect Dis,
Vol: 39 Page: 173-8 July 2004
B. Good; C. V. Holland; M. R. Taylor; J. Larragy; P. Moriarty; M. O'Regan
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This aim of this study was to screen for transfusion-transmitted hepatitis C
Abstract:
BACKGROUND: An optional (general) HCV testing program for blood and blood component recipients before the introduction of routine donor anti-HCV screening (October 1991) was launched in Ireland in 1995 to complement the targeted lookback program in progress at that time and to identify transfusion-transmitted hepatitis C. STUDY DESIGN AND METHODS: The public were informed of the more...
International Classification:
Certain infectious and parasitic diseases - Viral hepatitis - hepatitis C
Categories:
transfusion-transmitted hepatitis C
Geography:
Republic of Ireland
Transfusion,
Vol: 42 Page: 1501-6 November 2002
A. Davoren; A. D. Dillon; J. P. Power; J. Donnellan; J. M. Quinn; J. W. Willis; E. M. Lawlor; J. M. O'Riordan
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This article discusses the management of Paediatric aphakic glaucoma
Abstract:
CONTEXT: Aphakic glaucoma is a serious, sight-threatening complication in children who remain aphakic following congenital cataract surgery. The reported incidence varies from 15% to 45% and it has a higher incidence in small eyes and in babies who undergo surgery before 4 weeks of age. Most cases take the form of open-angle glaucoma. Despite careful monitoring, diagnostic difficulties more...
Geography:
Republic of Ireland
Acta Ophthalmol Scand,
Vol: 84 Page: 734-9 December 2006
C. Kirwan; M. O'Keefe
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These case reports discuss four cases of paediatric trauma associated with All-Terrain vehicles
Abstract:
All-terrain vehicles (ATVs) are used extensively in the agricultural and forestry industries where they are marketed as an inexpensive alternative to tractors. Recent years have seen an increase in recreational use of ATVs, particularly quad bikes. More worrying is the increased use of privately owned ATVs among the paediatric population. In Ireland it is a legal requirement to provide more...
International Classification:
Injury, poisoning and certain other consequences of external causes
Categories:
vehicle injuries
Geography:
Republic of Ireland
Ir Med J,
Vol: 101 Page: 55-7 February 2008
J. Curran; C. O'Leary
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The aim of this study was to examine perinatal risk factors for childhood Type 1 diabetes
Abstract:
AIMS: To investigate perinatal risk factors for childhood Type 1 diabetes in a UK population cohort. METHODS: Perinatal data have been routinely recorded in Northern Ireland for all births in the period 1971-86 (n = 447 663). Diabetes status at the age of 15 years was ascertained in this cohort by identifying 991 children from 1079 registered with Type 1 diabetes diagnosed from 1971 to more...
International Classification:
Endocrine, nutritional and metabolic diseases - Diabetes mellitus - type 1 diabetes mellitus
Categories:
type 1 diabetes
Geography:
the United Kingdom
Diabet Med,
Vol: 22 Page: 200-6 February 2005
C. R. Cardwell; D. J. Carson; C. C. Patterson
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The aim of this study was to examine the validity of parental recall of birthweight.
Abstract:
Recent evidence suggests potential associations between birthweight and disease in later life. For resource or other reasons recorded birthweight may be unavailable to researchers who have access to uniquely relevant outcome data. The present study examined the validity of parental recall of birthweight. Parents of 1015 males and females aged 12 and 15 years participating in the Young more...
International Classification:
Other - parental recall
Categories:
recall of birthweigh
Geography:
Northern Ireland
Eur J Epidemiol,
Vol: 16 Page: 793-6 2000
K. A. Walton; L. J. Murray; A. M. Gallagher; G. W. Cran; M. J. Savage; C. Boreham
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The aim of this study was to explore the impact on mortality and morbidity of parenteral penicillin given to children before admission to hospital with suspected meningococcal disease
Abstract:
OBJECTIVE: To explore the impact on mortality and morbidity of parenteral penicillin given to children before admission to hospital with suspected meningococcal disease. DESIGN: Retrospective comparison of fatal and non-fatal cases. SETTING: England, Wales, and Northern Ireland; December 1997 to February 1999. PARTICIPANTS: 158 children aged 0-16 years (26 died, 132 survived) in whom a more...
