Irish Child Health Database - Peer Reviewed Papers
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This study examined the incidence of 3'CBFbeta deletion in acute myeloid leukemia
Abstract:
Recent reports have shown that concomitant submicroscopic deletions can occur in association with chromosomal translocations/inversions in several leukemia subtypes. Detectable by fluorescence in situ hybridization (FISH), these losses of sequence include deletion of the 5' region of the ABL gene and the 3' region of BCR in chronic myeloid leukemia (CML) and acute lymphoblastic leukemia more...
International Classification:
Neoplasms - Malignant neoplasms - leukemia
Categories:
acute myeloid leukemia
Geography:
Republic of Ireland
Cancer Genet Cytogenet,
Vol: 162 Page: 122-6 October 2005
J. Kelly; N. J. Foot; E. Conneally; H. Enright; M. Humphreys; K. Saunders; M. J. Neat
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This study examined patients with phaeochromocytoma
Abstract:
Thirty three patients with phaeochromocytomas had surgery in St. Vincent's Hospital between 1950 and 1997. 32 patients had hypertension, 32 had palpitations and 30 had excessive sweating. All patients had at least one of these cardinal symptoms. Diagnostic tests changed over this period. In the early cases the phentolamine test was used, later diagnosis was confirmed by measurement of more...
International Classification:
Neoplasms - Malignant neoplasms - phaeochromocytoma
Categories:
phaeochromocytoma
Geography:
Republic of Ireland
Ir Med J,
Vol: 94 Page: 200-3 2001 Jul-Aug
T. O'Halloran; G. McGreal; E. McDermott; N. O'Higgins
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The aim of this study was to audit the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome
Abstract:
The objective of the investigation was to determine the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome. A prospective audit of patients with complex hydrocephalus undergoing Hakim programmable valve implantation between 1989 and 1994 in the United Kingdom and Ireland, was followed-up for a minimum of 5 more...
International Classification:
Procedure - Hakim valve implants
Categories:
Hakim valve implants
Geography:
Republic of Ireland and the United Kingdom
Br J Neurosurg,
Vol: 14 Page: 535-42 December 2000
A. D. Kay; A. J. Fisher; C. O'Kane; H. K. Richards; J. D. Pickard
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The aim of the study was to examine traditional and otic capsule classification system of temporal bone fractures for clinical relevance
Abstract:
Objectives: To compare the traditional and otic capsule classification system of temporal bone fractures for clinical relevance. Design: A retrospective review of all patients with a radiological diagnosis of a skull-base fracture over a 5-year period. Setting: All patients were seen at Beaumont Hospital, the national tertiary referral centre for Neuro-otology. Participants: Patients more...
International Classification:
Injury, poisoning and certain other consequences of external causes - fractures
Categories:
temporal bone fractures
Geography:
Republic of Ireland
Clinical Otolaryngology,
Vol: 31 Page: 287-291 2006
M. A. Rafferty; R. Mc Conn Walsh; M. A. Walsh
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The aim of this study was to examine the linguistic anthropology which underpins the language dynamics of two Gaeltacht (Irish-speaking) areas
Abstract:
This paper presents an analysis of the linguistic anthropology which underpins the language dynamics of two Gaeltacht (Irish-speaking) areas, Ros Muc in Conamara, Co. Galway and Rath Cairn in Co. Meath. This research highlights what could be considered a socio-linguistic paradox: the community (Rath Cairn) which engages more vigorously in language maintenance endeavors, and exhibits a more...
International Classification:
Anthropology or ethnographic-language
Categories:
linguistic anthropology; language dynamics
Geography:
Republic of Ireland
Coll Antropol,
Vol: 28 Suppl 1 Page: 73-81 2004
C. O. Giollagain
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In this study a retrospective analysis of all consecutive helicopter transfers to the Beaumont neurosurgical unit was performed over a two year period from January 1994 to December 1996.
Abstract:
A retrospective analysis of all consecutive helicopter transfers to the Beaumont neurosurgical unit was performed over a two year period from January 1994 to December 1996. There were 55 transfers, 55% of which were for trauma patients. Sixty two per cent were intubated prior to transfer. The mean length of stay at the referring hospital prior to transfer was 12.25 hours (range 3-98 more...
International Classification:
Economic- Health service provision-transport
Categories:
helicopter transfers
Geography:
Republic of Ireland
Ir Med J,
Vol: 93 Page: 50-1 2000 Mar-Apr
R. Dardis; G. Roberts; J. Phillips
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The aim of this study was to examine the frequency of a false negative result by sequencing studies in patients with hereditary pancreatitis and in healthy controls
Abstract:
BACKGROUND AND AIMS: Hereditary pancreatitis (HP) is a rare form of recurrent acute and chronic pancreatitis. Mutations in the cationic trypsinogen (protease serine 1, PRSS1) gene have been identified as causing HP. The R122H (previously known as R117H) mutation is the commonest and can be detected by a single and rapid polymerase chain reaction/restriction fragment length polymorphism more...
