Irish Child Health Database - Peer Reviewed Papers
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Infant, Newborn
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This study reported on babies living with mothers while they are incarcerated
Abstract:
In the Irish Prison service prison is not deemed suitable for babes. Rarely are mothers separated from their children in Ireland as they get temporary release renewed weekly to keep her at home with her baby. The governor explained the system of the prison which I detail below. The women's prison is now known as the Dochas Centre meaning hope, named so by the women themselves. We found more...
International Classification:
Other - incarcerated babies
Categories:
incarcerated babies
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 327-8 January 2007
F. Enright; T. Boyle; J. Murphy
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This article discusses the national neonatal transport programme
Abstract:
Calling all neonatal staff: the National Neonatal Transport Programme is anxious to bring its education programme to as many professionals as possible, writes Patricia Healy. more...
Geography:
Republic of Ireland
World of Irish Nursing,
Vol: 12 Page: 21-22 2004
P. Healy
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This article discusses Belfast's new centralised maternity hospital
Abstract:
Two Belfast Trusts are involved in consultation over the siting of the new centralised maternity hospital. Their proposals have shaped a major consultation document. more...
Geography:
Northern Ireland
RCM Midwives,
2003
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This study aimed to explore a benchmarking comparison survey of regional neonatal units
Abstract:
There are currently eight regional neonatal units in Ireland; three in Dublin and one each in Cork, Limerick, Galway, Drogheda and Waterford. Previous studies have shown a significant variation in the provision of care and services between such units. In July 2005, a postal questionnaire was distributed to a focus group of staff in the eight regional units. The objective was to identify more...
International Classification:
Practice/knowledge - regional neonatal units
Categories:
regional neonatal units
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 429-30 April 2007
L. Hickey; C. Owens; T. Clarke
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The article discusses breast milk and the role Irish hospitals have to play in helping mothers to get started.
Abstract:
With no better start for a baby than breast milk Irish hospitals have a part to play in helping mothers to get started. more...
Geography:
Republic of Ireland
World of Irish Nursing & Midwifery,
Vol: 16 Page: 53-54 2008
J. McCarthy
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This article discusses how a better understanding of the beliefs of Muslim patients will aid healthcare workers to provide optimal care for them
Abstract:
An understanding of the beliefs of Muslim patients with aid healthcare workers to provide optimal care for them, writes Dr Abdul Mughees. more...
Geography:
Republic of Ireland
World of Irish Nursing & Midwifery,
Vol: 14 Page: 24-25 2006
A. Mughees
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This case report discusses bilateral serous retinal detachments following diode laser treatment for retinopathy of prematurity
International Classification:
Diseases of the eye and adnexa - Report
Categories:
retinopathy of prematurity
Geography:
Republic of Ireland
Arch Ophthalmol,
Vol: 121 Page: 129-30 January 2003
A. Mulvihill; B. Lanigan; M. O'Keefe
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The aim of this study was to determine the effect of birth order on the risk of perinatal death in twin pregnancies
International Classification:
Pregnancy, childbirth and the puerperium - perinatal death in twin pregnancies
Categories:
perinatal death in twin pregnancies
Geography:
the United Kingdom
BMJ: British Medical Journal,
Vol: 334 Page: 576-578 2007
G. C. Smith; K. M. Fleming; I. R. White
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The aim of this study was to examine the prevalence of birth cleft lip and palate in Northern Ireland for the 20-year period 1981 to 2000, to determine the pattern of prevalence, and to report the proportion of different cleft types and sex distribution
Abstract:
OBJECTIVE: The prevalence of cleft lip and/or palate (CL/P) in Northern Ireland (NI) was last reported for 1980 through 1990. This study was undertaken to update the prevalence of CL/P in NI for the 20-year period 1981 to 2000, to determine the pattern of prevalence, and to report the proportion of different cleft types and sex distribution. DESIGN: Retrospective, population-based more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Cleft lip and cleft palate - Cleft lip and/or palate
Categories:
birth cleft lip; cleft palate
Geography:
Northern Ireland
Cleft Palate Craniofac J,
Vol: 45 Page: 141-7 March 2008
T. A. Gregg; A. G. Leonard; C. Hayden; K. E. Howard; C. F. Coyle
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The aim of this study was to examine the incidence and outcome of birth-associated femoral fractures
Abstract:
Femoral fractures resulting from birth injuries are rare. The authors undertook a study to assess their incidence and outcome. Seven patients from a total of 55,296 live births suffered 8 femoral fractures (incidence 0.13 per 1,000 live births). Twin pregnancies, breech presentations, prematurity, and disuse osteoporosis were associated with the occurrence of a fracture. The typical more...
