Irish Child Health Database - Peer Reviewed Papers
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This article discusses the first 20 years of the British Paediatric Surveillance Unit
Geography:
England
Arch Dis Child,
Vol: 92 Page: 744-5 September 2007
R. Lynn; E. Ross
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The aim of this study was to examine an annual report on the population of the UK on one specific topic - fertility
Abstract:
The population of the UK is currently growing at its fastest rate since the 1960s, increasing by two and a half per cent between mid-2001 and mid-2006. While life expectancy continues to increase, fertility rates have also been increasing in the last five years and are currently at their highest level since 1980. In addition, international migration has led to the UK population growing more...
International Classification:
Other - fertility
Categories:
fertility
Geography:
the United Kingdom
Popul Trends,
2007 Winter
K. Dunnell
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This article discussed the Children's Cancer and Leukaemia Group guidelines for the diagnosis and management of dysembryoplastic neuroepithelial tumours
Abstract:
Dysembryoplastic neuroepithelial tumours (DNETs) were incorporated into the new World Health Organization classification of brain tumours as part of the group of glioneuronal tumours in 1993. Large series of patients with DNETs and pharmaco-resistant epilepsy have been reported. DNETs are most often located in the temporal lobe, occurring in both mesial and lateral temporal locations. more...
Geography:
Republic of Ireland
Br J Neurosurg,
Vol: 21 Page: 539-49 December 2007
D. F. O'Brien; M. Farrell; N. Delanty; H. Traunecker; R. Perrin; M. D. Smyth; T. S. Park
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This study examined the clinical outcome of pregnancies with non-Rh-D antibody using retrospective case note review.
Abstract:
We assessed the clinical outcome of pregnancies with non-Rh-D antibody in Northern Ireland using retrospective case note review. During the study period (April 1999- March 2000) 186 women with clinically significant antibodies were identified from the records of the antenatal laboratory of the Northern Ireland Blood Transfusion Service. Eighty-five women were included in the study using more...
International Classification:
Pregnancy, childbirth and the puerperium - pregnancies with non-Rh-D antibody
Categories:
pregnancies with non-Rh-D antibody
Geography:
Northern Ireland
Ulster Med J,
Vol: 70 Page: 89-94 November 2001
A. Chandrasekar; K. G. Morris; T. R. Tubman; S. Tharma; W. M. McClelland
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This article discusses continuing decline of autopsies in clinical trials
Geography:
Republic of Ireland
Arch Dis Child Fetal Neonatal Ed,
Vol: 89 Page: F198-9 May 2004
M. McDermott
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The aim of this study was to determine the continuing effectiveness of active management of labor, a protocol that involves early detection and correction of dystocia with oxytocin in spontaneous cephalic nulliparous labor
Abstract:
OBJECTIVE: The purpose of this study was to determine the continuing effectiveness of active management of labor, a protocol that involves early detection and correction of dystocia with oxytocin in spontaneous cephalic nulliparous labor, by analysis of the contribution of this cohort to a doubled overall nulliparous cesarean delivery rate. STUDY DESIGN: This was a retrospective more...
International Classification:
Pregnancy, childbirth and the puerperium - active management of labor
Categories:
active management of labor
Geography:
Republic of Ireland
Am J Obstet Gynecol,
Vol: 191 Page: 891-5 September 2004
M. E. Foley; M. Alarab; L. Daly; D. Keane; A. Rath; C. O'Herlihy
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The aim of this study was to examine the epidemiological factors associated with Sudden Infant Death Syndrome to give a general profile of SID cases occurring in Ireland between the years 1993 to 1997
Abstract:
This paper examines some epidemiological factors associated with SIDS to give a general profile of SIDS cases occurring in Ireland between the years 1993 to 1997. There has been a dramatic decrease in the incidence of the Sudden Infant Death Syndrome (SIDS) in the Republic of Ireland in the last decade from an average rate of 2.2/1000 live-births in the 1980s to 0.8/1000 live-births in more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
sudden infant death syndrome
Geography:
Republic of Ireland
Ir Med J,
Vol: 93 Page: 264-8 December 2000
M. Mehanni; A. Cullen; B. Kiberd; M. McDonnell; M. O'Regan; T. Matthews
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The aim of this study was to examine the delivery of the first babies conceived using testicular sperm in Northern Ireland
International Classification:
Other - testicular sperm
Categories:
testicular sperm
Geography:
Northern Ireland
Ulster Med J,
Vol: 69 Page: 165-7 November 2000
E. K. Steele; J. A. McNally; S. E. Lewis; N. McClure
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The aim of this study was to examine the effect of frequency band on quantitative EEG measures in neonates with hypoxic-ischaemic encephalopathy
Abstract:
The effect of frequency ranges on three quantitative EEG measures as related to neurodevelopmental outcome at 12-24 months is reported here. Thirteen EEG records from term neonates with moderate hypoxic-ischaemic encephalopathy (HIE) were analyzed. The spectral entropy, spectral edge frequency and relative power were calculated for each EEG channel. 4 separate frequency ranges were more...
