Irish Child Health Database - Peer Reviewed Papers
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This study examined the major factors affecting graft survival in cadaveric kidney transplants
Abstract:
In corneal transplants the risks of acute rejection and graft failure decrease with increasing recipient age, but kidney graft survival analyses tend to show the opposite effect. Why is this? Cadaveric kidney transplants performed in the UK and Republic of Ireland between 1985 and 1993 (UKTSSA database) were analysed by multifactorial methods to identify major factors affecting graft more...
International Classification:
Organ transplants - renal
Categories:
major factors affecting kidney transplants graft survival
Geography:
Republic of Ireland and the United Kingdom
Transpl Int,
Vol: 13 Suppl 1 Page: S42-4 2000
B. A. Bradley
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The aim of this study was to determine the effect of further vaginal delivery on anal sphincter function in women after apparently uncomplicated primiparous forceps delivery
Abstract:
PURPOSE: The study was designed to determine the effect of further vaginal delivery on anal sphincter function in women after apparently uncomplicated primiparous forceps delivery. METHODS: Fifty-two secundigravid women whose first child was forceps-assisted were compared with a control group of 20 women who had undergone spontaneous first vaginal delivery. Both groups were studied more...
International Classification:
Pregnancy, childbirth and the puerperium - anal sphincter function
Categories:
uncomplicated primiparous forceps delivery; -vaginal delivery; anal sphincter function
Geography:
Republic of Ireland
Dis Colon Rectum,
Vol: 51 Page: 1361-6 September 2008
R. Mahony; M. Behan; P. R. O'Connell; C. O'Herlihy
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The aim of this study was to examine whether low parental social class increases children's risk of subsequently developing Schizophrenia or modifies the presentation
Abstract:
OBJECTIVES: To examine if low parental social class increases children's risk of subsequently developing schizophrenia or modifies the presentation. DESIGN: Case-control study with historical controls. SETTING: Geographically defined region in south Dublin. Participants: 352 patients with first presentation of schizophrenia matched with the next registered same sex birth from the same more...
International Classification:
Mental and behavioural disorders - Schizophrenia, schizotypal and delusional disorders - schizophrenia
Categories:
low parental social class; -Schizophrenia
Geography:
Republic of Ireland
Bmj,
Vol: 323 Page: 1398-401 December 2001
F. Mulvany; E. O'Callaghan; N. Takei; M. Byrne; P. Fearon; C. Larkin
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The aim of this study was to examine the relation between clinical risk factors and refractive development among preterm infants without retinopathy of prematurity
Abstract:
BACKGROUND/AIMS: Even in the absence of retinopathy of prematurity (ROP), premature birth signals increased risk for abnormal refractive development. The present study examined the relation between clinical risk factors and refractive development among preterm infants without ROP. METHODS: Cycloplegic refraction was measured at birth, term, 6, 12, and 48 months corrected age in a cohort more...
International Classification:
Diseases of the eye and adnexa - Disorders of choroid and retina - retinopathy of prematurity
Categories:
retinopathy of prematurity
Geography:
Northern Ireland
Br J Ophthalmol,
Vol: 86 Page: 1035-40 September 2002
K. J. Saunders; D. L. McCulloch; A. J. Shepherd; A. G. Wilkinson
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This article discusses epidemiology consideration in elucidating environmental causes of birth defects.
Abstract:
Epidemiology can be used to elucidate environmental causes of birth defects. This paper discusses 1) different types of environmental causes; 2) the difficulties in comparing the prevalence of birth defects between populations, including the need for a population base and the implications of prenatal diagnosis; 3) the main study designs for observational epidemiological studies and the more...
Geography:
Northern Ireland
Am J Med Genet C Semin Med Genet,
Vol: 125C Page: 4-11 February 2004
H. Dolk
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This study reports on epidemiological and virological assessment of influenza activity in Europe during the 2003-2004 season
Abstract:
The 2003-2004 influenza season in Europe was dominated by the spread of the new drift variant A/Fujian/411/2002 (H3N2)-like virus which was not perfectly matched with the A(H3N2) component of the influenza vaccine. Sporadic cases of this virus were detected in Europe at the end of the 2002-2003 season and influenza activity associated with this virus began relatively early during the more...
International Classification:
Surveillance - Diseases of the respiratory system - Influenza and pneumonia - influenza
Categories:
virological assessment; influenza
Geography:
International
Euro Surveill,
Vol: 10 Page: 107-11 April 2005
W. J. Paget; T. J. Meerhoff; A. Meijer
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This study reports on epidemiological and virological assessment of influenza activity in Europe during the 2004-2005 winter
Abstract:
The 2004-2005 influenza season in Europe started in late December 2004 and the first influenza activity occurred in the west and southwest (Spain, United Kingdom and Ireland). Influenza activity then moved gradually east across Europe during January and early February 2005, and from late February until late March, most movement was south to north. The intensity of clinical influenza more...