International Classification:
Injury, poisoning and certain other consequences of external causes - femoral fractures
Categories:
birth-associated femoral fractures
Geography:
Republic of Ireland
J Pediatr Orthop,
Vol: 22 Page: 27-30 2002 Jan-Feb
S. Morris; N. Cassidy; M. Stephens; D. McCormack; F. McManus
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The aim of this study was to examine trends in birth-weights in the Rotunda hospital in primiparous women over the 20th century
Abstract:
We investigated the trend in birth-weights in the Rotunda hospital in primiparous women over the 20th century. There was a significant increase in birth-weight particularly in the latter third of the century. In light of these findings we believe that new approaches to the management of labour in primiparous mothers be developed. more...
International Classification:
Growth and development
Categories:
birth-weights
Geography:
Republic of Ireland
Ir Med J,
Vol: 98 Page: 6-7 January 2005
G. Connolly; Z. M. Shuhai; P. McKenna; M. Geary
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This article discusses blood loss, replacement and belief among Jehovah's Witnesses
Geography:
Northern Ireland
RCM Midwives,
Vol: 10 Page: 72-5 February 2007
S. Porter
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This article discusses the bronchoalveolar lavage and tracheal aspirate for assessing airway inflammation in children
Geography:
Northern Ireland
Am J Respir Crit Care Med,
Vol: 162 Page: S15-7 August 2000
M. D. Shields; J. Riedler
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This article discusses the role of Calcium and Vitamin D in normal growth and development as well as maintenance of the skeleton
Abstract:
Calcium is required for normal growth and development as well as maintenance of the skeleton. Vitamin D is also essential for intestinal calcium absorption and plays a central role in maintaining calcium homeostasis and skeletal integrity. In addition, both micronutrients have important roles in non-skeletal-related physiological processes. Of concern, significant proportions of some more...
Geography:
Republic of Ireland
Novartis Found Symp,
Vol: 282 Page: 123-38; discussion 138-42, 212-8 2007
K. D. Cashman
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This case report discusses how the classic metaphyseal lesion may occur following simple lower segment caesarean section
Abstract:
BACKGROUND: Classic metaphyseal lesion (CML) is the term given to a fracture that most often occurs in the posteromedial aspect of the distal femur, proximal tibia, distal tibia, and proximal humerus in infants; this finding is strongly associated with non-accidental injury. OBJECTIVE: To demonstrate that the CML may occur following simple lower segment caesarean section (LSCS). more...
International Classification:
Pregnancy, childbirth and the puerperium
Categories:
metaphyseal lesion
Geography:
Republic of Ireland
Pediatr Radiol,
Vol: 37 Page: 488-91 May 2007
A. O'Connell; V. B. Donoghue
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The aim of this study was to examine the candideamia in an Irish tertiary referral hospital, epidemiology and prognostic factors
Abstract:
There were two parts to this study. Part 1 evaluated the epidemiology of Candida bloodstream isolates within the Southern Health Board (SHB) of Ireland from 1992 to 2003 by retrospective surveillance of all such isolates of patients reported from SHB hospitals to our laboratory database during that period. Part 2 reviewed candidaemia cases occurring in Cork University Hospital (CUH) more...
International Classification:
Fungi - Candideamia
Categories:
Candideamia
Geography:
Republic of Ireland
Mycoses,
Vol: 48 Page: 251-9 July 2005
T. W. Boo; B. O'Reilly; J. O'Leary; B. Cryan
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This study described the presenting features, investigations, treatment and outcome of a series of patients with capillary haemangioma of the eyelids and orbit.
Abstract:
PURPOSE: To describe the presenting features, investigations, treatment and outcome of a series of patients with capillary haemangioma of the eyelids and orbit. METHODS: A retrospective analysis of 21 patients, presenting between the years 1985 and 2000. Effectiveness of treatment was determined by final visual acuity and cosmetic result. RESULTS: Lesions were more common in females and more...
