Irish Child Health Database - Peer Reviewed Papers
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The aim of this study was to audit the incidence, type of injury, medical consequences and outcome of patients with stab or gunshot wounds presenting to the Mid-Western Regional Hospital, Limerick,
Abstract:
BACKGROUND: According to a recent study in Cardiff, the incidence of stab wounds is 14 per 100,000 population per annum. No such figures are available for Ireland. AIM: To evaluate the incidence, type of injury, medical consequences and outcome of patients with stab or gunshot wounds presenting to the Mid-Western Regional Hospital, Limerick, over a 12 month period. METHOD: A more...
International Classification:
External causes of morbidity and mortality treatment - Accidents - stab or gunshot wounds
Categories:
stab or gunshot wounds
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 173 Page: 102-4 2004 Apr-Jun
J. Shabbir; C. O. McDonnell; J. B. O'Sullivan; K. Cahill; A. Moore; R. Raminlagan; G. Quinn; P. A. Grace
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This study examined the incidence of 3'CBFbeta deletion in acute myeloid leukemia
Abstract:
Recent reports have shown that concomitant submicroscopic deletions can occur in association with chromosomal translocations/inversions in several leukemia subtypes. Detectable by fluorescence in situ hybridization (FISH), these losses of sequence include deletion of the 5' region of the ABL gene and the 3' region of BCR in chronic myeloid leukemia (CML) and acute lymphoblastic leukemia more...
International Classification:
Neoplasms - Malignant neoplasms - leukemia
Categories:
acute myeloid leukemia
Geography:
Republic of Ireland
Cancer Genet Cytogenet,
Vol: 162 Page: 122-6 October 2005
J. Kelly; N. J. Foot; E. Conneally; H. Enright; M. Humphreys; K. Saunders; M. J. Neat
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This study examined patients with phaeochromocytoma
Abstract:
Thirty three patients with phaeochromocytomas had surgery in St. Vincent's Hospital between 1950 and 1997. 32 patients had hypertension, 32 had palpitations and 30 had excessive sweating. All patients had at least one of these cardinal symptoms. Diagnostic tests changed over this period. In the early cases the phentolamine test was used, later diagnosis was confirmed by measurement of more...
International Classification:
Neoplasms - Malignant neoplasms - phaeochromocytoma
Categories:
phaeochromocytoma
Geography:
Republic of Ireland
Ir Med J,
Vol: 94 Page: 200-3 2001 Jul-Aug
T. O'Halloran; G. McGreal; E. McDermott; N. O'Higgins
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The aim of this study was to evaluate long-term outcomes of children who had been inpatients in a child psychiatry unit
Abstract:
The purpose of this study was to evaluate long-term outcomes of children who had been inpatients in a child psychiatry unit. Fifty children, who were consecutive admissions to a Dublin inpatient child psychiatry unit between November 1978 and July 1980, were followed up 16 years later. We obtained some direct information on 33 subjects; of these, 4 subjects had died and 11 subjects more...
International Classification:
Mental and behavioural disorders - psychiatry
Categories:
psychiatry outcomes
Geography:
Republic of Ireland
Eur Child Adolesc Psychiatry,
Vol: 9 Page: 46-53 March 2000
E. Healy; M. Fitzgerald
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The aim of this study was to compare the educational and employment experiences of teenage mothers and match peers from a similar social background
Abstract:
Teenage motherhood has been linked with poor health, poor educational attainment, poor employment prospects and socio-economic deprivation. Much of the evidence has come from large surveys and the nature of these inter-relationships remains unclear. A case-control study was designed to compare the educational and employment experiences of teenage mothers with those of an age matched more...
International Classification:
Other - Teenage mothers
Categories:
educational; employment; - teenage mothers
Geography:
Republic of Ireland
Int J Adolesc Med Health,
Vol: 14 Page: 117-23 2002 Apr-Jun
T. Bradley; M. E. Cupples; H. Irvine
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The aim of this study was to audit the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome
Abstract:
The objective of the investigation was to determine the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome. A prospective audit of patients with complex hydrocephalus undergoing Hakim programmable valve implantation between 1989 and 1994 in the United Kingdom and Ireland, was followed-up for a minimum of 5 more...
International Classification:
Procedure - Hakim valve implants
Categories:
Hakim valve implants
Geography:
Republic of Ireland and the United Kingdom
Br J Neurosurg,
Vol: 14 Page: 535-42 December 2000
A. D. Kay; A. J. Fisher; C. O'Kane; H. K. Richards; J. D. Pickard
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The aim of the study was to establish common, symptom-based case definition for gastroenteritis by comparing across four counteries
Abstract:
National studies determining the burden of gastroenteritis have defined gastroenteritis by its clinical picture, using symptoms to classify cases and non-cases. The use of different case definitions has complicated inter-country comparisons. We selected four case definitions from the literature, applied these to population data from Australia, Canada, Ireland, Malta and the United more...
