Irish Child Health Database - Peer Reviewed Papers
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Acute Disease
Your search returns 33 documents
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This study examined the incidence of 3'CBFbeta deletion in acute myeloid leukemia
Abstract:
Recent reports have shown that concomitant submicroscopic deletions can occur in association with chromosomal translocations/inversions in several leukemia subtypes. Detectable by fluorescence in situ hybridization (FISH), these losses of sequence include deletion of the 5' region of the ABL gene and the 3' region of BCR in chronic myeloid leukemia (CML) and acute lymphoblastic leukemia more...
International Classification:
Neoplasms - Malignant neoplasms - leukemia
Categories:
acute myeloid leukemia
Geography:
Republic of Ireland
Cancer Genet Cytogenet,
Vol: 162 Page: 122-6 October 2005
J. Kelly; N. J. Foot; E. Conneally; H. Enright; M. Humphreys; K. Saunders; M. J. Neat
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The aim of this study was to examine the frequency of a false negative result by sequencing studies in patients with hereditary pancreatitis and in healthy controls
Abstract:
BACKGROUND AND AIMS: Hereditary pancreatitis (HP) is a rare form of recurrent acute and chronic pancreatitis. Mutations in the cationic trypsinogen (protease serine 1, PRSS1) gene have been identified as causing HP. The R122H (previously known as R117H) mutation is the commonest and can be detected by a single and rapid polymerase chain reaction/restriction fragment length polymorphism more...
International Classification:
Diseases of the digestive system - Disorders of gallbladder, biliary tract and pancreas - hereditary pancreatitis
Categories:
hereditary pancreatitis;
Geography:
the United Kingdom
Gut,
Vol: 48 Page: 247-50 February 2001
N. Howes; W. Greenhalf; S. Rutherford; M. O'Donnell; R. Mountford; I. Ellis; D. Whitcomb; C. Imrie; B. Drumm; J. P. Neoptolemos
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The aim of this study was to examine the number of neonates attending the acute neonatal service out of hours and to identify the percentage of neonates treated as true emergency
Abstract:
BACKGROUND All neonates have free open access to the Baby Clinic at the maternity hospitals in Dublin for assessment of neonatal health issues. Through observation, however there is an increase in number of neonates attending the hospital outside the Baby Clinic hours. AIMS: To determine the number of neonates attending the acute neonatal service out of hours and to identify the more...
International Classification:
Health service provision
Categories:
acute neonatal service
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 175 Page: 62-5 2006 Oct-Dec
L. F. Wong; K. T. Lim; A. Twomey; J. Murphy
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This study aimed to develop and validate a logistic regression model to predict need for admission and length of hospital stay in children presenting to the Emergency Department with bronchiolitis
Abstract:
OBJECTIVE: To develop and validate a logistic regression model to predict need for admission and length of hospital stay in children presenting to the Emergency Department with bronchiolitis. SETTING: Two children's hospitals in Dublin, Ireland. METHODS: We reviewed 118 episodes of bronchiolitis in 99 children admitted from the Emergency Department. Those discharged within 24 h by a more...
International Classification:
Effectiveness of measurement tool - a logistic regression model to predict need for admission
Geography:
Republic of Ireland
Eur J Emerg Med,
Vol: 11 Page: 265-72 October 2004
P. Walsh; S. J. Rothenberg; S. O'Doherty; H. Hoey; R. Healy
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The aim of this study was to examine the rates of acute asthma admissions to Belfast's major children's emergency department.
Abstract:
The incidence of childhood asthma, a common condition, is on the rise worldwide. Despite reductions in the emission of urban smoke, traffic pollution is now a major worldwide problem. Belfast, Northern Ireland, is an old industrial city with major pollution problems. In this study, the authors investigated the rates of acute asthma admissions to Belfast's major children's emergency more...
