About Us
- Introduction
- Contact us
- Customer Service
- DCYA Strategy
- Designated Public Officials
- Framework of Assignments
- Organisation Structure
- State Boards
Minister for Children and Youth Affairs
Childcare
- What we do
- Affordable Childcare Scheme
- Free Pre-School year in Early Childhood Care and Education (ECCE) Programme
- Community Childcare Subvention (CCS) Programme
- Training and Employment Childcare (TEC) Programmes
- City/County Childcare Committees (CCCs)
- Childcare Regulations
- Pre-School Inspections
- Childminders
- Early Years Education-Focused Inspections
- Information for Parents
- Qualifications
- Childcare Initiatives
Tusla
- Overview
- Contact Tusla
- Board and CEO
- Governance and Performance
Children In Care
- Introduction
- Pathway Into Care
- What Can you Expect When in Care?
- Role of Social Workers and Gardaí
- Aftercare
- Legislation, Regulations and Standards
- Reports, Data and Fact Sheets
Participation
- What we do
- Comhairle na nÓg
- Dáil na nÓg
- Consultations
- National Strategy on Participation of Children in Decision Making
- Children and Young People's Participation Support Team
- Participation Hub
Play, Recreation & Culture
- Play & Recreation
- Culture
Children and Young People's Participation Hub
- Children's Participation Hub Database
- Developing the Hub
Child Welfare and Protection
- What We Do
- North South Ministerial Council
- FAQ
Children First
- Overview & FAQs
- Children First Legislation
- Children First Guidance
- Children First Implementation
- DCYA Child Protection Policy
Adoption
Irish Youth Justice Service
Youth Affairs
- What We Do
- Funding
- Programmes
- Policies & Initiatives
- Young Voices!!
- Further Information
Area Based Childhood (ABC) Programme
- Overview
Mother and Baby Homes Investigation
Children and Young People's Services Committees (CYPSC)
- CYPSC
Reform of Guardian ad litem Arrangements
Quality and Capacity Building Initiative
- QCBI
Better Outcomes, Brighter Futures
- Better Outcomes, Brighter Futures
- Advisory Council
- Publications
- Survey
Legislation
International Framework
- UNCRC
- EU and Council of Europe
Research
- What we do
- Children's Funded Research Programme
- National Set of Child Well Being Indicators
- Measuring Child Well Being
- State of the Nation's Children Report
- Research Placement Programme
- Research Scholarship Programme
- Research Briefing Notes
- FAQ
Growing Up in Ireland
- DCYA/IRC Scholarship
- Growing Up in Ireland Phase 1
- Growing Up In Ireland Publications
National Research and Data Strategy
- Background to the Strategy
- Action Plan Updates
- Inventory of Data Sources
- Research Development Initiative Briefing Notes
Children's Database
Financial Information
- Prompt Payments
- Purchase Orders for €20,000 or above
- Purchasing & Procurement Information
Freedom of Information

Irish Child Health Database - Peer Reviewed Papers

Database Search

Irish Child Health Database » » P » Protein C/ pharmacokinetics/therapeutic use

Protein C/ pharmacokinetics/therapeutic use

Your search returns 1 documents

1. An open-label study of the role of adjuvant hemostatic support with protein C replacement therapy in purpura fulminans-associated meningococcemia

The aim of the study was to conduct an open-label prospective study assessing the efficacy of activated protein C replacement therapy in patients with severe meningococcal septicemia, purpura fulminans, and multiorgan failure

Abstract:

Activated protein C (APC) is a natural anticoagulant that plays a pivotal role in coagulation homeostasis. Severe inherited or acquired deficiency results in a clinical syndrome called purpura fulminans. In addition, APC also appears to have potent cytokine-modifying properties and is protective in animal models of sepsis. The dual functional properties of APC are particularly relevant more...

International Classification:

Certain infectious and parasitic diseases - Other bacterial diseases - meningococcal disease

Categories:

severe meningococcal septicemia

Geography:

Republic of Ireland

Blood, Vol: 96 Page: 3719-24 December 2000
B. White; W. Livingstone; C. Murphy; A. Hodgson; M. Rafferty; O. P. Smith

[Preview] [Read]