Irish Child Health Database - Peer Reviewed Papers
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The aim of this study was to evaluate long-term outcomes of children who had been inpatients in a child psychiatry unit
Abstract:
The purpose of this study was to evaluate long-term outcomes of children who had been inpatients in a child psychiatry unit. Fifty children, who were consecutive admissions to a Dublin inpatient child psychiatry unit between November 1978 and July 1980, were followed up 16 years later. We obtained some direct information on 33 subjects; of these, 4 subjects had died and 11 subjects more...
International Classification:
Mental and behavioural disorders - psychiatry
Categories:
psychiatry outcomes
Geography:
Republic of Ireland
Eur Child Adolesc Psychiatry,
Vol: 9 Page: 46-53 March 2000
E. Healy; M. Fitzgerald
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The aim of this study was to examine the prevalence, distribution, and clinical details of paediatric hepatitis C virus infection in the United Kingdom and Ireland.
Abstract:
AIM: To investigate the prevalence, distribution, and clinical details of paediatric hepatitis C virus (HCV) infection in the UK and Ireland. METHODS: Active monthly surveillance questionnaire study coordinated through the British Paediatric Surveillance Unit, to all consultant paediatricians in 1997 and 1998. RESULTS: A total of 182 HCV infected children were reported from 54 centres more...
International Classification:
Certain infectious and parasitic diseases - Viral hepatitis - hepatitis C
Categories:
paediatric hepatitis C virus
Geography:
Republic of Ireland and the United Kingdom
Arch Dis Child,
Vol: 82 Page: 286-91 April 2000
D. M. Gibb; P. E. Neave; P. A. Tookey; M. Ramsay; H. Harris; K. Balogun; D. Goldberg; G. Mieli-Vergani; D. Kelly
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The aim of this study was to examine the relationship between the degree of obesity and glucose metabolism, insulin sensitivity and suspected non-alcoholic steatohepatosis in a pilot study of obese Irish children
Abstract:
BACKGROUND: The metabolic characteristics of obese Irish children are not well defined. We prospectively examined the relationship between the degree of obesity and glucose metabolism, insulin sensitivity and suspected non-alcoholic steatohepatosis (NASH) in a pilot study of obese Irish children. METHODS: We measured height, weight, body mass index (BMI), blood pressure, waist and hip more...
International Classification:
Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - obesity; glucose metabolism; insulin sensitivity; suspected non-alcoholic steatohepatosis
obesity
Categories:
obesity; glucose metabolism; insulin sensitivity; suspected non-alcoholic steatohepatosis
Geography:
Republic of Ireland
Ann Clin Biochem,
Vol: 45 Page: 206-9 March 2008
F. M. Finucane; L. Teong; S. Pittock; M. Fallon; M. Hatunic; C. Costigan; N. Murphy; V. E. Crowley; J. J. Nolan
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The aim of this study was to analysis the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk
Abstract:
BACKGROUND: Polymorphisms in the serine protease inhibitor gene serine peptidase inhibitor Kazal type 5 (SPINK5) and the serine protease kallikrein-related peptidase 7 gene (KLK7) appear to confer risk to eczema in some cohorts, but these findings have not been widely replicated. These genes encode proteins thought to be involved in the regulation of posttranslation processing of more...
International Classification:
Diseases of the skin and subcutaneous tissue - Dermatitis and eczema - eczema
Categories:
range of polymorphisms; -eczema risk
Geography:
International
J Allergy Clin Immunol,
Vol: 122 Page: 560-8 e4 September 2008
S. Weidinger; H. Baurecht; S. Wagenpfeil; J. Henderson; N. Novak; A. Sandilands; H. Chen; E. Rodriguez; G. M. O'Regan; R. Watson; H. Liao; Y. Zhao; J. N. Barker; M. Allen; N. Reynolds; S. Meggitt; K. Northstone; G. D. Smith; C. Strobl; C. Stahl; T. Kneib; N. Klopp; T. Bieber; H. Behrendt; C. N. Palmer; H. E. Wichmann; J. Ring; T. Illig; W. H. McLean; A. D. Irvine
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The aim of this study was to measure apparent low immunisation uptake in Dublin and examine if this is a result of under-performance or under-recording
Abstract:
Through careful follow-up of a cohort, born March to August 1994, we have recorded the highest ever primary immunisation uptake figures for the Dublin area, with completed uptake for Diphtheria, Tetanus and Oral Polio of 92.1%, Haemophilus influenzae type b of 88.7%, Pertussis of 85.7% and Measles/Mumps/Rubella of 78.1%. Eastern Health Board uptake estimates for the same period are more...
International Classification:
Vaccination
Categories:
immunisation uptake
Geography:
Republic of Ireland
Ir Med J,
Vol: 93 Page: 239-40 November 2000
P. M. Harrington; C. Woodman; W. F. Shannon
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The aim of this study was to examine the associations between early life factors and childhood acute lymphoblastic leukaemia
Abstract:
In a historical cohort study of all singleton live births in Northern Ireland from 1971-86 (n=434,933) associations between early life factors and childhood acute lymphoblastic leukaemia were investigated. Multivariable analyses showed a positive association between high paternal age (> or =35 years) and acute lymphoblastic leukaemia (relative risk=1.49; 95% confidence interval more...
