Irish Child Health Database - Peer Reviewed Papers
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This study examined "Dorgan's" percutaneous lateral cross-wiring of supracondylar fractures of the humerus in children
Abstract:
The preferred treatment of displaced supracondylar humeral fractures in children is closed reduction and percutaneous pinning. Cross-wiring techniques are biomechanically superior to parallel lateral wiring techniques. The purpose of this study was to review the authors' experience with a novel cross-wiring technique performed entirely from the lateral side. Twenty children with more...
International Classification:
Injury, poisoning and certain other consequences of external causes - fractures
Categories:
supracondylar fractures of the humerus
Geography:
Republic of Ireland
J Pediatr Orthop,
Vol: 24 Page: 376-9 2004 Jul-Aug
F. J. Shannon; P. Mohan; J. Chacko; L. G. D'Souza
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The aim of this study was to audit the incidence, type of injury, medical consequences and outcome of patients with stab or gunshot wounds presenting to the Mid-Western Regional Hospital, Limerick,
Abstract:
BACKGROUND: According to a recent study in Cardiff, the incidence of stab wounds is 14 per 100,000 population per annum. No such figures are available for Ireland. AIM: To evaluate the incidence, type of injury, medical consequences and outcome of patients with stab or gunshot wounds presenting to the Mid-Western Regional Hospital, Limerick, over a 12 month period. METHOD: A more...
International Classification:
External causes of morbidity and mortality treatment - Accidents - stab or gunshot wounds
Categories:
stab or gunshot wounds
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 173 Page: 102-4 2004 Apr-Jun
J. Shabbir; C. O. McDonnell; J. B. O'Sullivan; K. Cahill; A. Moore; R. Raminlagan; G. Quinn; P. A. Grace
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This study examined the incidence of 3'CBFbeta deletion in acute myeloid leukemia
Abstract:
Recent reports have shown that concomitant submicroscopic deletions can occur in association with chromosomal translocations/inversions in several leukemia subtypes. Detectable by fluorescence in situ hybridization (FISH), these losses of sequence include deletion of the 5' region of the ABL gene and the 3' region of BCR in chronic myeloid leukemia (CML) and acute lymphoblastic leukemia more...
International Classification:
Neoplasms - Malignant neoplasms - leukemia
Categories:
acute myeloid leukemia
Geography:
Republic of Ireland
Cancer Genet Cytogenet,
Vol: 162 Page: 122-6 October 2005
J. Kelly; N. J. Foot; E. Conneally; H. Enright; M. Humphreys; K. Saunders; M. J. Neat
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This study examined patients with phaeochromocytoma
Abstract:
Thirty three patients with phaeochromocytomas had surgery in St. Vincent's Hospital between 1950 and 1997. 32 patients had hypertension, 32 had palpitations and 30 had excessive sweating. All patients had at least one of these cardinal symptoms. Diagnostic tests changed over this period. In the early cases the phentolamine test was used, later diagnosis was confirmed by measurement of more...
International Classification:
Neoplasms - Malignant neoplasms - phaeochromocytoma
Categories:
phaeochromocytoma
Geography:
Republic of Ireland
Ir Med J,
Vol: 94 Page: 200-3 2001 Jul-Aug
T. O'Halloran; G. McGreal; E. McDermott; N. O'Higgins
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The aim of this study was to evaluate long-term outcomes of children who had been inpatients in a child psychiatry unit
Abstract:
The purpose of this study was to evaluate long-term outcomes of children who had been inpatients in a child psychiatry unit. Fifty children, who were consecutive admissions to a Dublin inpatient child psychiatry unit between November 1978 and July 1980, were followed up 16 years later. We obtained some direct information on 33 subjects; of these, 4 subjects had died and 11 subjects more...
International Classification:
Mental and behavioural disorders - psychiatry
Categories:
psychiatry outcomes
Geography:
Republic of Ireland
Eur Child Adolesc Psychiatry,
Vol: 9 Page: 46-53 March 2000
E. Healy; M. Fitzgerald
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Editorial: Discusses a breastfeeding strategy for Northern Ireland
Geography:
Northern Ireland
Ulster Med J,
Vol: 69 Page: 1-2 May 2000
C. M. Campbell
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The aim of this study was to compare the educational and employment experiences of teenage mothers and match peers from a similar social background
Abstract:
Teenage motherhood has been linked with poor health, poor educational attainment, poor employment prospects and socio-economic deprivation. Much of the evidence has come from large surveys and the nature of these inter-relationships remains unclear. A case-control study was designed to compare the educational and employment experiences of teenage mothers with those of an age matched more...