International Classification:
Surveillance - Diseases of the respiratory system - Influenza and pneumonia - influenza
Categories:
virological assessment; influenza
Geography:
International
Euro Surveill,
Vol: 11 Page: 111-8 2006
A. Meijer; W. J. Paget; T. J. Meerhoff; C. S. Brown; L. E. Meuwissen; J. van der Velden
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The aim of this study was to examine the epidemiology of hepatitis C infection in the ERHA/HSE Eastern region
Abstract:
Hepatitis C became statutorily notifiable in Ireland on 1 January 2004. Prior to 2004, only hepatitis A and hepatitis B were notifiable as distinct types of hepatitis. A third category notifiable under the Infectious Diseases Regulations 1981 was "viral hepatitis unspecified". The majority of cases notified under this heading were thought to be due to infection with hepatitis more...
International Classification:
Certain infectious and parasitic diseases - Viral hepatitis - hepatitis C
Categories:
hepatitis C
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 365-6 February 2007
M. O. Meara; J. Barry; L. Mullen
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The aim of this study was to investigate whether six common polymorphisms in the TCII gene influence neural tube defect risk
Abstract:
BACKGROUND: Decreased maternal folate levels are associated with having a child with a neural tube defect (NTD), and periconceptual folic acid supplementation reduces this risk by >50%. Vitamin B(12) (as methylcobalamin) is a cofactor for methionine synthase, an enzyme that plays a key role in folate metabolism. Alterations in vitamin B(12) metabolism may influence the development of more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - neural tube defects - condiction
Categories:
six common polymorphisms; -neural tube defect
Geography:
Republic of Ireland
Birth Defects Res A Clin Mol Teratol,
Vol: 73 Page: 239-44 April 2005
D. A. Swanson; F. Pangilinan; J. L. Mills; P. N. Kirke; M. Conley; A. Weiler; T. Frey; A. Parle-McDermott; V. B. O'Leary; R. R. Seltzer; K. A. Moynihan; A. M. Molloy; H. Burke; J. M. Scott; L. C. Brody
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The aim of this study was to investigate factors associated with high caries levels in 5-year-old children in the Kerry Community Care Area of the Southern Health Board in Ireland
Abstract:
OBJECTIVE: To investigate the factors associated with high caries levels in 5-year-old children in the Kerry Community Care Area of the Southern Health Board in Ireland. DESIGN: Cross-sectional study. SETTING: County Kerry, Ireland in 1997. SUBJECTS: A random sample of 5-year-old children. METHOD: Six hundred and thirty-six 5-year-old children were examined for caries following WHO more...
International Classification:
Dental
Categories:
caries
Geography:
Republic of Ireland
Community Dent Health,
Vol: 18 Page: 72-8 June 2001
M. I. Creedon; D. M. O'Mullane
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The aim of this study was to examine the prevalence of resorption for intruded permanent teeth and the effect of factors on the timing, prevalence and rate of resorption
Abstract:
There is a lack of consensus concerning the management of intruded permanent teeth. The objectives of the present study were to determine the prevalence of resorption for intruded permanent teeth and to establish the effect of factors on the timing, prevalence and rate of resorption and to examine the relationship between the timing of onset and the subsequent rate of resorption. more...
International Classification:
Dental
Categories:
prevalence of resorption for intruded permanent teeth
Geography:
Northern Ireland
Dent Traumatol,
Vol: 18 Page: 73-6 April 2002
S. Al-Badri; M. Kinirons; B. Cole; R. Welbury
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This study examined factors associated with internal hip rotation gait in patients with cerebral palsy
Abstract:
Internal rotation gait is common in children with cerebral palsy. Factors thought to contribute include femoral anteversion, hip flexor tightness, imbalance of hip rotators, and hamstring and adductor tightness. The exact cause of internal rotation must be defined before contemplating surgery. We investigated the prevalence of internal hip rotation and associated factors, which are more...
International Classification:
Other - internal hip rotation gait
Categories:
internal hip rotation gait
Geography:
Republic of Ireland
J Pediatr Orthop,
Vol: 26 Page: 537-41 2006 Jul-Aug
R. O'Sullivan; M. Walsh; P. Hewart; A. Jenkinson; L. A. Ross; T. O'Brien
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The aim of this study was to examine the epidemiology of multiple sclerosis the North-East of Northern Ireland using multiple sources of case ascertainment, and the Poser criteria for definite or probable or the McDonald criteria
Abstract:
BACKGROUND: Northern Ireland is recognized as an area of high risk for multiple sclerosis. The original study of Allison and Millar in 1951 found a prevalence of 51/100,000 and mean annual incidence of 2.74/100,000/year. Subsequent studies in 1961, 1986, and 1996 suggested rising prevalence--80, 138, and 168.2/100,000, respectively. METHODS: In 2004, we surveyed the North-East of more...
