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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » P » Pylorus/pathology

Pylorus/pathology

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1. Increased local synthesis of epidermal growth factors in infantile hypertrophic pyloric stenosis

This study investigated immunohistochemical localization of epidermal growth factors-related peptides and its mRNA expression in pyloric smooth muscle cells to determine involvment with pyloric muscle hypertrophy in infantile hypertrophic pyloric stenosis

Abstract:

Infantile hypertrophic pyloric stenosis (IHPS) is characterized by hypertrophy of the pyloric muscle. The growth of smooth muscle cells is regulated by several growth factors. Epidermal growth factor (EGF) and heparin-binding EGF-like growth factor are potent mitogens for smooth muscle cells. In the present study, we investigated immunohistochemical localization of EGF and EGF-related more...

International Classification:

Congenital malformations, deformations and chromosomal abnormalities - congenital hypertrophic pyloric stenosis

Categories:

epidermal growth factors; -infantile hypertrophic pyloric stenosis

Geography:

Republic of Ireland

Pediatr Res, Vol: 47 Page: 201-7 February 2000
H. Shima; K. Ohshiro; P. Puri

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