International Classification:
Other - parenteral penicillin
Categories:
parenteral penicillin; -mortality; morbidity;
Geography:
the United Kingdom
Bmj,
Vol: 332 Page: 1295-8 June 2006
A. Harnden; N. Ninis; M. Thompson; R. Perera; M. Levin; D. Mant; R. Mayon-White
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The aim of this study was to whether histopathological examination of the placenta in cases of neonatal encephalopathy could identify significant antenatal processes that are not recognized by clinical assessment alone
Abstract:
Neonatal encephalopathy (NE) remains an important cause of morbidity and mortality in the term infant, and many cases have an antepartum, rather than an intrapartum, etiology. Chronic processes such as thrombosis result in changes in the placenta. We sought to determine whether histopathological examination of the placenta in cases of NE, focusing on these changes, could identify more...
International Classification:
Pregnancy, childbirth and the puerperium - neonatal encephalopathy
Categories:
antenatal processes; placenta; - neonatal encephalopathy
Geography:
Republic of Ireland
Hum Pathol,
Vol: 35 Page: 875-80 July 2004
D. G. McDonald; P. Kelehan; J. B. McMenamin; W. A. Gorman; D. Madden; I. N. Tobbia; E. E. Mooney
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The aim of this study was to examine the prevalence, clinical characteristics, management and changes in survival over time of vertically HIV-infected infants developing PCP and/or CMV infection
Abstract:
OBJECTIVES: The outcome of Pneumocystis carinii pneumonia (PCP) in HIV-infected infants is poor, and the role of cytomegalovirus (CMV) co-infection in the course and outcome of PCP is unclear. This study describes the prevalence, clinical characteristics, management and changes in survival over time of vertically HIV-infected infants developing PCP and/or CMV infection. METHODS: Data on more...
International Classification:
Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV
Categories:
HIV-infected
Geography:
Republic of Ireland and the United Kingdom
Aids,
Vol: 15 Page: 335-9 February 2001
A. J. Williams; T. Duong; L. M. McNally; P. A. Tookey; J. Masters; R. Miller; E. G. Lyall; D. M. Gibb
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The aim of this study was to examine polymorphisms within the vitamin B12 dependent methylmalonyl-coA mutase are not risk factors for neural tube defects
Abstract:
Methionine synthase and methylmalonyl-CoA mutase (mutase) are the only two known vitamin B(12) (B(12)) dependent enzymes in humans. A lower level of B(12) has been shown to be an independent maternal risk factor for neural tube defects (NTDs) prompting an investigation of common genetic variants within B(12) dependent enzymes. To investigate the role of methylmalonyl-CoA mutase variants more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - neural tube defects - condiction
Categories:
vitamin B12 dependent methylmalonyl-coA mutase; -neural tube defects
Geography:
Republic of Ireland
Mol Genet Metab,
Vol: 80 Page: 463-8 December 2003
A. Parle-McDermott; E. J. McManus; J. L. Mills; V. B. O'Leary; F. Pangilinan; C. Cox; A. Weiler; A. M. Molloy; M. Conley; D. Watson; J. M. Scott; L. C. Brody; P. N. Kirke
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This study describes features associated with the presentation of posterior fossa tumours in childhood
Abstract:
A retrospective review was performed of the age profile and clinical features at presentation of 79 children with posterior fossa tumours. The mean age at presentation in this series (6.6 years) is consistent with a decreasing trend over the past 70 years. Headaches, ataxia and torticollis emerge as significant symptoms worthy of further investigation whilst abdominal pain and more...