International Classification:
Neoplasms-lymphoblastic leukaemia
Categories:
lymphoblastic leukaemia (acute)
Geography:
Northern Ireland
Br J Cancer,
Vol: 86 Page: 356-61 February 2002
L. Murray; P. McCarron; K. Bailie; R. Middleton; G. Davey Smith; S. Dempsey; A. McCarthy; A. Gavin
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The aim of this study was to examine on connexin 26 gene-related deafness mutation analysis along with speech discrimination assessment was undertaken to assess the impact of pediatric cochlear implantees on these disabilities
Abstract:
HYPOTHESIS: Auditory perception and speech discrimination among pediatric cochlear implantees may vary because of underlying deafness etiology, including connexin 26 (GJB2) gene-related deafness. BACKGROUND: Preliminary data suggest pathologic changes due to GJB2 mutations do not affect the spiral ganglion cells, which are stimulated by the cochlear implant. The survival of the spiral more...
International Classification:
Diseases of the ear and mastoid process - Other disorders of ear - deafness
Categories:
deafness; cochlear implant
Geography:
Northern Ireland
Otol Neurotol,
Vol: 25 Page: 930-4 November 2004
A. R. Sinnathuray; J. G. Toner; A. Geddis; J. Clarke-Lyttle; C. C. Patterson; A. E. Hughes
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The aim of this study was to examine the prevalence of birth cleft lip and palate in Northern Ireland for the 20-year period 1981 to 2000, to determine the pattern of prevalence, and to report the proportion of different cleft types and sex distribution
Abstract:
OBJECTIVE: The prevalence of cleft lip and/or palate (CL/P) in Northern Ireland (NI) was last reported for 1980 through 1990. This study was undertaken to update the prevalence of CL/P in NI for the 20-year period 1981 to 2000, to determine the pattern of prevalence, and to report the proportion of different cleft types and sex distribution. DESIGN: Retrospective, population-based more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Cleft lip and cleft palate - Cleft lip and/or palate
Categories:
birth cleft lip; cleft palate
Geography:
Northern Ireland
Cleft Palate Craniofac J,
Vol: 45 Page: 141-7 March 2008
T. A. Gregg; A. G. Leonard; C. Hayden; K. E. Howard; C. F. Coyle
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The aim of this study was to examine the incidence and outcome of birth-associated femoral fractures
Abstract:
Femoral fractures resulting from birth injuries are rare. The authors undertook a study to assess their incidence and outcome. Seven patients from a total of 55,296 live births suffered 8 femoral fractures (incidence 0.13 per 1,000 live births). Twin pregnancies, breech presentations, prematurity, and disuse osteoporosis were associated with the occurrence of a fracture. The typical more...
International Classification:
Injury, poisoning and certain other consequences of external causes - femoral fractures
Categories:
birth-associated femoral fractures
Geography:
Republic of Ireland
J Pediatr Orthop,
Vol: 22 Page: 27-30 2002 Jan-Feb
S. Morris; N. Cassidy; M. Stephens; D. McCormack; F. McManus
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This study examined relationships between aerobic fitness and birthweight in adolescents
Abstract:
The purpose of this study was to examine relationships between aerobic fitness and birthweight in adolescents. A representative cohort of 1015 males and females aged 12 and 15 y was studied, at baseline, with 89% of the 12-y-olds being re-examined 3 y later.The main outcome measures were an index of aerobic fitness, measured in laps completed at voluntary exhaustion by a twenty-metre more...
International Classification:
Longitudinal - Aerobic fitness and birthweight
Categories:
aerobic fitness and birthweight
Geography:
Northern Ireland
Public Health,
Vol: 115 Page: 373-9 November 2001
C. A. Boreham; L. Murray; D. Dedman; G. Davey Smith; J. M. Savage; J. J. Strain
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This study examined the range of cTnT and NTpBNP in preterm infants, correlate NTpBNP and cTnT with echocardiographic markers of cardiac function and assess the influence of antenatal and postnatal factors on these biochemical markers
Abstract:
BACKGROUND: Cardiovascular compromise is increasingly recognized in preterm infants. Currently, echocardiography is the best tool to assess myocardial contractility and guide management. Elevated levels of cardiac troponin T (cTnT) and N-terminal-pro-B type natriuretic peptide (NTpBNP) are associated with poor myocardial contractility and low cardiac output in adults. OBJECTIVE: To more...
International Classification:
Pregnancy, childbirth and the puerperium - cardiac function in preterm infants
Categories:
cardiac function
Geography:
Republic of Ireland
J Perinatol,
Vol: 28 Page: 482-6 July 2008
A. El-Khuffash; P. G. Davis; K. Walsh; E. J. Molloy
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The aim of this study was to examine the spectrum of the mutations identified in the gene responsible for cystic fibrosis in three cohorts of patients of Celtic origin from Brittany and Ireland.
Abstract:
This study aims to compare the spectrum of the mutations identified in the gene responsible for cystic fibrosis in three cohorts of patients of Celtic origin from Brittany and Ireland. It included 389 patients from Brittany, 631 from Dublin and 139 from Cork. The CFTR gene analysis relied on the detection of the most common mutations, followed by a complete gene scanning using DGGE or more...
