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The aim of this study was to examine the incidence of type 2 diabetes in children <17 years of age and to investigate the relationship of diabetes with increasing childhood obesity in the U.K. and the Republic of Ireland (ROI)
Abstract:
OBJECTIVE: To estimate the incidence of type 2 diabetes in children <17 years of age and to investigate the relationship of diabetes with increasing childhood obesity in the U.K. and the Republic of Ireland (ROI). RESEARCH DESIGN AND METHODS: Active monthly reporting of cases by consultant pediatricians occurred through the framework of the British Pediatric Surveillance Unit, with more...
International Classification:
Endocrine, nutritional and metabolic diseases - Diabetes mellitus - type 2 diabetes mellitus
Categories:
type 2 diabetes; type 2 diabetes; obesity
Geography:
Republic of Ireland and the United Kingdom
Diabetes Care,
Vol: 30 Page: 1097-101 May 2007
L. Haines; K. C. Wan; R. Lynn; T. G. Barrett; J. P. Shield
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The aim of this study was to describe polymorphisms in HTR(1B) and HTR(2A) in a European attention-deficit hyperactivity disorder sample
Abstract:
Attention deficit hyperactivity disorder (ADHD) is a highly heritable and heterogeneous disorder, which usually becomes apparent during the first few years of childhood. Imbalance in dopamine neurotransmission has been suggested as a factor predisposing to ADHD. However, evidence has suggested an interaction between dopamine and serotonin systems in the pathophysiology of the disorder. more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
Republic of Ireland and the United Kingdom
Mol Psychiatry,
Vol: 7 Page: 718-25 2002
Z. Hawi; M. Dring; A. Kirley; D. Foley; L. Kent; N. Craddock; P. Asherson; S. Curran; A. Gould; S. Richards; D. Lawson; H. Pay; D. Turic; K. Langley; M. Owen; M. O'Donovan; A. Thapar; M. Fitzgerald; M. Gill
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The aim of this study was to examine the annual incidence of hospitalisations due to severe complications of varicella, describe the complications and estimate the annual mortality
Abstract:
AIMS: To estimate the annual incidence of hospitalisations due to severe complications of varicella, describe the complications and estimate annual mortality. METHODS: Active surveillance throughout the UK and Ireland for 13 months by paediatricians notifying cases to the British Paediatric Surveillance Unit and completing a questionnaire. The case definition was any child aged <16 more...
International Classification:
Certain infectious and parasitic diseases - Viral infections characterized by skin and mucous membrane lesions - varicella
Categories:
varicella
Geography:
Republic of Ireland and the United Kingdom
Arch Dis Child,
Vol: 92 Page: 1062-6 December 2007
J. C. Cameron; G. Allan; F. Johnston; A. Finn; P. T. Heath; R. Booy
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The aim of this study was to examine the severe food-allergic reactions in children across the UK and Ireland
Abstract:
AIM: Medical and lay concerns about food allergy are increasing. Whilst food allergy may be becoming more common, fatal reactions to food in childhood are very rare and their rate is not changing. We sought to establish how common severe reactions are. METHODS: Prospective survey, 1998 to 2000, of hospital admissions for food-allergic reactions-conducted primarily through the British more...
International Classification:
Diet and lifestyle
Categories:
severe food-allergic reactions
Geography:
Republic of Ireland and the United Kingdom
Acta Paediatr,
Vol: 94 Page: 689-95 June 2005
A. F. Colver; H. Nevantaus; C. F. Macdougall; A. J. Cant
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The aim of this study was to examine chronic granulomatous disease in the United Kingdom and Ireland
Abstract:
There are no epidemiological studies from the British Isles of chronic granulomatous disease, characterized by recurrent, life-threatening bacterial and fungal infections and inflammatory sequelae. Patients were enrolled in a national registry and medical records were analysed. Of 94 subjects, 69 had X-linked disease, 16 had autosomal recessive disease and nine were unknown. Prevalence more...