International Classification:
Other - Teenage mothers
Categories:
educational; employment; - teenage mothers
Geography:
Republic of Ireland
Int J Adolesc Med Health,
Vol: 14 Page: 117-23 2002 Apr-Jun
T. Bradley; M. E. Cupples; H. Irvine
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This case report discusses a positive Mantoux test and a chest x-ray consistent with miliary tuberculosis.
Abstract:
A five-year old girl was referred, by the local area medical officer; as she had a positive Mantoux test and a chest x-ray consistent with miliary tuberculosis. She had initially been identified three months previously as a contact of a case of open pulmonary tuberculosis. A CT scan of the brain at the time of presentation showed multiple intracranial tuberculomae. A CT Brain scan three more...
International Classification:
Certain infectious and parasitic diseases - Report
Categories:
miliary tuberculosis
Geography:
Republic of Ireland
Irish Medical Journal,
Vol: 100 Page: 2007
R. J. Drew; A. Tarrant; M. Cafferkey; O. Hensey
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This case report discusses a case treatment - conventional ventilation - of a case of pneumomediastinum in paediatric acute respiratory distress syndrome
Abstract:
An 18-month-old was transferred (intubated and ventilated) to our hospital with staphylococcal tracheitis, which progressed to a necrotizing pneumonitis, complicated by surgical emphysema and pneumomediastinum. Maximum conventional ventilation on a Servo 300 failed. Treatment with high frequency oscillatory ventilation (for 10 days) with a permissive hypercarbia and hypoxaemia strategy more...
International Classification:
Syndrome
Categories:
Acute respiratory distress syndrome
Geography:
Republic of Ireland
Paediatr Anaesth,
Vol: 11 Page: 366-9 May 2001
J. McGinley; T. Corcoran; G. Canny; B. O'Hare
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The aim of this study was to audit the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome
Abstract:
The objective of the investigation was to determine the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome. A prospective audit of patients with complex hydrocephalus undergoing Hakim programmable valve implantation between 1989 and 1994 in the United Kingdom and Ireland, was followed-up for a minimum of 5 more...
International Classification:
Procedure - Hakim valve implants
Categories:
Hakim valve implants
Geography:
Republic of Ireland and the United Kingdom
Br J Neurosurg,
Vol: 14 Page: 535-42 December 2000
A. D. Kay; A. J. Fisher; C. O'Kane; H. K. Richards; J. D. Pickard
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This study aimed to evaluate the effectiveness of a programme of asthma clubs in improving quality of life in primary school children with asthma
Abstract:
AIM: To evaluate the effectiveness of a programme of asthma clubs in improving quality of life in primary school children with asthma. METHODS: A cluster randomised intervention trial was undertaken in 22 primary schools within the urban area of south and east Belfast, Northern Ireland. Schools were randomised in pairs to immediate or delayed groups. The study subjects comprised 173 more...
International Classification:
Diseases of the respiratory system - Chronic lower respiratory diseases - asthma
Categories:
asthma clubs in improving quality of life
Geography:
Northern Ireland
Arch Dis Child,
Vol: 90 Page: 786-91 August 2005
E. E. Patterson; M. P. Brennan; K. M. Linskey; D. C. Webb; M. D. Shields; C. C. Patterson
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The aim of the study was to establish common, symptom-based case definition for gastroenteritis by comparing across four counteries
Abstract:
National studies determining the burden of gastroenteritis have defined gastroenteritis by its clinical picture, using symptoms to classify cases and non-cases. The use of different case definitions has complicated inter-country comparisons. We selected four case definitions from the literature, applied these to population data from Australia, Canada, Ireland, Malta and the United more...
International Classification:
Certain infectious and parasitic diseases - Intestinal infectious diseases - gastroenteritis
Categories:
gastroenteritis
Geography:
United States of America
Epidemiology and Infection,
Vol: 136 Page: 886-894 2008
S. E. Majowicz; G. Hall; E. Scallan; G. K. Adak; C. Gauci; T. F. Jones; S. O'Brien; O. Henao; P. Sockett
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The aim of the study was to examine compare quality of outcomes in patients with unilateral cleft lip and palate between two senior plastic surgeons
Abstract:
OBJECTIVE: The quality of outcomes in patients with unilateral cleft lip and palate (UCLP) was compared between two senior plastic surgeons. One surgeon carried out a one-stage Wardill-Kilner palate repair. The other surgeon employed a vomer flap hard palate repair followed by a von Langenbeck soft palate closure (Oslo protocol). DESIGN: Retrospective analysis. PATIENTS: Thirty-four more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Cleft lip and cleft palate - Cleft lip and/or palate
Categories:
unilateral cleft lip and palate surgery outcomes
Geography:
Northern Ireland
Cleft Palate Craniofac J,
Vol: 41 Page: 42-6 January 2004
C. D. Johnston; A. G. Leonard; D. J. Burden; P. F. McSherry
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The aim of the study was to compare dental caries levels of schoolchildren stratified by social class and fluoridation of drinking water
Abstract:
OBJECTIVES: To compare dental caries levels of schoolchildren stratified in different social classes whose domestic water supply had been fluoridated since birth (Dublin) with those living in an area where fluoridated salt was available (Freiburg). METHODS: A representative, random sample of twelve-year-old children was examined and dental caries was recorded using World Health more...
