Irish Child Health Database - Peer Reviewed Papers
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1. Gene expression of fibroblast growth factors 10 and 7 is downregulated in the lung of nitrofen-induced diaphragmatic hernia in rats
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2. Gene expression of insulin-like growth factor-1 and epidermal growth factor is downregulated in the heart of rats with nitrofen-induced diaphragmatic hernia
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3. Glutathione S-transferase: a potential new marker of intestinal ischemia
The aim of this study was to determine if Glutathione S-transferase levels correlated with histologic changes of intestinal ischemia in a controlled animal model of mesenteric intestinal ischemia
J Pediatr Surg, Vol: 37 Page: 1543-8 November 2002
S. Khurana; M. T. Corbally; F. Manning; T. Armenise; B. Kierce; C. Kilty -
4. Helicobacter pylori infection of human and murine primary gastric cells
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5. High mineral and vitamin E intake by pregnant ewes lowers colostral immunoglobulin G absorption by the lamb
The aim of this study was to evaluate the effects of supplementing pregnant ewe's diet with high levels of minerals and vitamin E on immunoglobulin G absorption by the lamb and if any altered efficacy of IgG absorption was due to colostrum or the lamb
J Anim Sci, Vol: 83 Page: 871-8 April 2005
T. M. Boland; N. Keane; P. Nowakowski; P. O. Brophy; T. F. Crosby -
6. History of surfactant from 1980
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7. Host cell tropism underlies species restriction of human and bovine Cryptosporidium parvum genotypes
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8. Human seroprevalence to Coxiella burnetii (Q fever) in Northern Ireland
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9. Impaired alveolar epithelial cell differentiation in the hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia
The aim of this study was to investigate molecular markers for AECs-I [ICAM-1, T1alpha, aquaporin 5 ] and molecular markers for AECs-II [thyroid transcription factor-1), surfactant protein in the nitrofen-induced congenital diaphragmatic hernia lung
Pediatr Surg Int, Vol: 23 Page: 405-10 May 2007
H. Takayasu; N. Nakazawa; S. Montedonico; K. Sugimoto; H. Sato; P. Puri -
10. Increased expression of ICAM-1 and VCAM-1 in the lung of nitrofen-induced congenital diaphragmatic hernia in rats
The aim of this study was to investigate pulmonary ICAM-1 and VCAM-1 expression in congenital diaphragmatic hernia lung in rats and to determine the effect of antenatal glucocorticoid
Pediatr Surg Int, Vol: 19 Page: 365-70 July 2003
K. Unemoto; M. Sakai; H. Shima; N. Guarino; P. Puri -
11. Increased fibronectin expression in developing embryos is associated with abnormal notochord in the Adriamycin rat model
The aim of this study was to examine the hypothesis that adriamycin administration could promote upregulation of FN expression increasing gut-notochord adherence and development of abnormal ventral notochordal branching in the Adriamycin rat model
Pediatr Surg Int, Vol: 20 Page: 276-82 April 2004
A. Mortell; A. M. O'Donnell; S. Giles; J. Bannigan; P. Puri -
12. Increased vascular endothelial growth factor peptide and gene expression in hypoplastic lung in nitrofen induced congenital diaphragmatic hernia in rats
The aim of this study was to investigate mRNA and protein levels of vascular endothelial growth factor in congenital diaphragmatic hernia lung and to determine whether antenatal Dex treatment has any effect Vascular endothelial growth factor production
Pediatr Surg Int, Vol: 18 Page: 221-6 May 2002
T. Oue; A. Yoneda; H. Shima; Y. Taira; P. Puri -
13. Induction of inflammatory cytokines in the brain following respiratory infection with Bordetella pertussis
The aim of this study was to describe Bordetella pertussis respiratory infection, its expression of mRNA transcripts for IL-1beta and TNFalpha and transient expression of IL-6 in the hippocampus and hypothalamus
J Neuroimmunol, Vol: 102 Page: 172-81 January 2000
C. E. Loscher; S. Donnelly; M. A. Lynch; K. H. Mills -
14. Interaction of Cryptosporidium hominis and Cryptosporidium parvum with primary human and bovine intestinal cells
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15. Is nutrition an aetiological factor for inflammatory bowel disease?