International Classification:
Diseases of the respiratory system - Chronic lower respiratory diseases - asthma
Categories:
acute asthma admissions
Geography:
Northern Ireland
Arch Environ Health,
Vol: 56 Page: 234-41 2001 May-Jun
A. J. Thompson; M. D. Shields; C. C. Patterson
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The aim of this study was to examine rates of acute gastroenteritis in Northern Ireland and the Republic of Ireland
Abstract:
Most people with acute gastroenteritis do not seek medical care and are therefore not captured by routine surveillance. For this reason, population-based studies are needed to measure the burden of illness. A study of acute gastroenteritis in Northern Ireland and the Republic of Ireland surveyed 9,903 people by telephone over the 12-month period from December 2000 to November 2001. The more...
International Classification:
Diseases of the digestive system - acute gastroenteritis
Categories:
acute gastroenteritis
Geography:
Northern Ireland and the Republic of Ireland
Commun Dis Public Health,
Vol: 7 Page: 61-7 March 2004
E. Scallan; M. Fitzgerald; C. Collins; D. Crowley; L. Daly; M. Devine; D. Igoe; T. Quigley; T. Robinson; B. Smyth
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This study examined the presentation, complications and hospital course of acute mastoiditis and ascertain had long term otological problems.
Abstract:
Acute mastoiditis, a destructive bacterial infection of the mastoid bone and air cell system, is relatively uncommon today but remains a potentially serious condition. There is a lack of information in the literature regarding the long term otological problems that children may face following an episode of this condition. OBJECTIVES: Our aim was to examine the presentation, more...
International Classification:
Diseases of the ear and mastoid process - Diseases of middle ear and mastoid -mastoiditis
Categories:
mastoiditis
Geography:
Republic of Ireland
J Laryngol Otol,
Vol: 122 Page: 233-7 March 2008
F. Glynn; L. Osman; M. Colreavy; H. Rowley; T. P. Dwyer; A. Blayney
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This study examined acute renal damage in infants after first urinary tract infection
Abstract:
Urinary tract infection (UTI) is one of the most common causes of unexplained fever in neonates. The aim of this study was to determine the incidence of urinary tract anomalies and acute renal damage in neonates who presented with first urinary tract infection in the first 8 weeks of life. We reviewed the records of 95 infants, who were hospitalised with UTI during a 6-year period more...
International Classification:
Diseases of the genitourinary system - Other diseases of urinary system-urinary tract infection
Categories:
urinary tract infection
Geography:
Republic of Ireland
Pediatr Nephrol,
Vol: 17 Page: 503-5 July 2002
S. Cascio; B. Chertin; A. Yoneda; U. Rolle; J. Kelleher; P. Puri
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This article discusses acute retention of urine in babies with meningomyelocele
Geography:
Northern Ireland
Eur J Pediatr Surg,
Vol: 11 Suppl 1 Page: S40-1 December 2001
S. Brown; D. Patterson; D. Marshall
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The aim of this study was to examine ambulatory peadiatrics and improvements in patient care
International Classification:
Health service provision
Categories:
ambulatory peadiatrics; patient care
Geography:
Northern Ireland
Irish Medical Journal,
Vol: 94 Page: 186%N 6 2001
J. E. Bothwell; P. Sheridan; A. H. Bell
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This study examined pitfalls in the acute management of ankle fractures which were referred to a regional orthopaedic unit
Abstract:
OBJECTIVE: The aim of this study was to identify pitfalls in the acute management of ankle fractures which were referred to a regional orthopaedic unit. This unit provides orthopaedic services for the catchment area of the Waterford Emergency Department together with three additional emergency units in the south-eastern region of Ireland. METHODS: This is a retrospective study of all more...
International Classification:
Injury, poisoning and certain other consequences of external causes - fractures
Categories:
ankle fractures
Geography:
Republic of Ireland
Eur J Emerg Med,
Vol: 12 Page: 216-9 October 2005
C. Deasy; D. Murphy; G. C. McMahon; I. P. Kelly
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The aim of this study was to audit the collection of samples to investigate unexplained hypoglycaemia
Abstract:
BACKGROUND: A protocol exists for the collection of samples to investigate unexplained hypoglycaemia, termed the 'hypopack'. These packs are kept in Accident and Emergency departments and neonatal special care baby units throughout Northern Ireland and most wards of the Regional Children's Hospital. A retrospective audit of 107 hypopacks received between July 2001 and December 2003 more...