International Classification:
Dental
Categories:
dental caries
Geography:
International
J Public Health Dent,
Vol: 67 Page: 1-7 2007 Winter
D. Sagheri; J. McLoughlin; J. J. Clarkson
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The aim of this study was to assess visual and structural outcomes after laser photocoagulation and transscleral cryotherapy for threshold retinopathy of prematurity after 10 years
Abstract:
OBJECTIVE: To assess visual and structural outcomes after laser photocoagulation and transscleral cryotherapy for threshold retinopathy of prematurity (ROP) after 10 years. DESIGN: Extended follow-up of a randomized controlled clinical trial. PARTICIPANTS: One hundred eighteen eyes from 66 patients were randomly assigned to receive either cryotherapy or laser photocoagulation for more...
International Classification:
Evaluation of the effectiveness of treatments - retinopathy of prematurity
Categories:
laser photocoagulation and transscleral cryotherapy for retinopathy of prematurity
Geography:
Republic of Ireland
Ophthalmology,
Vol: 109 Page: 928-34; discussion 935 May 2002
E. Y. Ng; B. P. Connolly; J. A. McNamara; C. D. Regillo; J. F. Vander; W. Tasman
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The aim of this study was to examine carotenoids in human and formulae milks
Abstract:
BACKGROUND: Two carotenoids, lutein and zeaxanthin are found in the retinal pigment epithelium of the eye where they are believed to protect it against oxidative and light damage. The amounts of these carotenoids consumed by premature infants are not known. OBJECTIVE: The objective of the investigation was to measure these carotenoids in human and formulae milks. DESIGN: In all, 28 more...
International Classification:
Breastfeeding +/- formulae milk
Categories:
formulae milks
Geography:
Northern Ireland
Eur J Clin Nutr,
Vol: 58 Page: 90-7 January 2004
V. C. Jewell; C. B. Mayes; T. R. Tubman; C. A. Northrop-Clewes; D. I. Thurnham
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The aim of the study was to compare paediatric soccer, gaelic football and rugby injuries presenting to an emergency department in Ireland
Abstract:
OBJECTIVES: Children presenting with sport related injuries (SRIs) as a result of soccer, rugby and gaelic football are frequently seen in an emergency medicine (EM) setting in Ireland. A comparison of the demographics of injuries in these three sports has however not previously been performed. The purpose of this study was to provide up-to-date data on the nature of these SRIs. METHOD: more...
International Classification:
Injury, poisoning and certain other consequences of external causes - injury
Categories:
injuries
Geography:
Republic of Ireland
Injury,
Vol: 38 Page: 104-11 January 2007
K. P. O'Rourke; F. Quinn; S. Mun; M. Browne; J. Sheehan; S. Cusack; M. Molloy
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The aim of the study was to identify the best performing quantitative EEG features for neonatal seizures detection from a test set of 21
Abstract:
OBJECTIVE: This study was undertaken to identify the best performing quantitative EEG features for neonatal seizures detection from a test set of 21. METHODS: Each feature was evaluated on 1-min, artefact-free segments of seizure and non-seizure neonatal EEG recordings. The potential utility of each feature for neonatal seizure detection was determined using receiver operating more...
International Classification:
Neonatal seizures
Categories:
neonatal seizures
Geography:
Republic of Ireland
Clin Neurophysiol,
Vol: 119 Page: 1248-61 June 2008
B. R. Greene; S. Faul; W. P. Marnane; G. Lightbody; I. Korotchikova; G. B. Boylan
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The aim of this study was to test the hypothesis that bone cells respond differently to 0.6 Pa fluid shear stress and 1,000 mu(epsilon) substrate strain stimulation because of qualitative and quantitative differences in cellular deformation
Abstract:
Bone undergoes continuous remodeling in response to mechanical loading. However, the underlying mechanisms by which bone cells respond to their changing mechanical environment, that is, strain in the load-bearing matrix or fluid flow through the canalicular network, are not well understood. It has been established in vitro that bone cells respond differently to substrate strain and more...