International Classification:
Endocrine, nutritional and metabolic diseases - Metabolic disorders - cystic fibrosis
Categories:
cystic fibrosis
Geography:
International
Hum Mutat,
Vol: 22 Page: 105 July 2003
V. Scotet; D. E. Barton; J. B. Watson; M. P. Audrezet; T. McDevitt; S. McQuaid; C. Shortt; M. De Braekeleer; C. Ferec; C. Le Marechal
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The aim of this study was to examine the hypothesis that speech intelligibility in children after cochlear implantation may depend on their deafness cause, including connexin 26 (GJB2) gene-related deafness
Abstract:
HYPOTHESIS: Speech intelligibility in children after cochlear implantation may depend on their deafness cause, including connexin 26 (GJB2) gene-related deafness. BACKGROUND: There is significant variability in the degree of intelligibility, or clarity, of children's speech after cochlear implantation. GJB2 gene-related deafness may be a factor, as preliminary data suggest that more...
International Classification:
Diseases of the ear and mastoid process - Other disorders of ear - deafness
Categories:
deafness; cochlear implant
Geography:
Northern Ireland
Otol Neurotol,
Vol: 25 Page: 935-42 November 2004
A. R. Sinnathuray; J. G. Toner; J. Clarke-Lyttle; A. Geddis; C. C. Patterson; A. E. Hughes
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The aim of the study was to compare demographic, social, maternal, and infant related factors associated with partial immunisation and no immunisation in the first year of life in the United Kingdom.
Abstract:
OBJECTIVE: To compare demographic, social, maternal, and infant related factors associated with partial immunisation and no immunisation in the first year of life in the United Kingdom. DESIGN: Prospective cohort study. SETTING: Sample of electoral wards in England, Wales, Scotland, and Northern Ireland, stratified by measures of ethnic composition and social disadvantage. PARTICIPANTS: more...
International Classification:
Vaccination
Categories:
immunisation
Geography:
the United Kingdom
Bmj,
Vol: 332 Page: 1312-3 June 2006
L. Samad; A. R. Tate; C. Dezateux; C. Peckham; N. Butler; H. Bedford
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The aim of this study was to examine United Kingdom country and ethnic variations in infant feeding practices
Abstract:
OBJECTIVE: To examine UK country and ethnic variations in infant feeding practices. DESIGN: Cohort study. SETTING: Infants enrolled in the Millennium Cohort Study, born between September 2000 and January 2002. SUBJECTS: A total of 18 150 natural mothers (11 286 (8207 white) living in England) of singleton infants. OUTCOME MEASURES: Breast-feeding initiation, breast-feeding more...
International Classification:
Other - infant feeding
Categories:
infant feeding practices
Geography:
the United Kingdom
Public Health Nutr,
Vol: 10 Page: 957-64 September 2007
L. J. Griffiths; A. R. Tate; C. Dezateux
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The aim of this study was to examine the reliability of the assumption, - neuropathic bladder behaviour is usually predictable and safe in a child with spina bifida - and whether routine urodynamic studies can be, therefore, safely omitted in this group.
Abstract:
INTRODUCTION: Increased detrusor pressure is a risk factor for renal damage in patients with neuropathic bladder, and probably requires inappropriate contraction of the external urethral sphincter. It seems logical that the absence of sacrally-mediated anal reflexes in a child with spina bifida makes such sphincteric spasm unlikely. One report has suggested that, in such circumstances, more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Congenital malformations of the nervous system - spina bifida
Categories:
neuropathic bladder behaviour; spina bifida
Geography:
Northern Ireland
Eur J Pediatr Surg,
Vol: 11 Suppl 1 Page: S21-3 December 2001
D. F. Marshall; V. E. Boston
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The aim of this study was to audit the effectiveness of wedge resection with phenolization in the surgical treatment of ingrowing toenails
Abstract:
BACKGROUND: Ingrowing toenail is a common condition treated by general surgeons. Our aim was to analyze the effectiveness of wedge resection with phenolization in the surgical treatment of ingrowing toenails. METHODS: We retrospectively audited 100 patients who underwent wedge resection with phenolization for the treatment of ingrowing toenail between January 2000 and June 2004 by a more...
International Classification:
Diseases of the skin and subcutaneous tissue - Disorders of skin appendages - ingrowing toenails
Categories:
surgical treatment of ingrowing toenails
Geography:
Republic of Ireland
J Am Podiatr Med Assoc,
Vol: 98 Page: 118-22 2008 Mar-Apr
F. M. Shaikh; M. Jafri; S. K. Giri; R. Keane
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The aim of this study was to examine the relationship between epidural analgesia and caesarean and instrumental vaginal delivery rates
Abstract:
OBJECTIVE: We sought to examine the relationship between epidural analgesia and cesarean and instrumental vaginal delivery rates. STUDY DESIGN: This is a retrospective analysis of the first 1000 nulliparous pregnancies in women with a cephalic presentation in spontaneous labor at term in each of 3 different years, over which the epidural rate increased from 10% to 57%. RESULTS: Cesarean more...