International Classification:
Neoplasms - Benign neoplasms - haemangioma
Categories:
capillary haemangioma of the eyelids and orbit
Geography:
Republic of Ireland
Acta Ophthalmol Scand,
Vol: 81 Page: 294-8 June 2003
M. O'Keefe; B. Lanigan; S. A. Byrne
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The aim of this study was to examine the epidemiology of carbon monoxide poisoning in Ireland, using Hospital Inpatient Enquiry (HIPE) data, Mortality data and data from the National Poisons Information Centre
Abstract:
Carbon monoxide (CO) poisoning remains a common preventable cause of morbidity and mortality from poisoning worldwide. Common environmental sources include motor vehicle exhaust, faulty kerosene or gas heaters used in unventilated rooms, and fireplaces with blocked flues. This paper describes the epidemiology of CO poisoning in Ireland, using Hospital Inpatient Enquiry (HIPE) data, more...
International Classification:
Injury, poisoning and certain other consequences of external causes - poisoning
Categories:
carbon monoxide poisoning
Geography:
Republic of Ireland
Ir Med J,
Vol: 96 Page: 83-6 March 2003
D. Crowley; E. Scallan; J. Herbert; A. Staines; B. Herity; J. Tracey
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These case reports discuss two cases of cardiac diverticulum with pericardial effusion: treated by in-utero pericardiocentesis and a review of the literature
Abstract:
Congenital cardiac diverticula are rare abnormalities that may occur as isolated malformations. They are often associated with pericardial effusions, which may cause both pulmonary hypoplasia and progressive fetal hydrops. Few cases are reported in fetal life. Mount Sinai Hospital, Toronto, has previously reported two cases of cardiac diverticula complicated with pericardial effusion more...
International Classification:
Certain conditions originating in the perinatal period - Report
Categories:
in-utero pericardiocentesis
Geography:
Republic of Ireland
Ultrasound Obstet Gynecol,
Vol: 25 Page: 401-4 April 2005
F. M. McAuliffe; L. K. Hornberger; J. Johnson; D. Chitayat; G. Ryan
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The aim of this study was to investigate umbilical artery serum levels of cardiac troponin I, a sensitive and specific marker of myocardial necrosis, and N-terminal pro-brain natriuretic peptide, a sensitive marker of left ventricular dysfunction
Abstract:
The use of continuous fetal heart rate (FHR) recordings to monitor fetal well-being during labor is standard clinical practice in developed countries. Little is known about the relationship, if any, that exists between these FHR abnormalities and the fetal cardiac musculature and function. The aim of this study was to investigate umbilical artery serum levels of cardiac troponin I, a more...
International Classification:
Diseases of the circulatory system - Other forms of heart disease - left ventricular dysfunction
Categories:
left ventricular dysfunction
Geography:
Republic of Ireland
Pediatr Cardiol,
Vol: 22 Page: 393-6 2001 Sep-Oct
S. M. Fleming; T. O'Gorman; L. O'Byrne; H. Grimes; K. M. Daly; J. J. Morrison
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This study examined the range of cTnT and NTpBNP in preterm infants, correlate NTpBNP and cTnT with echocardiographic markers of cardiac function and assess the influence of antenatal and postnatal factors on these biochemical markers
Abstract:
BACKGROUND: Cardiovascular compromise is increasingly recognized in preterm infants. Currently, echocardiography is the best tool to assess myocardial contractility and guide management. Elevated levels of cardiac troponin T (cTnT) and N-terminal-pro-B type natriuretic peptide (NTpBNP) are associated with poor myocardial contractility and low cardiac output in adults. OBJECTIVE: To more...
International Classification:
Pregnancy, childbirth and the puerperium - cardiac function in preterm infants
Categories:
cardiac function
Geography:
Republic of Ireland
J Perinatol,
Vol: 28 Page: 482-6 July 2008
A. El-Khuffash; P. G. Davis; K. Walsh; E. J. Molloy
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The aim of the study was to examine the cardiomyopathy and cardiomegaly in stillborn infants of diabetic mothers
Abstract:
To report the incidence of cardiomegaly in stillborn normally formed infants of mothers with diabetes mellitus. This is a retrospective study with institutional ethics approval. The presence of cardiomegaly was recorded in stillborn infants of diabetic mothers (N = 27) and compared with that recorded in stillborn large-for-gestational age (LGA > 90th percentile, n = 18) and stillborn more...