International Classification:
Other - bone cells
Categories:
bone cells response
Geography:
Republic of Ireland
Faseb J,
Vol: 19 Page: 482-4 March 2005
J. G. McGarry; J. Klein-Nulend; M. G. Mullender; P. J. Prendergast
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The aim of this study was to examine surgical impression, histological findings and microbiological results at open appendicectomy
Abstract:
There is no accurate predictor of complications following open appendicectomy. Surgical impression, histological findings and peritoneal culture swabs have been used. The value of peritoneal culture swab was assessed in this study. All patients undergoing open appendicectomy between January 2003 and December 2005 were included in the study. During the 24-Month period, 952 patients more...
International Classification:
Diseases of the digestive system - Diseases of appendix - appendicectomy
Categories:
appendicectomy
Geography:
Republic of Ireland
Irish Medical Journal,
Vol: 100 Page: 2007
G. Colleran; H. Heneghan; K. J. Sweeney; M. J. Kerin
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The aim of the study was to examine traditional and otic capsule classification system of temporal bone fractures for clinical relevance
Abstract:
Objectives: To compare the traditional and otic capsule classification system of temporal bone fractures for clinical relevance. Design: A retrospective review of all patients with a radiological diagnosis of a skull-base fracture over a 5-year period. Setting: All patients were seen at Beaumont Hospital, the national tertiary referral centre for Neuro-otology. Participants: Patients more...
International Classification:
Injury, poisoning and certain other consequences of external causes - fractures
Categories:
temporal bone fractures
Geography:
Republic of Ireland
Clinical Otolaryngology,
Vol: 31 Page: 287-291 2006
M. A. Rafferty; R. Mc Conn Walsh; M. A. Walsh
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In this study a retrospective analysis of all consecutive helicopter transfers to the Beaumont neurosurgical unit was performed over a two year period from January 1994 to December 1996.
Abstract:
A retrospective analysis of all consecutive helicopter transfers to the Beaumont neurosurgical unit was performed over a two year period from January 1994 to December 1996. There were 55 transfers, 55% of which were for trauma patients. Sixty two per cent were intubated prior to transfer. The mean length of stay at the referring hospital prior to transfer was 12.25 hours (range 3-98 more...
International Classification:
Economic- Health service provision-transport
Categories:
helicopter transfers
Geography:
Republic of Ireland
Ir Med J,
Vol: 93 Page: 50-1 2000 Mar-Apr
R. Dardis; G. Roberts; J. Phillips
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The article provides a review of the current literature on school bullying in the Northern Ireland school system.
Abstract:
There is great value in exploring the prevalence of school bullying from a cross-national perspective. Smith, Morita, Junger-Tas, Olweus, Catalano, and Slee in 1999 presented a cross-national perspective on the nature, prevalence, and correlates of school bullying that encompassed a wide range of countries. However, Northern Ireland was not included, despite potentially being an more...
Geography:
Northern Ireland
Psychol Rep,
Vol: 93 Page: 279-87 August 2003
C. McGuckin; C. A. Lewis
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This article discusses a difficult diagnosis in a pale child
Geography:
Northern Ireland
Ann Allergy Asthma Immunol,
Vol: 91 Page: 16-9 July 2003
A. J. Thompson; A. J. Reid; D. O'Donoghue; H. J. Steen; M. D. Shields
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The aim of this study was to accelerate the identification of susceptibility genes in diabetic nephropathy using genome-wide fluorescence-based DNA microsatellite
Abstract:
In an effort to accelerate the identification of susceptibility genes in diabetic nephropathy, the first genome-wide fluorescence-based DNA microsatellite (n=6000) association screen was performed, using pools of genomic DNA derived from Irish patients with (cases; n=200) and without (controls; n=200) type 1 diabetic nephropathy. Allele image profiles were generated for 5353 (89.2%) more...
International Classification:
Endocrine, nutritional and metabolic diseases - diabetic nephropathy
Categories:
susceptibility genes; -diabetic nephropathy
Geography:
Northern Ireland
J Am Soc Nephrol,
Vol: 17 Page: 831-6 March 2006
A. J. McKnight; A. P. Maxwell; S. Sawcer; A. Compston; E. Setakis; C. C. Patterson; H. R. Brady; D. A. Savage
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The aim of this study was to examine a genome-wide linkage scan using 4710 single-nucleotide polymorphisms in families with more then one member with Vesicoureteric reflux
Abstract:
BACKGROUND: Vesicoureteric reflux (VUR) is the retrograde flow of urine from the bladder into the ureters. It is the most common urological anomaly in children, and a major cause of end-stage renal failure and hypertension in both children and adults. VUR is seen in approximately 1-2% of Caucasian newborns and is frequently familial. Objective and METHODS: In order to search for genetic more...