International Classification:
Diseases of the digestive system - Disorders of gallbladder, biliary tract and pancreas - hereditary pancreatitis
Categories:
hereditary pancreatitis;
Geography:
the United Kingdom
Gut,
Vol: 48 Page: 247-50 February 2001
N. Howes; W. Greenhalf; S. Rutherford; M. O'Donnell; R. Mountford; I. Ellis; D. Whitcomb; C. Imrie; B. Drumm; J. P. Neoptolemos
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The aim of this study was to assess the health economics of realtime teledermatology compared with conventional care: an urban versus rural perspective
Abstract:
A randomized controlled trial was carried out to measure the cost-effectiveness of realtime teledermatology compared with conventional outpatient dermatology care for patients from urban and rural areas. One urban and one rural health centre were linked to a regional hospital in Northern Ireland by ISDN at 128 kbit/s. Over two years, 274 patients required a hospital outpatient more...
International Classification:
Evaluation of the effectiveness of teledermatology v. conventional assessment
Categories:
teledermatology v. conventional care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 7 Page: 108-18 2001
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; C. Evans; N. Hicks; P. Jacklin; H. E. Lotery; C. Mathews; J. Paisley; P. Reid; K. Steele; R. Wootton
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The aim of this study was to assess realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial
Abstract:
The clinical effectiveness of realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial. A total of 204 patients took part--102 patients were randomized to the realtime teledermatology consultation, 96 of whose cases were also referred using a store-and-forward technique, and 102 to the more...
International Classification:
Evaluation of the effectiveness of two treatments - in dermatological care
Categories:
dermatological care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 6 Suppl 1 Page: S1-3 2000
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; N. Hicks; H. E. Lotery; C. Mathews; J. Paisley; K. Steele; R. Wootton
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The aim of this study was to examine the number of factors associated with the occurrence of suicide
Abstract:
This study reports on 60 cases of suicide in Londonderry, Northern Ireland from January 2000 to December 2005. The research focused on a number of factors associated with the occurrence of suicide. These included age, gender, employment status, method used and possible predisposing factors. Additionally, the seasonality of occurrence was also investigated. Notably, over the period of more...
International Classification:
External causes of morbidity and mortality - Intentional self-harm - suicide
Categories:
suicide
Geography:
Northern Ireland
J Forensic Leg Med,
Vol: 15 Page: 148-57 April 2008
A. Burns; E. Goodall; T. Moore
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The aim of this study was to examine the incidence, causes, associated factors, and pathological findings in people who died while exercising
Abstract:
BACKGROUND: Sudden death in sport is rare, but when it occurs the effects are devastating. There have not been any reports to date describing the frequency and causes of sudden death in sport in the Republic of Ireland. AIM: To describe the incidence, possible causes, associated factors, and pathological findings in people who died while exercising in the Republic of Ireland in the 10 more...
International Classification:
Deaths - while exercising
Categories:
death while exercising
Geography:
Republic of Ireland
Br J Sports Med,
Vol: 34 Page: 258-61 August 2000
F. Quigley
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This study aimed to review and document the changing patterns in diagnosis, causes and treatment of bacterial infections of the central nervous system in a national neurosurgical unit
Abstract:
OBJECTIVES: To review and document the changing patterns in diagnosis, causes and treatment of bacterial infections of the central nervous system (CNS) in a national neurosurgical unit only in patients from whom a specimen was obtained for culture. METHODS: The case notes, radiological results and laboratory records of all 163 patients in our institution who underwent a neurosurgical more...
International Classification:
Hospital infection - in a neurosurgical unit
Categories:
bacterial infections of the central nervous system
Geography:
Republic of Ireland
Clin Microbiol Infect,
Vol: 9 Page: 803-9 August 2003
M. Roche; H. Humphreys; E. Smyth; J. Phillips; R. Cunney; E. McNamara; D. O'Brien; O. McArdle
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The aim of this study was to examine the absence of Epstein-Barr virus encoded RNA and latent membrane protein (LMP1) in salivary gland neoplasms
Abstract:
A series of 55 (42 benign and 13 malignant) salivary gland tumours were investigated by immunohistochemistry, to detect Epstein-Barr virus (EBV) latent membrane protein (LMP1) and by in situ hybridization for EBV-encoded RNA. Non-neoplastic gland from all the patients with tumours and 15 control glands were also examined. All cases, both neoplastic and non-neoplastic were negative for more...
International Classification:
International committee on Taxonomy of Viruses - Epstein-Barr virus
Categories:
Epstein-Barr virus; -salivary gland neoplasms
Geography:
Republic of Ireland
J Laryngol Otol,
Vol: 113 Page: 906-8 October 1999
A. M. Pollock; M. Toner; M. McMenamin; J. Walker; C. I. Timon
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The aim of this study was to examine rates of acute gastroenteritis in Northern Ireland and the Republic of Ireland
Abstract:
Most people with acute gastroenteritis do not seek medical care and are therefore not captured by routine surveillance. For this reason, population-based studies are needed to measure the burden of illness. A study of acute gastroenteritis in Northern Ireland and the Republic of Ireland surveyed 9,903 people by telephone over the 12-month period from December 2000 to November 2001. The more...