International Classification:
Neoplasms - Malignant neoplasms - posterior fossa tumours
Categories:
posterior fossa tumours
Geography:
Republic of Ireland
Ir Med J,
Vol: 94 Page: 52-3 February 2001
D. F. O'Brien; J. Caird; M. Kennedy; G. A. Roberts; J. C. Marks; D. A. Allcutt
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The aim of this study was to examine if predictive values of high risk markers Apgar, acidosis and others - would be increased if early continuous electroencephalographic monitoring allowed accurate identification of all neonatal seizures
Abstract:
BACKGROUND: After perinatal asphyxia, predicting which infants will develop significant hypoxic-ischemic encephalopathy and neonatal seizures remains a difficult task. High-risk markers (Apgar score, acidosis, nucleated red blood cells, and resuscitation) have been used to predict neonatal seizures with varying success. The "3 strikes" of Apgar score of <5 at 5 minutes, pH more...
International Classification:
Neonatal seizures
Categories:
neonatal seizures; encephalopathy
Geography:
Republic of Ireland
Pediatrics,
Vol: 118 Page: 41-6 July 2006
D. M. Murray; C. A. Ryan; G. B. Boylan; A. P. Fitzgerald; S. Connolly
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The aim of this study was to quantify the risk of adverse perinatal outcomes birth defects and pregnancy complications following assisted reproductive technology
Abstract:
BACKGROUND: Increasing use of fertility therapy has elicited concerns regarding adverse effects for expectant mothers and the health of children thus conceived. AIMS: To study the risk of adverse perinatal outcomes, birth defects and pregnancy complications following assisted reproductive technology (ART). METHODS: Questionnaire-based study involving 1,524 children and 1,182 pregnancies more...
International Classification:
Pregnancy, childbirth and the puerperium
Categories:
assisted reproductive technology
Geography:
International
Ir J Med Sci,
Vol: 177 Page: 233-41 September 2008
C. Allen; S. Bowdin; R. F. Harrison; A. G. Sutcliffe; L. Brueton; G. Kirby; J. Kirkman-Brown; C. Barrett; W. Reardon; E. Maher
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This article discusses some of the difficulties facing nurses involved in the care of critically ill children and reviews the literature on pressure ulcer assessment, highlighting the lack of a universal tool for risk assessment in this area
Abstract:
Nursing staff in paediatric intensive care units (PICUs) regularly face a complex combination of nursing problems when admitting critically ill children. The assessment of skin integrity might not always be a priority during the initial period following admission. This article outlines some of the difficulties facing nurses involved in the care of critically ill children and reviews the more...
Geography:
Northern Ireland
Nurs Stand,
Vol: 17 Page: 71-4, 76 October 2002
V. Murdoch
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The aim of this study was to determine the prevalence of overweight and obesity in Irish children using four different weight-for-height methods and to examine secular trends from previous national data
Abstract:
OBJECTIVE: To determine the prevalence of overweight and obesity in Irish children using four different weight-for-height methods and to examine secular trends from previous national data. DESIGN: A cross-sectional survey. Weight and height were measured according to standard procedures and used to determine the prevalence of overweight and obesity using four weight-for-height methods more...
International Classification:
Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - obesity
Categories:
overweight; obesity
Geography:
Republic of Ireland
Eur J Clin Nutr,
Vol: 61 Page: 743-51 June 2007
J. L. O'Neill; S. N. McCarthy; S. J. Burke; E. M. Hannon; M. Kiely; A. Flynn; M. A. Flynn; M. J. Gibney
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The aim of this study was to describe psychological distress and the asylum process
Abstract:
Although asylum seeking has become a major political issue in the Western world, research on its psychological impact is still in its infancy. This study examined levels and predictors of distress among a community sample of persons who have sought asylum in Ireland. A key aim was to provide a longitudinal analysis of the relationship between legal status security and psychological more...