International Classification:
Certain infectious and parasitic diseases - Intestinal infectious diseases - gastroenteritis
Categories:
gastroenteritis
Geography:
United States of America
Epidemiology and Infection,
Vol: 136 Page: 886-894 2008
S. E. Majowicz; G. Hall; E. Scallan; G. K. Adak; C. Gauci; T. F. Jones; S. O'Brien; O. Henao; P. Sockett
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The aim of this study was to examine carotenoids in human and formulae milks
Abstract:
BACKGROUND: Two carotenoids, lutein and zeaxanthin are found in the retinal pigment epithelium of the eye where they are believed to protect it against oxidative and light damage. The amounts of these carotenoids consumed by premature infants are not known. OBJECTIVE: The objective of the investigation was to measure these carotenoids in human and formulae milks. DESIGN: In all, 28 more...
International Classification:
Breastfeeding +/- formulae milk
Categories:
formulae milks
Geography:
Northern Ireland
Eur J Clin Nutr,
Vol: 58 Page: 90-7 January 2004
V. C. Jewell; C. B. Mayes; T. R. Tubman; C. A. Northrop-Clewes; D. I. Thurnham
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The aim of this study was to examine surgical impression, histological findings and microbiological results at open appendicectomy
Abstract:
There is no accurate predictor of complications following open appendicectomy. Surgical impression, histological findings and peritoneal culture swabs have been used. The value of peritoneal culture swab was assessed in this study. All patients undergoing open appendicectomy between January 2003 and December 2005 were included in the study. During the 24-Month period, 952 patients more...
International Classification:
Diseases of the digestive system - Diseases of appendix - appendicectomy
Categories:
appendicectomy
Geography:
Republic of Ireland
Irish Medical Journal,
Vol: 100 Page: 2007
G. Colleran; H. Heneghan; K. J. Sweeney; M. J. Kerin
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The aim of the study was to examine traditional and otic capsule classification system of temporal bone fractures for clinical relevance
Abstract:
Objectives: To compare the traditional and otic capsule classification system of temporal bone fractures for clinical relevance. Design: A retrospective review of all patients with a radiological diagnosis of a skull-base fracture over a 5-year period. Setting: All patients were seen at Beaumont Hospital, the national tertiary referral centre for Neuro-otology. Participants: Patients more...
International Classification:
Injury, poisoning and certain other consequences of external causes - fractures
Categories:
temporal bone fractures
Geography:
Republic of Ireland
Clinical Otolaryngology,
Vol: 31 Page: 287-291 2006
M. A. Rafferty; R. Mc Conn Walsh; M. A. Walsh
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The aim of this study was to examine the linguistic anthropology which underpins the language dynamics of two Gaeltacht (Irish-speaking) areas
Abstract:
This paper presents an analysis of the linguistic anthropology which underpins the language dynamics of two Gaeltacht (Irish-speaking) areas, Ros Muc in Conamara, Co. Galway and Rath Cairn in Co. Meath. This research highlights what could be considered a socio-linguistic paradox: the community (Rath Cairn) which engages more vigorously in language maintenance endeavors, and exhibits a more...
International Classification:
Anthropology or ethnographic-language
Categories:
linguistic anthropology; language dynamics
Geography:
Republic of Ireland
Coll Antropol,
Vol: 28 Suppl 1 Page: 73-81 2004
C. O. Giollagain
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In this study a retrospective analysis of all consecutive helicopter transfers to the Beaumont neurosurgical unit was performed over a two year period from January 1994 to December 1996.
Abstract:
A retrospective analysis of all consecutive helicopter transfers to the Beaumont neurosurgical unit was performed over a two year period from January 1994 to December 1996. There were 55 transfers, 55% of which were for trauma patients. Sixty two per cent were intubated prior to transfer. The mean length of stay at the referring hospital prior to transfer was 12.25 hours (range 3-98 more...
International Classification:
Economic- Health service provision-transport
Categories:
helicopter transfers
Geography:
Republic of Ireland
Ir Med J,
Vol: 93 Page: 50-1 2000 Mar-Apr
R. Dardis; G. Roberts; J. Phillips
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The aim of this study was to accelerate the identification of susceptibility genes in diabetic nephropathy using genome-wide fluorescence-based DNA microsatellite
Abstract:
In an effort to accelerate the identification of susceptibility genes in diabetic nephropathy, the first genome-wide fluorescence-based DNA microsatellite (n=6000) association screen was performed, using pools of genomic DNA derived from Irish patients with (cases; n=200) and without (controls; n=200) type 1 diabetic nephropathy. Allele image profiles were generated for 5353 (89.2%) more...
