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Irish Child Health Database - Peer Reviewed Papers

Database Search

Proteinase Inhibitory Proteins, Secretory/ genetics

Your search returns 1 documents

• 1.   Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk

  The aim of this study was to analysis the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk

  

  Abstract:

  BACKGROUND: Polymorphisms in the serine protease inhibitor gene serine peptidase inhibitor Kazal type 5 (SPINK5) and the serine protease kallikrein-related peptidase 7 gene (KLK7) appear to confer risk to eczema in some cohorts, but these findings have not been widely replicated. These genes encode proteins thought to be involved in the regulation of posttranslation processing of more...

  International Classification:

  Diseases of the skin and subcutaneous tissue - Dermatitis and eczema - eczema

  Categories:

  range of polymorphisms; -eczema risk

  Geography:

  International

  J Allergy Clin Immunol, Vol: 122 Page: 560-8 e4 September 2008
  S. Weidinger; H. Baurecht; S. Wagenpfeil; J. Henderson; N. Novak; A. Sandilands; H. Chen; E. Rodriguez; G. M. O'Regan; R. Watson; H. Liao; Y. Zhao; J. N. Barker; M. Allen; N. Reynolds; S. Meggitt; K. Northstone; G. D. Smith; C. Strobl; C. Stahl; T. Kneib; N. Klopp; T. Bieber; H. Behrendt; C. N. Palmer; H. E. Wichmann; J. Ring; T. Illig; W. H. McLean; A. D. Irvine

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