International Classification:
Pregnancy, childbirth and the puerperium - epidural analgesia and cesarean and instrumental vaginal delivery rates
Categories:
epidural analgesia and cesarean and instrumental vaginal delivery rates
Geography:
Republic of Ireland
Am J Obstet Gynecol,
Vol: 182 Page: 358-63 February 2000
L. Impey; K. MacQuillan; M. Robson
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The aim of this study was to examine national population projections with regard to levels of fertility
Abstract:
One of the key components of national population projections is the assumed level of fertility, which determines the number of future births in the projections. Assumptions are made in terms of the average number of children women will have over their lifetime. For the 2002-based projections this average is assumed to ultimately be 1.75 for England and for Wales, 1.60 for Scotland, and more...
International Classification:
Other - fertility
Categories:
levels of fertility
Geography:
the United Kingdom
Popul Trends,
2003 Winter
S. Smallwood
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The aim of this study was to examine the independence and relative strengths of association between coronary heart disease risk status and both body fatness and cardiorespiratory (C-R) fitness in 12- and 15-yr-old adolescents
Abstract:
PURPOSE: The purpose of this study was to examine the independence and relative strengths of association between coronary heart disease (CHD) risk status and both body fatness and cardiorespiratory (C-R) fitness in 12- and 15-yr-old adolescents. METHODS: The study cohort consisted of 1015 schoolchildren aged 12 and 15 yr (251 12-yr-old boys, 258 12-yr-old girls, 252 15-yr-old boys, and more...
International Classification:
Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - obesity
Categories:
body fatness; cardiorespiratory fitness
Geography:
Northern Ireland
Med Sci Sports Exerc,
Vol: 33 Page: 270-4 February 2001
C. Boreham; J. Twisk; L. Murray; M. Savage; J. J. Strain; G. Cran
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The aim of this study was to evaluate the effectiveness of a school based safety skills program--The Stay Safe Programme--in facilitating the disclosure of sexual abuse among sexually victimized children and adolescents in Dublin
Abstract:
OBJECTIVE: This study aimed to evaluate the effectiveness of a school based safety skills program--The Stay Safe Programme--in facilitating the disclosure of sexual abuse among sexually victimized children and adolescents in Dublin. METHOD: A Cohort of 145 children who had participated in the Stay Safe Programme prior to their referral to a sexual abuse assessment unit were compared more...
International Classification:
Sexual abuse - Stay Safe Programme
Categories:
Stay Safe Programme; -sexual abuse
Geography:
Republic of Ireland
Child Abuse Negl,
Vol: 23 Page: 1327-40 December 1999
D. MacIntyre; A. Carr
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This study assess the predictability of the initial herring classification
Abstract:
The Herring lateral pillar classification has been shown to be a useful predictor of subsequent femoral head deformity in Perthes disease. The initial Herring classification, however, can often be misleading with regard to outcome, as further collapse can occur. The purpose of this study was to assess the predictability of the initial Herring classification. The radiographs of 253 more...
International Classification:
Predictability of herring classification
Categories:
predictability; herring classification
Geography:
Northern Ireland
J Pediatr Orthop,
Vol: 22 Page: 479-82 2002 Jul-Aug
K. Lappin; D. Kealey; A. Cosgrove
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The aim of this study was to describe the decline of CD4 cells or percentage during unplanned treatment interruptions in HIV-infected children
Abstract:
BACKGROUND: There are few data on the decline of CD4 cells or percentage during unplanned treatment interruptions in HIV-infected children. METHODS: Data were analyzed on children undergoing interruptions of three or four drug antiretroviral therapy (HAART) in the United Kingdom and Irish Collaborative HIV Paediatric Study and from Sophia Children's Hospital, Rotterdam. Children were more...
International Classification:
Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV
Categories:
HIV
Geography:
International
Pediatr Infect Dis J,
Vol: 23 Page: 446-50 May 2004
D. M. Gibb; T. Duong; V. A. Leclezio; A. S. Walker; G. Verweel; D. T. Dunn
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This study examined the exclusion criteria for the major severity of disease scoring methods in critical care and to investigate the impact of the exclusion criteria on the case mix, outcomes and length of stay for admissions to intensive care units
Abstract:
OBJECTIVE: To identify the exclusion criteria for the major severity of disease scoring methods in critical care and to investigate the impact of the exclusion criteria on the case mix, outcomes and length of stay for admissions to intensive care units (ICUs) in England, Wales and Northern Ireland. DESIGN: Cohort study-analysis of prospectively collected data. SETTING: 127 adult, more...
International Classification:
Diagnostic tool (inclusion/exclusion criteria) -major severity of disease
Categories:
inclusion/exclusion criteria; critical care
Geography:
the United Kingdom
J Crit Care,
Vol: 19 Page: 67-74 June 2004
H. Wunsch; A. R. Brady; K. Rowan
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The aim of this study was to evaluate the effectiveness of policies and recommendations on folic acid aimed at reducing the occurrence of neural tube defects
Abstract:
OBJECTIVES: To evaluate the effectiveness of policies and recommendations on folic acid aimed at reducing the occurrence of neural tube defects. DESIGN: Retrospective cohort study of births monitored by birth defect registries. SETTING: 13 birth defects registries monitoring rates of neural tube defects from 1988 to 1998 in Norway, Finland, Northern Netherlands, England and Wales, more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - neural tube defects - condiction
Categories:
policies on folic acid
Geography:
International
Bmj,
Vol: 330 Page: 571 March 2005
L. D. Botto; A. Lisi; E. Robert-Gnansia; J. D. Erickson; S. E. Vollset; P. Mastroiacovo; B. Botting; G. Cocchi; C. de Vigan; H. de Walle; M. Feijoo; L. M. Irgens; B. McDonnell; P. Merlob; A. Ritvanen; G. Scarano; C. Siffel; J. Metneki; C. Stoll; R. Smithells; J. Goujard
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The aim of this study was to examine infant weight gain over a ten year period
Abstract:
Weight gain between birth and 9 months of 12 903 term Millennium Cohort Study infants was investigated in order to determine differences according to sex, ethnicity and country of birth. The standardised weights and weight gains were also compared with a cohort of mainly white infants born 10 years earlier to determine whether weight gain has changed over the last decade. There were more...