International Classification:
Diseases of the nervous system - Demyelinating diseases of the central nervous system - multiple sclerosis
Categories:
multiple sclerosis
Geography:
Republic of Ireland
Mult Scler,
Vol: 14 Page: 880-6 August 2008
O. M. Gray; G. V. McDonnell; S. A. Hawkins
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The aim of this study was to identify risk factors for sudden infant death syndrome in the sleeping environment of Irish infants
Abstract:
AIM: To identify risk factors for sudden infant death syndrome (SIDS) in the sleeping environment of Irish infants. METHODS: A five year population based case-control study with parental interviews conducted for each case and three controls matched for age, place of birth, and last sleep period. A total of 203 SIDS cases and 622 control infants born 1994-98 were studied. RESULTS: In a more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
sleeping environment; -sudden infant death syndrome
Geography:
Republic of Ireland
Arch Dis Child,
Vol: 88 Page: 1058-64 December 2003
C. McGarvey; M. McDonnell; A. Chong; M. O'Regan; T. Matthews
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The aim of this study was to describe the impact of sex on familial vesicoureteral reflux
Abstract:
PURPOSE: Familial clustering of vesicoureteral reflux implies that genetic factors have an important role in the pathogenesis of vesicoureteral reflux. We investigated the impact of sex on familial vesicoureteral reflux. MATERIALS AND METHODS: Between 1998 and 2003 we identified 159 white families with at least 2 children (range 2 to 5) with vesicoureteral reflux confirmed by a voiding more...
International Classification:
Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux
Categories:
renal scarring in familial vesicoureteral reflux
Geography:
Republic of Ireland
J Urol,
Vol: 176 Page: 1776-80 October 2006
M. E. Pirker; N. Mohanan; E. Colhoun; D. Barton; A. Green; P. Puri
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The aim of this study was to examine the independence and relative strengths of association between coronary heart disease risk status and both body fatness and cardiorespiratory (C-R) fitness in 12- and 15-yr-old adolescents
Abstract:
PURPOSE: The purpose of this study was to examine the independence and relative strengths of association between coronary heart disease (CHD) risk status and both body fatness and cardiorespiratory (C-R) fitness in 12- and 15-yr-old adolescents. METHODS: The study cohort consisted of 1015 schoolchildren aged 12 and 15 yr (251 12-yr-old boys, 258 12-yr-old girls, 252 15-yr-old boys, and more...
International Classification:
Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - obesity
Categories:
body fatness; cardiorespiratory fitness
Geography:
Northern Ireland
Med Sci Sports Exerc,
Vol: 33 Page: 270-4 February 2001
C. Boreham; J. Twisk; L. Murray; M. Savage; J. J. Strain; G. Cran
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This article discusses the only proven risk associated with water fluoridation: enamel fluorosis. Its purpose is to review current methods of measuring enamel fluorosis, its aetiology and metabolism
Abstract:
OBJECTIVES: This paper is primarily concerned with the only proven risk associated with water fluoridation: enamel fluorosis. Its purpose is to review current methods of measuring enamel fluorosis, its aetiology and metabolism. A further objective is to identify risk factors to reduce the prevalence of enamel fluorosis and employ methods to manage such risk factors. DATA: The prevalence more...
Geography:
Republic of Ireland
J Dent,
Vol: 33 Page: 177-86 March 2005
D. Browne; H. Whelton; D. O'Mullane
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The aim of this study was to whether genetic risk for psychosis related to differences in foetal brain development as measured by prenatal ultrasonography
Abstract:
Cerebral ventricular enlargement and reduced cortical volume are correlates of chronic schizophrenia. We investigated whether genetic risk for psychosis related to differences in foetal brain development as measured by prenatal ultrasonography. Routine foetal cerebral measures at 19-23 weeks of gestation were compared between the offspring of 35 women with a history of psychosis and 105 more...
