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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » T » Thoracic Neoplasms/genetics

Thoracic Neoplasms/genetics

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1. Coordinate deletion of chromosome 3p and 11q in neuroblastoma detected by comparative genomic hybridization

The aim of this study was to provide insight into some of the less commonly observed abnormalities in neuroblastoma, by performing comparative genomic hybridization analysis on 24 primary and metastatic neuroblastomas

Abstract:

Neuroblastoma, the most common extracranial solid tumor of childhood, is associated with a number of genetic abnormalities that are prognostically significant. The most common abnormalities are associated with aggressive clinical behavior and include deletion of distal chromosome 1p, NMYC amplification, and unbalanced gain of the long arm of chromosome 17. There are also other more...

International Classification:

Neoplasms - Malignant neoplasms - neuroblastoma

Categories:

neuroblastoma

Geography:

Republic of Ireland

Cancer Genet Cytogenet, Vol: 120 Page: 44-9 July 2000
C. J. Breen; A. O'Meara; M. McDermott; M. Mullarkey; R. L. Stallings

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