International Classification:
Diseases of the digestive system - acute gastroenteritis
Categories:
acute gastroenteritis
Geography:
Northern Ireland and the Republic of Ireland
Commun Dis Public Health,
Vol: 7 Page: 61-7 March 2004
E. Scallan; M. Fitzgerald; C. Collins; D. Crowley; L. Daly; M. Devine; D. Igoe; T. Quigley; T. Robinson; B. Smyth
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This study described the effect of early administration of analgesia for acute abdominal pain in the accident and emergency setting
Abstract:
BACKGROUND: Recent trials suggest that the early administration of analgesia in patients with acute abdominal pain facilitates examination and does not delay diagnosis. We investigated current practice regarding analgesia for these patients. METHODS: All patients admitted via the accident and emergency department with abdominal pain were included. The main outcome measures evaluated more...
International Classification:
Drugs - analgesia
Categories:
abdominal pain
Geography:
Republic of Ireland
Eur J Emerg Med,
Vol: 11 Page: 309-12 December 2004
J. Shabbir; P. F. Ridgway; K. Lynch; C. E. Law; D. Evoy; J. B. O'Mahony; K. Mealy
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The aim of this study was to describe the age and sex profile of patients having cataract surgery by 2 consulting ophthalmic surgeons over an 18-year period
Abstract:
PURPOSE: To investigate the age and sex profile of patients having cataract surgery by 2 consulting ophthalmic surgeons over an 18-year period. SETTING: Waterford Regional Hospital, Waterford, Republic of Ireland. METHODS: Operating theater logbooks were reviewed, and all patients having cataract surgery between January 1986 and December 2003 in Waterford Regional Hospital were more...
International Classification:
Procedure - cataract surgery
Categories:
cataract surgery
Geography:
Republic of Ireland
J Cataract Refract Surg,
Vol: 31 Page: 2162-6 November 2005
P. O'Reilly; U. Mahmoud; P. Hayes; P. Tormey; S. Beatty
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The aim of this study was to examine the age at death of people with an intellectual disability in Ireland.
Abstract:
This study examined the age at death of people with an intellectual disability in Ireland. Using data from the National Intellectual Disability Database, the average age at death of 1120 people who died between 1996 and 2001 was 45.68 years, with no difference in lifespan between men and women. A more severe level of intellectual disability predicted shorter lifespan. In general, those more...
International Classification:
Mental and behavioural disorders - Mental retardation - intellectual disabilities
Categories:
intellectual disabilities
Geography:
Republic of Ireland
J Intellect Disabil,
Vol: 10 Page: 155-64 June 2006
K. E. Lavin; B. E. McGuire; M. J. Hogan
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The aim of this study was to examine renal replacement therapy in the United Kingdom with regard to prevalence and a range of demographic characteristics
Abstract:
Summary data are provided for the whole United Kingdom. There were 41,776 adult patients alive on renal replacement therapy (RRT) in the UK at the end of 2005, a prevalence for adults of 694 pmp. Addition of 748 children under the age of 18 on RRT gives a total prevalence of 706 pmp. The more detailed analysis includes data on 37,534 patients from 65 of the 70 units which returned more...
International Classification:
Health service provision
Categories:
renal replacement therapy
Geography:
the United Kingdom
Nephrol Dial Transplant,
Vol: 22 Suppl 7 Page: vii30-50 August 2007
K. Farrington; R. Rao; R. Stenkamp; D. Ansell; T. Feest
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The aim of this study was to assess patient satisfaction at two out-of-hours cooperatives in Northern Ireland
Abstract:
BACKGROUND: The reorganized out-of-hours general practitioner (GP) service, resulting in the creation of out-of-hours cooperatives has been widely welcomed by the medical profession. However, GP satisfaction remains only one aspect of this reorganized service and patients' views and levels of satisfaction must have a contribution to make to the organization and delivery of the service. more...
International Classification:
Health service provision
Categories:
patient satisfaction
Geography:
Northern Ireland
J Eval Clin Pract,
Vol: 10 Page: 467-74 August 2004
K. Thompson; K. Parahoo; B. Farrell
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This study investigates a very sensitive non-contact biomotion sensor to measure actimetry and compare its performance to wrist-actimetry
Abstract:
Actimetry is a widely accepted technology for the diagnosis and monitoring of sleep disorders such as insomnia, circadian sleep/wake disturbance, and periodic leg movement. In this study we investigate a very sensitive non-contact biomotion sensor to measure actimetry and compare its performance to wrist-actimetry. A data corpus consisting of twenty subjects (ten normals, ten with sleep more...