International Classification:
Endocrine, nutritional and metabolic diseases - diabetic nephropathy
Categories:
susceptibility genes; -diabetic nephropathy
Geography:
Northern Ireland
J Am Soc Nephrol,
Vol: 17 Page: 831-6 March 2006
A. J. McKnight; A. P. Maxwell; S. Sawcer; A. Compston; E. Setakis; C. C. Patterson; H. R. Brady; D. A. Savage
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The aim of this study was to examine a genome-wide linkage scan using 4710 single-nucleotide polymorphisms in families with more then one member with Vesicoureteric reflux
Abstract:
BACKGROUND: Vesicoureteric reflux (VUR) is the retrograde flow of urine from the bladder into the ureters. It is the most common urological anomaly in children, and a major cause of end-stage renal failure and hypertension in both children and adults. VUR is seen in approximately 1-2% of Caucasian newborns and is frequently familial. Objective and METHODS: In order to search for genetic more...
International Classification:
Other - genome-wide linkage scan
Categories:
genome-wide linkage scan
Geography:
Republic of Ireland
J Med Genet,
Vol: 44 Page: 710-7 November 2007
H. Kelly; C. M. Molony; J. M. Darlow; M. E. Pirker; A. Yoneda; A. J. Green; P. Puri; D. E. Barton
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This article discusses a campaign to eradicate Meningitis C in Ireland
Abstract:
The new campaign to eradicate meningitis C marks Ireland's biggest ever immunisation programme, writes Moira Cassidy. more...
Geography:
Republic of Ireland
World of Irish Nursing,
Vol: 9 Page: 17-17 2001
M. Cassidy
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The aim of this study was to investigate the relationship between stage of epiphyseal union at the knee joint and chronological age in a modern Irish population
Abstract:
Characteristic changes during epiphyseal union provide a skeletal age, which when compared with age-based standards provides an estimation of chronological age. Currently there are no data on epiphyseal union for the purposes of age estimation specific to an Irish population. This cross-sectional study aims to investigate the relationship between stage of epiphyseal union at the knee more...
International Classification:
Growth and development - epiphyseal union
Categories:
epiphyseal union
Geography:
Republic of Ireland
J Anat,
Vol: 212 Page: 198-209 February 2008
J. E. O'Connor; C. Bogue; L. D. Spence; J. Last
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The aim of this study was to examine the frequency of a false negative result by sequencing studies in patients with hereditary pancreatitis and in healthy controls
Abstract:
BACKGROUND AND AIMS: Hereditary pancreatitis (HP) is a rare form of recurrent acute and chronic pancreatitis. Mutations in the cationic trypsinogen (protease serine 1, PRSS1) gene have been identified as causing HP. The R122H (previously known as R117H) mutation is the commonest and can be detected by a single and rapid polymerase chain reaction/restriction fragment length polymorphism more...
International Classification:
Diseases of the digestive system - Disorders of gallbladder, biliary tract and pancreas - hereditary pancreatitis
Categories:
hereditary pancreatitis;
Geography:
the United Kingdom
Gut,
Vol: 48 Page: 247-50 February 2001
N. Howes; W. Greenhalf; S. Rutherford; M. O'Donnell; R. Mountford; I. Ellis; D. Whitcomb; C. Imrie; B. Drumm; J. P. Neoptolemos
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The aim of this study was to examine new anthropomorphic parameters as indicators of Cephalopelvic disproportion
Abstract:
Cephalopelvic disproportion (CPD) is a recognised obstetric problem with potential risk to both mother and infant. Identification of those mothers at risk of CPD is difficult and has concentrated in the past on such measurements as maternal shoe size and height. Our objective in this study was to examine new anthropomorphic parameters as indicators of CPD. This was a case controlled more...
International Classification:
Pregnancy, childbirth and the puerperium - cephalopelvic disproportion
Categories:
anthropomorphic parameters; - Cephalopelvic disproportion
Geography:
Republic of Ireland
J Obstet Gynaecol,
Vol: 23 Page: 27-9 January 2003
G. Connolly; C. Naidoo; R. M. Conroy; P. Byrne; P. McKenna
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The aim of this study was to examine if Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma gene could play a role in birth weight and duration of gestation
Abstract:
The links between preterm birth, low birth weight, and adult vascular/metabolic morbidity remain unclear. Genetic susceptibility of babies related to these three conditions might contribute to this long-term association. We tested whether the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma (PPARG) gene could play a role in birth weight and duration of more...
International Classification:
Pregnancy, childbirth and the puerperium - birth weight
Categories:
birth weight; duration of gestation
Geography:
Northern Ireland
Diabetes,
Vol: 56 Page: 494-498 2007
A. Meirhaeghe; C. A. G. Boreham; L. J. Murray; F. Richard; G. Davey Smith; I. S. Young; P. Amouyel
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The aim of this study was to assess the health economics of realtime teledermatology compared with conventional care: an urban versus rural perspective
Abstract:
A randomized controlled trial was carried out to measure the cost-effectiveness of realtime teledermatology compared with conventional outpatient dermatology care for patients from urban and rural areas. One urban and one rural health centre were linked to a regional hospital in Northern Ireland by ISDN at 128 kbit/s. Over two years, 274 patients required a hospital outpatient more...