International Classification:
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - Other diseases of blood and blood-forming organs - Chronic granulomatous disease
Categories:
Chronic granulomatous disease
Geography:
Republic of Ireland and the United Kingdom
Clin Exp Immunol,
Vol: 152 Page: 211-8 May 2008
L. B. Jones; P. McGrogan; T. J. Flood; A. R. Gennery; L. Morton; A. Thrasher; D. Goldblatt; L. Parker; A. J. Cant
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The aim of this study was to examine the antimicrobial susceptibility profiles of clinical isolates of Streptococcus pneumoniae and S. pyogenes, isolated with particular reference to the new oral ketolide telithromycin and determine their distribution
Abstract:
OBJECTIVES: To investigate the antimicrobial susceptibility profiles of clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes, isolated from children within Great Britain and Ireland (Northern Ireland and Eire), with particular reference to the new oral ketolide telithromycin. To determine the distribution of macrolide resistance genes within the erythromycin more...
International Classification:
Bacterium - Streptococcus pneumoniae
Categories:
Streptococcus pneumoniae
Geography:
Republic of Ireland and the United Kingdom
J Infect,
Vol: 48 Page: 229-35 April 2004
J. Shackcloth; L. Williams; D. J. Farrell
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This study aimed to compare PCR-RFLP methods for subtyping the intimin gene from strains of typical and atypical enteropathogenic Escherichia coli and Verocytotoxin-producing E. coli
Abstract:
PCR-RFLP methods for subtyping the intimin gene from strains of typical and atypical enteropathogenic Escherichia coli (EPEC) and Verocytotoxin-producing E. coli (VTEC) were compared. A novel HhaI PCR-RFLP method was developed that was rapid, easy to use and amplified an 1852 bp fragment of the intimin gene from all isolates examined. This method was used to investigate the intimin more...
International Classification:
Effectiveness of measurement tool - PCR-RFLP subtyping methods
Categories:
PCR-RFLP subtyping methods; Escherichia coli
Geography:
Republic of Ireland and the United Kingdom
Mol Cell Probes,
Vol: 17 Page: 149-56 August 2003
C. Jenkins; A. J. Lawson; T. Cheasty; G. A. Willshaw; P. Wright; G. Dougan; G. Frankel; H. R. Smith
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The aim of this study was to examine the incidence of acute-onset presumed infectious endophthalmitis following cataract surgery in the United Kingdom and provide epidemiological data on presentation, management, microbiology, and endophthalmitis cases
Abstract:
AIMS: To estimate the incidence of acute-onset presumed infectious endophthalmitis (PIE) following cataract surgery in the UK and provide epidemiological data on the presentation, management, microbiology, and outcome of cases of endophthalmitis. METHODS: Cases were identified prospectively by active surveillance through the British Ophthalmological Surveillance Unit reporting card more...
International Classification:
Diseases of the eye and adnexa - Disorders of vitreous body and globe - endophthalmitis
Categories:
endophthalmitis
Geography:
the United Kingdom
Eye,
Vol: 18 Page: 580-7 June 2004
S. Kamalarajah; G. Silvestri; N. Sharma; A. Khan; B. Foot; R. Ling; G. Cran; R. Best
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The aim of this study was to examine the incidence, detection patterns, current management, and intraocular pressure control at 1 year in children
Abstract:
PURPOSE: Pediatric glaucoma is a rare, potentially blinding condition, yet, in the United Kingdom, there is a paucity of contemporary epidemiologic and clinical data regarding this condition. The British Infantile and Childhood Glaucoma (BIG) Eye Study is the first national population-based study conducted to examine the incidence, detection patterns, current management, and intraocular more...
International Classification:
Other - intraocular pressure
Categories:
intraocular pressure
Geography:
the United Kingdom
Invest Ophthalmol Vis Sci,
Vol: 48 Page: 4100-6 September 2007
M. Papadopoulos; N. Cable; J. Rahi; P. T. Khaw
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The aim of this study was to examine an annual report on the population of the UK on one specific topic - fertility
Abstract:
The population of the UK is currently growing at its fastest rate since the 1960s, increasing by two and a half per cent between mid-2001 and mid-2006. While life expectancy continues to increase, fertility rates have also been increasing in the last five years and are currently at their highest level since 1980. In addition, international migration has led to the UK population growing more...