International Classification:
Symptoms and signs involving the circulatory and respiratory system - Symptoms and signs involving the circulatory and respiratory systems - epistaxis
Categories:
psychological distress; the asylum process
Geography:
Republic of Ireland
J Nerv Ment Dis,
Vol: 196 Page: 37-45 January 2008
D. A. Ryan; C. A. Benson; B. A. Dooley
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The aim of the study was to compare the potential protective effect for the decrease in platelet count associated with RATG therapy against pediatric renal transplant graft vascular thrombosis
Abstract:
Graft thrombosis is a serious complication in pediatric renal transplantation. We assess a potential protective effect for the decrease in platelet count associated with RATG therapy against pediatric renal transplant graft vascular thrombosis. Between January 1986 and December 1998, 120 kidney transplants were performed in 95 pediatric recipients. Patients were divided into two groups. more...
International Classification:
Organ transplants
Categories:
renal transplant graft vascular thrombosis
Geography:
Republic of Ireland
Pediatr Transplant,
Vol: 10 Page: 816-21 November 2006
M. H. Kamel; P. Mohan; P. J. Conlon; D. M. Little; P. O'Kelly; D. P. Hickey
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The aim of this study was to examine the recurrence rate of macrosomia in non-diabetic pregnancy and to see if the history of multiple prior macrosomic infants confers additional risk
Abstract:
Fetal macrosomia (birth weight >/=4,500 g) is known to increase a number of adverse maternal and perinatal outcomes. Although there is a clear association between maternal diabetes mellitus and fetal macrosomia, the majority of macrosomic infants are born to non-diabetic mothers. We wished to determine the recurrence rate of macrosomia in non-diabetic pregnancy and to see if a history more...
International Classification:
Pregnancy, childbirth and the puerperium
Categories:
macrosomia in non-diabetic pregnancy; macrosomic infants
Geography:
Republic of Ireland
J Obstet Gynaecol,
Vol: 27 Page: 374-8 May 2007
C. A. Walsh; R. T. Mahony; M. E. Foley; L. Daly; C. O'Herlihy
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This study examined relationships between the longitudinal development of biological risk factors for coronary heart disease and the development of lifestyles considered to be atherogenic
Abstract:
The purpose of this study was to examine relationships between the longitudinal development of biological risk factors for coronary heart disease (CHD) (namely, serum lipids, body fatness, blood pressure and cardiorespiratory fitness) and the development of lifestyles considered to be atherogenic. The study was conducted in a representative sample of adolescents from Northern Ireland, a more...
International Classification:
Longitudinal - Coronary heart disease
Categories:
coronary heart disease
Geography:
Northern Ireland
Public Health,
Vol: 113 Page: 7-12 January 1999
C. Boreham; J. Twisk; W. van Mechelen; M. Savage; J. Strain; G. Cran
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This paper discusses the knowledge and skills required for effective management and improved outcomes for children with renal anemia
Geography:
Republic of Ireland
Paediatr Nurs,
Vol: 14 Page: 24-7 September 2002
L. Ennis
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This study evaluated the incidence of renal damage in a large series of male infants with high grade vesicoureteral reflux diagnosed after the first urinary tract infection
Abstract:
PURPOSE: Vesicoureteral reflux during infancy is found mainly in males, and it is of high grade and often bilateral. The higher predominance of male infants is reported in series when the reflux is diagnosed prenatally and when it is detected after urinary tract infection. Renal parenchymal damage may already be present at birth before any episode of urinary tract infection or acquired more...
International Classification:
Diseases of the genitourinary system - Other diseases of urinary system-urinary tract infection
Categories:
urinary tract infection
Geography:
Republic of Ireland
J Urol,
Vol: 168 Page: 1708-10; discussion 1710 October 2002
S. Cascio; B. Chertin; E. Colhoun; P. Puri
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The aim of this study was to investigate the epidemiology of spinal cord injury in Ireland over 1 year
Abstract:
STUDY DESIGN: Prospective data collection on all patients with spinal cord injury (SCI) admitted for a comprehensive management programme. OBJECTIVES: To examine the epidemiology of SCI in Ireland over 1 year. SETTING: Ireland's National Spinal Cord Injury Centre. METHODS: Systematic data collection on all patients admitted with SCI for management. RESULTS: A total of 46 patients (40 more...