International Classification:
Pregnancy, childbirth and the puerperium
Geography:
Republic of Ireland
Pediatr Dev Pathol,
Vol: 11 Page: 10-4 2008 Jan-Feb
N. E. Russell; P. Holloway; S. Quinn; M. Foley; P. Kelehan; F. M. McAuliffe
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This article discusses early chronic lung disease
Geography:
Republic of Ireland
Paediatr Respir Rev,
Vol: 3 Page: 162, 164-5 June 2002
D. G. Sweet; H. L. Halliday; J. A. Warner
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The aim of this study was to examine the association of particulate pollution (black smoke) and temperature with age-standardized daily mortality rates over 17 years in Dublin,
Abstract:
Air pollution exposure studies in the past decade have focused on acute (days) or long-term (years) effects. We present an analysis of medium-term (weeks to months) exposure effects of particulate pollution and temperature. We assessed the associations of particulate pollution (black smoke) and temperature with age-standardized daily mortality rates over 17 years in Dublin, Ireland, more...
International Classification:
Other - pollution
Categories:
pollution
Geography:
Republic of Ireland
Environ Health Perspect,
Vol: 112 Page: 179-85 February 2004
P. G. Goodman; D. W. Dockery; L. Clancy
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The aim of this study was to investigate the expression of cell-adhesion molecules fibroblast growth factors, & fibroblast growth factors receptors in ganglionic and aganglionic segments of Hirschsprung's disease
Abstract:
Hirschsprung's disease (HD) is characterised by the absence of ganglion cells and the presence of hypertrophic nerve trunks in the distal bowel. It has been suggested that aganglionosis may be caused by failure of differentiation as a result of microenvironmental change after neuronal migration has occurred. Recently, it was reported that cell-adhesion molecules (CAMs) and fibroblast more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease
Categories:
cell-adhesion molecules & fibroblast growth factors signalling; -Hirschsprung's disease
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 17 Page: 299-303 May 2001
A. Yoneda; Y. Wang; D. S. O'Briain; P. Puri
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The aim of this study was to measure central corneal thickness in premature infants over a (up to) nine week period until term was reached
Abstract:
BACKGROUND: Central corneal thickness is significantly greater in full-term infants than in adults. Very little is known about corneal thickness in premature infants. METHODS: Measurements of central corneal thickness and horizontal corneal diameter were carried out in 35 premature babies (70 eyes) undergoing screening for retinopathy of prematurity. Initial measurements were taken at more...
International Classification:
Other - corneal thickness
Categories:
corneal thickness
Geography:
Republic of Ireland
Acta Ophthalmol Scand,
Vol: 83 Page: 751-3 December 2005
C. Kirwan; M. O'Keefe; S. Fitzsimon
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This study reviewed central venous access devices in children with congenital coagulation disorders to assess complications and long-term outcomes
Abstract:
Reliable venous access is essential to facilitate the administration of prophylactic factor concentrate or blood products in children with congenital coagulation disorders and immune tolerance therapy (ITT) regimens in those who develop high responding inhibitors. Poor venous access is even more problematic in very young children, the vast majority of whom will require the insertion of more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - congenital coagulation disorders
Categories:
congenital coagulation disorders
Geography:
Republic of Ireland and the United Kingdom
Br J Haematol,
Vol: 110 Page: 461-8 August 2000
C. McMahon; J. Smith; K. Khair; R. Liesner; I. M. Hann; O. P. Smith
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These case reports discuss two cases of spastic diplegia of prematurity comorbid with juvenile onset bipolar disorder, which highlight some of the diagnostic difficulties in these cases
Abstract:
Cerebral palsy refers to a heterogeneous group of congenital and early acquired brain disorders. Children with cerebral palsy and other brain disorders have an increased rate of psychiatric disorder. The pattern of disorder is not particularly distinctive and no specific association has been found. We report two cases of spastic diplegia of prematurity comorbid with juvenile onset more...
International Classification:
Diseases of the nervous system - Report
Categories:
spastic diplegia
Geography:
Republic of Ireland
Eur Child Adolesc Psychiatry,
Vol: 11 Page: 134-7 June 2002
C. Craven; A. James; M. Murphy
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[Read]
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This study aimed to describe the method of compilation of the Northern Ireland Cerebral Palsy Register (NICPR) and outlines the epidemiology of cerebral palsy (CP) in Northern Ireland in 1981--93
Abstract:
This paper describes the method of compilation of the Northern Ireland Cerebral Palsy Register (NICPR) and outlines the epidemiology of cerebral palsy (CP) in Northern Ireland in 1981--93 based on an analysis of 784 cases. Multiple and overlapping sources of notification were used to compile the NICPR. Each case was followed up with a standardised assessment completed at age 5 years and more...