International Classification:
Diagnostic tool (biomotion sensor) - wrist-actimetry
Categories:
non-contact biomotion sensor; actimetry (gross motor function); wrist-actimetry
Geography:
International
Conf Proc IEEE Eng Med Biol Soc,
Vol: 2007 Page: 2664-8 2007
N. A. Fox; C. Heneghan; M. Gonzalez; R. B. Shouldice; P. de Chazal
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The aim of the study was to conduct an open-label prospective study assessing the efficacy of activated protein C replacement therapy in patients with severe meningococcal septicemia, purpura fulminans, and multiorgan failure
Abstract:
Activated protein C (APC) is a natural anticoagulant that plays a pivotal role in coagulation homeostasis. Severe inherited or acquired deficiency results in a clinical syndrome called purpura fulminans. In addition, APC also appears to have potent cytokine-modifying properties and is protective in animal models of sepsis. The dual functional properties of APC are particularly relevant more...
International Classification:
Certain infectious and parasitic diseases - Other bacterial diseases - meningococcal disease
Categories:
severe meningococcal septicemia
Geography:
Republic of Ireland
Blood,
Vol: 96 Page: 3719-24 December 2000
B. White; W. Livingstone; C. Murphy; A. Hodgson; M. Rafferty; O. P. Smith
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The aim of this study was to analysis the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk
Abstract:
BACKGROUND: Polymorphisms in the serine protease inhibitor gene serine peptidase inhibitor Kazal type 5 (SPINK5) and the serine protease kallikrein-related peptidase 7 gene (KLK7) appear to confer risk to eczema in some cohorts, but these findings have not been widely replicated. These genes encode proteins thought to be involved in the regulation of posttranslation processing of more...
International Classification:
Diseases of the skin and subcutaneous tissue - Dermatitis and eczema - eczema
Categories:
range of polymorphisms; -eczema risk
Geography:
International
J Allergy Clin Immunol,
Vol: 122 Page: 560-8 e4 September 2008
S. Weidinger; H. Baurecht; S. Wagenpfeil; J. Henderson; N. Novak; A. Sandilands; H. Chen; E. Rodriguez; G. M. O'Regan; R. Watson; H. Liao; Y. Zhao; J. N. Barker; M. Allen; N. Reynolds; S. Meggitt; K. Northstone; G. D. Smith; C. Strobl; C. Stahl; T. Kneib; N. Klopp; T. Bieber; H. Behrendt; C. N. Palmer; H. E. Wichmann; J. Ring; T. Illig; W. H. McLean; A. D. Irvine
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This study examined pitfalls in the acute management of ankle fractures which were referred to a regional orthopaedic unit
Abstract:
OBJECTIVE: The aim of this study was to identify pitfalls in the acute management of ankle fractures which were referred to a regional orthopaedic unit. This unit provides orthopaedic services for the catchment area of the Waterford Emergency Department together with three additional emergency units in the south-eastern region of Ireland. METHODS: This is a retrospective study of all more...
International Classification:
Injury, poisoning and certain other consequences of external causes - fractures
Categories:
ankle fractures
Geography:
Republic of Ireland
Eur J Emerg Med,
Vol: 12 Page: 216-9 October 2005
C. Deasy; D. Murphy; G. C. McMahon; I. P. Kelly
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The aim of this study was to evaluate the use, timing and appropriateness of antimicrobial prophylaxis perioperatively, in otorhinolaryngological/head and neck
procedures.
Abstract:
Prophylactic antimicrobial therapy is defined as the administration of an antimicrobial agent prior to contamination of previously sterile tissues or fluids, in an attempt to reduce the microbial burden of intraoperative contamination. Prophylactic antimicrobial therapy should cover the anticipated floral contamination, with therapeutic levels from incision to closure. There is level I more...
International Classification:
Procedure - otorhinolaryngological
Categories:
otorhinolaryngological
Geography:
Republic of Ireland
Clin Otolaryngol,
Vol: 32 Page: 204-7 June 2007
B. G. Fennessy; M. Harney; M. J. O'Sullivan; C. Timon
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The aim of this study was to measure antimicrobial susceptibility of invasive isolates of Streptococcus pneumoniae in Ireland
Abstract:
Between January 1999 and June 2002, 646 invasive isolates of Streptococcus pneumoniae were collected in Ireland. MICs of penicillin, ciprofloxacin, cefotaxime, moxifloxacin and linezolid were determined by Etest methodology. Eighty-seven (13.5%) isolates showed intermediate resistance to penicillin, while seven (1.1%) showed high-level resistance. Eighty-seven (13.5%) isolates were more...
International Classification:
Bacterium - Streptococcus pneumoniae
Categories:
antimicrobial susceptibility; Streptococcus pneumoniae
Geography:
International
Clin Microbiol Infect,
Vol: 10 Page: 657-9 July 2004
P. Clarke; S. Murchan; E. G. Smyth; H. Humphreys
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The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors
Abstract:
OBJECTIVE: The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors using multiple logistic regression analysis. METHODS: A total of 1328 isolates of Streptococcus pneumoniae, 1894 Haemophilus influenzae and 845 Moraxella more...