International Classification:
Mental and behavioural disorders - psychosis
Categories:
foetal brain development; -psychosis
Geography:
the United Kingdom
Br J Psychiatry,
Vol: 190 Page: 445-6 May 2007
M. C. Clarke; M. Cannon; M. W. Hogg; M. N. Marks; S. Conroy; S. J. Pawlby; A. Greenough; K. Nicolaides
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This article discusses aspects of true food allergies, implying immune-mediated adverse responses to food antigens, discussing the importance of IgE-mediated and non-IgE-mediated immune mechanisms
Abstract:
Adverse reactions to foods are commonly implicated in the causation of ill health. However, foreign antigens, including food proteins and commensal microbes encountered in the gastrointestinal tract, are usually well tolerated. True food allergies, implying immune-mediated adverse responses to food antigens, do exist, however, and are especially common in infants and young children. more...
Geography:
Republic of Ireland
Curr Gastroenterol Rep,
Vol: 4 Page: 373-82 October 2002
P. F. O'Leary; F. Shanahan
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This article discusses the published literature on fungal endocarditis in children and to discuss the incidence due to a wide range of fungi, primarily Aspergillus and Candida species
Abstract:
Fungal endocarditis in the neonate and pediatric population is associated with a high degree of morbidity and mortality, with diagnosis in the majority of cases made postmortem. The aim of this article is to review published literature on fungal endocarditis in children and to discuss the incidence due to a wide range of fungi, primarily Aspergillus and Candida species, as well as its more...
Geography:
Northern Ireland
Pediatr Cardiol,
Vol: 26 Page: 517-36 2005 Sep-Oct
B. C. Millar; J. Jugo; J. E. Moore
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This study determined the nature and frequency of golf related eye injury at our unit from 1990 to 2007
Abstract:
Golf related ocular injuries are uncommon but frequently result in severe injury necessitating removal of the eye. As golf increases in popularity, it is vital that awareness is raised among both players and spectators regarding the potential hazards. We determined the nature and frequency of golf related eye injury at our unit from 1990 to 2007. Patient age, nature of injury, more...
International Classification:
Injury, poisoning and certain other consequences of external causes - injury
Categories:
golf related eye injury
Geography:
Republic of Ireland
Ir Med J,
Vol: 101 Page: 167-9 June 2008
D. Townley; C. Kirwan; M. O'Keefe
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The aim of this study was to identified cases of invasive group B streptococcal disease in infants younger than 90 days through surveillance involving paediatricians, microbiologists, and parents
Abstract:
The incidence, morbidity, and mortality of group B streptococcal disease in the UK and Republic of Ireland are largely unknown. Between Feb 1, 2000, and Feb 28, 2001, we identified cases of invasive group B streptococcal disease in infants younger than 90 days through surveillance involving paediatricians, microbiologists, and parents. 568 cases were identified, equivalent to a total more...
International Classification:
Bacterium - Group B Strep
Categories:
Group B Strep
Geography:
Republic of Ireland and the United Kingdom
Lancet,
Vol: 363 Page: 292-4 January 2004
P. T. Heath; G. Balfour; A. M. Weisner; A. Efstratiou; T. L. Lamagni; H. Tighe; L. A. O'Connell; M. Cafferkey; N. Q. Verlander; A. Nicoll; A. C. McCartney
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This review summarises recent publications about the role of indicators in gathering optimal health information on behalf of people with intellectual disability
Abstract:
PURPOSE OF REVIEW: Health disparities are evident between people with intellectual disabilities and the general population. Despite the potential of indicators for measuring disparities and planning interventions to address inequalities- currently a priority health policy target- few studies have mapped the physical or mental health of people with intellectual disabilities onto the more...
Geography:
Republic of Ireland
Curr Opin Psychiatry,
Vol: 21 Page: 474-8 September 2008
P. N. Walsh
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This study assess the predictability of the initial herring classification
Abstract:
The Herring lateral pillar classification has been shown to be a useful predictor of subsequent femoral head deformity in Perthes disease. The initial Herring classification, however, can often be misleading with regard to outcome, as further collapse can occur. The purpose of this study was to assess the predictability of the initial Herring classification. The radiographs of 253 more...
International Classification:
Predictability of herring classification
Categories:
predictability; herring classification
Geography:
Northern Ireland
J Pediatr Orthop,
Vol: 22 Page: 479-82 2002 Jul-Aug
K. Lappin; D. Kealey; A. Cosgrove
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The aim of this study was to examine the magnitude of "weekends on deaths" in British data in relation to the "back to sleep" campaign.
Abstract:
BACKGROUND: An increased incidence of sudden infant death syndrome (SIDS) at weekends has been previously noted, although it has not been found in all studies. Where a weekend effect has been found it is most prominent on Sundays. AIM: To identify the magnitude of this effect in British data before and after the fall in prevalence associated with the "back to sleep" campaign. more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
sudden infant death syndrome
Geography:
the United Kingdom
Arch Dis Child,
Vol: 89 Page: 670-2 July 2004
J. A. Mooney; P. J. Helms; I. T. Jolliffe
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The aim of this study was to investigate a large cohort of children with juvenile dermatomyositis, and those with JDM-scleroderma (JDM-SSc) overlap, using detailed serological analysis, HLA class II genotyping and clinical characterization.
