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Vesico-Ureteral Reflux/ complications
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The aim of this study was to define the expression of epidermal growth factor and monocyte chemotactic peptide-1 in severe reflux nephropathy in order to further understand the pathogenesis of reflux nephropathy
Abstract:
OBJECTIVES: Reflux nephropathy (RN) is recognised as a major cause of end stage renal failure in children and young adults. The histological findings of RN are tubular atrophy and interstitial monocyte infiltration. Epidermal growth factor (EGF) produced by tubular cells playing a pivotal role in the modulation of tubular cell growth, while monocyte chemotactic peptide-1 (MCP-1) is a more...
International Classification:
Diseases of the genitourinary system - reflux nephropathy
Categories:
epidermal growth factor; monocyte chemotactic peptide-1; - reflux nephropathy
Geography:
Republic of Ireland
Eur Urol,
Vol: 44 Page: 144-9 July 2003
B. Chertin; A. Farkas; P. Puri
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The aim of this study was to examine the distribution of mast cells in kidneys with reflux nephropathy and to determine the relationship between mast cells and the interstitial fibrotic process in reflux nephropathy
Abstract:
End-stage renal disease is characterized by interstitial infiltrate of inflammatory cells in association with tubular atrophy and interstitial fibrosis. Mast cells (MCs) secrete a large number of fibrogenic factors and have been implicated in chronic inflammatory processes with fibrous tissue deposition. The aim of this study was to investigate the distribution of MCs in kidneys with more...
International Classification:
Diseases of the genitourinary system - reflux nephropathy
Categories:
kidney mast cells; - reflux nephropathy
Geography:
Republic of Ireland
Pediatr Nephrol,
Vol: 19 Page: 157-63 February 2004
V. Solari; K. Unemoto; A. Piaseczna Piotrowska; P. Puri
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