International Classification:
Other - genome-wide linkage scan
Categories:
genome-wide linkage scan
Geography:
Republic of Ireland
J Med Genet,
Vol: 44 Page: 710-7 November 2007
H. Kelly; C. M. Molony; J. M. Darlow; M. E. Pirker; A. Yoneda; A. J. Green; P. Puri; D. E. Barton
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The aim of this study was to assess iron status in a sample of clinically well, Caucasian children and explore the complex factors which contribute to iron deficiency during infancy
Abstract:
OBJECTIVES: To assess iron status in a sample of clinically well, Caucasian children and explore the complex factors which contribute to iron deficiency during infancy. DESIGN: Infants recruited at birth and followed longitudinally at 1, 2, 3, 4, 5, 6, 9, 12, 24 and 36 months; feeding practices and socioeconomic data recorded. Iron status assessed using venous blood at 12, 24 and 36 more...
International Classification:
Other - iron status
Categories:
iron status
Geography:
Republic of Ireland
Public Health Nutr,
Vol: 1 Page: 93-100 June 1998
V. E. Freeman; J. Mulder; M. A. van't Hof; H. M. Hoey; M. J. Gibney
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These case reports two individual cases where spontaneous root fracture healing was observed and this healing was apparently not compromised by later orthodontic tooth movement
Abstract:
There is evidence that many dental injuries which result in root fractures may not require active treatment in cases where the coronal fragment is minimally displaced and does not exhibit clinical signs or symptoms. This paper discusses two individual cases where spontaneous root fracture healing was observed and this healing was apparently not compromised by later orthodontic tooth more...
International Classification:
Dental
Categories:
root (tooth) fracture
Geography:
Republic of Ireland
Dent Traumatol,
Vol: 24 Page: 231-4 April 2008
D. Duggan; F. Quinn; M. O'Sullivan
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The aim of this study was to test the hypothesis of the 'Theory of Planned Behaviour' to investigate motivational constructs, prediction of prenatal intentions and the eventual postpartum initiation of breastfeeding
Abstract:
Regressional analysis was used to test the hypothesis of the 'Theory of Planned Behaviour' (Ajzen and Madden, 1986) as a method of investigation of motivational constructs, prediction of prenatal intentions and the eventual postpartum initiation of breastfeeding in 100 women in Northern Ireland.
Application of the theory was based on research by Duckett et al (1998) and led to an more...
International Classification:
Other - Theory of Planned Behaviour
Categories:
Theory of Planned Behaviour
Geography:
Northern Ireland
RCM Midwives Journal,
Vol: 4 Page: 330-333 2001
J. Stockdale
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The aim of this survey was to review published literature and perform a meta-analysis summarizing the evidence in support of an association between children born by Caesarean section and asthma
Abstract:
BACKGROUND: Children born by Caesarean section have modified intestinal bacterial colonization and consequently may have an increased risk of developing asthma under the hygiene hypothesis. The results of previous studies that have investigated the association between Caesarean section and asthma have been conflicting. OBJECTIVE: To review published literature and perform a more...
Categories:
association between children born by Caesarean section and asthma
Geography:
Northern Ireland
Clin Exp Allergy,
Vol: 38 Page: 629-33 April 2008
S. Thavagnanam; J. Fleming; A. Bromley; M. D. Shields; C. R. Cardwell
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The aim of this study was to investigate the relationship between stage of epiphyseal union at the knee joint and chronological age in a modern Irish population
Abstract:
Characteristic changes during epiphyseal union provide a skeletal age, which when compared with age-based standards provides an estimation of chronological age. Currently there are no data on epiphyseal union for the purposes of age estimation specific to an Irish population. This cross-sectional study aims to investigate the relationship between stage of epiphyseal union at the knee more...
International Classification:
Growth and development - epiphyseal union
Categories:
epiphyseal union
Geography:
Republic of Ireland
J Anat,
Vol: 212 Page: 198-209 February 2008
J. E. O'Connor; C. Bogue; L. D. Spence; J. Last
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The aim of this study was to assess early corticosteroid treatment in preterm infants with respiratory illness compared early and late treatment and of dexamethasone and inhaled budesonide
Abstract:
AIM: To compare early (<3 days) with late (>15 days) steroid therapy and dexamethasone with inhaled budesonide in very preterm infants at risk of developing chronic lung disease. METHODS: Five hundred seventy infants from 47 neonatal intensive care units were enrolled. Criteria for enrollment included gestational age <30 weeks, postnatal age <72 hours, and need for mechanical more...