International Classification:
Other - EEG measures
Categories:
hypoxic-ischaemic encephalopathy
Geography:
Republic of Ireland
Conf Proc IEEE Eng Med Biol Soc,
Vol: 2007 Page: 717-21 2007
O. M. Doyle; B. R. Greene; D. M. Murray; L. Marnane; G. Lightbody; G. B. Boylan
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This article discusses postnatal corticosteroids, exploring both beneficial and harmful effects.
Abstract:
Single courses of prenatal corticosteroids have many beneficial effects including reduction in respiratory distress syndrome, intraventricular hemorrhage and neonatal mortality. Postnatal corticosteroids, however, have both beneficial and harmful effects. The beneficial effects include shortened time on the ventilator and a reduction in chronic lung disease. Dexamethasone treatment more...
Geography:
Northern Ireland
J Perinat Med,
Vol: 29 Page: 281-5 2001
H. L. Halliday
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The aim of this study was to assess whether the coagulation activation associated with pre-eclamptic pregnancy spills over into the fetal circulation ad affects the fetal haemostatic system
International Classification:
Pregnancy, childbirth and the puerperium
Categories:
pre-eclamptic pregnancy; coagulation activation; fetal haemostatic system
Geography:
Republic of Ireland
Thromb Res,
Vol: 99 Page: 567-70 September 2000
J. R. Higgins; J. Bonnar; L. A. Norris; M. R. Darling; J. J. Walshe
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The aim of this study was to analyse the incidence, aetiology and management of live born cases of hydrops fetalis in a Regional Perinatal Centre
Abstract:
OBJECTIVES: To analyse the incidence, aetiology and management of live born cases of hydrops fetalis in a Regional Perinatal Centre. METHODS: We reviewed 35 cases of hydrops delivered over a six year period. RESULTS: Non-immune hydrops accounted for 80% of the cases and the majority of babies required Level 1 intensive care. The mortality rate was 40%. CONCLUSION: The pattern of hydrops more...
International Classification:
Certain conditions originating in the perinatal period - Haemorrhagic and haematological disorders of fetus and newborn - hydrops fetalis
Categories:
hydrops fetalis
Geography:
Northern Ireland
Ulster Med J,
Vol: 75 Page: 185-6 September 2006
B. Trainor; R. Tubman
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This article discusses vaginal breech delivery
Geography:
Republic of Ireland
Bjog,
Vol: 113 Page: 969-72 August 2006
G. Burke
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The aim of this study was to describe perinatal factors associated with later morbidity among extremely preterm children at 30 months of age
Abstract:
AIMS: To describe perinatal factors associated with later morbidity among extremely preterm children at 30 months of age corrected for prematurity. POPULATION: Of 308 surviving children born at more...
International Classification:
Premature - children
Categories:
extremely preterm children
Geography:
Republic of Ireland and the United Kingdom
Arch Dis Child Fetal Neonatal Ed,
Vol: 90 Page: F134-40 March 2005
N. S. Wood; K. Costeloe; A. T. Gibson; E. M. Hennessy; N. Marlow; A. R. Wilkinson
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The aim of this study was to examine growth outcomes of a geographically defined population of extremely preterm babies.