International Classification:
Effectiveness of measurement tool - compilation of the Northern Ireland Cerebral Palsy Register
Categories:
method of compilation of the Northern Ireland Cerebral Palsy Register
Geography:
Northern Ireland
Paediatr Perinat Epidemiol,
Vol: 15 Page: 278-86 July 2001
J. Parkes; H. Dolk; N. Hill; S. Pattenden
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[Read]
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The aim of this study was to examine impact of legal change on the practice of involving birth fathers in the stepfamily adoption decisions relating to their children
Abstract:
The majority of domestic adoption applications in the Republic of Ireland today concern the adoption of children into their stepfamilies. These adoptions are processed under the Adoption Act 1952 and the adoption severs connections with the child's non-custodial birth parent, usually the birth father. Birth fathers had no legal entitlement to inclusion in any decision about the proposed more...
International Classification:
Adoption
Categories:
adoption
Geography:
Republic of Ireland
Adoption & Fostering,
Vol: 28 Page: 59-69 2004
C. Loftus
[Preview]
[Read]
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The aim of this study was to examine trends in congenital abdominal wall defects in the eastern region of Ireland
Abstract:
In the past six years, there have been reports from abroad of an unexplained rise in the birth prevalence rate of the congenital abdominal wall defect gastroschisis, while rates for the macroscopically similar anomaly omphalocoele have remained stable. The Dublin EUROCAT Registry of congenital anomalies monitors trends in the birth prevalence of birth defects in the eastern region of more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - congenital abdominal wall defects
Categories:
congenital abdominal wall defects
Geography:
Republic of Ireland
Ir Med J,
Vol: 95 Page: 236, 238 September 2002
R. McDonnell; V. Delany; P. Dack; H. Johnson
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[Read]
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The aim of this study was to examine 51 environmental and food E. sakazakii isolates and 6 E. sakazakii type strains
Abstract:
Enterobacter sakazakii has emerged as a rare cause of neonatal meningitis, septicemia and enterocolitis. Contaminated infant milk formula (IMF) has been identified as one infection route. A small number of clinical outbreaks have been epidemiologically linked to IMF contaminated post-pasteurization during manufacture and/or mishandled when reconstituted. Currently no agreed standardized more...
International Classification:
Bacterium - Enterobacter sakazakii
Categories:
E. sakazakii type strains
Geography:
Republic of Ireland
Int J Food Microbiol,
Vol: 110 Page: 127-34 July 2006
D. Drudy; M. O'Rourke; M. Murphy; N. R. Mullane; R. O'Mahony; L. Kelly; M. Fischer; S. Sanjaq; P. Shannon; P. Wall; M. O'Mahony; P. Whyte; S. Fanning
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This article discusses characterization of changes in blood vessel width and tortuosity in retinopathy of prematurity using image analysis
Abstract:
Many retinal diseases are characterised by changes to retinal vessels. For example, a common condition associated with retinopathy of prematurity (ROP) is so-called plus disease, characterised by increased vascular dilation and tortuosity. This paper presents a general technique for segmenting out vascular structures in retinal images, and characterising the segmented blood vessels. The more...
Geography:
Republic of Ireland
Med Image Anal,
Vol: 6 Page: 407-29 December 2002
C. Heneghan; J. Flynn; M. O'Keefe; M. Cahill
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[Read]
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The aim of this review was to determine the efficacy and safety of chest physiotherapy in infants aged less than 24 months old with acute bronchiolitis
Abstract:
BACKGROUND: Acute bronchiolitis is the leading cause of medical emergencies during winter in children younger than two years of age. Chest physiotherapy is thought to assist infants in the clearance of secretions and to decrease ventilatory effort. OBJECTIVES: To determine the efficacy and safety of chest physiotherapy in infants aged less than 24 months old with acute bronchiolitis. more...
International Classification:
Systematic Review
Categories:
chest physiotherapy in infants
Geography:
Systematic Review
Cochrane Database Syst Rev,
2007
C. Perrotta; Z. Ortiz; M. Roque
[Preview]
[Read]
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This article discusses immunisation uptake rates
Abstract:
While the latest national immunisation uptake rates show a promising rise, there is still a long way to go in preventing disease outbreaks. more...
