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The aim of this study was to investigate genotype frequencies for polymorphisms of the TGF-beta1 gene at position -509, codon 10 and 25, and examine circulating levels of TGF-beta1 in patients with reflux nephropathy
Abstract:
PURPOSE: Reflux nephropathy (RN) is recognized as a major cause of end stage renal failure in children and young adults. Transforming growth factor-beta1 (TGF-beta1) is a potent proinflammatory and fibrogenetic cytokine known to have a key role in the regulation of renal tissue fibrosis. We investigate genotype frequencies for polymorphisms of the TGF-beta1 gene at position -509, codon more...
International Classification:
Diseases of the genitourinary system - reflux nephropathy
Categories:
genotype frequencies for polymorphisms of the TGF-beta1 gene; - reflux nephropathy
Geography:
Republic of Ireland
J Urol,
Vol: 174 Page: 1609-11; discussion 1611 October 2005
V. Solari; D. Owen; P. Puri
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The aim of this study was to examine the clinical features, response to therapy and outcome of patients with Mesangioproliferative Glomerulonephritis (MGN) with diffuse IgM deposition
Abstract:
The significance of IgM on immunofluorescence in renal biopsy specimens remains unclear. This retrospective case study was conducted to define the clinical features, response to therapy and outcome of patients with Mesangioproliferative Glomerulonephritis (MGN) with diffuse IgM deposition. Of 1919 native renal biopsies performed over a ten-year period, 139 (7.2%) had light microscopic more...
International Classification:
Other - Mesangioproliferative Glomerulonephritis
Categories:
Mesangioproliferative Glomerulonephritis
Geography:
Republic of Ireland
Ren Fail,
Vol: 22 Page: 445-57 2000
M. A. Little; A. Dorman; D. Gill; J. J. Walshe
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