Abstract:
AIM: To define growth outcomes of a geographically defined population of extremely preterm babies. POPULATION: The EPICure study identified all surviving children in the United Kingdom and Ireland born at < or = 25 weeks 6 days gestation between March and December 1995. Of 308 survivors, 283 (92%) were evaluated at 30 months of age corrected for prematurity. METHODS: Growth was measured more...
International Classification:
Premature - babies
Categories:
growth; preterm babies
Geography:
Republic of Ireland and the United Kingdom
Arch Dis Child Fetal Neonatal Ed,
Vol: 88 Page: F492-500 November 2003
N. S. Wood; K. Costeloe; A. T. Gibson; E. M. Hennessy; N. Marlow; A. R. Wilkinson
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The aim of this study was to assess study growth and blood pressure in extremely preterm children at 6 years of age
Abstract:
BACKGROUND: Preterm children are at risk for reduced growth in early childhood, which may predispose them to later changes in blood pressure (BP). OBJECTIVE: To study growth and BP in extremely preterm (EP) children at age 6 years. METHODS: Children who were born at 25 completed weeks of gestation or less in the United Kingdom and Ireland in 1995 were evaluated when they reached early more...
International Classification:
Premature - children
Categories:
growth; blood pressure
Geography:
Republic of Ireland and the United Kingdom
Arch Dis Child Fetal Neonatal Ed,
Vol: 93 Page: F108-14 March 2008
M. A. Bracewell; E. M. Hennessy; D. Wolke; N. Marlow
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This study examined the outcome for all infants born before 26 weeks of gestation in the United Kingdom and the Republic of Ireland
Abstract:
Objective. To evaluate the outcome for all infants born before 26 weeks of gestation in the United Kingdom and the Republic of Ireland. This report is of survival and complications up until discharge from hospital.
Methodology. A prospective observational study of all births between March 1, 1995 and December 31, 1995 from 20 to 25 weeks of gestation.
Results. A total of 4004 births more...
International Classification:
Premature - infants
Categories:
outcomes for premature infants
Geography:
Republic of Ireland and the United Kingdom
Pediatrics,
Vol: 106 Page: 659-671 2000
K. Costeloe; E. Hennessy; A. T. Gibson; N. Marlow; A. R. Wilkinson
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The aim of this study was to determine non-licensed drug usage in a non-specialised paediatric unit
Abstract:
Children receive many drugs which are either unlicensed or used outside the licensing terms (off-label prescribing). Children are thereby at greater risk of side-effects. We sought to determine non-licensed drug usage in a non-specialised paediatric unit because previous studies had examined only specialised centres. Drug charts were examined prospectively over two months. Items were more...
International Classification:
Drugs - non-licensed use
Categories:
non-licensed drug usage
Geography:
Northern Ireland
Ir Med J,
Vol: 94 Page: 237-40 September 2001
J. S. Craig; C. R. Henderson; F. A. Magee
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The aim of this study was to examine data on infants affected by the haemolytic disease Rhesus D with regard to adverse outcomes and the current routine antenatal prophylactic anti-D programme
Abstract:
It has been suggested that routine antenatal prophylactic anti-D should be introduced for prevention of Rhesus D (RhD) haemolytic disease. Before making changes to the current prevention program it is important, therefore, to have up-to-date data on affected infants. Pregnant women with anti-D antibodies between September 1994 and February 1997 were identified by the Northern Ireland more...
International Classification:
Certain conditions originating in the perinatal period - Haemorrhagic and haematological disorders of fetus and newborn - haemolytic disease Rhesus D
Categories:
haemolytic disease Rhesus D
Geography:
Northern Ireland
Ir Med J,
Vol: 93 Page: 17-8 2000 Jan-Feb
S. Craig; K. Morris; T. Tubman; B. McClure
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This study examined the frequency and outcome of biliary atresia in United Kingdom and Irish children
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Congenital malformations of the digestive system - biliary atresia
Categories:
biliary atresia
Geography:
Republic of Ireland and the United Kingdom
Lancet,
Vol: 355 Page: 25-29 2000 2000 Jan 1
P. J. McKiernan; A. J. Baker; D. A. Kelly
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The aim of this study was to characterises escherichia coli as the principal gram-negative causative agent of sepsis and meningitis in neonates
Abstract:
Escherichia coli is the principal gram-negative causative agent of sepsis and meningitis in neonates. The pathogenesis of meningitis due to E. coli K1 involves mucosal colonization, transcytosis of epithelial cells, survival in the blood stream and eventually invasion of the meninges. The latter two aspects have been well characterized at a molecular level in the last decade. Less is more...