International Classification:
Evaluation of the effectiveness of treatments - preterm infants with respiratory illness
Categories:
preterm infants with respiratory illness
Geography:
International
Pediatrics,
Vol: 107 Page: 232-40 February 2001
H. L. Halliday; C. C. Patterson; C. W. Halahakoon
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[Read]
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This article discusses the national service framework for children
Geography:
Republic of Ireland
Ir Med J,
Vol: 96 Page: 164 June 2003
J. F. Murphy
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[Read]
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The aim of this study was to examine the frequency of a false negative result by sequencing studies in patients with hereditary pancreatitis and in healthy controls
Abstract:
BACKGROUND AND AIMS: Hereditary pancreatitis (HP) is a rare form of recurrent acute and chronic pancreatitis. Mutations in the cationic trypsinogen (protease serine 1, PRSS1) gene have been identified as causing HP. The R122H (previously known as R117H) mutation is the commonest and can be detected by a single and rapid polymerase chain reaction/restriction fragment length polymorphism more...
International Classification:
Diseases of the digestive system - Disorders of gallbladder, biliary tract and pancreas - hereditary pancreatitis
Categories:
hereditary pancreatitis;
Geography:
the United Kingdom
Gut,
Vol: 48 Page: 247-50 February 2001
N. Howes; W. Greenhalf; S. Rutherford; M. O'Donnell; R. Mountford; I. Ellis; D. Whitcomb; C. Imrie; B. Drumm; J. P. Neoptolemos
[Preview]
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The aim of this study was to examine new anthropomorphic parameters as indicators of Cephalopelvic disproportion
Abstract:
Cephalopelvic disproportion (CPD) is a recognised obstetric problem with potential risk to both mother and infant. Identification of those mothers at risk of CPD is difficult and has concentrated in the past on such measurements as maternal shoe size and height. Our objective in this study was to examine new anthropomorphic parameters as indicators of CPD. This was a case controlled more...
International Classification:
Pregnancy, childbirth and the puerperium - cephalopelvic disproportion
Categories:
anthropomorphic parameters; - Cephalopelvic disproportion
Geography:
Republic of Ireland
J Obstet Gynaecol,
Vol: 23 Page: 27-9 January 2003
G. Connolly; C. Naidoo; R. M. Conroy; P. Byrne; P. McKenna
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The aim of this study was to examine a novel primary immunodeficiency consisting of specific natural-killer cell deficiency and susceptibility to viral diseases
Abstract:
We describe four children with a novel primary immunodeficiency consisting of specific natural-killer (NK) cell deficiency and susceptibility to viral diseases. One child developed an Epstein-Barr virus-driven lymphoproliferative disorder; two others developed severe respiratory illnesses of probable viral etiology. The four patients are related and belong to a large inbred kindred of more...
International Classification:
Other - natural-killer (NK) cell deficiency
Categories:
natural-killer (NK) cell deficiency
Geography:
Republic of Ireland
Am J Hum Genet,
Vol: 78 Page: 721-7 April 2006
C. Eidenschenk; J. Dunne; E. Jouanguy; C. Fourlinnie; L. Gineau; D. Bacq; C. McMahon; O. Smith; J. L. Casanova; L. Abel; C. Feighery
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The aim of this study was to describe the clinical features and assess the prevalence of Familial Glucocorticoid Deficiency amongst Irish Travelers in the Republic of Ireland and describe their phenotype.
Abstract:
Context: Familial glucocorticoid deficiency (FGD) is an autosomal recessive disorder characterized by distinct clinical, biochemical, and genetic abnormalities. The prevalence of FGD is unknown, with the likelihood that cases remain undiagnosed. We noted a significant proportion of our FGD cases are Irish Travelers. Irish Travelers are an endogamous nomadic group ethnically and more...
International Classification:
Endocrine, nutritional and metabolic disease - Familial Glucocorticoid Deficiency
Categories:
Familial Glucocorticoid Deficiency; Travellers
Geography:
Republic of Ireland
Journal of Clinical Endocrinology and Metabolism,
Vol: 93 Page: 2896-2899 2008
S. M. P. O'Riordan; S. A. Lynch; P. C. Hindmarsh; L. F. Chan; A. J. L. Clark; C. Costigan
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The aim of this study was to examine if Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma gene could play a role in birth weight and duration of gestation
Abstract:
The links between preterm birth, low birth weight, and adult vascular/metabolic morbidity remain unclear. Genetic susceptibility of babies related to these three conditions might contribute to this long-term association. We tested whether the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma (PPARG) gene could play a role in birth weight and duration of more...