Geography:
Republic of Ireland
World of Irish Nursing & Midwifery,
Vol: 13 Page: 45-45 2005
T. Horan
[Preview]
[Read]
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The aim of this study was to examine the hypothesis which predicts that infusions of information into an environment will lead to knowledge gain by groups with higher socioeconomic status at rates that outpace the knowledge gain of lower SES groups
Abstract:
The knowledge gap hypothesis predicts that infusions of information into an environment will lead to knowledge gain by groups with higher socioeconomic status (SES) at rates that outpace the knowledge gain of lower SES groups, leading to a growing relative gap between them. Four information source variables were examined in the present study: education, baby care experience, friend and more...
International Classification:
Education
Categories:
education; inequalities
Geography:
International
J Health Commun,
Vol: 3 Page: 29-51 1998 Jan-Mar
C. Gaziano; J. O'Leary
[Preview]
[Read]
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The aim of this study was to undertake an analysis of the incidence and survival data for cancers diagnosed in children under 15 years of age in the Republic of Ireland during 1994-2000 and the longer term mortality trends
Abstract:
BACKGROUND: Population-based studies of childhood cancer incidence, survival and mortality make an important contribution to monitoring the successful implementation of new treatment guidelines and to understanding the epidemiology of these diseases. METHODS: We analysed incidence and survival data for cancers diagnosed in children under 15 years of age in the Republic of Ireland during more...
International Classification:
Neoplasm - cancer
Categories:
cancer
Geography:
Republic of Ireland
Arch Dis Child,
Vol: 92 Page: 890-7 October 2007
M. Stack; P. M. Walsh; H. Comber; C. A. Ryan; P. O'Lorcain
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[Read]
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This case report discusses a case of choanal atresia - a recurrent feature of foetal carbimazole syndrome
Abstract:
Choanal atresia is described as a feature of several congenital anomaly phenotypes. Most cases of choanal atresia arises as an isolated clinical finding. In utero exposure to carbimazole for maternal hyperthyroidism has been reported in five cases of choanal atresia. We report another instance of this teratogenic cause of choanal atresia. Maternal drug history is an important aspect of more...
International Classification:
Syndrome
Categories:
Foetal carbimazole syndrome
Geography:
Republic of Ireland
Clin Otolaryngol,
Vol: 30 Page: 375-7 August 2005
A. K. Myers; W. Reardon
[Preview]
[Read]
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The aim of this study was to examine the intermediates of choline oxidation in maternal and umbilical cord plasma and to determine the relations between this pathway and folate-dependent homocysteine remethylation
Abstract:
BACKGROUND: Little is known about the interactions between choline and folate and homocysteine metabolism during pregnancy despite the facts that pregnancy places considerable stress on maternal folate and choline stores and that choline is a critical nutrient for the fetus. Choline, via betaine, is an important folate-independent source of methyl groups for remethylating homocysteine more...
International Classification:
Other - Folate and folic acid
Categories:
folate-dependent homocysteine remethylation
Geography:
Republic of Ireland and the United Kingdom
American Journal of Clinical Nutrition,
Vol: 82 Page: 836-842 2005
A. M. Molloy; J. L. Mills; C. Cox; S. F. Daly; M. Conley; L. C. Brody; P. N. Kirke; J. M. Scott; P. M. Ueland
[Preview]
[Read]
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The aim of this study was to determine the effects of chorioamnionitis and antenatal corticosteroids on matrix metalloproteinase-8 (MMP-8) concentrations in bronchoalveolar lavage (BAL) fluid from preterm babies in the first week of life
Abstract:
OBJECTIVE: To determine the effects of chorioamnionitis and antenatal corticosteroids on matrix metalloproteinase-8 (MMP-8) concentrations in bronchoalveolar lavage (BAL) fluid from preterm babies in the first week of life. DESIGN: Prospective observational study. SETTING: Regional neonatal intensive care unit. PATIENTS: Thirty five ventilated preterm babies < 33 weeks gestation, seven more...