International Classification:
Diseases of the nervous system - Inflammatory diseases of the central nervous system - meningitis
Categories:
escherichia coli; sepsis; meningitis
Geography:
Republic of Ireland
FEMS Microbiol Lett,
Vol: 269 Page: 248-55 April 2007
R. P. Fagan; S. G. Smith
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The aim of this study was to assess the psychosocial consequences for mothers and the developing mother-child relationship of UltraSound, and associations between abduction splinting and maternal psychosocial distress
Abstract:
BACKGROUND: The hip trial aimed to assess clinical effectiveness, economic and psychosocial costs, and benefits of ultrasound imaging (US) compared with conventional clinical assessment alone to guide the management of infants with neonatal hip instability. OBJECTIVE: To report on psychosocial consequences for mothers and the developing mother-child relationship of US, and associations more...
International Classification:
Evaluation of the impact of UltraSound on the developing mother and child relationship
Categories:
maternal psychosocial distress and the mother-child relationship
Geography:
Republic of Ireland and the United Kingdom
Arch Dis Child Fetal Neonatal Ed,
Vol: 90 Page: F17-24 January 2005
F. Gardner; C. Dezateux; D. Elbourne; A. Gray; A. King; A. Quinn
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This article discusses the history of obstetrics in Northern Ireland 1921-1992
Abstract:
In 1921 there was little provision for the care of the pregnant woman in Northern Ireland where there were only two hospitals staffed by specialist obstetricians. The mortality statistics reflected this, the province having the highest maternal mortality and the second highest infant mortality rates in the United Kingdom. There was little progress until the establishment of the National more...
Geography:
Northern Ireland
Ulster Med J,
Vol: 70 Page: 95-101 November 2001
J. F. O'Sullivan
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The aim of this study was to examine hypothalamic-pituitary-thyroid axis in preterm infants; changes in the first 24 hours of postnatal life
Abstract:
The purpose of this study was to measure serum T4, free T4, TSH, T3, rT3, T4 sulfate, and thyroxine binding globulin at four time points within the first 24 h of life (cord and 1, 7, and 24 h) in infants between 24 and 34 wk gestation. The infants were subdivided into gestational age groups: 24-27 wk (n = 22); 28-30 wk (n = 26); and 31-34 wk (n = 24). The TSH surge in the first hour of more...
International Classification:
Premature - infants
Categories:
hypothalamic-pituitary-thyroid axis in preterm infants
Geography:
Republic of Ireland
J Clin Endocrinol Metab,
Vol: 89 Page: 2824-31 June 2004
N. Murphy; R. Hume; H. van Toor; T. G. Matthews; S. A. Ogston; S. Y. Wu; T. J. Visser; F. L. Williams
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The aim of this study was to examine the incidence and impact of increased body mass index on maternal and fetal morbidity in the low-risk primigravid population
Abstract:
OBJECTIVE: To determine the incidence and impact of increased body mass index (BMI) on maternal and fetal morbidity in the low-risk primigravid population. METHODS: This was a prospective study with retrospective analysis of delivery outcome data. All low-risk primigravida who met the inclusion criteria during the recruitment period were approached. BMI was calculated using the formula more...
International Classification:
Pregnancy, childbirth and the puerperium
Categories:
increased body mass index; maternal and fetal morbidity
Geography:
Republic of Ireland
J Matern Fetal Neonatal Med,
Vol: 20 Page: 879-83 December 2007
R. K. Sarkar; S. M. Cooley; J. C. Donnelly; T. Walsh; C. Collins; M. P. Geary
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This study examined the incidence of congenital heart disease diagnosed in the infants presenting to the tertiary referral centre in Belfast.