Abstract:
OBJECTIVES: To investigate a large cohort of children with juvenile dermatomyositis (JDM), and those with JDM-scleroderma (JDM-SSc) overlap, using detailed serological analysis, HLA class II genotyping and clinical characterization. METHODS: Children (114) with JDM were recruited, and clinical data collected, through the JDM National Registry and Repository (UK and Ireland). Sera were more...
International Classification:
Diseases of the musculoskeletal system and connective tissue - Systemic connective tissue disorders - dermatomyositis
Categories:
HLA class II genotyping; juvenile dermatomyositis
Geography:
Republic of Ireland and the United Kingdom
Rheumatology (Oxford),
Vol: 46 Page: 1786-91 December 2007
L. R. Wedderburn; N. J. McHugh; H. Chinoy; R. G. Cooper; F. Salway; W. E. Ollier; L. J. McCann; H. Varsani; J. Dunphy; J. North; J. E. Davidson
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This article discusses the available literature to consider the impact of risk factors on young people who use and misuse substances and whether social exclusion and psychiatric disorders constitute important risk factors
Abstract:
The present review examines the available literature to consider the impact of risk factors on young people who use and misuse substances. We discuss the existing evidence to argue that social exclusion and psychiatric disorders constitute the important risk factors in the development of substance misuse. We examine the role that risk factors play by considering recent studies of more...
Geography:
International
Current Opinion in Psychiatry,
Vol: 15 Page: 355-360 2002
Helen D. Bushell; Ilana Crome; Richard Williams
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The aim of this study was to determine the prevalence of hyponatremia during carbamazepine treatment in patients with Intellectual Disability, and to investigate the risk factors and clinical features of this condition
Abstract:
Carbamazepine is an anticonvulsant and psychotropic medication commonly used in the treatment of people with intellectual disability (ID). The incidence of hyponatremia during treatment in this population is unclear. The present study aimed to determine the prevalence of hyponatremia during carbamazepine treatment in patients with ID, and to investigate the risk factors and clinical more...
International Classification:
Mental and behavioural disorders - Mental retardation - Intellectual disabilities
Categories:
hyponatremia; carbamazepine treatment; -Intellectual Disability
Geography:
Republic of Ireland
J Intellect Disabil Res,
Vol: 45 Page: 152-6 April 2001
B. D. Kelly; J. Hillery
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This study undertook a prospective analysis of all patients presenting to their unit with fractures sustained while Rollerblading or skateboarding over a 5-month period
Abstract:
Dedicated skate parks have led to an increase in pediatric fractures referred to the authors' unit. The authors performed a prospective analysis of all patients presenting to their unit with fractures sustained while Rollerblading or skateboarding over a 5-month period. Epidemiologic data, user experience, wearing of protective gear, place of injury, and mechanism of injury were more...
International Classification:
Injury, poisoning and certain other consequences of external causes - fractures
Categories:
fractures
Geography:
Republic of Ireland
J Pediatr Orthop,
Vol: 23 Page: 440-2 2003 Jul-Aug
E. Sheehan; K. J. Mulhall; S. Kearns; P. O'Connor; F. McManus; M. Stephens; D. McCormack
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The aim of this study was to examine the emergence of Vancomycin-resistant enterococci amongst our cohort of renal replacement therapy patients posed considerable challenges in our attempts to prevent spread
Abstract:
Vancomycin-resistant enterococci (VRE) commonly colonize, but less frequently infect, debilitated patients, such as those on chronic renal dialysis. The emergence of VRE amongst our cohort of renal replacement therapy patients posed considerable challenges in our attempts to prevent spread. Although 60 of 451 (13%) patients became colonized, only two patients required systemic more...
International Classification:
Vancomycin resistant enterococci
Categories:
vancomycin resistant enterococci
Geography:
Republic of Ireland
J Hosp Infect,
Vol: 58 Page: 28-33 September 2004
H. Humphreys; V. Dolan; T. Sexton; P. Conlon; L. Rajan; E. Creamer; J. Walshe; J. Donohoe; E. G. Smyth
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This article discusses incorporating a gender dimension in food allergy research
Abstract:
Sex and gender are the major determinants of health and disease in both men and women. The aim of this review paper was to examine differences in gender and sex in relation to the prevalence and effects of food allergy. There are still major gaps in our knowledge about the kinds of processes which shape men's and women's perceptions and experiences of food allergy. The expression and more...