International Classification:
Pregnancy, childbirth and the puerperium - chorioamnionitis
Categories:
chorioamnionitis;
Geography:
Northern Ireland
Arch Dis Child Fetal Neonatal Ed,
Vol: 89 Page: F61-4 January 2004
A. E. Curley; D. G. Sweet; K. J. MacMahon; C. M. O'Connor; H. L. Halliday
[Preview]
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The aim of this study was to identify and investigate care for children born, over a 17-year period (1980-1996), with cleft lip and/or palate (CL/P) in the Western Health Board region of Ireland
Abstract:
The aim of this study was to identify and investigate care for children born, over a 17-year period (1980-1996), with cleft lip and/or palate (CL/P) in the Western Health Board region of Ireland. One hundred and six cleft-affected children were identified. The incidence was 1.14 per thousand (1:871) live births. Epidemiological findings in relation to cleft type, gender, family history, more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Cleft lip and/or palate
Categories:
Cleft lip and/or palate
Geography:
Republic of Ireland
Spec Care Dentist,
Vol: 20 Page: 143-6 2000 Jul-Aug
A. R. Hewson; C. M. McNamara
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[Read]
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This case report discusses a 1-day-old baby girl with a cleft of the secondary palate and a soft tissue band connecting the upper and lower jaws and preventing mouth opening
Abstract:
OBJECTIVE: A 1-day-old baby girl with a cleft of the secondary palate and a soft tissue band connecting the upper and lower jaws and preventing mouth opening was referred to the cleft lip and palate team by her pediatrician. This case represents a further example of an interesting but rare anomaly known as congenital alveolar synechia syndrome that requires early management to allow more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Report
Categories:
cleft palate
Geography:
Republic of Ireland
Cleft Palate Craniofac J,
Vol: 41 Page: 206-7 March 2004
S. M. Murphy; S. Rea; E. McGovern; P. Fleming; D. Orr
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The aim of this study was to examine the clinical and immunological risk factors associated with Haemophilus influenzae type b conjugate vaccine failure in childhood
Abstract:
Haemophilus influenzae type b (Hib) conjugate vaccines have proved extremely efficacious in healthy children. True Hib vaccine failures are rare. Hib conjugate vaccines were introduced for routine immunization in the United Kingdom and the Republic of Ireland in 1992. Coincident with this, active prospective and national surveillance via pediatricians, microbiologists, and public health more...
International Classification:
Bacterium - Haemophilus influenzae type b
Categories:
Haemophilus influenzae type b
Geography:
Republic of Ireland and the United Kingdom
Clin Infect Dis,
Vol: 31 Page: 973-80 October 2000
P. T. Heath; R. Booy; H. Griffiths; E. Clutterbuck; H. J. Azzopardi; M. P. Slack; J. Fogarty; A. C. Moloney; E. R. Moxon
[Preview]
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This case report discusses clinical and molecular findings in IPEX syndrome
Abstract:
IPEX (immunodysregulation, polyendocrinopathy, enteropathy, X linked syndrome) is a rare disorder which usually results in death in early infancy or childhood. Clinical awareness remains the cornerstone of diagnosis, and provided that the diagnosis is entertained, mutation analysis for FOXP3 gene mutations can be confirmatory. Two new patients in whom IPEX was diagnosed retrospectively more...
International Classification:
Syndrome
Categories:
IPEX syndrome
Geography:
Republic of Ireland
Arch Dis Child,
Vol: 91 Page: 63-4 January 2006
A. K. Myers; L. Perroni; C. Costigan; W. Reardon
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The aim of this study was to examine the correlates of Cerebal Palsy in a population sample and compare clinical findings with information available from MRI brain studies
Abstract:
CONTEXT: Magnetic resonance imaging (MRI) findings have been reported for specific clinical cerebral palsy (CP) subgroups or lesion types but not in a large population of children with all CP subtypes. Further information about the causes of CP could help identify preventive strategies. OBJECTIVE: To investigate the correlates of CP in a population sample and compare clinical findings more...
International Classification:
Diseases of the nervous system - Cerebral palsy and other paralytic syndromes - cerebral palsy
Categories:
cerebral palsy
Geography:
International
Jama,
Vol: 296 Page: 1602-8 October 2006
M. Bax; C. Tydeman; O. Flodmark
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This study examined a generic adenovirus nested polymerase chain amplification assay designed to be capable of detecting all respiratory adenoviruses.
Abstract:
BACKGROUND: respiratory adenoviruses are common, often resulting in serious sporadic and epidemic infections and impaired immunity can dramatically increase their severity. They are now thought capable of establishing latency. Diagnosis by culture is slow while direct antigen detection by immunofluorescence lacks sensitivity. Molecular diagnosis can be both rapid and sensitive but the more...