International Classification:
Diseases of the respiratory system - lower respiratory pathogens
Categories:
lower respiratory pathogens
Geography:
Republic of Ireland and the United Kingdom
J Antimicrob Chemother,
Vol: 52 Page: 931-43 December 2003
R. Reynolds; J. Shackcloth; D. Felmingham; A. MacGowan
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This study reported use of etanercept and infliximab, novel biological agents, against tumour necrosis factor alpha (TNFalpha)
Abstract:
Etanercept and infliximab are novel biological agents targeted against tumour necrosis factor alpha (TNFalpha), a key cytokine in the pathogenesis of rheumatoid arthritis (RA). We report the results of their use over a two year period in 94 patients with severe inflammatory arthritis. Eighty-eight adults with active inflammatory arthritis (82 with RA), unresponsive to all conventional more...
International Classification:
Other - tumour necrosis factor alpha (TNFalpha)
Categories:
tumour necrosis factor alpha
Geography:
Northern Ireland
Ulster Med J,
Vol: 71 Page: 101-5 November 2002
A. P. Cairns; A. J. Taggart
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This aim of this study was to assess injury-related mortality, disability and disability-adjusted life years (DALYs) in six European countries
Abstract:
OBJECTIVE: To assess injury-related mortality, disability and disability-adjusted life years (DALYs) in six European countries. METHODS: Epidemiological data (hospital discharge registers, emergency department registers, mortality databases) were obtained for Austria, Denmark, Ireland, Netherlands, Norway, and the United Kingdom (England and Wales). For each country, the burden of more...
International Classification:
Injury, poisoning and certain other consequences of external causes - injury
Categories:
injury-related mortality; injury-related disability; disability-adjusted life years
Geography:
International
Bull World Health Organ,
Vol: 85 Page: 27-34 January 2007
S. Polinder; W. J. Meerding; S. Mulder; E. Petridou; E. van Beeck
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The aim of this study was to examine the association between the allele 2 of the interleukin 1 receptor antagonist gene
Abstract:
BACKGROUND AND AIMS: An association between the allele 2 of the interleukin 1 receptor antagonist gene variable number tandem repeats polymorphism in intron 2 and ulcerative colitis was first reported in 1994. Subsequent studies in Caucasian Northern European patients have not confirmed this, although trends towards an association were observed. The lack of statistical significance more...
International Classification:
Diseases of the digestive system - Noninfective enteritis and colitis - ulcerative colitis
Categories:
allele 2 of the interleukin 1 receptor antagonist gene variable; -ulcerative colitis
Geography:
International
Gut,
Vol: 48 Page: 461-7 April 2001
M. J. Carter; F. S. di Giovine; S. Jones; J. Mee; N. J. Camp; A. J. Lobo; G. W. Duff
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The aim of this audit was to determine if a centralised retrieval system for interhospital transport of critically ill patients in Ireland by Mobile Intensive Care Ambulance Service is safe and efficient.
Abstract:
The transfer of critically ill patients between hospitals carries significant risk. The Mobile Intensive Care Ambulance Service (MICAS) in Ireland was established in 1996 to provide a ground transfer service between hospitals for critically ill patients. The aim of this audit was to determine if a centralised retrieval system for interhospital transport of critically ill patients in more...
International Classification:
Factors influencing health status and contact with health services - persons encountering health services for examination and investigation - centralised retrieval system for interhospital transport
Categories:
centralised retrieval system for interhospital transport
Geography:
Republic of Ireland
Ir Med J,
Vol: 99 Page: 76-8 March 2006
D. Rohan; R. Dwyer; J. Costello; D. Phelan
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The aim of this study was to characterise an Irish kindred with apparent autosomal dominant peripheral retinal lesions and peripapillary crescents associated with retinal breaks and uveitis to examine the association with altered homocysteine metabolism
Abstract:
PURPOSE: To characterise an Irish kindred with apparent autosomal dominant peripheral retinal lesions and peripapillary crescents associated with retinal breaks and uveitis and assess whether these findings were associated with altered homocysteine metabolism. METHODS: Family members were followed prospectively and regularly examined. Molecular genetic analysis was performed on family more...
International Classification:
Diseases of the eye and adnexa - Disorders of sclera, cornea, iris and ciliary body - uveitis
Categories:
peripheral retinal lesions; uveitis
Geography:
Republic of Ireland
Graefes Arch Clin Exp Ophthalmol,
Vol: 239 Page: 102-8 February 2001
M. Cahill; P. Gallagher; A. Whitehead; R. Acheson
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This study examined the surgical results of the first one hundred cochlear implant operations at the Belfast Cochlear Implant Centre
Abstract:
We assess the surgical results of the first one hundred cochlear implant operations at the Belfast Cochlear Implant Centre. This paper is in the form of a retrospective case series, taking into account the surgical technique used and any problems encountered. Initially 28 operations were performed using the standard inverted U-shaped incision. After Gibson and Harrison described a more...