International Classification:
Injury, poisoning and certain other consequences of external causes - injury
Categories:
spinal cord injury
Geography:
Republic of Ireland
Spinal Cord,
Vol: 44 Page: 445-8 July 2006
R. J. O'Connor; P. C. Murray
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The aim of this study was to examine if sharing a bed or bedroom with an infected family member is an important risk factor for primary childhood H. pylori infection.
Abstract:
BACKGROUND: The exact mode of transmission of Helicobacter pylori is yet to be established. Close personal contact among family members appears to be a key factor. The aim of this study was to establish whether sharing a bed or bedroom with an infected family member is an important risk factor for primary childhood H. pylori infection. METHODS: Fifty-two families with at least 1 child more...
International Classification:
Bacterium - Helicobacter pylori
Categories:
H. pylori infection.
Geography:
Northern Ireland
Pediatr Infect Dis J,
Vol: 24 Page: 149-52 February 2005
S. Farrell; G. M. Doherty; I. Milliken; M. D. Shield; W. A. McCallion
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This article discusses environmental risk factors for schizophrenia including prenatal infection, obstetric complications, childhood developmental impairments etc
Abstract:
This paper gives an overview of environmental risk factors for schizophrenia. The presence of certain biological and psychosocial factors at certain points in the lifespan has been linked to later development of schizophrenia. These include prenatal infection, obstetric complications, childhood developmental impairments, early rearing environment, adolescent cannabis use, urban dwelling more...
Geography:
Republic of Ireland
Schizophr Res,
Vol: 79 Page: 5-13 November 2005
M. Cannon; M. C. Clarke
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The aim of this study was to examine the risk of serious neurologic disease after immunization in early childhood
Abstract:
OBJECTIVE: We sought to investigate the risk of serious neurologic disease after immunization in early childhood. METHODS: The results of a 3-year prospective study of children (2-35 months old) in Britain and Ireland with encephalitis and/or severe illness with convulsions and fever were linked to each child's vaccine history. Cases were reported via the British Paediatric Surveillance more...
International Classification:
Vaccination
Categories:
serious neurologic disease after immunization
Geography:
Republic of Ireland and the United Kingdom
Pediatrics,
Vol: 120 Page: 314-21 August 2007
K. N. Ward; N. J. Bryant; N. J. Andrews; J. S. Bowley; A. Ohrling; C. M. Verity; E. M. Ross; E. Miller
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This aim of this study was to screen for a new MTHFR polymorphisms and neural tube defect risk
Abstract:
The enzyme, 5,10-methylenetetrahydrofolate reductase (MTHFR) plays a key role in cellular folate metabolism. The A222V (677C->T) polymorphism is a confirmed neural tube defect (NTD) risk factor within Irish and other populations. To search for other unknown single nucleotide polymorphisms (SNPs) that might play a role in the etiology of NTDs, we examined the entire MTHFR coding region more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - neural tube defects - condiction
Categories:
polymorphisms; neural tube defect
Geography:
Republic of Ireland
Am J Med Genet A,
Vol: 138A Page: 99-106 October 2005
V. B. O'Leary; J. L. Mills; A. Parle-McDermott; F. Pangilinan; A. M. Molloy; C. Cox; A. Weiler; M. Conley; P. N. Kirke; J. M. Scott; L. C. Brody
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The aim of this study was to examine trends in the incidence of Type 1 diabetes in Northern Ireland over the period 1989-2003
Abstract:
AIMS: To investigate secular trends in the incidence of Type 1 diabetes in Northern Ireland over the period 1989-2003. To highlight geographical variations in the incidence of Type 1 diabetes by producing disease maps and to compare incidence rates by relevant area characteristics. METHODS: New cases of Type 1 diabetes in children aged 0-14 years in Northern Ireland were prospectively more...