International Classification:
Endocrine, nutritional and metabolic diseases - unexplained hypoglycaemia
Categories:
unexplained hypoglycaemia
Geography:
Northern Ireland
Ann Clin Biochem,
Vol: 45 Page: 486-8 September 2008
T. F. Lang; D. Cardy; D. Carson; C. M. Loughrey; E. Hanna
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The aim of this review was to determine the efficacy and safety of chest physiotherapy in infants aged less than 24 months old with acute bronchiolitis
Abstract:
BACKGROUND: Acute bronchiolitis is the leading cause of medical emergencies during winter in children younger than two years of age. Chest physiotherapy is thought to assist infants in the clearance of secretions and to decrease ventilatory effort. OBJECTIVES: To determine the efficacy and safety of chest physiotherapy in infants aged less than 24 months old with acute bronchiolitis. more...
International Classification:
Systematic Review
Categories:
chest physiotherapy in infants
Geography:
Systematic Review
Cochrane Database Syst Rev,
2007
C. Perrotta; Z. Ortiz; M. Roque
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The aim of this review was to determine the benefit of systemic corticosteroids (oral, intravenous, or intramuscular) compared to placebo and inhaled steroids in acute paediatric asthma
Abstract:
BACKGROUND: Systemic corticosteroids are used routinely in the management of children with severe acute asthma. There is a lack of consensus regarding the agent, dose and route of corticosteroid administration. OBJECTIVES: To determine the benefit of systemic corticosteroids (oral, intravenous, or intramuscular) compared to placebo and inhaled steroids in acute paediatric asthma. SEARCH more...
International Classification:
Systematic Review
Categories:
systemic corticosteroids paediatric asthma
Geography:
Systematic Review
Cochrane Database Syst Rev,
2003
M. Smith; S. Iqbal; T. M. Elliott; M. Everard; B. H. Rowe
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This article discusses if pacifier (dummy) use results in an increased risk of ear infection (acute otitis media)
Abstract:
The aim of this review was to identify whether, in children under 2 years of age, pacifier (dummy) use results in an increased risk of ear infection (acute otitis media). The Cochrane Library, Medline, CINAHL and Embase databases were searched for cohort studies and randomised controlled trials that compared infants who used pacifiers with those who didn't or examined the effect of more...
Geography:
Republic of Ireland
Br J Community Nurs,
Vol: 7 Page: 206, 208-11 April 2002
S. Hanafin; P. Griffiths
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This case report discusses early continuous video-electroencephalography from 3 hours after birth in an infant with the characteristic clinical and radiologic features of acute near-total intrauterine asphyxia
Abstract:
The evolution of electroencephalographic changes after acute hypoxic-ischemic injury is poorly understood, as a clear time of insult is often absent and continuous electroencephalographic monitoring in the first 3 days after such injury has not been previously reported. Infants who suffer sudden profound asphyxia, often termed "acute near-total intrauterine asphyxia", have more...
International Classification:
Certain conditions originating in the perinatal period - Report
Categories:
near-total intrauterine asphyxia
Geography:
Republic of Ireland
Pediatr Neurol,
Vol: 35 Page: 52-6 July 2006
D. M. Murray; G. B. Boylan; C. A. Ryan; S. Connolly
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The aim of this study was to examine infants ranging in age from 3 weeks to 13 months who had shock of differing causes
Abstract:
We describe the findings from a group of five infants ranging in age from 3 weeks to 13 months who had shock of differing causes. In each case, sonographic evaluation of the abdomen revealed bilateral perirenal hyperechoic bands several millimeters thick, surrounding a thin, hypoechoic rim of fluid. The findings were identified during the acute phase of each child's illness and more...