International Classification:
Other - Anthropometry-infant weight
Categories:
infant weight gain
Geography:
the United Kingdom
Int J Obes (Lond),
Vol: 30 Page: 1094-6 July 2006
A. R. Tate; C. Dezateux; T. J. Cole
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The aim of this study was to examine the association of IL-8 gene polymorphism with familial vesico-ureteral reflux in a cohort of 219 siblings from 109 families affected with vesico-ureteral reflux
Abstract:
Vesico-ureteral reflux (VUR) is the most common inherited disorder of the lower urinary tract. Children with VUR are at risk for ongoing renal damage with subsequent infections. IL8 is an important inflammatory mediator which can be produced by epithelial cells of the renal tract in response to a variety of inflammatory stimuli. High serum concentrations of IL-8 have been reported in more...
International Classification:
Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux
Categories:
IL-8 gene polymorphism; vesico-ureteral reflux
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 23 Page: 441-5 May 2007
S. Kuroda; P. Puri
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This study aimed to augment parent interview data - in the Millenniun Cohort Study - with information from birth registrations and hospital records.
Abstract:
The Millennium Cohort Study of 18,818 UK babies born in 2000-02 interviewed parents when the baby was 9 months old. Time constraints on the interview limited the amount of health-related questions that could be included. The aim of this study was to augment interview data with information from birth registrations and hospital records. It also provided an opportunity to assess the more...
International Classification:
Effectiveness of measurement tool - parent interview data - in the Millenniun Cohort Study
Categories:
augment parent interview data - in the Millenniun Cohort Study
Geography:
the United Kingdom
Paediatr Perinat Epidemiol,
Vol: 22 Page: 99-109 January 2008
C. Hockley; M. A. Quigley; G. Hughes; L. Calderwood; H. Joshi; L. L. Davidson
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This study examines mothers satisfaction with the process of immunisation and its possible contribution to suboptimal immunisation uptake
Abstract:
OBJECTIVE: To examine mothers' satisfaction with the process of immunisation and its possible contribution to suboptimal immunisation uptake. DESIGN: In depth interviews with mothers. SETTING: Two Community Care Areas, Dublin city, Ireland. PARTICIPANTS: In depth interviews of 23 mothers of children 1-2 years old, recruited purposively from a birth cohort born in 1994. MAIN RESULTS: more...
International Classification:
Vaccination
Categories:
immunisation satisfaction
Geography:
Republic of Ireland
J Epidemiol Community Health,
Vol: 54 Page: 394-400 May 2000
P. M. Harrington; C. Woodman; W. F. Shannon
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The aim of this study was to describe the risk of malignancy and mortality in patients with a positive endomysial or anti-gliadin antibody test in Northern Ireland
Abstract:
AIM: To determine the risk of malignancy and mortality in patients with a positive endomysial or anti-gliadin antibody test in Northern Ireland. METHODS: A population-based retrospective cohort study design was used. Laboratory test results used in the diagnosis of coeliac disease were obtained from the Regional Immunology Laboratory, cancer statistics from the Northern Ireland Cancer more...
International Classification:
Other - malignancy; mortality; positive endomysial; anti-gliadin antibody test
Categories:
malignancy; mortality; positive endomysial; anti-gliadin antibody tes
Geography:
Northern Ireland
World J Gastroenterol,
Vol: 13 Page: 146-51 January 2007
L. A. Anderson; S. A. McMillan; R. G. Watson; P. Monaghan; A. T. Gavin; C. Fox; L. J. Murray
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The aim of this study was to examine the Millennium Cohort Study to determine whether a mother's employment status and employment characteristics are related to breast-feeding initiation.
Abstract:
Maternal employment rates have increased rapidly in recent years and little is known about how this influences whether women start breast feeding. We examined data from the Millennium Cohort Study to determine whether a mother's employment status (full-time, part-time, self-employed, on leave, not employed/student) and employment characteristics are related to breast-feeding initiation. more...
International Classification:
Pregnancy, childbirth and the puerperium - breast-feeding
Categories:
breast-feeding
Geography:
Republic of Ireland
Paediatr Perinat Epidemiol,
Vol: 21 Page: 242-7 May 2007
S. S. Hawkins; L. J. Griffiths; C. Dezateux; C. Law
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The aim of this study was to assess the incidence of meconium that can only have been passed intrapartum and to determine its neonatal associations and whether its absence is a useful sign
Abstract:
OBJECTIVE: Clear amniotic fluid is frequently considered a reassuring sign during labor. Our aim was to examine the incidence of meconium that can only have been passed intrapartum and to determine its neonatal associations and whether its absence is a useful sign. METHODS: This was a prospective cohort study of 8394 "low risk" laboring women at term with clear amniotic fluid more...