Geography:
Republic of Ireland
Allergy,
Vol: 61 Page: 1336-43 November 2006
A. DunnGalvin; J. O. Hourihane; L. Frewer; R. C. Knibb; J. N. Oude Elberink; I. Klinge
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The aim of this study was to examine International Child Care Practices Study on the key sudden infant death syndrome risk factors of infant sleep position and parental smoking
Abstract:
Presents data from the International Child Care Practices Study, provided by 17 countries, on the key sudden infant death syndrome (SIDS) risk factors of infant sleep position and parental smoking. Parents of 4,639 infants were surveyed at birth by interview, and at 3 mo of age by postal questionnaire. Overall, 52.5% of infants were placed in the supine or back sleep position, 37.8% in more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
sudden infant death syndrome
Geography:
International
Early Human Development,
Vol: 64 Page: 7-20 2001
E. A. S. Nelson; B. J. Taylor
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The aim of this study was to investigate positive health and its associations with supportive relationships with friends and family members, we conducted an analysis of data from the 2002 Irish Health Behaviour in School-Aged Children Study
Abstract:
To investigate positive health and its associations with supportive relationships with friends and family members, we conducted an analysis of data from the 2002 Irish Health Behaviour in School-Aged Children Study (HBSC); a cross-sectional survey of 8,424 Irish schoolchildren aged 10-18. 36.0% and 63.4% of the students reported lack of emotional and physical symptoms respectively, more...
International Classification:
Other - supportive relationships
Categories:
positive health; supportive relationships
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: suppl 33-6 September 2007
M. Molcho; S. N. Gabhainn; C. C. Kelleher
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The aim of this study was to examine the incidence of invasive pneumococcal disease in children in Ireland
Abstract:
BACKGROUND: Streptococcus pneumoniae is an important cause of childhood illness. Recently a safe and effective 7-valent conjugate pneumococcal vaccine for children has been licensed in the EU. AIMS: To calculate the incidence of invasive pneumococcal disease (IPD) in children in Ireland, to estimate the burden of disease and to anticipate the protective effect of the conjugate vaccine. more...
International Classification:
Bacterium - pneumococcal disease
Categories:
invasive pneumococcal disease
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 177 Page: 225-31 September 2008
J. J. Fitzsimons; A. L. Chong; M. T. Cafferkey; K. M. Butler
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This article discusses iron deficiency anemia and childhood stroke
Geography:
Republic of Ireland
Ir Med J,
Vol: 101 Page: 165 June 2008
D. O'Rourke; R. McCarthy; B. Lynch
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This article discusses whether Helicobacter pylori infection in childhood is a risk factor for gastric cancer
Abstract:
Helicobacter pylori infection is associated with chronic gastritis and peptic ulcer disease. Furthermore, the World Health Organization has classified this organism as a carcinogen for gastric cancer. H pylori infection is mainly acquired in childhood. Children with H pylori infection are asymptomatic except for a very small number that develop peptic ulcer disease. However, if H pylori more...
Geography:
Republic of Ireland
Pediatrics,
Vol: 107 Page: 373-80 February 2001
C. Imrie; M. Rowland; B. Bourke; B. Drumm
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This article discusses the relationship between components of the diet and inflammatory bowel disease, including ulcerative colitis and Crohn's disease
Abstract:
Inflammatory bowel disease (IBD) is a chronic inflammatory process, the aetiology of which is complex and probably multi-factorial. Nutrition has been proposed to be an important aetiological factor for IBD. The present review critically examines the relationship between components of the diet (such as sugar, fat, fibre, fruit and vegetables, and protein) and IBD, including ulcerative more...
Geography:
Republic of Ireland
Eur J Gastroenterol Hepatol,
Vol: 15 Page: 607-13 June 2003
K. D. Cashman; F. Shanahan
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The aim of this study was to audit occurrence of postoperative hemorrhage after tonsillectomy and risk factors for these complications
Abstract:
OBJECTIVES: Investigation of the occurrence of postoperative hemorrhage after tonsillectomy and risk factors for these complications. STUDY DESIGN: Prospective National Audit with electronic web-based data collection from the National Health Service and independent hospitals in England and Northern Ireland. METHODS: Consenting patients undergoing tonsillectomy between July 2003 and more...