International Classification:
Evaluation of the effectiveness of teledermatology v. conventional assessment
Categories:
teledermatology v. conventional care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 7 Page: 108-18 2001
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; C. Evans; N. Hicks; P. Jacklin; H. E. Lotery; C. Mathews; J. Paisley; P. Reid; K. Steele; R. Wootton
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The aim of this study was to assess realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial
Abstract:
The clinical effectiveness of realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial. A total of 204 patients took part--102 patients were randomized to the realtime teledermatology consultation, 96 of whose cases were also referred using a store-and-forward technique, and 102 to the more...
International Classification:
Evaluation of the effectiveness of two treatments - in dermatological care
Categories:
dermatological care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 6 Suppl 1 Page: S1-3 2000
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; N. Hicks; H. E. Lotery; C. Mathews; J. Paisley; K. Steele; R. Wootton
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The aim of this study was to assess the effect of introducing two biophysical ultrasound examinations in a low-risk antenatal population
Abstract:
OBJECTIVE: To evaluate the effect of introducing two biophysical ultrasound examinations in a low-risk antenatal population.Scans were performed at 30-32 weeks' gestation and 36-37 weeks' gestation. METHODS: Scans assessed placental maturity, amniotic fluid volume, and estimated fetal weight. One thousand nine hundred ninety-eight low-risk patients were randomized at 30 weeks' gestation more...
International Classification:
Evaluation of the effectiveness of procedures - two biophysical ultrasound
Categories:
ultrasound examinations in a a low-risk antenatal population
Geography:
Northern Ireland
Obstet Gynecol,
Vol: 101 Page: 626-32 April 2003
D. McKenna; S. Tharmaratnam; S. Mahsud; C. Bailie; A. Harper; J. Dornan
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The aim of this study was to examine the number of factors associated with the occurrence of suicide
Abstract:
This study reports on 60 cases of suicide in Londonderry, Northern Ireland from January 2000 to December 2005. The research focused on a number of factors associated with the occurrence of suicide. These included age, gender, employment status, method used and possible predisposing factors. Additionally, the seasonality of occurrence was also investigated. Notably, over the period of more...
International Classification:
External causes of morbidity and mortality - Intentional self-harm - suicide
Categories:
suicide
Geography:
Northern Ireland
J Forensic Leg Med,
Vol: 15 Page: 148-57 April 2008
A. Burns; E. Goodall; T. Moore
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The aim of this study was to benchmark the psychological state and physical rehabilitation of patients who have sustained limb loss as a result of terrorist activity in Northern Ireland
Abstract:
OBJECTIVE: To benchmark the psychological state and physical rehabilitation of patients who have sustained limb loss as a result of terrorist activity in Northern Ireland and to determine their satisfaction with the period of primary prosthetic rehabilitation and the artificial limb. METHOD: All patients who sustained limb loss as a result of the Troubles and were referred to our more...
International Classification:
War, violence and conflict
Categories:
psychological state as a result of terrorist activity
Geography:
Northern Ireland
Disabil Rehabil,
Vol: 28 Page: 797-801 June 2006
L. Graham; R. C. Parke; M. C. Paterson; M. Stevenson
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The aim of this study was to compare Irish asylum seekers to other General Medical Scheme patients possessing Irish citizenship in terms of their utilisation of GP services, morbidity patterns and consultation outcomes
Abstract:
To compare Irish asylum seekers to other General Medical Scheme (GMS) patients possessing Irish citizenship in terms of their utilisation of GP services, morbidity patterns and consultation outcomes. A retrospective 1 year study on patient records in two Galway City practices was performed. All asylum seekers who were patients of the two practices were compared with two controls each more...
International Classification:
Health service provision
Categories:
morbidity patterns; consultation outcomes; -asylum seekers
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 461-4 May 2007
J. D. McMahon; A. Macfarlane; G. E. Avalos; P. Cantillon; A. W. Murphy
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The aim of this study was to examine the incidence and causes of sudden cardiac death in Dublin city in the 10-year period from 1st January 1993 to 31st December 2002
Abstract:
CRY (Cardiac Risk in the Young) is a registered Irish charity established by parents who are bereaved as a result of sudden cardiac death. The aim of this study is to establish the incidence and causes of sudden cardiac death in Dublin city in the 10-year period from 1st January 1993 to 31st December 2002. All sudden cardiac deaths in the under 35-year age group which were reported to more...
International Classification:
Diseases of the circulatory system - Other forms of heart disease - sudden cardiac death
Categories:
sudden cardiac death
Geography:
Republic of Ireland
Ir Med J,
Vol: 98 Page: 232-5 September 2005
F. Quigley; M. Greene; D. O'Connor; F. Kelly
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The aim of this study was to examine the incidence, causes, associated factors, and pathological findings in people who died while exercising
Abstract:
BACKGROUND: Sudden death in sport is rare, but when it occurs the effects are devastating. There have not been any reports to date describing the frequency and causes of sudden death in sport in the Republic of Ireland. AIM: To describe the incidence, possible causes, associated factors, and pathological findings in people who died while exercising in the Republic of Ireland in the 10 more...
