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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » C » Chemokine CCL2/analysis/ metabolism

Chemokine CCL2/analysis/ metabolism

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1. Epidermal growth factor and monocyte chemotactic peptide-1 expression in reflux nephropathy

The aim of this study was to define the expression of epidermal growth factor and monocyte chemotactic peptide-1 in severe reflux nephropathy in order to further understand the pathogenesis of reflux nephropathy

Abstract:

OBJECTIVES: Reflux nephropathy (RN) is recognised as a major cause of end stage renal failure in children and young adults. The histological findings of RN are tubular atrophy and interstitial monocyte infiltration. Epidermal growth factor (EGF) produced by tubular cells playing a pivotal role in the modulation of tubular cell growth, while monocyte chemotactic peptide-1 (MCP-1) is a more...

International Classification:

Diseases of the genitourinary system - reflux nephropathy

Categories:

epidermal growth factor; monocyte chemotactic peptide-1; - reflux nephropathy

Geography:

Republic of Ireland

Eur Urol, Vol: 44 Page: 144-9 July 2003
B. Chertin; A. Farkas; P. Puri

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