Irish Child Health Database - Peer Reviewed Papers
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Middle Aged
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The aim of this study was to audit the incidence, type of injury, medical consequences and outcome of patients with stab or gunshot wounds presenting to the Mid-Western Regional Hospital, Limerick,
Abstract:
BACKGROUND: According to a recent study in Cardiff, the incidence of stab wounds is 14 per 100,000 population per annum. No such figures are available for Ireland. AIM: To evaluate the incidence, type of injury, medical consequences and outcome of patients with stab or gunshot wounds presenting to the Mid-Western Regional Hospital, Limerick, over a 12 month period. METHOD: A more...
International Classification:
External causes of morbidity and mortality treatment - Accidents - stab or gunshot wounds
Categories:
stab or gunshot wounds
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 173 Page: 102-4 2004 Apr-Jun
J. Shabbir; C. O. McDonnell; J. B. O'Sullivan; K. Cahill; A. Moore; R. Raminlagan; G. Quinn; P. A. Grace
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This study examined patients with phaeochromocytoma
Abstract:
Thirty three patients with phaeochromocytomas had surgery in St. Vincent's Hospital between 1950 and 1997. 32 patients had hypertension, 32 had palpitations and 30 had excessive sweating. All patients had at least one of these cardinal symptoms. Diagnostic tests changed over this period. In the early cases the phentolamine test was used, later diagnosis was confirmed by measurement of more...
International Classification:
Neoplasms - Malignant neoplasms - phaeochromocytoma
Categories:
phaeochromocytoma
Geography:
Republic of Ireland
Ir Med J,
Vol: 94 Page: 200-3 2001 Jul-Aug
T. O'Halloran; G. McGreal; E. McDermott; N. O'Higgins
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The aim of this study was to audit the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome
Abstract:
The objective of the investigation was to determine the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome. A prospective audit of patients with complex hydrocephalus undergoing Hakim programmable valve implantation between 1989 and 1994 in the United Kingdom and Ireland, was followed-up for a minimum of 5 more...
International Classification:
Procedure - Hakim valve implants
Categories:
Hakim valve implants
Geography:
Republic of Ireland and the United Kingdom
Br J Neurosurg,
Vol: 14 Page: 535-42 December 2000
A. D. Kay; A. J. Fisher; C. O'Kane; H. K. Richards; J. D. Pickard
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The aim of this study was to examine the linguistic anthropology which underpins the language dynamics of two Gaeltacht (Irish-speaking) areas
Abstract:
This paper presents an analysis of the linguistic anthropology which underpins the language dynamics of two Gaeltacht (Irish-speaking) areas, Ros Muc in Conamara, Co. Galway and Rath Cairn in Co. Meath. This research highlights what could be considered a socio-linguistic paradox: the community (Rath Cairn) which engages more vigorously in language maintenance endeavors, and exhibits a more...
International Classification:
Anthropology or ethnographic-language
Categories:
linguistic anthropology; language dynamics
Geography:
Republic of Ireland
Coll Antropol,
Vol: 28 Suppl 1 Page: 73-81 2004
C. O. Giollagain
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In this study a retrospective analysis of all consecutive helicopter transfers to the Beaumont neurosurgical unit was performed over a two year period from January 1994 to December 1996.
Abstract:
A retrospective analysis of all consecutive helicopter transfers to the Beaumont neurosurgical unit was performed over a two year period from January 1994 to December 1996. There were 55 transfers, 55% of which were for trauma patients. Sixty two per cent were intubated prior to transfer. The mean length of stay at the referring hospital prior to transfer was 12.25 hours (range 3-98 more...
International Classification:
Economic- Health service provision-transport
Categories:
helicopter transfers
Geography:
Republic of Ireland
Ir Med J,
Vol: 93 Page: 50-1 2000 Mar-Apr
R. Dardis; G. Roberts; J. Phillips
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The aim of this study was to examine a genome-wide linkage scan using 4710 single-nucleotide polymorphisms in families with more then one member with Vesicoureteric reflux
Abstract:
BACKGROUND: Vesicoureteric reflux (VUR) is the retrograde flow of urine from the bladder into the ureters. It is the most common urological anomaly in children, and a major cause of end-stage renal failure and hypertension in both children and adults. VUR is seen in approximately 1-2% of Caucasian newborns and is frequently familial. Objective and METHODS: In order to search for genetic more...