International Classification:
Procedure - cochlear implant
Categories:
cochlear implant operations
Geography:
Northern Ireland
Rev Laryngol Otol Rhinol (Bord),
Vol: 121 Page: 9-11 2000
S. M. Hampton; J. G. Toner
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This study analysed the elective MR scans of the lumbosacral spine with findings that Bertolotti's syndrome is a major cause of back pain in young people
Abstract:
Bertolotti's syndrome is characterised by anomalous enlargement of the transverse process(es) of the most caudal lumbar vertebra which may articulate or fuse with the sacrum or ilium and cause isolated L4/5 disc disease. We analysed the elective MR scans of the lumbosacral spine of 769 consecutive patients with low back pain taken between July 2003 and November 2004. Of these 568 showed more...
International Classification:
Syndrome - Bertolotti's
Categories:
Bertolotti's syndrome
Geography:
Republic of Ireland
J Bone Joint Surg Br,
Vol: 88 Page: 1183-6 September 2006
J. F. Quinlan; D. Duke; S. Eustace
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This study evaluated the efficacy of bilateral thoracoscopic sympathectomy in alleviating symptoms and improving quality of life in patients with hyperhidrosis or facial blushing
Abstract:
The aim of this study is to evaluate the efficacy of bilateral thoracoscopic sympathectomy in alleviating symptoms and improving quality of life in patients with hyperhidrosis or facial blushing and to investigate the occurrence, severity and possible underlying factors to compensatory sweating after surgery. One hundred and sixty-three patients in a single institution underwent more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings - General symptoms and signs - hyperhidrosis
Categories:
hyperhidrosis or facial blushing
Geography:
Northern Ireland
Interact Cardiovasc Thorac Surg,
Vol: 7 Page: 67-70 February 2008
R. Jeganathan; S. Jordan; M. Jones; S. Grant; O. Diamond; K. McManus; A. Graham; J. McGuigan
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The aim of this study was to examine the reality, failure and current status of bone anchored hearing aids
Abstract:
Bone Anchored Hearing Aids have both cosmetic and acoustic advantages over most conventional hearing aids and hence is a popular choice today. We report the first Irish group of patients who received a BAHA over a six year period of time and evaluated outcomes of these subjects using subjective assessment. The medical records of all patients who received a BAHA at the Mater and more...
International Classification:
Other - Bone anchored hearing aids
Categories:
Bone anchored hearing aids
Geography:
Republic of Ireland
Irish Medical Journal,
Vol: 97 Page: 312-314 2004
A. L. Kadhim; M. P. Colreavy; C. O'Donovan; A. Blayney
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This case report discusses a selection of cases managed with botulinum toxin and review the current data on use of the toxin to treat salivary gland disorders - Frey's syndrome, excessive salivation, hyperhidrosis, lacrimation and chronic rhinitis.
Abstract:
SUMMARY: The use of botulinum toxin to treat disorders of the salivary glands is increasing in popularity in recent years. Recent reports of the use of botulinum toxin in glandular hypersecretion suggest overall favourable results with minimal side-effects. However, few randomised clinical trials means that data are limited with respect to candidate suitability, treatment dosages, more...
International Classification:
Syndrome
Categories:
botulinum toxin
Geography:
Republic of Ireland
J Plast Reconstr Aesthet Surg,
Vol: 61 Page: 1024-8 September 2008
T. A. Laing; M. E. Laing; S. T. O'Sullivan
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This study aimed to explore General Practitioners in the Mid-West to ascertain their attitudes and practice in relation to breastfeeding
Abstract:
In light of the 1994 National Breastfeeding Policy and the 1999 Mid-Western Health Board (MWHB) Breastfeeding Strategy, a telephone survey of 164 General Practitioners (GPs) in the Mid-West was performed to ascertain their attitudes and practice in relation to breastfeeding. 95% believe breastfeeding promotion is part of their role and almost 40% consider GPs influential in the decision more...
International Classification:
Practice/knowledge - breastfeeding
Categories:
breastfeeding;
Geography:
Republic of Ireland
Ir Med J,
Vol: 97 Page: 268-70 October 2004
B. Finneran; K. Murphy
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This article discusses the role of Calcium and Vitamin D in normal growth and development as well as maintenance of the skeleton
Abstract:
Calcium is required for normal growth and development as well as maintenance of the skeleton. Vitamin D is also essential for intestinal calcium absorption and plays a central role in maintaining calcium homeostasis and skeletal integrity. In addition, both micronutrients have important roles in non-skeletal-related physiological processes. Of concern, significant proportions of some more...
Geography:
Republic of Ireland
Novartis Found Symp,
Vol: 282 Page: 123-38; discussion 138-42, 212-8 2007
K. D. Cashman
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The aim of this study was to examine usual and acute exposure to acrylamidein the Dutch population and young children
Abstract:
In this paper we calculated the usual and acute exposure to acrylamide (AA) in the Dutch population and young children (1-6 years). For this AA levels of different food groups were used as collected by the Institute for Reference Materials and Measurements (IRMM) of the European Commission's Directorate General Joint Research Centre (JRC) from April 2003 up to May 2004. This database more...