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16. Key apoptosis regulating proteins are down-regulated during postnatal tissue development
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17. Kidney development in the nitrofen-induced pulmonary hypoplasia and congenital diaphragmatic hernia in rats
The aims of this study were to investigate the effects of pulmonary hypoplasia on renal development and to evaluate retinoids status of kidneys in the nitrofen model of congenital diaphragmatic hernia
J Pediatr Surg, Vol: 42 Page: 239-43 January 2007
S. Montedonico; N. Nakazawa; T. Shinkai; J. Bannigan; P. Puri -
18. Linkage mapping of the locus for inherited ovine arthrogryposis (IOA) to sheep chromosome 5
The aim of this study was to undertake a genome scan using 187 microsatellite genetic markers and all backcross animals were phenotyped at birth for the presence and severity of arthrogryposis
Mamm Genome, Vol: 18 Page: 43-52 January 2007
A. M. Murphy; D. E. MacHugh; S. D. Park; E. Scraggs; C. S. Haley; D. J. Lynn; M. P. Boland; M. L. Doherty -
19. Low incidence of concurrent enteric infection associated with sporadic and outbreak-related human cryptosporidiosis in Northern Ireland
The aim of this study was to examine the frequency of mixed enteric infections with C.parvum and to determine the coinfecting organism in both sporadic and outbreak-related cryptosporidiosis
J Clin Microbiol, Vol: 40 Page: 3107-8 August 2002
J. E. Moore; L. Crothers; B. C. Millar; E. Crothers; P. J. Rooney; L. Xiao; J. S. Dooley; C. J. Lowery -
20. Low risk of inhibitor formation in haemophilia patients after a change in treatment from Chinese hamster ovary cell-produced to baby hamster kidney cell-produced recombinant factor VIII
This study examined the low risk of inhibitor formation in haemophilia patients after a change in treatment from Chinese hamster ovary cell-produced to baby hamster kidney cell-produced recombinant factor VIII
Thromb Haemost, Vol: 98 Page: 1188-92 December 2007
E. Singleton; J. Smith; M. Kavanagh; B. Nolan; B. White -
21. Lower filamentation rates of Candida dubliniensis contribute to its lower virulence in comparison with Candida albicans
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22. Mammalian sleep
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23. Management of anticoagulation and its reversal during paediatric cardiopulmonary bypass: a review of current UK practice
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24. Methylphenidate: a review of its neuropharmacological, neuropsychological and adverse clinical effects
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25. Modulation of immune cell function by polyunsaturated fatty acids
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26. Molecular genotyping of human cryptosporidiosis in Northern Ireland: epidemiological aspects and review
The aim of this study was to examine the genotype of C. parvum oocysts isolated from human faeces in sporadic cases of cryptosporidiosis in Northern Ireland
Ir J Med Sci, Vol: 170 Page: 246-50 2001 Oct-Dec
C. J. Lowery; B. C. Millar; J. E. Moore; J. Xu; L. Xiao; P. J. Rooney; L. Crothers; J. S. Dooley -
27. Multiple gastrointestinal atresias result from disturbed morphogenesis
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28. New hypothesis on the pathogenesis of ileocecal intussusception
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29. Non-multifactorial neural tube defects
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30. Notable sequential alterations in notochord volume during development in the Adriamycin rat model
The aim of this study was to assess notochord volume sequentially from gestational days 10 to 14 to test the hypothesis that notochord hypertrophy occurs maximally soon after Adriamycin administration
J Pediatr Surg, Vol: 40 Page: 403-6 February 2005
A. Mortell; J. Gillick; S. Giles; J. Bannigan; P. Puri -
31. Notochord anomalies in the adriamycin rat model: A morphologic and molecular basis for the VACTERL association
The aim of this study was to test the hypothesize that notochord anomalies allow ectopic expression of molecular signals in the developing embryo and thus lead to VACTERL malformations
J Pediatr Surg, Vol: 38 Page: 469-73; discussion 469-73 March 2003
J. Gillick; E. Mooney; S. Giles; J. Bannigan; P. Puri -
32. Ocular toxocariasis in schoolchildren
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33. Ocular wounding prevents pre-retinal neovascularization and upregulates PEDF expression in the inner retina