International Classification:
Other - genome-wide linkage scan
Categories:
genome-wide linkage scan
Geography:
Republic of Ireland
J Med Genet,
Vol: 44 Page: 710-7 November 2007
H. Kelly; C. M. Molony; J. M. Darlow; M. E. Pirker; A. Yoneda; A. J. Green; P. Puri; D. E. Barton
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The aim of this study was to examine the frequency of a false negative result by sequencing studies in patients with hereditary pancreatitis and in healthy controls
Abstract:
BACKGROUND AND AIMS: Hereditary pancreatitis (HP) is a rare form of recurrent acute and chronic pancreatitis. Mutations in the cationic trypsinogen (protease serine 1, PRSS1) gene have been identified as causing HP. The R122H (previously known as R117H) mutation is the commonest and can be detected by a single and rapid polymerase chain reaction/restriction fragment length polymorphism more...
International Classification:
Diseases of the digestive system - Disorders of gallbladder, biliary tract and pancreas - hereditary pancreatitis
Categories:
hereditary pancreatitis;
Geography:
the United Kingdom
Gut,
Vol: 48 Page: 247-50 February 2001
N. Howes; W. Greenhalf; S. Rutherford; M. O'Donnell; R. Mountford; I. Ellis; D. Whitcomb; C. Imrie; B. Drumm; J. P. Neoptolemos
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The aim of this study was to assess the health economics of realtime teledermatology compared with conventional care: an urban versus rural perspective
Abstract:
A randomized controlled trial was carried out to measure the cost-effectiveness of realtime teledermatology compared with conventional outpatient dermatology care for patients from urban and rural areas. One urban and one rural health centre were linked to a regional hospital in Northern Ireland by ISDN at 128 kbit/s. Over two years, 274 patients required a hospital outpatient more...
International Classification:
Evaluation of the effectiveness of teledermatology v. conventional assessment
Categories:
teledermatology v. conventional care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 7 Page: 108-18 2001
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; C. Evans; N. Hicks; P. Jacklin; H. E. Lotery; C. Mathews; J. Paisley; P. Reid; K. Steele; R. Wootton
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The aim of this study was to assess realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial
Abstract:
The clinical effectiveness of realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial. A total of 204 patients took part--102 patients were randomized to the realtime teledermatology consultation, 96 of whose cases were also referred using a store-and-forward technique, and 102 to the more...
International Classification:
Evaluation of the effectiveness of two treatments - in dermatological care
Categories:
dermatological care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 6 Suppl 1 Page: S1-3 2000
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; N. Hicks; H. E. Lotery; C. Mathews; J. Paisley; K. Steele; R. Wootton
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The aim of this study was to examine the number of factors associated with the occurrence of suicide
Abstract:
This study reports on 60 cases of suicide in Londonderry, Northern Ireland from January 2000 to December 2005. The research focused on a number of factors associated with the occurrence of suicide. These included age, gender, employment status, method used and possible predisposing factors. Additionally, the seasonality of occurrence was also investigated. Notably, over the period of more...
International Classification:
External causes of morbidity and mortality - Intentional self-harm - suicide
Categories:
suicide
Geography:
Northern Ireland
J Forensic Leg Med,
Vol: 15 Page: 148-57 April 2008
A. Burns; E. Goodall; T. Moore
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The aim of this study was to benchmark the psychological state and physical rehabilitation of patients who have sustained limb loss as a result of terrorist activity in Northern Ireland
Abstract:
OBJECTIVE: To benchmark the psychological state and physical rehabilitation of patients who have sustained limb loss as a result of terrorist activity in Northern Ireland and to determine their satisfaction with the period of primary prosthetic rehabilitation and the artificial limb. METHOD: All patients who sustained limb loss as a result of the Troubles and were referred to our more...
International Classification:
War, violence and conflict
Categories:
psychological state as a result of terrorist activity
Geography:
Northern Ireland
Disabil Rehabil,
Vol: 28 Page: 797-801 June 2006
L. Graham; R. C. Parke; M. C. Paterson; M. Stevenson
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The aim of this study was to compare Irish asylum seekers to other General Medical Scheme patients possessing Irish citizenship in terms of their utilisation of GP services, morbidity patterns and consultation outcomes
Abstract:
To compare Irish asylum seekers to other General Medical Scheme (GMS) patients possessing Irish citizenship in terms of their utilisation of GP services, morbidity patterns and consultation outcomes. A retrospective 1 year study on patient records in two Galway City practices was performed. All asylum seekers who were patients of the two practices were compared with two controls each more...