International Classification:
Deaths - while exercising
Categories:
death while exercising
Geography:
Republic of Ireland
Br J Sports Med,
Vol: 34 Page: 258-61 August 2000
F. Quigley
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The aim of this study was to examine the prevalence and frequency of stereotypy, self-injurious behaviour and aggression in children and adults with Cri du Chat syndrome
Abstract:
The aim of the present study was to determine the prevalence and frequency of stereotypy, self-injurious behaviour (SIB), and aggression in children and adults with Cri du Chat syndrome (CCS), and to investigate the relationship between SIB, aggressive behaviour and stereotypy in these individuals. Sixty-six families of children and adults diagnosed with CCS completed the Behaviour more...
International Classification:
External causes of morbidity and mortality - Intentional self-harm - self-injury
Categories:
self-injurious behaviour; Cri du Chat syndrome
Geography:
Northern Ireland
J Intellect Disabil Res,
Vol: 46 Page: 133-40 February 2002
M. S. Collins; K. Cornish
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This study aimed to review and document the changing patterns in diagnosis, causes and treatment of bacterial infections of the central nervous system in a national neurosurgical unit
Abstract:
OBJECTIVES: To review and document the changing patterns in diagnosis, causes and treatment of bacterial infections of the central nervous system (CNS) in a national neurosurgical unit only in patients from whom a specimen was obtained for culture. METHODS: The case notes, radiological results and laboratory records of all 163 patients in our institution who underwent a neurosurgical more...
International Classification:
Hospital infection - in a neurosurgical unit
Categories:
bacterial infections of the central nervous system
Geography:
Republic of Ireland
Clin Microbiol Infect,
Vol: 9 Page: 803-9 August 2003
M. Roche; H. Humphreys; E. Smyth; J. Phillips; R. Cunney; E. McNamara; D. O'Brien; O. McArdle
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The aim of this study was to examine the absence of Epstein-Barr virus encoded RNA and latent membrane protein (LMP1) in salivary gland neoplasms
Abstract:
A series of 55 (42 benign and 13 malignant) salivary gland tumours were investigated by immunohistochemistry, to detect Epstein-Barr virus (EBV) latent membrane protein (LMP1) and by in situ hybridization for EBV-encoded RNA. Non-neoplastic gland from all the patients with tumours and 15 control glands were also examined. All cases, both neoplastic and non-neoplastic were negative for more...
International Classification:
International committee on Taxonomy of Viruses - Epstein-Barr virus
Categories:
Epstein-Barr virus; -salivary gland neoplasms
Geography:
Republic of Ireland
J Laryngol Otol,
Vol: 113 Page: 906-8 October 1999
A. M. Pollock; M. Toner; M. McMenamin; J. Walker; C. I. Timon
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This article describes the difficulties frequently encountered in managing glycaemic control in the transition periods from childhood through adolescence to adulthood, with a description of four cases illustrating these points
Abstract:
The transition from childhood through adolescence to adulthood is a difficult stage, particularly for patients with type 1 diabetes. The yearning for autonomy and independence, as well as the hormonal changes around the time of puberty, can manifest in poor glycaemic control. The focus on diet and weight increases the prevalence of eating disorders, compounding the difficulties in more...
International Classification:
Endocrine, nutritional and metabolic diseases-Report
Categories:
type 1 diabetes; glycaemic control
Geography:
Northern Ireland
Diabetes Metab Res Rev,
Vol: 17 Page: 67-74 2001 Jan-Feb
E. M. McConnell; R. Harper; M. Campbell; J. K. Nelson
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The aim of this study was to examine rates of acute gastroenteritis in Northern Ireland and the Republic of Ireland
Abstract:
Most people with acute gastroenteritis do not seek medical care and are therefore not captured by routine surveillance. For this reason, population-based studies are needed to measure the burden of illness. A study of acute gastroenteritis in Northern Ireland and the Republic of Ireland surveyed 9,903 people by telephone over the 12-month period from December 2000 to November 2001. The more...
International Classification:
Diseases of the digestive system - acute gastroenteritis
Categories:
acute gastroenteritis
Geography:
Northern Ireland and the Republic of Ireland
Commun Dis Public Health,
Vol: 7 Page: 61-7 March 2004
E. Scallan; M. Fitzgerald; C. Collins; D. Crowley; L. Daly; M. Devine; D. Igoe; T. Quigley; T. Robinson; B. Smyth
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This study described the effect of early administration of analgesia for acute abdominal pain in the accident and emergency setting
Abstract:
BACKGROUND: Recent trials suggest that the early administration of analgesia in patients with acute abdominal pain facilitates examination and does not delay diagnosis. We investigated current practice regarding analgesia for these patients. METHODS: All patients admitted via the accident and emergency department with abdominal pain were included. The main outcome measures evaluated more...