International Classification:
Endocrine, nutritional and metabolic diseases - Diabetes mellitus - type 1 diabetes mellitus
Categories:
type 1 diabetes
Geography:
Northern Ireland
Diabet Med,
Vol: 24 Page: 289-95 March 2007
C. R. Cardwell; D. J. Carson; C. C. Patterson
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The aim of this study was to describe polymorphisms in HTR(1B) and HTR(2A) in a European attention-deficit hyperactivity disorder sample
Abstract:
Attention deficit hyperactivity disorder (ADHD) is a highly heritable and heterogeneous disorder, which usually becomes apparent during the first few years of childhood. Imbalance in dopamine neurotransmission has been suggested as a factor predisposing to ADHD. However, evidence has suggested an interaction between dopamine and serotonin systems in the pathophysiology of the disorder. more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
Republic of Ireland and the United Kingdom
Mol Psychiatry,
Vol: 7 Page: 718-25 2002
Z. Hawi; M. Dring; A. Kirley; D. Foley; L. Kent; N. Craddock; P. Asherson; S. Curran; A. Gould; S. Richards; D. Lawson; H. Pay; D. Turic; K. Langley; M. Owen; M. O'Donovan; A. Thapar; M. Fitzgerald; M. Gill
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The aim of this study was to investigate if serum albumin concentrations in Down Syndrome were lower than those of a cohort of similarly moderately- to-severely-disabled institutionalised patients without Down Syndrome
Abstract:
AIMS: We investigated whether or not serum albumin concentrations in Down Syndrome were lower than those of a cohort of similarly moderately- to-severely-disabled institutionalised patients without Down Syndrome and, if so, whether or not this could be ascribed to the presence of liver disease. We also sought to determine the influence of Down Syndrome, age, liver disease, and more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Chromosomal abnormalities, not elsewhere classified - Down Syndrome
Categories:
serum albumin concentrations; -Down Syndrome
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 174 Page: 4-8 2005 Apr-Jun
C. S. Clarke; F. J. Bannon
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The aim of this study was examine risk factors - of which smoking was identified - for sudden infant death syndrome in Irish Infants
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
smoking; -sudden infant death syndrome
Geography:
Republic of Ireland
Ir Med J,
Vol: 95 Page: 111-3 April 2002
M. McDonnell; M. Mehanni; C. McGarvey; M. Oregan; T. G. Matthews
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The aim of this study was to test for socioeconomic differences in some biological and behavioural risk factors for obesity in a representative and contemporary sample of adolescents
Abstract:
OBJECTIVES. To test for socioeconomic differences in some biological and behavioral risk factors for obesity in a representative and contemporary sample of adolescents. METHODS: Cohort study of 2 016 randomly selected 12- and 15-year-olds representative of Northern Ireland, studied in 2000. We tested for differences in obesity risk factors based on a priori hypotheses between more...
International Classification:
Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - obesity
Categories:
obesity
Geography:
Northern Ireland
Int J Pediatr Obes,
Vol: 1 Page: 114-9 2006
M. Mutunga; A. M. Gallagher; C. Boreham; D. C. Watkins; L. J. Murray; G. Cran; J. J. Reilly
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This study examined socioeconomic differentials in behavioural and biological risk factors for coronary heart disease in young people from Northern Ireland, taking into account differences in biological maturation
Abstract:
BACKGROUND: This study investigates the existence of socioeconomic differentials in behavioural and biological risk factors for coronary heart disease in young people from Northern Ireland, taking into account differences in biological maturation. METHODS: A school-based prospective study, with measurements in 1989/1990 and 1992/1993. Socio-economic position was based on occupational more...