International Classification:
Health service provision
Categories:
morbidity patterns; consultation outcomes; -asylum seekers
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 461-4 May 2007
J. D. McMahon; A. Macfarlane; G. E. Avalos; P. Cantillon; A. W. Murphy
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The aim of this study was to examine the incidence, causes, associated factors, and pathological findings in people who died while exercising
Abstract:
BACKGROUND: Sudden death in sport is rare, but when it occurs the effects are devastating. There have not been any reports to date describing the frequency and causes of sudden death in sport in the Republic of Ireland. AIM: To describe the incidence, possible causes, associated factors, and pathological findings in people who died while exercising in the Republic of Ireland in the 10 more...
International Classification:
Deaths - while exercising
Categories:
death while exercising
Geography:
Republic of Ireland
Br J Sports Med,
Vol: 34 Page: 258-61 August 2000
F. Quigley
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This study aimed to review and document the changing patterns in diagnosis, causes and treatment of bacterial infections of the central nervous system in a national neurosurgical unit
Abstract:
OBJECTIVES: To review and document the changing patterns in diagnosis, causes and treatment of bacterial infections of the central nervous system (CNS) in a national neurosurgical unit only in patients from whom a specimen was obtained for culture. METHODS: The case notes, radiological results and laboratory records of all 163 patients in our institution who underwent a neurosurgical more...
International Classification:
Hospital infection - in a neurosurgical unit
Categories:
bacterial infections of the central nervous system
Geography:
Republic of Ireland
Clin Microbiol Infect,
Vol: 9 Page: 803-9 August 2003
M. Roche; H. Humphreys; E. Smyth; J. Phillips; R. Cunney; E. McNamara; D. O'Brien; O. McArdle
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The aim of this study was to examine the absence of Epstein-Barr virus encoded RNA and latent membrane protein (LMP1) in salivary gland neoplasms
Abstract:
A series of 55 (42 benign and 13 malignant) salivary gland tumours were investigated by immunohistochemistry, to detect Epstein-Barr virus (EBV) latent membrane protein (LMP1) and by in situ hybridization for EBV-encoded RNA. Non-neoplastic gland from all the patients with tumours and 15 control glands were also examined. All cases, both neoplastic and non-neoplastic were negative for more...
International Classification:
International committee on Taxonomy of Viruses - Epstein-Barr virus
Categories:
Epstein-Barr virus; -salivary gland neoplasms
Geography:
Republic of Ireland
J Laryngol Otol,
Vol: 113 Page: 906-8 October 1999
A. M. Pollock; M. Toner; M. McMenamin; J. Walker; C. I. Timon
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The aim of this study was to examine rates of acute gastroenteritis in Northern Ireland and the Republic of Ireland
Abstract:
Most people with acute gastroenteritis do not seek medical care and are therefore not captured by routine surveillance. For this reason, population-based studies are needed to measure the burden of illness. A study of acute gastroenteritis in Northern Ireland and the Republic of Ireland surveyed 9,903 people by telephone over the 12-month period from December 2000 to November 2001. The more...
International Classification:
Diseases of the digestive system - acute gastroenteritis
Categories:
acute gastroenteritis
Geography:
Northern Ireland and the Republic of Ireland
Commun Dis Public Health,
Vol: 7 Page: 61-7 March 2004
E. Scallan; M. Fitzgerald; C. Collins; D. Crowley; L. Daly; M. Devine; D. Igoe; T. Quigley; T. Robinson; B. Smyth
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This study described the effect of early administration of analgesia for acute abdominal pain in the accident and emergency setting
Abstract:
BACKGROUND: Recent trials suggest that the early administration of analgesia in patients with acute abdominal pain facilitates examination and does not delay diagnosis. We investigated current practice regarding analgesia for these patients. METHODS: All patients admitted via the accident and emergency department with abdominal pain were included. The main outcome measures evaluated more...
International Classification:
Drugs - analgesia
Categories:
abdominal pain
Geography:
Republic of Ireland
Eur J Emerg Med,
Vol: 11 Page: 309-12 December 2004
J. Shabbir; P. F. Ridgway; K. Lynch; C. E. Law; D. Evoy; J. B. O'Mahony; K. Mealy
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The aim of this study was to examine matrilineal risk in families with neural tube defects by comparing adverse pregnancy outcomes among maternal and paternal first cousin pregnancies.
