Irish Child Health Database - Peer Reviewed Papers
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Chromosome Banding
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The aim of this study was to examine if gains of chromosomal regions 7q and 11p are important abnormalities in neuroblastoma
Abstract:
Neuroblastoma exhibiting deletion of a segment of the long arm of chromosome 11 represents a genetic subtype of tumor that is distinct from those exhibiting MYCN amplification or 1p deletion. The 11q- genetic subtype is further characterized by gain of 17q and loss of distal 3p material. Gain of 11p material has also been reported in neuroblastoma with 11q loss, but at a considerably more...
International Classification:
Neoplasms - Malignant neoplasms - neuroblastoma
Categories:
neuroblastoma
Geography:
Republic of Ireland
Cancer Genet Cytogenet,
Vol: 140 Page: 133-7 January 2003
R. L. Stallings; J. Howard; A. Dunlop; M. Mullarkey; M. McDermott; F. Breatnach; A. O'Meara
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The aim of this study was to examine comparative genomic hybridization in pediatric acute lymphoblastic leukemia
Abstract:
Comparative genomic hybridization (CGH) was used to clarify the chromosomal status of 15 patients diagnosed with childhood acute lymphoblastic leukemia (ALL). Bone marrow samples from 10 of the 15 patients were selected because no metaphases were obtained for cytogenetic analysis. Three patients with normal trypsin and giemsa banding (GTG) karyotypes were also studied by CGH to more...
International Classification:
Neoplasms - Malignant neoplasms - lymphoblastic leukemia
Categories:
lymphoblastic leukemia
Geography:
Republic of Ireland
Pediatr Hematol Oncol,
Vol: 17 Page: 141-7 March 2000
M. Rice; C. J. Breen; A. O'Meara; F. Breatnach; A. S. O'Marcaigh; R. L. Stallings
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