International Classification:
Pregnancy, childbirth and the puerperium - birth weight
Categories:
birth weight; duration of gestation
Geography:
Northern Ireland
Diabetes,
Vol: 56 Page: 494-498 2007
A. Meirhaeghe; C. A. G. Boreham; L. J. Murray; F. Richard; G. Davey Smith; I. S. Young; P. Amouyel
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The aim of this study was to describe intake of vitamin K1 in relation to serum undercarboxylated osteocalcin levels in Irish girls
Abstract:
Low vitamin K1 intakes have been associated with low bone mineral density in women and reduced bone turnover in girls. No European data exist on the relationship between vitamin K1 and serum undercarboxylated osteocalcin (ucOC), an indicator of K1 status in adolescents. The aim of the current study was to assess intakes of vitamin K1 in relation to serum ucOC status in Irish girls. A more...
International Classification:
Vitamin K
Categories:
vitamin K1; serum undercarboxylated osteocalcin levels
Geography:
Republic of Ireland
Int J Vitam Nutr Res,
Vol: 76 Page: 385-90 November 2006
A. Collins; K. D. Cashman; M. Kiely
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The aim of the study was to compare physical and psychological outcomes in children presenting at Accident and Emergency, diagnosed with gastro-enteritis and admitted to hospital with those of a similar age, sex and severity of illness discharged home
Abstract:
OBJECTIVES: To compare physical and psychological outcomes in children presenting at Accident and Emergency Departments (A&E), diagnosed with gastro-enteritis and admitted to hospital with those of a similar age, sex and severity of illness discharged home. The physical and psychological well-being of children in these two groups, in the month after the episode, were compared as was more...
International Classification:
Other - outcomes at A&E
Categories:
physical and psychological outcomes at A&E
Geography:
Northern Ireland
Child: Care, Health & Development,
Vol: 31 Page: 555-562 2005
F. Small; F. Alderdice; C. McCusker; M. Stevenson; M. Stewart
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The aim of this study was to document prospectively the proportion of children with oral lesions at diagnosis of Crohn's disease
Abstract:
BACKGROUND & AIMS: Recent studies suggest that the mouth may be involved frequently in patients with Crohn's disease (CD). The aim of this study was to document prospectively the proportion of children with oral lesions at diagnosis of CD, to describe the type of lesions found, and to examine the ability of gastroenterologists to identify correctly oral Crohn's manifestations. METHODS: more...
International Classification:
Diseases of the digestive system - Noninfective enteritis and colitis - Crohn's disease
Crohn's disease
Categories:
oral lesions; Crohn's disease
Geography:
Republic of Ireland
Clin Gastroenterol Hepatol,
Vol: 3 Page: 886-91 September 2005
S. Harty; P. Fleming; M. Rowland; E. Crushell; M. McDermott; B. Drumm; B. Bourke
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This article discusses a public health approach for preventing child sexual abuse
Geography:
Republic of Ireland
Community Pract,
Vol: 80 Page: 14-5 February 2007
M. Reynolds; P. Blackstock
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The aim of this study was to assess the health economics of realtime teledermatology compared with conventional care: an urban versus rural perspective
Abstract:
A randomized controlled trial was carried out to measure the cost-effectiveness of realtime teledermatology compared with conventional outpatient dermatology care for patients from urban and rural areas. One urban and one rural health centre were linked to a regional hospital in Northern Ireland by ISDN at 128 kbit/s. Over two years, 274 patients required a hospital outpatient more...
International Classification:
Evaluation of the effectiveness of teledermatology v. conventional assessment
Categories:
teledermatology v. conventional care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 7 Page: 108-18 2001
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; C. Evans; N. Hicks; P. Jacklin; H. E. Lotery; C. Mathews; J. Paisley; P. Reid; K. Steele; R. Wootton
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The aim of this study was to assess realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial
Abstract:
The clinical effectiveness of realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial. A total of 204 patients took part--102 patients were randomized to the realtime teledermatology consultation, 96 of whose cases were also referred using a store-and-forward technique, and 102 to the more...
International Classification:
Evaluation of the effectiveness of two treatments - in dermatological care
Categories:
dermatological care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 6 Suppl 1 Page: S1-3 2000
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; N. Hicks; H. E. Lotery; C. Mathews; J. Paisley; K. Steele; R. Wootton
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The aim of this study was to assess "soft cast" or "rigid cast" for distal radius buckle fractures in children
Abstract:
A buckle fracture is a stable fracture where there is a dorsal cortex compression of the distal radius. A total of 117 children with buckle fracture treated at our institution were randomised prospectively into two treatment groups: soft cast or rigid cast. The rigid cast group attended clinic after three weeks for removal of the cast. In the soft cast group, the cast was removed by more...