Abstract:
Adverse pregnancy outcomes may be more frequent among sibs of individuals with neural tube defects (NTDs), and transmission of risk in families with an NTD may be more frequent among maternal relatives. In a study designed to evaluate matrilineal risk for NTDs, we compared adverse pregnancy outcomes among maternal and paternal first cousin pregnancies. Pregnancy histories were obtained more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - neural tube defects - condiction
Categories:
neural tube defects
Geography:
Republic of Ireland
Am J Med Genet A,
Vol: 140 Page: 52-61 January 2006
J. Byrne; S. Carolan
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The aim of this study was to describe the age and sex profile of patients having cataract surgery by 2 consulting ophthalmic surgeons over an 18-year period
Abstract:
PURPOSE: To investigate the age and sex profile of patients having cataract surgery by 2 consulting ophthalmic surgeons over an 18-year period. SETTING: Waterford Regional Hospital, Waterford, Republic of Ireland. METHODS: Operating theater logbooks were reviewed, and all patients having cataract surgery between January 1986 and December 2003 in Waterford Regional Hospital were more...
International Classification:
Procedure - cataract surgery
Categories:
cataract surgery
Geography:
Republic of Ireland
J Cataract Refract Surg,
Vol: 31 Page: 2162-6 November 2005
P. O'Reilly; U. Mahmoud; P. Hayes; P. Tormey; S. Beatty
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The aim of this study was to examine the age at death of people with an intellectual disability in Ireland.
Abstract:
This study examined the age at death of people with an intellectual disability in Ireland. Using data from the National Intellectual Disability Database, the average age at death of 1120 people who died between 1996 and 2001 was 45.68 years, with no difference in lifespan between men and women. A more severe level of intellectual disability predicted shorter lifespan. In general, those more...
International Classification:
Mental and behavioural disorders - Mental retardation - intellectual disabilities
Categories:
intellectual disabilities
Geography:
Republic of Ireland
J Intellect Disabil,
Vol: 10 Page: 155-64 June 2006
K. E. Lavin; B. E. McGuire; M. J. Hogan
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The aim of this study was to examine renal replacement therapy in the United Kingdom with regard to prevalence and a range of demographic characteristics
Abstract:
Summary data are provided for the whole United Kingdom. There were 41,776 adult patients alive on renal replacement therapy (RRT) in the UK at the end of 2005, a prevalence for adults of 694 pmp. Addition of 748 children under the age of 18 on RRT gives a total prevalence of 706 pmp. The more detailed analysis includes data on 37,534 patients from 65 of the 70 units which returned more...
International Classification:
Health service provision
Categories:
renal replacement therapy
Geography:
the United Kingdom
Nephrol Dial Transplant,
Vol: 22 Suppl 7 Page: vii30-50 August 2007
K. Farrington; R. Rao; R. Stenkamp; D. Ansell; T. Feest
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The aim of this study was to examine gene expression in a highly purified isolate of enterocytes taken from patients with active coeliac disease
Abstract:
BACKGROUND: Coeliac disease is a multifactorial inflammatory disorder of the intestine caused by ingestion of gluten in genetically susceptible individuals. Genes within the HLA-DQ locus are considered to contribute some 40% of the genetic influence on this disease. However, information on other disease causing genes is sparse. Since enterocytes are considered to play a central role in more...
International Classification:
Diseases of the digestive system - Other diseases of the digestive system - coeliac disease
Categories:
coeliac disease
Geography:
Republic of Ireland
BMC Genomics,
Vol: 9 Page: 377 2008
S. Bracken; G. Byrne; J. Kelly; J. Jackson; C. Feighery
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The aim of this study was to assess patient satisfaction at two out-of-hours cooperatives in Northern Ireland
Abstract:
BACKGROUND: The reorganized out-of-hours general practitioner (GP) service, resulting in the creation of out-of-hours cooperatives has been widely welcomed by the medical profession. However, GP satisfaction remains only one aspect of this reorganized service and patients' views and levels of satisfaction must have a contribution to make to the organization and delivery of the service. more...
International Classification:
Health service provision
Categories:
patient satisfaction
Geography:
Northern Ireland
J Eval Clin Pract,
Vol: 10 Page: 467-74 August 2004
K. Thompson; K. Parahoo; B. Farrell
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This study investigates a very sensitive non-contact biomotion sensor to measure actimetry and compare its performance to wrist-actimetry
Abstract:
Actimetry is a widely accepted technology for the diagnosis and monitoring of sleep disorders such as insomnia, circadian sleep/wake disturbance, and periodic leg movement. In this study we investigate a very sensitive non-contact biomotion sensor to measure actimetry and compare its performance to wrist-actimetry. A data corpus consisting of twenty subjects (ten normals, ten with sleep more...
