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Enteric Nervous System/ pathology
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The aim of this study was to compare the innervation and interstitial cells of Cajal distribution in total colonic and recto-sigmoid Hirschsprung's disease
Abstract:
Total colonic aganglionosis (TCA) is a severe form of ultra long Hirschsprung's disease with an incidence of 2 to 14% among all forms of intestinal aganglionosis. C-kit positive interstitial cells of Cajal (ICCs) are pacemaker cells that play a key role in the motility function of the bowel. The aim of this study was to compare the innervation and ICCs distribution in total colonic and more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease
Categories:
interstitial cells of Cajal; -Hirsprung's Disease
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 19 Page: 349-54 July 2003
V. Solari; A. P. Piotrowska; P. Puri
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This article discusses variant Hirschsprung's disease
Abstract:
Conditions that clinically resemble HD despite the presence of ganglion cells on suction rectal biopsy results, can be diagnosed by providing an adequate biopsy and employing a variety of histological techniques. Intestinal neuronal dysplasia is a distinct clinical entity that can be clearly proven histologically. Patients with IND not only have abnormalities of submucosal and myenteric more...
Geography:
Republic of Ireland
Semin Pediatr Surg,
Vol: 13 Page: 293-9 November 2004
P. Puri; U. Rolle
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