International Classification:
Other - shock
Categories:
shock
Geography:
Northern Ireland
J Ultrasound Med,
Vol: 19 Page: 459-63 July 2000
A. Paterson; D. P. Frush; L. E. Sweeney; P. S. Thomas
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This study aimed to describe the development of a polyacrylamide gel electrophoresis method for the rapid separation of 16S rRNA PCR amplicons from aetiological agents of acute meningitis
Abstract:
AIMS: The aim of this study was to develop a polyacrylamide gel electrophoresis (PAGE) method for the rapid separation of 16S rRNA PCR amplicons from aetiological agents of acute meningitis. METHODS AND RESULTS: Blood samples from 40 patients with suspected acute meningococcal meningitis were examined for the presence of causal agents, including Neisseria meningitidis employing two more...
International Classification:
Effectiveness of measurement tool - polyacrylamide gel electrophoresis
Categories:
polyacrylamide gel electrophoresis; acute meningitis
Geography:
Northern Ireland
J Appl Microbiol,
Vol: 94 Page: 197-206 2003
J. Xu; B. C. Millar; J. E. Moore; K. Murphy; H. Webb; A. J. Fox; M. Cafferkey; M. J. Crowe
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This study examined the outcome of a policy advocating urgent exploration for acute scrotal pain
Abstract:
BACKGROUND: Acute scrotal pain is a common urological emergency. Urgent exploration is the standard means of management, as no investigation can confidently exclude torsion of testis from the differential diagnoses. In our department, all patients up to the age of 40 years, presenting with acute scrotal pain undergo emergency scrotal exploration. AIM: This study assesses the outcome of more...
International Classification:
Procedure - treatment of acute scrotal pain
Categories:
acute scrotal pain
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 170 Page: 181-2 2001 Jul-Sep
P. K. Hegarty; E. Walsh; M. O. Corcoran
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The aim of this study was to examine the incidence of acute pancreatitis by examining emergency admissions to acute public hospitals over an 8-year period
Abstract:
OBJECTIVE: To investigate trends in the incidence of acute pancreatitis by examining emergency admissions to acute public hospitals over an 8-year period; to compare trends for alcohol-related pancreatitis admissions with biliary tract-related admissions and to profile the patients admitted with an acute pancreatitis diagnosis. METHODS: All in-patient emergency admissions for which an more...
International Classification:
Diseases of the digestive system - Disorders of gallbladder, biliary tract and pancreas - pancreatitis
Categories:
acute pancreatitis
Geography:
Republic of Ireland
J Public Health (Oxf),
Vol: 29 Page: 398-404 December 2007
A. O'Farrell; S. Allwright; D. Toomey; D. Bedford; K. Conlon
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The aim of this study was to screen for genomic imbalances in patients with acute leukaemia using conventional and molecular and fluorescence in situ hybridisation methods
Abstract:
AIMS: To screen for genomic imbalances in patients with acute leukaemia using conventional (G-banding) and molecular (comparative genomic hybridisation (CGH) and fluorescence in situ hybridisation (FISH)) methods to determine whether an integrative screening approach increases abnormality detection rate. METHODS: G-banded analysis was performed on unstimulated bone marrow (BM) or more...
International Classification:
Neoplasms - Malignant neoplasms - leukaemia
Categories:
leukaemia (acute)
Geography:
Northern Ireland
J Clin Pathol,
Vol: 61 Page: 903-8 August 2008
P. McGrattan; S. Campbell; R. Cuthbert; F. G. Jones; M. F. McMullin; M. Humphreys
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This study examined intracranial complications of acute frontal sinusitis
Abstract:
Despite advances in the diagnosis and treatment of acute frontal sinusitis, there is still significant occurrence of intracranial complications. Urgent surgical evacuation of any intracranial collection is required; however, the surgical management of the associated sinusitis remains controversial. Ten patients presented to this department over a 12-month period with subdural empyema more...