International Classification:
Evaluation of the effectiveness of treatment - distal radius buckle fractures
Categories:
"soft cast" or "rigid cast" for distal radius buckle fractures
Geography:
Republic of Ireland
Acta Orthop Belg,
Vol: 73 Page: 594-7 October 2007
K. S. Khan; A. Grufferty; O. Gallagher; D. P. Moore; E. Fogarty; F. Dowling
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The aim of this study was to assess the effect of introducing two biophysical ultrasound examinations in a low-risk antenatal population
Abstract:
OBJECTIVE: To evaluate the effect of introducing two biophysical ultrasound examinations in a low-risk antenatal population.Scans were performed at 30-32 weeks' gestation and 36-37 weeks' gestation. METHODS: Scans assessed placental maturity, amniotic fluid volume, and estimated fetal weight. One thousand nine hundred ninety-eight low-risk patients were randomized at 30 weeks' gestation more...
International Classification:
Evaluation of the effectiveness of procedures - two biophysical ultrasound
Categories:
ultrasound examinations in a a low-risk antenatal population
Geography:
Northern Ireland
Obstet Gynecol,
Vol: 101 Page: 626-32 April 2003
D. McKenna; S. Tharmaratnam; S. Mahsud; C. Bailie; A. Harper; J. Dornan
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The aim of this study was to assess the safety and benefits of parenteral glutamine in ill, preterm neonates
Abstract:
OBJECTIVE: The role of "novel substrates" in neonatal nutrition has generated much interest in recent years. Glutamine has been recognized as a "conditionally essential" amino acid in critically ill adults, particularly for gut and immune function; however, its potential role in the neonate remains unclear. The authors examined the safety and benefits of parenteral more...
International Classification:
Evaluation of the effectiveness of treatment -parenteral glutamine
Categories:
parenteral glutamine in ill, preterm neonates
Geography:
Northern Ireland
J Pediatr Gastroenterol Nutr,
Vol: 37 Page: 550-3 November 2003
S. W. Thompson; B. G. McClure; T. R. Tubman
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This case report discusses recurrent splice-site mutation in the human hairless gene underlies congenital atrichia in Irish families
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Report
Categories:
congenital atrichia
Geography:
Republic of Ireland
Br J Dermatol,
Vol: 156 Page: 744-7 April 2007
G. M. O'Regan; J. Zurada; A. Martinez-Mir; A. M. Christiano; A. D. Irvine
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This study examined visual outcome and complications in the treatment of retinoblastoma
Abstract:
The aim of this study was to look at the visual outcome and treatment complications of children diagnosed with Retinoblastoma during the years 1985-2003 inclusive. A retrospective review of all patients records was performed. Patient characteristics, treatment methods and complications were recorded. Twenty eight children presented to Temple street Hospital between 1985-2003. Six of more...
International Classification:
Neoplasms - Malignant neoplasms - retinoblastoma
Categories:
retinoblastoma
Geography:
Republic of Ireland
Ir Med J,
Vol: 98 Page: 17-20 January 2005
M. O'Doherty; B. Lanigan; F. Breathnach; A. O'Meara; B. Gallie; H. Chan; M. O'Keefe
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The aim of this study was to examine demographics of sport and exercise injuries in children presenting to an emergency department
Abstract:
The purpose of this study was to provide up-to-date data on the nature of sport related injury (SRI) presenting to a large emergency department in Ireland. Data were collected retrospectively on all children under 17 years of age with a SRI, presenting to the emergency department of a major teaching hospital, over a 6-month period, and entered into a Microsoft Access database. A total more...
International Classification:
Injury, poisoning and certain other consequences of external causes - injury
Categories:
sport and exercise injuries
Geography:
Republic of Ireland
Eur J Pediatr,
Vol: 164 Page: 421-6 July 2005
K. P. O'Rourke; S. Mun; M. Browne; J. Sheehan; S. Cusack; M. Molloy
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This study examined the presenting features and long-term outcome of all cases of anomalous left coronary artery presenting to our institution over a 15-year period.
Abstract:
BACKGROUND: Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare condition presenting in infancy with acute myocardial ischaemia. AIMS: A retrospective study was undertaken to assess the presenting features and long-term outcome of all cases of ALCAPA presenting to our institution over a 15-year period. METHODS: All the cases were located using the hospital more...
International Classification:
Other - anomalous left coronary artery
Categories:
anomalous left coronary artery
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 177 Page: 127-30 June 2008
M. A. Walsh; D. Duff; P. Oslizlok; M. Redmond; K. P. Walsh; A. E. Wood; D. M. Coleman
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