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Irish Child Health Database - Peer Reviewed Papers

Database Search

Interleukin-2/ biosynthesis

Your search returns 1 documents

• 1.   Elevated expression of IL2 is associated with increased infiltration of CD8+ T cells in biliary atresia

  The aim of this study was to characterize the inflammation in biliary atresia by quantifying lymphocyte density and expression of TH1 cytokines such as IL2 and tumor necrosis factor alpha (TNF-alpha) in liver biopsies using qrt-PCR

  

  Abstract:

  AIM OF STUDY: Lymphocyte-mediated inflammation within the liver and bile ducts has been proposed as a potential mechanism in the pathogenesis of biliary atresia (BA). Recent reports have suggested that BA is associated with upregulation of TH1-type inflammatory cytokines. Quantitative real-time polymerase chain reaction (qrt-PCR) is a useful tool to assess immune cell density and more...

  International Classification:

  Congenital malformations of the digestive system - Other congenital malformations of the digestive system - biliary atresia

  Categories:

  biliary atresia

  Geography:

  Republic of Ireland

  J Pediatr Surg, Vol: 41 Page: 300-5 February 2006
  M. Shinkai; T. Shinkai; P. Puri; M. D. Stringer

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