International Classification:
Drugs - analgesia
Categories:
abdominal pain
Geography:
Republic of Ireland
Eur J Emerg Med,
Vol: 11 Page: 309-12 December 2004
J. Shabbir; P. F. Ridgway; K. Lynch; C. E. Law; D. Evoy; J. B. O'Mahony; K. Mealy
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The aim of the study was to examine the topographic, radiographic and clinical data, in girls with adolescent idiopathic scoliosis, comparisons were made with theoretically perfect symmetry
Abstract:
In order to explore the concept that scoliosis is fundamentally a loss of left-right symmetry. surface topography was used to measure asymmetry in three dimensions at three levels on the back surface. Statistical analysis of prospectively collected topographic, radiographic and clinical data, in girls with adolescent idiopathic scoliosis, was carried out and comparisons were made with more...
International Classification:
Diseases of the musculoskeletal system and connective tissue - Dorsopathies - Scoliosis
Categories:
scoliosis (idiopathic)
Geography:
Republic of Ireland
Stud Health Technol Inform,
Vol: 123 Page: 109-16 2006
C. J. Goldberg; D. P. Moore; E. E. Fogarty; F. E. Dowling
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The aim of this study was to examine matrilineal risk in families with neural tube defects by comparing adverse pregnancy outcomes among maternal and paternal first cousin pregnancies.
Abstract:
Adverse pregnancy outcomes may be more frequent among sibs of individuals with neural tube defects (NTDs), and transmission of risk in families with an NTD may be more frequent among maternal relatives. In a study designed to evaluate matrilineal risk for NTDs, we compared adverse pregnancy outcomes among maternal and paternal first cousin pregnancies. Pregnancy histories were obtained more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - neural tube defects - condiction
Categories:
neural tube defects
Geography:
Republic of Ireland
Am J Med Genet A,
Vol: 140 Page: 52-61 January 2006
J. Byrne; S. Carolan
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The aim of this study was to describe the age and sex profile of patients having cataract surgery by 2 consulting ophthalmic surgeons over an 18-year period
Abstract:
PURPOSE: To investigate the age and sex profile of patients having cataract surgery by 2 consulting ophthalmic surgeons over an 18-year period. SETTING: Waterford Regional Hospital, Waterford, Republic of Ireland. METHODS: Operating theater logbooks were reviewed, and all patients having cataract surgery between January 1986 and December 2003 in Waterford Regional Hospital were more...
International Classification:
Procedure - cataract surgery
Categories:
cataract surgery
Geography:
Republic of Ireland
J Cataract Refract Surg,
Vol: 31 Page: 2162-6 November 2005
P. O'Reilly; U. Mahmoud; P. Hayes; P. Tormey; S. Beatty
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The aim of this study was to examine the age at death of people with an intellectual disability in Ireland.
Abstract:
This study examined the age at death of people with an intellectual disability in Ireland. Using data from the National Intellectual Disability Database, the average age at death of 1120 people who died between 1996 and 2001 was 45.68 years, with no difference in lifespan between men and women. A more severe level of intellectual disability predicted shorter lifespan. In general, those more...
International Classification:
Mental and behavioural disorders - Mental retardation - intellectual disabilities
Categories:
intellectual disabilities
Geography:
Republic of Ireland
J Intellect Disabil,
Vol: 10 Page: 155-64 June 2006
K. E. Lavin; B. E. McGuire; M. J. Hogan
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This case report discusses the first case of intrapartum management of prenatal airway obstruction attempted in Ireland
Abstract:
BACKGROUND Prenatal ultrasonography predicting airway obstruction can facilitate intrapartum management, revolutionising the approach to potential airway difficulties at birth. AIMS: This report presents the first case of this procedure attempted in Ireland. RESULT AND CONCLUSION: This case was unsuccessful in securing an airway, but the potential for intubation or tracheostomy with an more...
International Classification:
Certain conditions originating in the perinatal period - Report
Categories:
intrapartum management of prenatal airway obstruction
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 171 Page: 40-1 2002 Jan-Mar
T. Mackle; C. Barry-Kinsella; J. Russell
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The aim of this study was to examine renal replacement therapy in the United Kingdom with regard to prevalence and a range of demographic characteristics
Abstract:
Summary data are provided for the whole United Kingdom. There were 41,776 adult patients alive on renal replacement therapy (RRT) in the UK at the end of 2005, a prevalence for adults of 694 pmp. Addition of 748 children under the age of 18 on RRT gives a total prevalence of 706 pmp. The more detailed analysis includes data on 37,534 patients from 65 of the 70 units which returned more...