International Classification:
Diseases of the respiratory system - Acute upper respiratory infections - sinusitis
Categories:
sinusitis
Geography:
Republic of Ireland
Clin Otolaryngol Allied Sci,
Vol: 26 Page: 452-7 December 2001
E. E. Lang; A. J. Curran; N. Patil; R. M. Walsh; D. Rawluk; M. A. Walsh
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The aim of this study was to examine the status of the enteric nervous system in normal and in inflamed appendixes
Abstract:
OBJECTIVE: The pathogenesis of appendicitis remains poorly understood. However, there is increasing evidence of involvement of the enteric nervous system in immune regulation and in inflammatory responses. This study was set up to characterize the status of the enteric nervous system in normal and in inflamed appendixes. METHODS: S100- and 2',2'-cyclic nucleotide 3' more...
International Classification:
Diseases of the digestive system - Diseases of appendix - appendixes
Categories:
enteric nervous system; inflamed appendixes
Geography:
Republic of Ireland
Arch Pathol Lab Med,
Vol: 124 Page: 1429-33 October 2000
S. Xiong; P. Puri; L. Nemeth; D. S. O'Briain; D. J. Reen
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These case reports discuss two cases of osteomyelitis of the ischiopubic synchondrosis and describe findings on radiographs, isotope bone scan, computed tomograph and magnetic resonance imaging
Abstract:
Osteomyelitis of the ischiopubic synchondrosis in children is not rare and presents a diagnostic problem because of the diversity of presentation and the deceptive nature of symptoms. Radiological assessment is extremely difficult because of the variation in normal ossification on radiography and normal physiological uptake on radioisotope bone scan. We present two cases of more...
International Classification:
Diseases of the musculoskeletal system and connective tissue - Report
Categories:
osteomyelitis
Geography:
Republic of Ireland
Skeletal Radiol,
Vol: 33 Page: 176-80 March 2004
A. Iqbal; D. McKenna; R. Hayes; D. O'Keeffe
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The aim of this study was to describe patterns of asthma admissions in children
Abstract:
Admissions for childhood asthma have declined over the past 10 years in the U.K. The reasons for this decline are not known. There are few published data on Irish children. The study was completed in a paediatric unit in a regional general hospital, with a stable urban/rural catchment population of approximately 45,000 children under 15 years. H.I.P.E. data on paediatric asthma more...
International Classification:
Diseases of the respiratory system - Chronic lower respiratory diseases - asthma
Categories:
asthma
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 407-9 March 2007
A. Shabu; M. Carr; E. Crushell; B. G. Loftus
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This study evaluated the performance of the Trellis-8 isolated thrombolysis catheter during single-session pharmacomechanical thrombectomy combined with low-dose thrombolysis with tissue plasminogen activator in the treatment acute deep vein thrombosis
Abstract:
PURPOSE: To evaluate the performance of the Trellis-8 isolated thrombolysis catheter during single-session pharmacomechanical thrombectomy (PMT) combined with low-dose thrombolysis with tissue plasminogen activator (TPA) in the treatment of patients with acute deep vein thrombosis (DVT) and multiple comorbidities. MATERIALS AND METHODS: Retrospective analysis was performed of 19 more...
International Classification:
Procedure - treatment of acute deep vein thrombosis
Categories:
acute deep vein thrombosis
Geography:
Republic of Ireland
J Vasc Interv Radiol,
Vol: 18 Page: 715-24 June 2007
G. J. O'Sullivan; D. G. Lohan; N. Gough; C. G. Cronin; S. T. Kee
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This case report discusses an unusual case where imaging revealed extensive pneumatosis intestinalis and portal venous gas in a patient with acute appendicitis
Abstract:
Pneumatosis Intestinalis in association with portal venous gas is a very rare finding in children and young adults. When present, it is typically associated with bowel infarction and carries a poor prognosis. We present an extremely unusual case where imaging revealed extensive pneumatosis intestinalis and portal venous gas in a patient with acute appendicitis. more...