International Classification:
Diagnostic tool (biomotion sensor) - wrist-actimetry
Categories:
non-contact biomotion sensor; actimetry (gross motor function); wrist-actimetry
Geography:
International
Conf Proc IEEE Eng Med Biol Soc,
Vol: 2007 Page: 2664-8 2007
N. A. Fox; C. Heneghan; M. Gonzalez; R. B. Shouldice; P. de Chazal
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This study aimed to explore teachers' knowledge of the signs and symptoms of psychiatric disorder
Abstract:
Research has shown that children and young people with intellectual disabilities are at a greater risk of developing a psychiatric disorder than their non-disabled peers. However, no information exists regarding teachers' knowledge of the signs and symptoms of these conditions. Using a postal questionnaire, 36 teachers working within schools for children and young people with severe more...
International Classification:
Practice/knowledge - psychiatric disorder
Categories:
psychiatric disorder
Geography:
Northern Ireland
J Intellect Disabil,
Vol: 11 Page: 183-95 June 2007
L. Taggart; P. McMullan
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The aim of the study was to conduct an open-label prospective study assessing the efficacy of activated protein C replacement therapy in patients with severe meningococcal septicemia, purpura fulminans, and multiorgan failure
Abstract:
Activated protein C (APC) is a natural anticoagulant that plays a pivotal role in coagulation homeostasis. Severe inherited or acquired deficiency results in a clinical syndrome called purpura fulminans. In addition, APC also appears to have potent cytokine-modifying properties and is protective in animal models of sepsis. The dual functional properties of APC are particularly relevant more...
International Classification:
Certain infectious and parasitic diseases - Other bacterial diseases - meningococcal disease
Categories:
severe meningococcal septicemia
Geography:
Republic of Ireland
Blood,
Vol: 96 Page: 3719-24 December 2000
B. White; W. Livingstone; C. Murphy; A. Hodgson; M. Rafferty; O. P. Smith
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The aim of this study was to analysis the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk
Abstract:
BACKGROUND: Polymorphisms in the serine protease inhibitor gene serine peptidase inhibitor Kazal type 5 (SPINK5) and the serine protease kallikrein-related peptidase 7 gene (KLK7) appear to confer risk to eczema in some cohorts, but these findings have not been widely replicated. These genes encode proteins thought to be involved in the regulation of posttranslation processing of more...
International Classification:
Diseases of the skin and subcutaneous tissue - Dermatitis and eczema - eczema
Categories:
range of polymorphisms; -eczema risk
Geography:
International
J Allergy Clin Immunol,
Vol: 122 Page: 560-8 e4 September 2008
S. Weidinger; H. Baurecht; S. Wagenpfeil; J. Henderson; N. Novak; A. Sandilands; H. Chen; E. Rodriguez; G. M. O'Regan; R. Watson; H. Liao; Y. Zhao; J. N. Barker; M. Allen; N. Reynolds; S. Meggitt; K. Northstone; G. D. Smith; C. Strobl; C. Stahl; T. Kneib; N. Klopp; T. Bieber; H. Behrendt; C. N. Palmer; H. E. Wichmann; J. Ring; T. Illig; W. H. McLean; A. D. Irvine
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The aim of this study was to examine the ACE I/D genotype pattern in familial vesicoureteric reflux patients
Abstract:
Vesicoureteric reflux (VUR) is known to occur in families. In siblings of index patients with VUR, there is a much higher incidence (16% to 46%) than in the general population. The renin-angiotensin system plays an important role in renal development. Recently, it has been reported that angiotensin-converting enzyme (ACE) I/D gene polymorphism is a risk factor for renal parenchymal more...
International Classification:
Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux
Categories:
vesicoureteric reflux
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 17 Page: 308-11 May 2001
A. Yoneda; T. Oue; P. Puri
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This study examined pitfalls in the acute management of ankle fractures which were referred to a regional orthopaedic unit
Abstract:
OBJECTIVE: The aim of this study was to identify pitfalls in the acute management of ankle fractures which were referred to a regional orthopaedic unit. This unit provides orthopaedic services for the catchment area of the Waterford Emergency Department together with three additional emergency units in the south-eastern region of Ireland. METHODS: This is a retrospective study of all more...