International Classification:
Diagnostic tool laboratory - adenovirus
Categories:
Dimercaptosuccinic acid scan (DMSA); Magnetic resonance imaging (MRI)
Geography:
Northern Ireland
J Clin Virol,
Vol: 26 Page: 331-8 April 2003
S. Mitchell; H. J. O'Neill; G. M. Ong; S. Christie; P. Duprex; D. E. Wyatt; C. McCaughey; V. J. Armstrong; S. Feeney; L. Metwally; P. V. Coyle
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The aim of this study was to investigate use of video recordings of newborn infants to determine colour and oxygen saturation
Abstract:
OBJECTIVE: Use of video recordings of newborn infants to determine: (1) if clinicians agreed whether infants were pink; and (2) the pulse oximeter oxygen saturation (Spo(2)) at which infants first looked pink. METHODS: Selected clips from video recordings of infants taken immediately after delivery were shown to medical and nursing staff. The infants received varying degrees of more...
International Classification:
Health service provision
Categories:
video recordings as a monitoring facility
Geography:
Republic of Ireland
Arch Dis Child Fetal Neonatal Ed,
Vol: 92 Page: F465-7 November 2007
C. P. O'Donnell; C. O. Kamlin; P. G. Davis; J. B. Carlin; C. J. Morley
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The aim of this study was to describe the presenting features of type 1 diabetes in a national incident cohort aged under 15 years
Abstract:
OBJECTIVE: To identify the presenting features of type 1 diabetes in a national incident cohort aged under 15 yr, the duration of symptoms, the occurrence of diabetic ketoacidosis (DKA) at presentation, and the frequency of a family history of diabetes. METHODS: A prospective study was undertaken of incident cases of type 1 diabetes using an active monthly reporting card system from more...
International Classification:
Endocrine, nutritional and metabolic diseases - Diabetes mellitus - type 1 diabetes mellitus
Categories:
type 1 diabetes; diabetic ketoacidosis
Geography:
Republic of Ireland
Pediatr Diabetes,
Vol: 6 Page: 75-8 June 2005
E. F. Roche; A. Menon; D. Gill; H. Hoey
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The aim of this study was to examine the incidence of late diagnosed developmental dysplasia of the hip requiring surgery in Northern Ireland
Abstract:
PROBLEM: The incidence of late diagnosed developmental dysplasia of the hip requiring surgery in Northern Ireland is high. The reported incidence was 1.14 per 1000 children born during 1983-7. DESIGN: Comparative retrospective study. BACKGROUND AND SETTING: Clinical screening programme in Northern Ireland. Key measure for improvement: Reduced rate of operative intervention in children more...
International Classification:
Congenital malformations and deformations of the musculosketal system - Congenital malformations and deformations of the musculoskeletal system - developmental dysplasia of the hip
Categories:
late diagnosed developmental dysplasia of the hip
Geography:
Northern Ireland
Bmj,
Vol: 324 Page: 1031-3 April 2002
S. L. Maxwell; A. L. Ruiz; K. J. Lappin; A. P. Cosgrove
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This study aimed to describe a combination of an ECG-based classifier system with a novel multi-channel EEG-based classifier system to develop an improved neonatal seizure detection performance
Abstract:
OBJECTIVE: Neonatal seizures are the most common central nervous system disorder in newborn infants. A system that could automatically detect the presence of seizures in neonates would be a significant advance facilitating timely medical intervention. METHODS: A novel method is proposed for the robust detection of neonatal seizures through the combination of simultaneously-recorded more...
International Classification:
Effectiveness of measurement tool - ECG-based classifier system, multi-channel EEG-based
Categories:
ECG-based classifier system; multi-channel EEG-based classifier; neonatal seizure
Geography:
Republic of Ireland
Clin Neurophysiol,
Vol: 118 Page: 1348-59 June 2007
B. R. Greene; G. B. Boylan; R. B. Reilly; P. de Chazal; S. Connolly
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This article comments on: antimicrobial policies in the neonatal units of the United Kingdom and Republic of Ireland
Geography:
Republic of Ireland and the United Kingdom
J Antimicrob Chemother,
Vol: 62 Page: 429-30 August 2008
A. Prendergast; T. Walls; P. Turner; D. Cubitt; J. Hartley; N. Klein; V. Novelli
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