International Classification:
Health service provision
Categories:
renal replacement therapy
Geography:
the United Kingdom
Nephrol Dial Transplant,
Vol: 22 Suppl 7 Page: vii30-50 August 2007
K. Farrington; R. Rao; R. Stenkamp; D. Ansell; T. Feest
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The aim of this study was to audit all patients presenting to our Accident and Emergency Departments with All-terrain vehicles-related trauma over a 1-year period
Abstract:
All-terrain vehicles (ATVs) are fast, powerful machines that pose a significant threat to public safety. In the USA, ATVs are responsible for 273 deaths and over 68,000 injuries each year. As the incidence of ATV-related accidents in Britain and Ireland is unknown we carried out a prospective audit of all patients presenting to our Accident and Emergency Departments with ATV-related more...
International Classification:
External causes of morbidity and mortality - Accidents - characteristics-all-terrain vehicles-related trauma
Categories:
all-terrain vehicles-related trauma
Geography:
Republic of Ireland
Injury,
Vol: 34 Page: 203-5 March 2003
P. Moroney; M. Doyle; K. Mealy
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The aim of the study was to assess the utility of alpha glutathione S-transferase (alphaGST) as a potential marker of intestinal ischemia-reperfusion injury in children after cardiac surgery
Abstract:
BACKGROUND: The aim of the study was to assess the utility of alpha glutathione S-transferase (alphaGST) as a potential marker of intestinal ischemia-reperfusion injury in children after cardiac surgery. METHODS: Twenty-six patients undergoing cardiac surgery were enrolled in this longitudinal experimental study. Blood samples were drawn for analysis at specified time points during more...
International Classification:
Diseases of the digestive system - Other diseases of intestines - intestinal ischemia-reperfusion injury
Categories:
intestinal ischemia-reperfusion injur
Geography:
Republic of Ireland
J Pediatr Surg,
Vol: 41 Page: 1526-31 September 2006
M. P. McMonagle; M. Halpenny; A. McCarthy; A. Mortell; F. Manning; C. Kilty; D. Mannion; A. E. Wood; M. T. Corbally
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The aim of this study was to examine gene expression in a highly purified isolate of enterocytes taken from patients with active coeliac disease
Abstract:
BACKGROUND: Coeliac disease is a multifactorial inflammatory disorder of the intestine caused by ingestion of gluten in genetically susceptible individuals. Genes within the HLA-DQ locus are considered to contribute some 40% of the genetic influence on this disease. However, information on other disease causing genes is sparse. Since enterocytes are considered to play a central role in more...
International Classification:
Diseases of the digestive system - Other diseases of the digestive system - coeliac disease
Categories:
coeliac disease
Geography:
Republic of Ireland
BMC Genomics,
Vol: 9 Page: 377 2008
S. Bracken; G. Byrne; J. Kelly; J. Jackson; C. Feighery
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The aim of this study was to measure the effect of bed-sharing during the last sleep period on risk factors for sudden infant death syndrome
Abstract:
BACKGROUND: It is unclear if it is safe for babies to bed share with adults. In Ireland 49% of sudden infant death syndrome (SIDS) cases occur when the infant is bed-sharing with an adult. OBJECTIVE: To evaluate the effect of bed-sharing during the last sleep period on risk factors for SIDS in Irish infants. DESIGN: An 8 year (1994-2001) population based case control study of 287 SIDS more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
bed-sharing; sudden infant death syndrome
Geography:
Republic of Ireland
Arch Dis Child,
Vol: 91 Page: 318-23 April 2006
C. McGarvey; M. McDonnell; K. Hamilton; M. O'Regan; T. Matthews
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The aim of this study was to assess patient satisfaction at two out-of-hours cooperatives in Northern Ireland
Abstract:
BACKGROUND: The reorganized out-of-hours general practitioner (GP) service, resulting in the creation of out-of-hours cooperatives has been widely welcomed by the medical profession. However, GP satisfaction remains only one aspect of this reorganized service and patients' views and levels of satisfaction must have a contribution to make to the organization and delivery of the service. more...
International Classification:
Health service provision
Categories:
patient satisfaction
Geography:
Northern Ireland
J Eval Clin Pract,
Vol: 10 Page: 467-74 August 2004
K. Thompson; K. Parahoo; B. Farrell
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This study investigates a very sensitive non-contact biomotion sensor to measure actimetry and compare its performance to wrist-actimetry
Abstract:
Actimetry is a widely accepted technology for the diagnosis and monitoring of sleep disorders such as insomnia, circadian sleep/wake disturbance, and periodic leg movement. In this study we investigate a very sensitive non-contact biomotion sensor to measure actimetry and compare its performance to wrist-actimetry. A data corpus consisting of twenty subjects (ten normals, ten with sleep more...
International Classification:
Diagnostic tool (biomotion sensor) - wrist-actimetry
Categories:
non-contact biomotion sensor; actimetry (gross motor function); wrist-actimetry
Geography:
International
Conf Proc IEEE Eng Med Biol Soc,
Vol: 2007 Page: 2664-8 2007
N. A. Fox; C. Heneghan; M. Gonzalez; R. B. Shouldice; P. de Chazal
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The aim of this study was to examine positive behaviour supports for five people - with intellectual disability - in community settings
Abstract:
This study employs a multiple baseline across individual design to describe positive behaviour support for five people in community settings. The individuals represent all people with intellectual disability residing in one county with long-standing challenging behaviour resulting in serious physical injury. Five types of outcome are presented: rates of behaviour, rates of medication, more...