International Classification:
Evaluation of the impact of intrapartum meconium monitoring on managing pregnant women
Categories:
intrapartum meconium
Geography:
Republic of Ireland and the United Kingdom
Obstet Gynecol,
Vol: 102 Page: 89-93 July 2003
C. Greenwood; S. Lalchandani; K. MacQuillan; O. Sheil; J. Murphy; L. Impey
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The aim of this study was to examine temporal changes in the morbidity and mortality persons with perinatally acquired HIV infection, many of whom are now adolescents.
Abstract:
BACKGROUND: Recent evidence suggests that decreases in morbidity and mortality in cohorts of adults infected with human immunodeficiency virus (HIV) are showing signs of reversal. We describe changes over time in these characteristics and in the response to treatment among children in the United Kingdom and Ireland with perinatally acquired HIV infection, many of whom are now more...
International Classification:
Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV
Categories:
perinatally acquired HIV infection
Geography:
Republic of Ireland and the United Kingdom
Clin Infect Dis,
Vol: 45 Page: 918-24 October 2007
A. Judd; K. Doerholt; P. A. Tookey; M. Sharland; A. Riordan; E. Menson; V. Novelli; E. G. Lyall; J. Masters; G. Tudor-Williams; T. Duong; D. M. Gibb
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The aim of this study was to examine the effect of risk factors, including mode of delivery, on the vertical transmission rate of hepatitis C
Abstract:
BACKGROUND: Little information is available about the timing of mother-to-child transmission of hepatitis C virus (HCV), and no interventions to decrease transmission rates have been identified. We examined the effect of risk factors, including mode of delivery, on the vertical transmission rate. METHODS: Data from HCV-infected women and their infants from three hospitals in Ireland and more...
International Classification:
Certain infectious and parasitic diseases - Viral hepatitis - hepatitis C
Categories:
hepatitis C
Geography:
Republic of Ireland and the United Kingdom
Lancet,
Vol: 356 Page: 904-7 September 2000
D. M. Gibb; R. L. Goodall; D. T. Dunn; M. Healy; P. Neave; M. Cafferkey; K. Butler
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The aim of this study was to describe outbreak of mumps in the Mid-Ulster area of Northern Ireland between 1st November 1999 and 31st August 2000
Abstract:
An outbreak of mumps occurred in the Mid-Ulster area of Northern Ireland between 1st November 1999 and 31st August 2000, with 729 cases notified. Salivary test results were obtained for 430 (59%) reported cases, of which 332 (77%) were positive for mumps IgM antibody. Three hundred and sixteen (95.2%) of these confirmed cases were in the age range 9 to 19. One hundred and eighty-four more...
International Classification:
Certain infectious and parastic diseases - Other viral diseases - mumps
Categories:
mumps
Geography:
Northern Ireland
Commun Dis Public Health,
Vol: 4 Page: 311-5 December 2001
E. A. Reaney; V. K. Tohani; M. J. Devine; R. D. Smithson; B. Smyth
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The aim of this study was to determine the incidence and persistence of neonatal brachial plexus paralysis and evaluated whether its occurrence could be predicted by maternal characteristics or partographic analysis in a large cohort of recent cases
Abstract:
OBJECTIVE: Brachial plexus paralysis is a serious form of neonatal morbidity. We determined its incidence and persistence of disability and evaluated whether its occurrence could be predicted by maternal characteristics or partographic analysis in a large cohort of recent cases. STUDY DESIGN: During the years 1994 through 1998, all infants with neonatal evidence of obstetric brachial more...
International Classification:
Certain conditions originating in the perinatal period - brachial plexus paralysis
Categories:
maternal characteristics or partographic analysis; -neonatal brachial plexus paralysis
Geography:
Republic of Ireland
Am J Obstet Gynecol,
Vol: 187 Page: 1209-12 November 2002
V. Donnelly; A. Foran; J. Murphy; P. McParland; D. Keane; C. O'Herlihy
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The aim of this study was to examine neurologic and developmental disability in children who were born at 25 or fewer completed weeks of gestation in the United Kingdom and Ireland
Abstract:
BACKGROUND AND METHODS: Small studies show that many children born as extremely preterm infants have neurologic and developmental disabilities. We evaluated all children who were born at 25 or fewer completed weeks of gestation in the United Kingdom and Ireland from March through December 1995 at the time when they reached a median age of 30 months. Each child underwent a formal more...