International Classification:
Diseases of the digestive system - Report
Categories:
acute appendicitis
Geography:
Republic of Ireland
Australas Radiol,
Vol: 51 Spec No. Page: B137-9 October 2007
D. J. Tuite; A. Byrne; E. Colhoun; W. C. Torreggiani
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The aim of this study was to examine the development of real-time PCR assays for the detection of group F adenovirus, rotavirus A, and rotavirus C from stool specimens
Abstract:
Viral pathogens are the most common cause of gastroenteritis in developed countries. Human rotavirus and adenovirus infections are major causes of acute outbreaks and sporadic cases of gastroenteritis, occurring primarily among children less than 2 years of age. Patient hospitalization is often required, with enormous infection control implications. This work describes the development more...
International Classification:
International committee on Taxonomy of Viruses - adenovirus & rotavirus
Categories:
real-time PCR assays; - group F adenovirus & rotavirus A &C
Geography:
Republic of Ireland
J Clin Microbiol,
Vol: 44 Page: 3189-95 September 2006
C. Logan; J. J. O'Leary; N. O'Sullivan
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This study examined the use of recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high responding inhibitors
Abstract:
The management of acute and surgical bleeding episodes in children with severe factor VIII or IX deficiency who develop high responding inhibitors presents a major therapeutic challenge to clinicians. Recombinant factor VIIa (rVIIa) is an effective, reliable and safe treatment that can be used to treat acute bleeding episodes prior to commencing an immune tolerance programme and to more...
International Classification:
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - Coagulation defects, purpura and other haemorrhagic conditions - haemophilia
Categories:
haemophilia
Geography:
Republic of Ireland and the United Kingdom
Br J Haematol,
Vol: 116 Page: 632-5 March 2002
N. O'Connell; C. Mc Mahon; J. Smith; K. Khair; I. Hann; R. Liesner; O. P. Smith
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The aim of this study was to examine the incidence of acute-onset presumed infectious endophthalmitis following cataract surgery in the United Kingdom and provide epidemiological data on presentation, management, microbiology, and endophthalmitis cases
Abstract:
AIMS: To estimate the incidence of acute-onset presumed infectious endophthalmitis (PIE) following cataract surgery in the UK and provide epidemiological data on the presentation, management, microbiology, and outcome of cases of endophthalmitis. METHODS: Cases were identified prospectively by active surveillance through the British Ophthalmological Surveillance Unit reporting card more...
International Classification:
Diseases of the eye and adnexa - Disorders of vitreous body and globe - endophthalmitis
Categories:
endophthalmitis
Geography:
the United Kingdom
Eye,
Vol: 18 Page: 580-7 June 2004
S. Kamalarajah; G. Silvestri; N. Sharma; A. Khan; B. Foot; R. Ling; G. Cran; R. Best
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This study reviewed the epidemiology, severity and management of trauma admissions at the national neurosurgical teaching hospital.
Abstract:
OBJECTIVE: To review and examine the epidemiology, severity and management of trauma admissions at the national neurosurgical teaching hospital. METHODS: An extensive audit of volume, type and severity of injury and the management requirements of the trauma population admitted to the hospital. RESULTS: The vast majority of severely injured patients were referred from outside the more...
International Classification:
Other - trauma admissions
Categories:
trauma admissions
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 176 Page: 15-21 March 2007
M. C. Fitzgibbon; M. Donnelly; J. P. Phillips; P. Murray; R. Moran; D. J. Bouchier-Hayes
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This article discusses the transfusion of blood components to infants under 4 months
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: suppl 1-24 following 496 June 2007
J. M. O'Riordan; J. Fitzgerald; O. P. Smith; J. Bonnar; W. A. Gorman
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This article discusses reviews the role of radiology in urinary tract infections
Abstract:
Urinary tract infections (UTIs) are a common cause of morbidity in children. The distinction between upper and lower tract UTI is clinically difficult but important, as permanent renal damage can occur when the UTI involves the kidneys. Children with a history of UTI need investigated promptly and thoroughly. The goal of imaging in UTI is to aid in the diagnosis of acute pyelonephritis, more...
Geography:
Northern Ireland
Eur Radiol,
Vol: 14 Suppl 4 Page: L89-100 March 2004
A. Paterson
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