Abstract:
There is a recognised association between major gastrointestinal (GI) malformations and congenital heart disease (CHD). A retrospective study over 10 years involving 240 infants born with gastrointestinal malformations was conducted in the Royal Belfast Hospital For Sick Children (RBHSC). We felt it was important to look at the incidence of CHD diagnosed in the infants presenting to the more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Congenital malformations of the circulatory system - congenital heart disease
Categories:
congenital heart disease
Geography:
Northern Ireland
Ulster Med J,
Vol: 69 Page: 23-6 May 2000
A. J. Thompson; H. C. Mulholland
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The aim of the study was to examine the intellectual abilities of early-treated individuals with pyridoxine-nonresponsive homocystinuria due to cystathionine beta-synthase deficiency
Abstract:
The pathological sequelae of untreated homocystinuria due to cystathionine beta-synthase deficiency include ectopia lentis, osteoporosis, thromboembolic events and mental retardation. They occur at a significantly higher rate with poorer mental capabilities (mean IQ = 57) in the untreated pyridoxine-nonresponsive individuals. The mental capabilities of 23 pyridoxine-nonresponsive more...
International Classification:
Mental and behavioural disorders - Mental retardation - intellectual abilities
Categories:
intellectual abilities
Geography:
Republic of Ireland
J Inherit Metab Dis,
Vol: 24 Page: 437-47 August 2001
S. Yap; H. Rushe; P. M. Howard; E. R. Naughten
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The aim of this study was to assess the intubating conditions afforded by the McCoy (#1) straight blade laryngoscope with the conventional Miller (#1) blade in neonates and infants
Abstract:
PURPOSE: The McCoy curved blade laryngoscope has been demonstrated to improve view at laryngoscopy in adults. A straight-bladed version of this laryngoscope has recently been introduced into pediatric practice. The objective of this prospective, randomized study was to compare the intubating conditions afforded by the McCoy (#1) straight blade laryngoscope with the conventional Miller more...
International Classification:
Evaluation of the effectiveness of procedures - intubation
Categories:
intubating conditions
Geography:
Republic of Ireland
Can J Anaesth,
Vol: 51 Page: 155-9 February 2004
G. Iohom; R. Franklin; W. Casey; B. Lyons
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This study aimed to explore the standardization of measurement of blood pressure and the detection of hypertension in children and adolescents
Abstract:
Despite the publication of several expert committee guidelines for the measurement of blood pressure (BP) and the diagnosis of hypertension in children and adolescents, it was our perception and clinical experience that there still appeared to be a general lack of standardisation of BP measurement techniques and little consensus on the criteria for diagnosing hypertension. To more...
International Classification:
Practice/knowledge - blood pressure
Categories:
blood pressure;
Geography:
Republic of Ireland and the United Kingdom
J Hum Hypertens,
Vol: 15 Page: 419-23 June 2001
G. Y. Lip; M. Beevers; D. G. Beevers; M. J. Dillon
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This article discusses the launch of the Ireland-Northern Ireland-National Cancer Institute Cancer Consortium goals, aims and implications
Abstract:
The Ireland-Northern Ireland-National Cancer Institute Cancer Consortium was launched in October of 1999, at a conference in Belfast, Northern Ireland, for the development of cancer programs in Ireland and Northern Ireland, where cancer is a significant cause of mortality and morbidity. Cancer services there have undergone major restructuring as a result of several government reports. more...
Geography:
Northern Ireland and the Republic of Ireland
Oncologist,
Vol: 6 Page: 453-8 2001
P. G. Johnston; P. A. Daly
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The aim of this study was to provide representative normal population-based data, or data stratified according to age or gender on the distribution of the common prion protein gene (PRNP) codon 129 polymorphism
Abstract:
OBJECTIVES: The common prion protein gene (PRNP) codon 129 polymorphism modifies the susceptibility to and the phenotype of prion diseases. However, no truly representative normal population-based data, or data stratified according to age or gender are available on the distribution of this polymorphism. MATERIAL AND METHODS: Allelic variation of codon 129 in three Finnish populations more...
International Classification:
Other - prion protein gene
Categories:
prion protein gene
Geography:
International
Acta Neurol Scand,
Vol: 108 Page: 374-8 November 2003
M. H. Nurmi; M. Bishop; L. Strain; F. Brett; C. McGuigan; M. Hutchison; M. Farrell; R. Tilvis; S. Erkkila; O. Simell; R. Knight; M. Haltia
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This study aimed to explore the relationship between the practices of obstetric intervention in individual obstetric units
Abstract:
OBJECTIVE: To investigate the relationship between the practices of obstetric intervention in individual units. STUDY DESIGN: A retrospective analysis of the annual statistical returns to the Royal College of Obstetricians and Gynaecologists of 222 units in the UK for 1997-98. RESULTS: A total of 212 units that delivered more than 1000 babies were analyzed. A positive correlation was more...