International Classification:
Other - acrylamide
Categories:
acrylamide
Geography:
International
Mutat Res,
Vol: 580 Page: 143-55 February 2005
P. E. Boon; A. de Mul; H. van der Voet; G. van Donkersgoed; M. Brette; J. D. van Klaveren
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The aim of this study was to examine the candideamia in an Irish tertiary referral hospital, epidemiology and prognostic factors
Abstract:
There were two parts to this study. Part 1 evaluated the epidemiology of Candida bloodstream isolates within the Southern Health Board (SHB) of Ireland from 1992 to 2003 by retrospective surveillance of all such isolates of patients reported from SHB hospitals to our laboratory database during that period. Part 2 reviewed candidaemia cases occurring in Cork University Hospital (CUH) more...
International Classification:
Fungi - Candideamia
Categories:
Candideamia
Geography:
Republic of Ireland
Mycoses,
Vol: 48 Page: 251-9 July 2005
T. W. Boo; B. O'Reilly; J. O'Leary; B. Cryan
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The aim of this study was to examine the epidemiology of carbon monoxide poisoning in Ireland, using Hospital Inpatient Enquiry (HIPE) data, Mortality data and data from the National Poisons Information Centre
Abstract:
Carbon monoxide (CO) poisoning remains a common preventable cause of morbidity and mortality from poisoning worldwide. Common environmental sources include motor vehicle exhaust, faulty kerosene or gas heaters used in unventilated rooms, and fireplaces with blocked flues. This paper describes the epidemiology of CO poisoning in Ireland, using Hospital Inpatient Enquiry (HIPE) data, more...
International Classification:
Injury, poisoning and certain other consequences of external causes - poisoning
Categories:
carbon monoxide poisoning
Geography:
Republic of Ireland
Ir Med J,
Vol: 96 Page: 83-6 March 2003
D. Crowley; E. Scallan; J. Herbert; A. Staines; B. Herity; J. Tracey
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The aim of this study was to examine the association of particulate pollution (black smoke) and temperature with age-standardized daily mortality rates over 17 years in Dublin,
Abstract:
Air pollution exposure studies in the past decade have focused on acute (days) or long-term (years) effects. We present an analysis of medium-term (weeks to months) exposure effects of particulate pollution and temperature. We assessed the associations of particulate pollution (black smoke) and temperature with age-standardized daily mortality rates over 17 years in Dublin, Ireland, more...
International Classification:
Other - pollution
Categories:
pollution
Geography:
Republic of Ireland
Environ Health Perspect,
Vol: 112 Page: 179-85 February 2004
P. G. Goodman; D. W. Dockery; L. Clancy
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This study aimed to explore primary health professionals' perceptions of, and ability, to recognize child physical abuse in their practice.
Abstract:
The objectives of this cross-sectional survey were to assess primary health professionals' perceptions of and ability to recognize child physical abuse in their practice. A random sample was taken of 979 nurses, doctors, and dentists working in primary care in Northern Ireland. The response rate was 44%, and the results showed that 59% of respondents had seen a suspicious case of child more...
International Classification:
Practice/knowledge - child physical abuse
Categories:
child physical abuse
Geography:
Northern Ireland
Br J Community Nurs,
Vol: 9 Page: 332-8 August 2004
M. Russell; A. Lazenbatt; R. Freeman; W. Marcenes
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This study determined the incidence of, and risk factors for, all stages of chronic kidney disease, as defined in the Kidney Disease Outcomes Quality Initiative Guideline
Abstract:
BACKGROUND: Renal disease is a recognized complication of orthotopic liver transplantation (OLT). We aimed to determine the incidence of all stages of chronic kidney disease (CKD), as defined in the Kidney Disease Outcomes Quality Initiative Guidelines. We also wanted to determine the risk factors for development of CKD and its impact on patient survival. METHODS: All patients who more...
International Classification:
Other - kidney disease
Categories:
chronic kidney disease
Geography:
Republic of Ireland
Nephrol Dial Transplant,
Vol: 21 Page: 2630-6 September 2006
A. O'Riordan; V. Wong; P. A. McCormick; J. E. Hegarty; A. J. Watson
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This study examined a generic adenovirus nested polymerase chain amplification assay designed to be capable of detecting all respiratory adenoviruses.
Abstract:
BACKGROUND: respiratory adenoviruses are common, often resulting in serious sporadic and epidemic infections and impaired immunity can dramatically increase their severity. They are now thought capable of establishing latency. Diagnosis by culture is slow while direct antigen detection by immunofluorescence lacks sensitivity. Molecular diagnosis can be both rapid and sensitive but the more...