International Classification:
Longitudinal - coronary heart disease
Categories:
coronary heart disease
Geography:
Northern Ireland
Eur J Public Health,
Vol: 11 Page: 43-50 March 2001
F. J. Van Lenthe; C. A. Boreham; J. W. Twisk; J. J. Strain; J. M. Savage; G. D. Smith
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The aim of the review was to identify randomised controlled trials and controlled intervention studies that evaluated the effectiveness of preventive strategies in adolescent sport and to draw conclusions on the strength of the evidence
Abstract:
This systematic review set out to identify randomised controlled trials and controlled intervention studies that evaluated the effectiveness of preventive strategies in adolescent sport and to draw conclusions on the strength of the evidence. A literature search in seven databases (Medline, SportDiscus, EMBASE, CINAHL, PEDro, Cochrane Review and DARE) was carried out using four more...
International Classification:
Systematic Review
Categories:
effectiveness of preventive strategies in adolescent sport
Geography:
Northern Ireland
Br J Sports Med,
Vol: 41 Page: 627-38 October 2007
L. Abernethy; C. Bleakley
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The aim of this study was to examine young people no longer attending mainstream school and risk for problem drug use compared with their peers in mainstream education.
Abstract:
Twenty-nine young people aged 12–13 years considered to be at a high risk of substance abuse primarily because they no longer attend mainstream school participated in the study by completing a questionnaire designed to obtain information on their drug-using behaviours. The evidence in this paper suggests that many of them are already at a high risk for problem drug use compared more...
International Classification:
Drugs - problem use
Categories:
problem drug use
Geography:
Northern Ireland
Child Care in Practice,
Vol: 11 Page: 313-321 2005
Patrick McCrystal; Kathryn Higgins; Andrew Percy
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This article discusses Sudden Infant Death Syndrome and circulatory control
Abstract:
The majority of Sudden Infant Death Syndrome (SIDS) infants die during sleep and especially during the overnight sleep period. Recent evidence from SIDS cases, which occurred while on a cardiorespiratory monitor at home, has suggested that the mechanism of death involves circulatory failure, with the development of a shock like state, associated with a progressive bradycardia in the more...
Geography:
Republic of Ireland
Child Care Health Dev,
Vol: 28 Suppl 1 Page: 41-3 September 2002
T. Matthews
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The aim of this study was to assess if Irish parents follow the currently recommended childcare guidelines to reduce the risk of Sudden Infant Death Syndrome and to examine factors that may have an impact on their acceptance
Abstract:
BACKGROUND: Factors that place an infant at increased risk of sudden infant death include the prone sleep position, overheating and parental smoking, while practices such as bottle-feeding, co-sleeping and the use of pacifiers remain controversial. Major publicity campaigns have been undertaken, which have included the distribution of printed material and extensive media coverage. AIMS: more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
sudden infant death syndrome guidelines;
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 169 Page: 40-3 2000 Jan-Mar
A. Cullen; B. Kiberd; M. McDonnell; M. Mehanni; T. G. Matthews; M. O'Regan
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The aim of this study was to determine the frequency of reported suicidal thoughts and acts in (a) a school-based sample of Irish adolescents, and (b) in adolescents attending a community child and family mental health service.
Abstract:
Suicide and attempted suicide are now major public health problems in Ireland. It is observed that little is known about the mental health needs of Irish young people. Suicidal acts, depressive disorders and social exclusion are known to be risk factors for future suicide but few young people with these risk factors are in contact with medical or mental health services. The aim of the more...
International Classification:
External causes of morbidity and mortality - Intentional self-harm - suicidal
Categories:
suicidal thoughts
Geography:
Republic of Ireland
Irish Journal of Psychological Medicine,
Vol: 18 Page: 82-86 2001
Jo Rowley; Kathleen Ganter; Carol Fitzpatrick
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The aim of this study was to examine the prevalence of toxoplasma susceptibility in pregnant women
Abstract:
Congenital toxoplasmosis (CT) arises as a result of new acquisition of Toxoplasma infection by a susceptible woman during pregnancy. Early detection of CT through neonatal screening programmes could optimize management and improve infant outcome. This study sought to estimate the prevalence of Toxoplasma susceptibility in pregnant women. As detection of Toxoplasma antibodies in neonatal more...