International Classification:
Mental and behavioural disorders - Mental retardation - intellectual disabilities
Categories:
positive behaviour support; intellectual disability
Geography:
Republic of Ireland
J Intellect Disabil,
Vol: 11 Page: 281-301 September 2007
B. McClean; I. M. Grey; M. McCracken
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This study sought to identify adults and children as under- (UR), acceptable (AR), or over-reporters (OR) of energy intake (EI) using energy expenditure measured by doubly labelled water
Abstract:
OBJECTIVE: To identify adults and children as under- (UR), acceptable (AR), or over-reporters (OR) of energy intake (EI) using energy expenditure measured by doubly labelled water (DLW) (EE(DLW)), and to use this as a reference to determine the sensitivity and specificity of (i) EE measured by heart rate (EE(HR)), and (ii) the Goldberg cut-off technique for classifying subjects into the more...
International Classification:
Diagnostic tool laboratory (doubly labelled water) - energy intake and expenditure
Categories:
energy intake; using energy expenditure; doubly labelled water
Geography:
Northern Ireland
Eur J Clin Nutr,
Vol: 57 Page: 455-63 March 2003
M. B. Livingstone; P. J. Robson; A. E. Black; W. A. Coward; J. M. Wallace; M. C. McKinley; J. J. Strain; P. G. McKenna
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This study aimed to explore teachers' knowledge of the signs and symptoms of psychiatric disorder
Abstract:
Research has shown that children and young people with intellectual disabilities are at a greater risk of developing a psychiatric disorder than their non-disabled peers. However, no information exists regarding teachers' knowledge of the signs and symptoms of these conditions. Using a postal questionnaire, 36 teachers working within schools for children and young people with severe more...
International Classification:
Practice/knowledge - psychiatric disorder
Categories:
psychiatric disorder
Geography:
Northern Ireland
J Intellect Disabil,
Vol: 11 Page: 183-95 June 2007
L. Taggart; P. McMullan
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This case report discusses a classically affected neonate with de Lange syndrome, an affected mother and probably affected maternal grandmother
Abstract:
The existence of familial de Lange syndrome has been documented in sibs and in parent-child families, but the inheritance pattern continues to be the cause of much debate. We describe a classically affected neonate with de Lange syndrome, an affected mother and probably affected maternal grandmother. These cases show evidence for a dominantly inherited syndrome with a de Lange phenotype. more...
International Classification:
Syndrome
Categories:
de Lange syndrome
Geography:
Northern Ireland
Clin Dysmorphol,
Vol: 12 Page: 241-4 October 2003
V. McConnell; T. Brown; P. J. Morrison
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The aim of the study was to conduct an open-label prospective study assessing the efficacy of activated protein C replacement therapy in patients with severe meningococcal septicemia, purpura fulminans, and multiorgan failure
Abstract:
Activated protein C (APC) is a natural anticoagulant that plays a pivotal role in coagulation homeostasis. Severe inherited or acquired deficiency results in a clinical syndrome called purpura fulminans. In addition, APC also appears to have potent cytokine-modifying properties and is protective in animal models of sepsis. The dual functional properties of APC are particularly relevant more...
International Classification:
Certain infectious and parasitic diseases - Other bacterial diseases - meningococcal disease
Categories:
severe meningococcal septicemia
Geography:
Republic of Ireland
Blood,
Vol: 96 Page: 3719-24 December 2000
B. White; W. Livingstone; C. Murphy; A. Hodgson; M. Rafferty; O. P. Smith
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The aim of this study was to analysis the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk
Abstract:
BACKGROUND: Polymorphisms in the serine protease inhibitor gene serine peptidase inhibitor Kazal type 5 (SPINK5) and the serine protease kallikrein-related peptidase 7 gene (KLK7) appear to confer risk to eczema in some cohorts, but these findings have not been widely replicated. These genes encode proteins thought to be involved in the regulation of posttranslation processing of more...
International Classification:
Diseases of the skin and subcutaneous tissue - Dermatitis and eczema - eczema
Categories:
range of polymorphisms; -eczema risk
Geography:
International
J Allergy Clin Immunol,
Vol: 122 Page: 560-8 e4 September 2008
S. Weidinger; H. Baurecht; S. Wagenpfeil; J. Henderson; N. Novak; A. Sandilands; H. Chen; E. Rodriguez; G. M. O'Regan; R. Watson; H. Liao; Y. Zhao; J. N. Barker; M. Allen; N. Reynolds; S. Meggitt; K. Northstone; G. D. Smith; C. Strobl; C. Stahl; T. Kneib; N. Klopp; T. Bieber; H. Behrendt; C. N. Palmer; H. E. Wichmann; J. Ring; T. Illig; W. H. McLean; A. D. Irvine
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