International Classification:
Diagnostic tool laboratory - adenovirus
Categories:
Dimercaptosuccinic acid scan (DMSA); Magnetic resonance imaging (MRI)
Geography:
Northern Ireland
J Clin Virol,
Vol: 26 Page: 331-8 April 2003
S. Mitchell; H. J. O'Neill; G. M. Ong; S. Christie; P. Duprex; D. E. Wyatt; C. McCaughey; V. J. Armstrong; S. Feeney; L. Metwally; P. V. Coyle
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This study examined clinical features of newly presenting cases of chronic otitis media
Abstract:
The clinical features of 58 consecutive patients presenting with a new case of chronic otitis media were prospectively collected over a 15-month period. Twenty-three ears had a keratin filled marginal or attic defect (14 with cholesteatoma), 20 had a self-clearing marginal or attic defect, and 21 had a central tympanic membrane perforation (including one cholesteatoma). Twenty patients more...
International Classification:
Diseases of the ear and mastoid process - Diseases of middle ear and mastoid -otitis media
Categories:
otitis media
Geography:
Republic of Ireland
J Laryngol Otol,
Vol: 115 Page: 962-6 December 2001
P. Sheahan; M. Donnelly; R. Kane
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The aim of this study was to audit the number, source, symptoms and diagnosis of neurophysiology referrals in the southern health board region
Abstract:
BACKGROUND: Cork University Hospital (CUH) provides a tertiary service for all neurophysiology referrals in the Southern Health Board region. AIM: To ascertain the number, source, symptoms and diagnosis of neurophysiology referrals at CUH. METHODS: We did a prospective audit of the referral patterns to the neurophysiology department over a 12 -week period. RESULTS: Of 635 referrals, 254 more...
International Classification:
Factors influencing health status and contact with health services - persons encountering health services for examination and investigation - neurophysiology referrals
Categories:
neurophysiology referrals
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 173 Page: 211-4 2004 Oct-Dec
R. Renganathan; S. O'Brien; B. Sweeney; R. Galvin; B. McNamara
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This aim of this study was to measure the extent of the association between Addisons disease and ceoliac disease
Abstract:
BACKGROUND: Coeliac disease has an increased prevalence in a number of autoimmune endocrine conditions. An association between coeliac disease and Addison's disease has been proposed in isolated case reports, but has not been formally studied. AIM: To investigate the extent of this association. DESIGN: Prospective screening of patients with confirmed Addison's disease. METHODS: From more...
International Classification:
Endocrine, nutritional and metabolic diseases or Diseases of the digestive system - Addisons disease and ceoliac disease
Categories:
Addisons disease; ceoliac disease
Geography:
Republic of Ireland
Qjm,
Vol: 95 Page: 79-82 February 2002
C. O'Leary; C. H. Walsh; P. Wieneke; P. O'Regan; B. Buckley; D. J. O'Halloran; J. B. Ferriss; E. M. Quigley; P. Annis; F. Shanahan; C. C. Cronin
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The aim of this study was to examine the impact of consultation charges in deterring patients from seeing the GP
Abstract:
Objective: To estimate the effect of a consultation charge on the health-seeking behaviour of patients. Methods: Cross-sectional survey of patients carried out in Northern Ireland, where services are free at the point of delivery, and the Republic of Ireland, where 70% of the population are charged a consultation fee to see the general practitioner (GP). Results: There were 11 870 more...
International Classification:
Health service provision
Categories:
consultation charges
Geography:
Northern Ireland and the Republic of Ireland
European Journal of General Practice,
Vol: 13 Page: 231-236 2007
D. O'Reilly; T. O'Dowd; K. J. Galway; A. W. Murphy; C. O'Neill; E. Shryane; K. Steele; G. Bury; A. Gilliland; A. Kelly
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The aim of this study was to undertake an economic evaluation of a universal infant hepatitis B vaccination programme, a six-component vaccine, compared with the current strategy of vaccinating high-risk infants with a monovalent hepatitis B vaccine
Abstract:
BACKGROUND: In accordance with World Health Organization recommendations, many European countries have introduced universal hepatitis B vaccination policies. The UK and Ireland are exceptions. In this study, we conducted an economic evaluation of a universal infant hepatitis B vaccination programme, using a six-component vaccine, compared with the current selective strategy of more...
International Classification:
Economic - Vaccinations
Categories:
hepatitis B vaccination
Geography:
Republic of Ireland
Eur J Public Health,
Vol: 18 Page: 275-82 June 2008
L. Tilson; L. Thornton; D. O'Flanagan; H. Johnson; M. Barry
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The aim of this study was to undertake a cost estimation of injury-related hospital admissions in 10 European countries
Abstract:
BACKGROUND: Injuries are a major cause of total health care costs. Cost estimations may help identify injuries and high risk-groups to be considered for potential intervention. METHODS: Hospital discharge registers of 10 European countries were used to estimate injury incidence. Consensus was reached between the participating countries about methodology, definition, classification, cost more...
International Classification:
Economic - Injury, poisoning and certain other consequences of external causes-injury
Categories:
injury-related hospital admissions
Geography:
International
J Trauma,
Vol: 59 Page: 1283-90; discussion 1290-1 December 2005
S. Polinder; W. J. Meerding; M. E. van Baar; H. Toet; S. Mulder; E. F. van Beeck
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