International Classification:
Procedure - tonsillectomy
Categories:
postoperative tonsillectomy hemorrhaging
Geography:
the United Kingdom
Laryngoscope,
Vol: 117 Page: 717-24 April 2007
D. Lowe; J. van der Meulen; D. Cromwell; J. Lewsey; L. Copley; J. Browne; M. Yung; P. Brown
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The aim of this study was to identify the reasons for the late presentation of developmental dysplasia of the hip in the presence of a screening programme
Abstract:
BACKGROUND: A neonatal screening programme for developmental dysplasia of the hip (DDH) is ongoing in Cork. Despite early screening, infants continue to present at later ages with DDH. The impact of late diagnosis is significant. Established DDH causes significant morbidity and may have major medicolegal implications. AIM: To identify the reasons for the late presentation of DDH in the more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Congenital malformations and deformations of the musculoskeletal system - dysplasia of the hip
Categories:
developmental dysplasia of the hip
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 171 Page: 139-40 2002 Jul-Sep
R. Gul; J. C. Coffey; G. Khayyat; A. J. McGuinness
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The aim of this study was to describe linkage disequilibrium mapping at DAT1, DRD5 and DBH to narrow the search for attention-deficit hyperactivity disorder susceptibility alleles at these loci
Abstract:
Abnormalities in dopaminergic neurotransmission are now accepted as factors in predisposing to ADHD. Evidence of associations between dopamine transporter gene polymorphism and ADHD was first reported by Cook et al. We confirmed the DAT1 association and also identified two additional susceptibility loci at the DRD5 and DBH. Notably, none of the associated variants at these three genes more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
Republic of Ireland
Mol Psychiatry,
Vol: 8 Page: 299-308 March 2003
Z. Hawi; N. Lowe; A. Kirley; F. Gruenhage; M. Nothen; T. Greenwood; J. Kelsoe; M. Fitzgerald; M. Gill
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This study examined the risk factors in the development of enterocolitis and the long-term outcome in patients with Hirschsprung's disease
Abstract:
Enterocolitis remains the most serious complication of Hirschsprung's disease (HD). The purpose of this study was to evaluate the risk factors in the development of enterocolitis and the long-term outcome in these patients. The hospital records of 259 consecutive patients with HD during 1975-2003 were examined. The data was analysed for age at presentation, associated anomalies, level more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease
Categories:
Hirschsprung's disease
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 22 Page: 316-8 April 2006
M. Menezes; P. Puri
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The aim of this study was to test the hypothesize that exposure to antenatal risk factors for sepsis alters the perinatal neutrophil phenotype
Abstract:
The diagnosis of neonatal sepsis is difficult, resulting in unnecessary treatment to minimize morbidity and mortality. We hypothesized that exposure to antenatal risk factors for sepsis alters the perinatal neutrophil phenotype. The study setting was a tertiary referral university-affiliated maternity and neonatal hospital. Neutrophils from adults, normal neonates, neonates with more...
International Classification:
Pregnancy, childbirth and the puerperium
Categories:
antenatal sepsis;- altered perinatal neutrophil phenotype
Geography:
Republic of Ireland
Clin Exp Immunol,
Vol: 151 Page: 244-50 February 2008
E. J. Molloy; A. J. O'Neill; J. J. Grantham-Sloan; D. W. Webb; R. W. Watson
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This aim of this study was to examine maternal folate status and neural tube defects in Ireland and the need for a national food fortification program
Abstract:
To determine the present risk of a Neural Tube Defect [NTD] pregnancy in the caucasian primigravid population in Dublin by comparing the serum folate and red cell folate status of primigravid patients attending the first prenatal booking clinic with data from the late 80's. This Cross-sectional population study looking at blood folate status of over 400 sequential primigravid caucasian more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - neural tube defects - condiction
Categories:
maternal folate status; neural tube defects; national food fortification program
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 469-72 May 2007
T. Walsh; S. O'Broin; S. Cooley; J. Donnelly; C. Collins; H. McMillan; R. F. Harrison; C. McMahon; M. Geary
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The aim of this study was to examine the relationship between maternal weight characteristics and recurrence of fetal macrosomia in non-diabetic women delivering a second infant following primparious delivery of a marosomic infant
Abstract:
This study examines the relationship between maternal weight characteristics and recurrence of macrosomia in 111 non-diabetic women who delivered a second baby following primiparous delivery of a macrosomic infant (> 4500 g). Recurrence of fetal macrosomia was associated with greater maternal body mass index (P = 0.032), greater initial pregnancy weight (P < 0.05) and total weight gain more...