International Classification:
Premature - children
Categories:
Neurologic and developmental disability; preterm births
Geography:
Republic of Ireland and the United Kingdom
N Engl J Med,
Vol: 343 Page: 378-84 August 2000
N. S. Wood; N. Marlow; K. Costeloe; A. T. Gibson; A. R. Wilkinson
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The aim of this study was to examine four single nucleotide polymorphisms two of which (rs1843809, rs1386493) were reported to associate with attention-deficit hyperactivity disorder
Abstract:
Tryptophan Hydroxylase 2 (TPH2) is the rate-limiting enzyme in the biosynthesis of serotonin which is exclusively expressed in the brain. Recent molecular studies reported significant association between markers mapped to TPH2 and psychiatric conditions including ADHD. We have examined four single nucleotide polymorphisms (SNPs) two of which (rs1843809, rs1386493) were reported to more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
Republic of Ireland
Neurosci Lett,
Vol: 412 Page: 105-7 January 2007
K. Sheehan; Z. Hawi; M. Gill; L. Kent
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This study examined the clinical characteristics, aetiology, neuro-physiological characteristics, imaging findings and other investigations in a cohort of patients with non-traumatic brachial plexopathy
Abstract:
OBJECTIVE: To establish the clinical characteristics, aetiology, neuro-physiological characteristics, imaging findings and other investigations in a cohort of patients with non-traumatic brachial plexopathy (BP). METHODS: A 3-year retrospective study of patients with non-traumatic BP identified by electromyography (EMG) and nerve conduction studies (NCS). Clinical information was more...
International Classification:
Diseases of the nervous system - Nerve, nerve root and plexus disorders - non-traumatic brachial plexopathy
Categories:
non-traumatic brachial plexopathy
Geography:
Republic of Ireland
Clin Neurol Neurosurg,
Vol: 109 Page: 661-6 October 2007
G. M. Mullins; S. S. O'Sullivan; A. Neligan; S. Daly; R. J. Galvin; B. J. Sweeney; B. McNamara
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The aim of the study was to examine the effects of maternal body mass index on the mode of delivery for primigravid and multigravid women.
Abstract:
Our objective was to study the effects of maternal body mass index (BMI) on the mode of delivery for primigravid and multigravid women. A retrospective cohort study was conducted at the University College Hospital Galway, Ireland, of 5162 women delivered from 2001 to 2003. BMI at the first antenatal appointment was calculated. Comparisons were made between each of the five BMI more...
International Classification:
Pregnancy, childbirth and the puerperium
Categories:
maternal body mass index on mode of delivery
Geography:
Republic of Ireland
Am J Perinatol,
Vol: 25 Page: 163-7 March 2008
C. M. Lynch; D. J. Sexton; M. Hession; J. J. Morrison
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The aim of this study was to examine the feasibility of using established methods and routinely generated data from the statutory primary school health-screening programme to estimate prevalence rates for overweight and obesity in children
Abstract:
BACKGROUND: This retrospective cohort study investigates the feasibility of using established methods and routinely generated data from the statutory primary school health-screening programme to estimate prevalence rates for childhood overweight and obesity in children from a rural area in the Republic of Ireland (ROI). METHOD: Paper-based records in the primary school health service more...
International Classification:
Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - overweight and obese
Categories:
overweight; obesity
Geography:
Republic of Ireland
Child Care Health Dev,
Vol: 31 Page: 499-506 September 2005
C. McMaster; L. Cullen; N. Raymond
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The aim of this study was to examine perinatal risk factors for childhood Type 1 diabetes
Abstract:
AIMS: To investigate perinatal risk factors for childhood Type 1 diabetes in a UK population cohort. METHODS: Perinatal data have been routinely recorded in Northern Ireland for all births in the period 1971-86 (n = 447 663). Diabetes status at the age of 15 years was ascertained in this cohort by identifying 991 children from 1079 registered with Type 1 diabetes diagnosed from 1971 to more...
International Classification:
Endocrine, nutritional and metabolic diseases - Diabetes mellitus - type 1 diabetes mellitus
Categories:
type 1 diabetes
Geography:
the United Kingdom
Diabet Med,
Vol: 22 Page: 200-6 February 2005
C. R. Cardwell; D. J. Carson; C. C. Patterson
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The aim of this study was to investigate the leisure and recreational activities of a cohort of 34 students attending a full-time special school as reported by the students and their parents
Abstract:
The aim of this study was to investigate the leisure and recreational activities of a cohort of 34 students attending a full-time special school as reported by the students and their parents. Leisure activities which were mostly solitary and passive in nature were identified as those being most commonly engaged in. Barriers to leisure were also identified, with 'access to' and 'location more...
International Classification:
Physical activity
Categories:
leisure and recreational activities of special needs students
Geography:
Republic of Ireland
J Intellect Disabil,
Vol: 9 Page: 25-42 March 2005
J. Buttimer; E. Tierney
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The aim of this study was to describe patterns of milk and food intake in infants from birth to age 36 months
Abstract:
BACKGROUND: Little detailed information is available on feeding practices of infants in Europe. The Euro-Growth Study is a longitudinal, observational, multicenter study of milk feeding, the introduction of complementary solid foods, and vitamin and mineral supplementation. Current practice is compared with international feeding recommendations. METHOD: Healthy term infants (n = 2,245) more...
International Classification:
Diet and lifestyle
Categories:
diet
Geography:
International
J Pediatr Gastroenterol Nutr,
Vol: 31 Suppl 1 Page: S76-85 2000
V. Freeman; M. van't Hof; F. Haschke
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The aim of this study was to examine perinatal factors and preterm delivery in an Irish obstetric population
Abstract:
The aim of this study was to ascertain the incidence of preterm delivery, the associated etiological factors and consequent perinatal mortality in an Irish obstetrical population. All deliveries between 24 + 0 and 36 + 6 weeks of gestation that occurred during the five year period 1992-1996 were included in the study. The overall group of preterm deliveries was also analyzed separately more...