International Classification:
Other - fertility
Categories:
fertility
Geography:
the United Kingdom
Popul Trends,
2007 Winter
K. Dunnell
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The aim of this study was to examine standardised clinical caries examinations of 121.550 14-year-old children
Abstract:
DESIGN: This paper reports the results of standardised clinical caries examinations of 121.550 14-year-old children from across the United Kingdom, Jersey and the Isle of Man. These 1998/99 coordinated surveys are the latest in a series which seeks to monitor the dental health of children and to assess the delivery of dental services. METHOD: The criteria and conventions of the British more...
International Classification:
Dental
Categories:
dental caries
Geography:
the United Kingdom
Community Dent Health,
Vol: 17 Page: 48-53 March 2000
N. B. Pitts; D. J. Evans; Z. J. Nugent
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The aim of this study was to report the results of standardised clinical caries examinations of 176,781 5-year-old children
Abstract:
OBJECTIVE: This paper reports the results of standardised clinical caries examinations of 176,781 5-year-old children from across the United Kingdom. These 1997/98 co-ordinated surveys are the latest in a series which seek to monitor the dental health of children and to assess the delivery of dental services. METHOD: The criteria and conventions of the British Association for the Study more...
International Classification:
Dental
Categories:
caries
Geography:
the United Kingdom
Community Dent Health,
Vol: 16 Page: 50-6 March 1999
N. B. Pitts; D. J. Evans; Z. J. Nugent
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The aim of this study was to report survey-derived estimates of dentinal caries experience of children, consider trends and changes in disease presentation
Abstract:
BACKGROUND: The 2003 Children's Dental Health Survey is the fourth in a series of decennial national children's dental health surveys. AIMS: This paper reports the survey-derived estimates of dentinal caries experience of children aged five, eight, 12 and 15 years, considering the trends over recent decades and the position in 2003 following changes in disease presentation and the use more...
International Classification:
Dental
Categories:
dentinal caries
Geography:
the United Kingdom
Br Dent J,
Vol: 200 Page: 313-20 March 2006
N. B. Pitts; I. G. Chestnutt; D. Evans; D. White; B. Chadwick; J. G. Steele
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The aim of this study was to examine the relationship of maternal employment characteristics, day care arrangements and the type of maternity leave pay to breast-feeding for at least 4 months
Abstract:
OBJECTIVE: To examine the relationship of maternal employment characteristics, day care arrangements and the type of maternity leave pay to breast-feeding for at least 4 months. DESIGN: Cohort study. SETTING: Babies aged 9 months in the Millennium Cohort Study, born between September 2000 and January 2002. SUBJECTS: A total of 6917 British/Irish white employed mothers with singleton more...
International Classification:
Other - maternal employment characteristics
Categories:
maternal employment characteristics
Geography:
the United Kingdom
Public Health Nutr,
Vol: 10 Page: 891-6 September 2007
S. S. Hawkins; L. J. Griffiths; C. Dezateux; C. Law
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The aim of this study was to examine epidemiological, clinical & laboratory characteristics of juvenile dermatomyositis in a national multi-centre cohort, to review recent changes in the understanding of management and prognosis in the light of these data
Abstract:
OBJECTIVES: To identify epidemiological, clinical and laboratory characteristics of juvenile dermatomyositis (JDM) in a national multi-centre cohort of patients, and to review recent changes in the understanding of management and prognosis in the light of these data. METHODS: All children with idiopathic inflammatory myositis recruited to the Juvenile Dermatomyositis National Registry more...