International Classification:
Practice/knowledge - Pregnancy, childbirth and the puerperium - practices of obstetric intervention
Categories:
practices of obstetric intervention
Geography:
Republic of Ireland and the United Kingdom
J Matern Fetal Neonatal Med,
Vol: 13 Page: 267-70 April 2003
M. P. O'Connell; E. M. Gurney; S. W. Lindow
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This article discusses exogenous surfactant for respiratory distress syndrome in the newborn
Abstract:
This year is the 20th anniversary of the first successful trial of exogenous surfactant for respiratory distress syndrome in the newborn and it is perhaps a good time to review recent advances in basic science and clinical practice as they relate to surfactant therapy. more...
Geography:
Northern Ireland
Early Hum Dev,
Vol: 61 Page: 67-83 March 2001
A. E. Curley; H. L. Halliday
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The aim of this study was to examine the incidence of Down syndrome and the effects of changing demographics on incidence rates
Abstract:
This is a retrospective survey of all cases of Down syndrome recorded between 1981 and 2000 to mothers resident in Co. Galway. The study compares the incidence of Down syndrome in both decades and examines the effects of changing demographics on incidence rates. The overall prevalence rate was 26.8/10,000 live births for the full period. Although there were 5119 fewer births in the more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Chromosomal abnormalities, not elsewhere classified - Down Syndrome
Categories:
Down Syndrome
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 329-31 January 2007
S. O'Nuallain; O. Flanagan; I. Raffat; G. Avalos; B. Dineen
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This article discusses advances in the understanding of the cells and molecules that mediate immunity, describing the importance of different T helper populations in determining the success of vaccination strategies for neonatal vaccines.
Abstract:
There is an urgent requirement for neonatal vaccines that induce effective and long-lasting immune responses at the mucosal surfaces of the gut and respiratory tract. The delay in their development has been due in part to a lack of understanding of the mucosal and neonatal immune systems. This work reviews recent advances in the understanding of the cells and molecules that mediate more...
Geography:
Republic of Ireland
Curr Med Chem,
Vol: 8 Page: 1057-75 July 2001
B. P. Mahon
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[Read]
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The aim of this study was to examine removals from general practice registration
Abstract:
It has been suggested that there are significant overlaps between removals due to deregistration and removals arising because patients live outside the practice area. If this is true, it would mean that the current estimates of deregistration would need to be revised upwards. All outside-area removals for the calendar years 2001 and 2002 were reviewed and characterised by age, sex and more...
International Classification:
Health service provision
Categories:
general practice registration
Geography:
Northern Ireland
Br J Gen Pract,
Vol: 55 Page: 384-6 May 2005
D. O'Reilly; K. Steele
[Preview]
[Read]
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This article discusses dietary calcium in bone health
Abstract:
Approximately 99% of body Ca is found in bone, where it serves a key structural role as a component of hydroxyapatite. Dietary requirements for Ca are determined by the needs for bone development and maintenance, which vary throughout the life stage, with greater needs during the periods of rapid growth in childhood and adolescence, during pregnancy and lactation, and in later life. more...
Geography:
Republic of Ireland
Proc Nutr Soc,
Vol: 62 Page: 851-8 November 2003
A. Flynn
[Preview]
[Read]
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The aim of this study was to examine Matrix metalloproteinases levels in neonatal bronchoalveolar lavage fluid and its relationship with chronic lung disease
Abstract:
AIM: Matrix metalloproteinases (MMPs) -9 and -2 degrade type-IV collagen, a major constituent of lung basement membrane, and may have a role in the pathogenesis of neonatal chronic lung disease (CLD). We determined factors influencing MMP levels in neonatal bronchoalveolar lavage (BAL) fluid to establish whether an imbalance between MMP and its inhibitor could be implicated in CLD. more...