International Classification:
Other - toxoplasma
Categories:
toxoplasma susceptibility
Geography:
Republic of Ireland
Ir Med J,
Vol: 101 Page: 220-1 2008 Jul-Aug
W. Ferguson; P. D. Mayne; B. Lennon; K. Butler; M. Cafferkey
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The aim of this study was to describe the association of SNAP-25/DdeI allelel and attention-deficit hyperactivity disorder cases
Abstract:
Several lines of evidence have suggested that ADHD is a polygenic disorder produced by the interaction of several genes each of a minor effect. Synaptosomal-associated protein 25 (SNAP-25) is a presynaptic plasma membrane protein which is expressed highly and specifically in the nerve cells. The gene encodes a protein essential for synaptic vesicle fusion and neurotransmitter release. more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
Republic of Ireland
Mol Psychiatry,
Vol: 7 Page: 913-7 2002
K. Brophy; Z. Hawi; A. Kirley; M. Fitzgerald; M. Gill
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The aim of this study was to examine the relationship between toddlers height and increased risk for scalds
International Classification:
Injury, poisoning and certain other consequences of external causes - injury
Categories:
scalds
Geography:
Republic of Ireland
Burns,
Vol: 30 Page: 581-2 September 2004
S. M. Murphy; D. Murray; K. Rooney; D. J. Orr
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The aim of this study was to examine fibre intake and the incidence of constipation in Irish children aged 5-8 years
Abstract:
Despite its health implications, the fibre intake of Irish children is unknown. The North/South Ireland Food Consumption Survey indicated that 77% of Irish adults do not consume adequate fibre and surveys of children and adolescents in Canada and Sweden have confirmed suboptimal fibre intake in these groups. This study undertook to assess fibre intake and the incidence of constipation more...
International Classification:
Diet and lifestyle
Categories:
fibre intake; constipation
Geography:
Republic of Ireland
Ir Med J,
Vol: 101 Page: 118-20 April 2008
L. M. Glackin; M. Fraser; O. Neill MB
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The aim of this study was to examine the spending pattern of money by young people, and its important when investigating drug use during adolescence
Abstract:
It is now common for young people in full-time compulsory education to hold part-time jobs. However, while the 1990s experienced a rise in illicit drug use particularly among young people and an increase in the level of interest in identifying factors associated with drug use, little attention has been paid to the influence of the money young people have to spend and its potential links more...
International Classification:
Drugs - investigating use
Categories:
investigating drug use
Geography:
Northern Ireland
Drugs: Education, Prevention & Policy,
Vol: 14 Page: 19-28 2007
Patrick McCrystal; Andrew Percy; Kathryn Higgins
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The aim of this study was to examine the epidemiological factors associated with Sudden Infant Death Syndrome to give a general profile of SID cases occurring in Ireland between the years 1993 to 1997
Abstract:
This paper examines some epidemiological factors associated with SIDS to give a general profile of SIDS cases occurring in Ireland between the years 1993 to 1997. There has been a dramatic decrease in the incidence of the Sudden Infant Death Syndrome (SIDS) in the Republic of Ireland in the last decade from an average rate of 2.2/1000 live-births in the 1980s to 0.8/1000 live-births in more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
sudden infant death syndrome
Geography:
Republic of Ireland
Ir Med J,
Vol: 93 Page: 264-8 December 2000
M. Mehanni; A. Cullen; B. Kiberd; M. McDonnell; M. O'Regan; T. Matthews
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The article discusses how to turn research into effective obesity prevention strategies - a clearer understanding of the psycho-social, behavioural and environmental factors that influence activity is needed
Abstract:
With the increasing prevalence of childhood obesity, there is an urgent need to identify risk factors that are amenable to preventative action. However, there is a remarkable lack of consistency between studies that have investigated the relationships between measurements of physical activity and energy expenditure and body fatness in children. This disparity could be because energy more...
Geography:
Northern Ireland
Proc Nutr Soc,
Vol: 65 Page: 393-402 November 2006
K. L. Rennie; J. C. Wells; T. A. McCaffrey; M. B. Livingstone
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