The aim of this study was to investigate a possible anti-angiogenic effect of penetrating ocular injury in a murine model of oxygen induced proliferative retinopathy (OIR) and determined if such a procedure alters PEDF expression in the retina
Mol Vis, Vol: 10 Page: 432-8 June 2004
A. W. Stitt; D. Graham; T. A. Gardiner -
34. Pathogenesis of Hirschsprung's disease and its variants: recent progress
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35. Patterns of milk and food intake in infants from birth to age 36 months: the Euro-growth study
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36. Postnatal development of the mucosal plexus in the porcine small and large intestine
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37. Prenatal and postnatal neuromuscular development of the ureterovesical junction
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38. Prepubertal unilateral spermatic vessel ligation decreases haploid cell population of ipsilateral testis postpubertally in rats
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39. Prevalence of gastrointestinal bacterial pathogens in a population of zoo animals
The aim of this study was to the prevalence of gastrointestinal bacterial pathogens - Campylobacter, Escherichia coli O157:H7, Salmonella, Shigella, Yersinia, Arcobacter
Zoonoses Public Health, Vol: 55 Page: 166-72 April 2008
J. Stirling; M. Griffith; I. Blair; M. Cormican; J. S. Dooley; C. E. Goldsmith; S. G. Glover; A. Loughrey; C. J. Lowery; M. Matsuda; R. McClurg; K. McCorry; D. McDowell; A. McMahon; B. Cherie Millar; Y. Nagano; J. R. Rao; P. J. Rooney; M. Smyth; W. J. Snelling; J. Xu; J. E. Moore -
40. Protection against Bordetella pertussis in mice in the absence of detectable circulating antibody: implications for long-term immunity in children
The aim of this study was to examine the murine respiratory challenge model to demonstrate persistent vaccine-induced protection against Bordetella pertussis in the absence of circulating antibody at the time of challenge
J Infect Dis, Vol: 181 Page: 2087-91 June 2000
B. P. Mahon; M. T. Brady; K. H. Mills -
41. Rabbit antithymocyte globulin as induction immunotherapy for pediatric deceased donor kidney transplantation
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42. Rabbit antithymocyte globulin related decrease in platelet count reduced risk of pediatric renal transplant graft thrombosis
The aim of the study was to compare the potential protective effect for the decrease in platelet count associated with RATG therapy against pediatric renal transplant graft vascular thrombosis
Pediatr Transplant, Vol: 10 Page: 816-21 November 2006
M. H. Kamel; P. Mohan; P. J. Conlon; D. M. Little; P. O'Kelly; D. P. Hickey -
43. Random mutagenesis to identify novel Helicobacter mustelae virulence factors
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44. Reduced expression of aquaporin 5 water channel in nitrofen-induced hypoplastic lung with congenital diaphragmatic hernia rat model
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45. Regional differences in nitrergic neuronal density in the developing porcine urinary bladder
The aim of this study was to investigate the changes in density and morphology of the intramural nitrergic neurons of the porcine urinary bladder during development using whole-mount preparation
Pediatr Surg Int, Vol: 21 Page: 161-8 March 2005
M. E. Pirker; S. Montedonico; U. Rolle; H. Austvoll; P. Puri -
46. Reptile-associated Salmonellosis in residents in the South East of Ireland 2005 - 2007
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47. Retinoic acid rescues lung hypoplasia in nitrofen-induced hypoplastic foetal rat lung explants
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48. Selective chemical ablation of the enteric plexus in mice
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49. Structural immaturity of the heart in congenital diaphragmatic hernia in rats
The aim of this study was to evaluate the expression of important extracellular matrix components in rats heart with induced congenital diaphragm to test the hypothesis that an alteration of extracellular matrix may contribute to cardiac maldevelopment
J Pediatr Surg, Vol: 36 Page: 770-3 May 2001
N. Guarino; H. Shima; P. Puri -
50. Subtyping intimin genes from enteropathogenic Escherichia coli associated with outbreaks and sporadic cases in the United Kingdom and Eire
This study aimed to compare PCR-RFLP methods for subtyping the intimin gene from strains of typical and atypical enteropathogenic Escherichia coli and Verocytotoxin-producing E. coli
Mol Cell Probes, Vol: 17 Page: 149-56 August 2003
C. Jenkins; A. J. Lawson; T. Cheasty; G. A. Willshaw; P. Wright; G. Dougan; G. Frankel; H. R. Smith -
51. Surfactants: past, present and future