International Classification:
Diseases of the respiratory system - Chronic lower respiratory diseases - chronic lung disease
Categories:
neonatal bronchoalveolar lavage; chronic lung disease
Geography:
Northern Ireland
Acta Paediatr,
Vol: 93 Page: 791-6 June 2004
D. G. Sweet; A. E. Curley; E. Chesshyre; J. Pizzotti; M. S. Wilbourn; H. L. Halliday; J. A. Warner
[Preview]
[Read]
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This article discusses the role of obstetric events in schizophrenia
Geography:
Republic of Ireland
Schizophr Bull,
Vol: 32 Page: 3-8 January 2006
M. C. Clarke; M. Harley; M. Cannon
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The extracellular matrix scaffold-preliminary results of using urgisis - a biomaterial - in congenital diaphragmatic hernia repair
Abstract:
There is no ideal bio-tensile material for tissue replacement in paediatric surgical conditions. A variety of materials have been described to replace or reinforce tissue deficits in congenital diaphragmatic hernia (CDH). The problems with these materials range from extensive surgery to body wall deformity and hernia recurrence. The ideal graft would be safe, strong, have the potential more...
International Classification:
Procedure - congenital diaphragmatic hernia repair
Categories:
congenital diaphragmatic hernia repair
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 20 Page: 859-62 December 2004
M. J. Smith; T. S. Paran; F. Quinn; M. T. Corbally
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[Read]
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This article discusses the "The Term Breech Trial"
Geography:
Republic of Ireland
J Obstet Gynaecol,
Vol: 26 Page: 491-4 August 2006
M. J. Turner
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[Read]
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The aim of this study was to examine CranioSacral therapy in a physically impaired population in a disability service in southern Ireland
International Classification:
Disabilities - physical
Categories:
CranioSacral therapy; disability service
Geography:
Republic of Ireland
J Altern Complement Med,
Vol: 13 Page: 929-30 November 2007
V. McManus; M. Gliksten
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[Read]
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This study examines the efficacy, long-term survival and adverse event profile of three anti-epiletic agents used as add-on therapy in children with refractory epilepsy over a 10-year period
Abstract:
PURPOSE: Lamotrigine (LTG), vigabatrin (VGB) and gabapentin (GBP) are three anti-epileptic drugs (AEDs) used in the treatment of children with epilepsy for which long-term retention rates are not currently well known. This study examines the efficacy, long-term survival and adverse event profile of these three agents used as add-on therapy in children with refractory epilepsy over a more...
International Classification:
Diseases of the nervous system - Episodic and paroxysmal disorders - epilepsy
Categories:
anti-epiletic agents for refractory epilepsy
Geography:
Republic of Ireland
Seizure,
Vol: 14 Page: 112-6 March 2005
D. G. McDonald; Y. Najam; M. B. Keegan; M. Whooley; D. Madden; J. B. McMenamin
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This study examined a sensitive High Pressure Liquid Chromatography (HPLC) method for the determination of ranitidine in small-volume (0.5 mL) paediatric plasma samples is described
Abstract:
A sensitive HPLC method for the determination of ranitidine in small-volume (0.5 mL) paediatric plasma samples is described. Plasma samples were extracted using a simple, rapid solid phase extraction (SPE) technique developed using disposable copolymer packed SPE cartridges. Chromatographic separation was achieved by reverse-phase HPLC with isocratic elution using a microBondapak C18 more...
International Classification:
Diagnostic tool laboratory - ranitidine hydrochloride
Categories:
ranitidine; paediatric plasma samples
Geography:
Northern Ireland
J Pharm Pharmacol,
Vol: 53 Page: 1265-72 September 2001
L. G. Hare; J. S. Millership; P. S. Collier; J. C. McElnay; D. J. Carson; M. S. Shields
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The aim of this study was to audit the value of perinatal and neonatal autopsy
Abstract:
The postmortem historically has been considered a valuable diagnostic exercise which contributes to medical knowledge. Despite this, there has been a significant reduction in autopsy rates throughout the developed world. This audit was a retrospective study of autopsy reports of stillbirths and neonates [corrected] greater than 500 grams over a five year period from 1995 to 1999. The more...