International Classification:
Pregnancy, childbirth and the puerperium - perinatal factors and preterm delivery
Categories:
perinatal factors and preterm delivery
Geography:
Republic of Ireland
J Perinat Med,
Vol: 28 Page: 49-53 2000
C. Burke; J. J. Morrison
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The aim of this study was to examine the prevalence and correlates of overweight and obesity among children and adolescents in the Republic of Ireland (RoI) and Northern Ireland (NI).
Abstract:
BACKGROUND: Childhood obesity is emerging as a major public health problem in developed and developing countries worldwide. The aim of this survey was to establish baseline data on the prevalence and correlates of overweight and obesity among children and adolescents in the Republic of Ireland (RoI) and Northern Ireland (NI). METHODS: The heights and weights of 19,617 school-going more...
International Classification:
Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - obesity
Categories:
overweight; obesity
Geography:
Northern Ireland and the Republic of Ireland
BMC Public Health,
Vol: 7 Page: 187 2007
H. Whelton; J. Harrington; E. Crowley; V. Kelleher; M. Cronin; I. J. Perry
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The aim of this study was to estimate the societal costs of extreme premature birth during the 6th year after birth
Abstract:
BACKGROUND: Previous assessments of the economic impact of preterm birth focussed on short term health service costs across the broad spectrum of prematurity. OBJECTIVE: To estimate the societal costs of extreme preterm birth during the sixth year after birth. METHODS: Unit costs were applied to estimates of health, social and broader resource use made by 241 children born at 20 through more...
International Classification:
Economic - Extreme premature birth
Categories:
premature birth
Geography:
Republic of Ireland and the United Kingdom
Early Hum Dev,
Vol: 82 Page: 77-84 February 2006
S. Petrou; J. Henderson; M. Bracewell; C. Hockley; D. Wolke; N. Marlow
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We evaluated the incidence of readmission with respiratory syncytial virus infection among the graduates of a regional Neonatal Intensive Care Unit, and characterized those who were rehospitalized
Abstract:
We evaluated the incidence of readmission with respiratory syncytial virus (RSV) infection among the graduates of a regional Neonatal Intensive Care Unit (NICU), and characterized those who were rehospitalized. These data were used as a predictive tool to estimate the number of babies likely to suffer readmission with RSV for the year 2000 cohort. Using the published efficacies of more...
International Classification:
Economic - Health service provision-readmissions
Categories:
respiratory syncytial virus
Geography:
Northern Ireland
Pediatr Pulmonol,
Vol: 34 Page: 262-6 October 2002
J. McCormick; R. Tubman
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The aim of this study was to examine the recurrence rate of macrosomia in non-diabetic pregnancy and to see if the history of multiple prior macrosomic infants confers additional risk
Abstract:
Fetal macrosomia (birth weight >/=4,500 g) is known to increase a number of adverse maternal and perinatal outcomes. Although there is a clear association between maternal diabetes mellitus and fetal macrosomia, the majority of macrosomic infants are born to non-diabetic mothers. We wished to determine the recurrence rate of macrosomia in non-diabetic pregnancy and to see if a history more...
International Classification:
Pregnancy, childbirth and the puerperium
Categories:
macrosomia in non-diabetic pregnancy; macrosomic infants
Geography:
Republic of Ireland
J Obstet Gynaecol,
Vol: 27 Page: 374-8 May 2007
C. A. Walsh; R. T. Mahony; M. E. Foley; L. Daly; C. O'Herlihy
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This study aimed to evaluate the relationship between perceptual assessment and acoustic measurements of nasality using controlled speech stimuli.
Abstract:
BACKGROUND: Nasometry has supplemented perceptual assessments of nasality, using speech stimuli, which are devoid of nasal consonants. However, such speech stimuli are not representative of conversational speech. A weak relationship has been found in previous studies between perceptual ratings of hypernasality and nasalance scores for passages containing nasal consonants. AIMS: This more...
International Classification:
Effectiveness of measurement tool - perceptual assessment, controlled speech stimuli
Categories:
perceptual assessment; acoustic measurements of nasality; controlled speech stimuli.
Geography:
Republic of Ireland
Int J Lang Commun Disord,
Vol: 43 Page: 265-82 2008 May-Jun
T. Sweeney; D. Sell
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The aim of this study was to evaluate the effect of age, CD4 percentage (CD4%) and plasma HIV-1 RNA on response to highly active antiretroviral therapy in previously untreated children
Abstract:
OBJECTIVE: To evaluate the effect of age, CD4 percentage (CD4%) and plasma HIV-1 RNA on response to highly active antiretroviral therapy (HAART) in previously untreated children. DESIGN: Cohort study. METHODS: We examined the association between age at HAART initiation, and CD4 and HIV-1 RNA response using logistic and Cox regression, adjusting for sex, route of infection and pre-HAART more...
International Classification:
Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV
Categories:
HIV-1 - antiretroviral therapy
Geography:
Republic of Ireland and the United Kingdom
Aids,
Vol: 18 Page: 1915-24 September 2004
A. S. Walker; K. Doerholt; M. Sharland; D. M. Gibb
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