International Classification:
Pregnancy, childbirth and the puerperium - fetal macrosomia; non-diabetic women
Categories:
fetal macrosomia; non-diabetic women
Geography:
Republic of Ireland
Aust N Z J Obstet Gynaecol,
Vol: 47 Page: 399-401 October 2007
R. Mahony; M. Foley; F. McAuliffe; C. O'Herlihy
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This article discusses some of the factors involved in normal and abnormal lung modelling and inflammation and glucocorticosteroid-induced remodelling in the perinatal period, in the context of neonatal chronic lung disease, are reviewed
Abstract:
Neonatal chronic lung disease (CLD) is the major long-term pulmonary complication of preterm birth affecting about 20% of infants who need mechanical ventilation. CLD is the result of abnormal repair processes following inflammatory lung injury that lead to remodeling of the lung. Inflammation may be initiated by a variety of stimuli including mechanical ventilation, oxygen toxicity and more...
Geography:
Northern Ireland
Treat Respir Med,
Vol: 4 Page: 347-59 2005
D. G. Sweet; H. L. Halliday
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This study aimed to explore deaths in neonatal intensive care units
Abstract:
With the ever-increasing availability of aggressive medical treatment and technical support, neonatologists are offered an increasing ability to prolong life. While "end-of-life" decisions within NICUs have been studied internationally, there is limited data available for Ireland. Through the auspices of the Irish Faculty of Paediatrics 2002 Neonatal Mortality Ouestionnaire, more...
International Classification:
Practice/knowledge - intensive care neonatal deaths
Categories:
intensive care neonatal deaths
Geography:
Republic of Ireland
Ir Med J,
Vol: 99 Page: 106-8 April 2006
E. Finan; T. Bolger; S. M. Gormally
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This study examined maternal dietary patterns during pregnancy influenced general practitioner diagnosis of asthma by the age of 3 years in the Life-ways cohort of children.
Abstract:
There is increasing evidence that dietary factors in early life play a role in the aetiology of childhood asthma. Our objective in this analysis was to assess whether maternal dietary patterns during pregnancy, as measured by a validated food frequency questionnaire, influenced general practitioner diagnosis of asthma by the age of 3 years in the Life-ways cohort of children. General more...
International Classification:
Longitudinal - Maternal dietary patterns and childhood asthma
Categories:
maternal dietary patterns and childhood asthma
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: suppl 27-32 September 2007
N. Fitzsimon; U. Fallon; D. O'Mahony; B. G. Loftus; G. Bury; A. W. Murphy; C. C. Kelleher
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The aim of this study was to examine the effect of risk factors, including mode of delivery, on the vertical transmission rate of hepatitis C
Abstract:
BACKGROUND: Little information is available about the timing of mother-to-child transmission of hepatitis C virus (HCV), and no interventions to decrease transmission rates have been identified. We examined the effect of risk factors, including mode of delivery, on the vertical transmission rate. METHODS: Data from HCV-infected women and their infants from three hospitals in Ireland and more...
International Classification:
Certain infectious and parasitic diseases - Viral hepatitis - hepatitis C
Categories:
hepatitis C
Geography:
Republic of Ireland and the United Kingdom
Lancet,
Vol: 356 Page: 904-7 September 2000
D. M. Gibb; R. L. Goodall; D. T. Dunn; M. Healy; P. Neave; M. Cafferkey; K. Butler
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This article discusses a life history approach to community rules preventing reoffending by child sex abusers
Abstract:
The Children Act 1989 defines a child as "a person who has not yet reached 18 years of age." In England, Wales, and Scotland the present age of consent for heterosexual and homosexual sex is 16 years and in Northern Ireland it is 17 years. The proportion of young people who report heterosexual intercourse before the age of 16 years increased in the 1990s compared with the more...
Geography:
Northern Ireland
Arch Dis Child,
Vol: 88 Page: 303-11 April 2003
A. Thomas; G. Forster; A. Robinson; K. Rogstad
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This article discusses necrotising enterocolitis and localised intestinal perforation
Geography:
Northern Ireland
Pediatr Surg Int,
Vol: 22 Page: 477-84 June 2006
V. E. Boston
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The aim of this study was to determine the incidence and persistence of neonatal brachial plexus paralysis and evaluated whether its occurrence could be predicted by maternal characteristics or partographic analysis in a large cohort of recent cases
Abstract:
OBJECTIVE: Brachial plexus paralysis is a serious form of neonatal morbidity. We determined its incidence and persistence of disability and evaluated whether its occurrence could be predicted by maternal characteristics or partographic analysis in a large cohort of recent cases. STUDY DESIGN: During the years 1994 through 1998, all infants with neonatal evidence of obstetric brachial more...
International Classification:
Certain conditions originating in the perinatal period - brachial plexus paralysis
Categories:
maternal characteristics or partographic analysis; -neonatal brachial plexus paralysis
Geography:
Republic of Ireland
Am J Obstet Gynecol,
Vol: 187 Page: 1209-12 November 2002
V. Donnelly; A. Foran; J. Murphy; P. McParland; D. Keane; C. O'Herlihy
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