International Classification:
Deaths - perinatal and neonatal autopsy
Categories:
perinatal and neonatal autopsy
Geography:
Republic of Ireland
Ir Med J,
Vol: 97 Page: 241-4 September 2004
O. G. Killeen; C. Burke; D. Devaney; T. A. Clarke
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This case report discusses Walker-Warburg phenotype and genotype among Irish Travellers
International Classification:
Syndrome
Categories:
Walker-Warburg syndrome
Geography:
Republic of Ireland
Clin Dysmorphol,
Vol: 17 Page: 119-20 April 2008
A. M. Murphy; M. Sheridan; M. B. O'Neill; A. Green
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This study aimed to examined the temperature sensitive of Y42H mutation in medium-chain acyl-CoA dehydrogenase, which is prevalent in babies identified by MS/MS-based (mass spectometry ) newborn screening
Abstract:
Medium-chain acyl-CoA dehydrogenase (MCAD) is a homotetrameric flavoprotein which catalyses the initial step of the beta-oxidation of medium-chain fatty acids. Mutations in MCAD may cause disease in humans. A Y42H mutation is frequently found in babies identified by newborn screening with MS/MS, yet there are no reports of patients presenting clinically with this mutation. As a basis more...
International Classification:
Effectiveness of measurement tool - temperature sensitive of Y42H mutation in medium-chain acyl-CoA dehydrogenase
Geography:
Republic of Ireland
Eur J Biochem,
Vol: 271 Page: 4053-63 October 2004
L. O'Reilly; P. Bross; T. J. Corydon; S. E. Olpin; J. Hansen; J. M. Kenney; S. E. McCandless; D. M. Frazier; V. Winter; N. Gregersen; P. C. Engel; B. S. Andresen
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This article discusses the debate surrounding vitamin K is far from over.
Abstract:
The debate surrounding vitamin K is far from over, says Sara Wickham. more...
Geography:
Republic of Ireland
Practising Midwife,
Vol: 11 Page: 40-40 2008
S. Wickham
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This case report discusses the examination of a 3-dimensional morphology of the myentric plexus of the entire gastrointestinal tract in a newborn with total intestinal aganglionosis
Abstract:
BACKGROUND: Total intestinal aganglionosis (TIA) is a rare form of Hirschsprung's disease (HD). The aim of this study was to examine the 3-dimensional morphology of the myentric plexus of the entire gastrointestinal tract in a newborn with total intestinal aganglionosis. METHODS: Whole-mount preparations were made of the entire gastrointestinal tract using NADPH-diaphorase more...
International Classification:
Diseases of the digestive system - Report
Categories:
intestinal aganglionosis
Geography:
Republic of Ireland
J Pediatr Surg,
Vol: 36 Page: 291-5 February 2001
L. Nemeth; A. Yoneda; M. Kader; D. Devaney; P. Puri
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The aim of this study was to audit the relationship between timing of birth and obstetric and neonatal outcomes, to help plan working patterns under European Working Time Directive legislation
Abstract:
Several studies have reported time of birth is associated with differences in obstetric practice. We investigated the relationship between timing of birth and obstetric and neonatal outcomes, to help plan working patterns under European Working Time Directive (EWTD) legislation. This was a retrospective observational study undertaken in a tertiary-level university teaching hospital. more...
International Classification:
Pregnancy, childbirth and the puerperium - timing of birth and obstetric and neonatal outcomes
Categories:
timing of birth and obstetric and neonatal outcomes
Geography:
Republic of Ireland
Ir Med J,
Vol: 101 Page: 205-7 2008 Jul-Aug
K. O'Donoghue; C. P. Sheridan; K. O'Sullivan; R. A. Greene; J. R. Higgins
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This article discusses NICE guideline on Caesarean Section, their implementation, and discusses guidance on how to achieve recommended practice
Abstract:
The introduction of NICE guidelines in Britain on Caesarean Section provides valuable information on current research findings but little insight into how to implement the guidelines in practice. This is of particular concern when considering the best gestational age to deliver a baby by elective Caesarean Section as this study suggests a major shift in practice would be required to more...
Geography:
Northern Ireland
J Matern Fetal Neonatal Med,
Vol: 17 Page: 137-8 February 2005
F. Alderdice; C. Bailie; J. Dornan; J. Jenkins
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