International Classification:
Diseases of the musculoskeletal system and connective tissue - Systemic connective tissue disorders - dermatomyositis
Categories:
juvenile dermatomyositis
Geography:
Republic of Ireland and the United Kingdom
Rheumatology (Oxford),
Vol: 45 Page: 1255-60 October 2006
L. J. McCann; A. D. Juggins; S. M. Maillard; L. R. Wedderburn; J. E. Davidson; K. J. Murray; C. A. Pilkington
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This study aimed to explore the standardization of measurement of blood pressure and the detection of hypertension in children and adolescents
Abstract:
Despite the publication of several expert committee guidelines for the measurement of blood pressure (BP) and the diagnosis of hypertension in children and adolescents, it was our perception and clinical experience that there still appeared to be a general lack of standardisation of BP measurement techniques and little consensus on the criteria for diagnosing hypertension. To more...
International Classification:
Practice/knowledge - blood pressure
Categories:
blood pressure;
Geography:
Republic of Ireland and the United Kingdom
J Hum Hypertens,
Vol: 15 Page: 419-23 June 2001
G. Y. Lip; M. Beevers; D. G. Beevers; M. J. Dillon
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This article discusses the "The Millennium Cohort Study"
Abstract:
The Millennium Cohort Study is the latest in the line of British birth cohort studies. MCS resembles its predecessors which follow people born in 1946, 1958 and 1970 in the intention to become multi-purpose longitudinal data resource charting many aspects of individual's lives over time. The families of a sample of around 20,000 babies are being interviewed during 2001-02, when eligible more...
Geography:
the United Kingdom
Popul Trends,
2002 Spring
K. Smith; H. Joshi
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The aim of this study was to examine the changing demographic profile of diagnosed HIV-infected pregnant women over time and trends in pregnancy outcome, uptake of interventions and mother-to-child transmission
Abstract:
OBJECTIVE: To describe the changing demographic profile of diagnosed HIV-infected pregnant women over time and trends in pregnancy outcome, uptake of interventions and mother-to-child transmission. DESIGN: National surveillance study. SETTING: UK and Ireland. POPULATION: Diagnosed HIV-infected pregnant women, 1990-2006. METHODS: Active surveillance of obstetric and paediatric HIV more...
International Classification:
Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV
Categories:
HIV-infected pregnance; uptake of interventions; mother-to-child transmission of HIV
Geography:
Republic of Ireland and the United Kingdom
Bjog,
Vol: 115 Page: 1078-86 August 2008
C. L. Townsend; M. Cortina-Borja; C. S. Peckham; P. A. Tookey
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The aim of this study was to estimate the proportion of tuberculosis treatment success and to identify predictors of non-completion for cases reported
Abstract:
BACKGROUND: Tuberculosis treatment outcome monitoring was introduced in England, Wales and Northern Ireland in 2002 based on cases reported in 2001. OBJECTIVE: To estimate the proportion of treatment success and to identify predictors of non-completion for cases reported in 2001. Method: At 12 months after the start of treatment, outcome was assessed according to a protocol based on more...
International Classification:
Certain infectious and parasitic diseases - Tuberculosis - tuberculosis
Categories:
tuberculosis
Geography:
the United Kingdom
J Epidemiol Community Health,
Vol: 61 Page: 302-7 April 2007
D. Antoine; C. E. French; J. Jones; J. M. Watson
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This article discusses the review of the 20 years of the British Paediatric Surveillance Unit
Geography:
the United Kingdom
Euro Surveill,
Vol: 11 Page: E060720 4 2006
R. M. Lynn; R. Pebody; R. Knowles
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The aim of this study was to examine the level of violence against trainee paediatricians
Abstract:
BACKGROUND: Much research has looked at the extent of violence against doctors, but this has been restricted mainly to psychiatry, general practice, and accident and emergency. AIMS: To assess the level of violence against trainee paediatricians. METHODS: A telephone questionnaire was addressed to 25 specialist registrars/senior registrars/senior SHOs in each of three regions in the UK: more...
International Classification:
War, violence and conflict
Categories:
violence against trainee paediatrician
Geography:
the United Kingdom
Arch Dis Child,
Vol: 84 Page: 106-8 February 2001
J. G. Mackin
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