International Classification:
Injury, poisoning and certain other consequences of external causes - fractures
Categories:
ankle fractures
Geography:
Republic of Ireland
Eur J Emerg Med,
Vol: 12 Page: 216-9 October 2005
C. Deasy; D. Murphy; G. C. McMahon; I. P. Kelly
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The aim of this study was to describe feedback on the likelihood of bacterial infection and measured the impact on initial patient expectation for antibiotic therapy
Abstract:
Antibiotics are overused in the management of sore throat. Using a scoring system with 108 attenders, we provided feedback on the likelihood of bacterial infection and measured the impact on initial patient expectation for antibiotic therapy. Patient attitudes and beliefs regarding antibiotics were also examined. Of sixty two patients whose score suggested viral infection, 18(29%) opted more...
International Classification:
Health service provision
Categories:
expectation for antibiotic therapy
Geography:
Northern Ireland
Ir Med J,
Vol: 93 Page: 211-2 October 2000
J. Macnamara; P. Harrington; M. Walsh; M. Walsh; M. Burke; N. Walsh
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The aim of this study was to evaluate the use, timing and appropriateness of antimicrobial prophylaxis perioperatively, in otorhinolaryngological/head and neck
procedures.
Abstract:
Prophylactic antimicrobial therapy is defined as the administration of an antimicrobial agent prior to contamination of previously sterile tissues or fluids, in an attempt to reduce the microbial burden of intraoperative contamination. Prophylactic antimicrobial therapy should cover the anticipated floral contamination, with therapeutic levels from incision to closure. There is level I more...
International Classification:
Procedure - otorhinolaryngological
Categories:
otorhinolaryngological
Geography:
Republic of Ireland
Clin Otolaryngol,
Vol: 32 Page: 204-7 June 2007
B. G. Fennessy; M. Harney; M. J. O'Sullivan; C. Timon
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The aim of this study was to measure antimicrobial susceptibility of invasive isolates of Streptococcus pneumoniae in Ireland
Abstract:
Between January 1999 and June 2002, 646 invasive isolates of Streptococcus pneumoniae were collected in Ireland. MICs of penicillin, ciprofloxacin, cefotaxime, moxifloxacin and linezolid were determined by Etest methodology. Eighty-seven (13.5%) isolates showed intermediate resistance to penicillin, while seven (1.1%) showed high-level resistance. Eighty-seven (13.5%) isolates were more...
International Classification:
Bacterium - Streptococcus pneumoniae
Categories:
antimicrobial susceptibility; Streptococcus pneumoniae
Geography:
International
Clin Microbiol Infect,
Vol: 10 Page: 657-9 July 2004
P. Clarke; S. Murchan; E. G. Smyth; H. Humphreys
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The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors
Abstract:
OBJECTIVE: The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors using multiple logistic regression analysis. METHODS: A total of 1328 isolates of Streptococcus pneumoniae, 1894 Haemophilus influenzae and 845 Moraxella more...
International Classification:
Diseases of the respiratory system - lower respiratory pathogens
Categories:
lower respiratory pathogens
Geography:
Republic of Ireland and the United Kingdom
J Antimicrob Chemother,
Vol: 52 Page: 931-43 December 2003
R. Reynolds; J. Shackcloth; D. Felmingham; A. MacGowan
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The aim of this study was to examine the association between antiretroviral therapy in pregnancy and premature delivery, birthweight, stillbirth and neonatal mortality, in pregnancies in HIV-infected women delivering between 1990 and 2005
Abstract:
OBJECTIVE: To explore the association between antiretroviral therapy in pregnancy and premature delivery, birthweight, stillbirth and neonatal mortality, in pregnancies in HIV-infected women delivering between 1990 and 2005. DESIGN: Pregnancies in women with diagnosed HIV infection in the UK and Ireland are notified to the National Study of HIV in Pregnancy and Childhood (NSHPC) through more...
International Classification:
Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV
Categories:
antiretroviral therapy in pregnancy
Geography:
Republic of Ireland and the United Kingdom
Aids,
Vol: 21 Page: 1019-26 May 2007
C. L. Townsend; M. Cortina-Borja; C. S. Peckham; P. A. Tookey
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The aim of this study was to assess the potential use of wound wicks to reduce the rate of infection following appendectomy
Abstract:
The role of prophylactic antibiotics is well established for contaminated wounds, but the use of antiseptic wound wicks is controversial. The aim of this work was to study the potential use of wound wicks to reduce the rate of infection following appendectomy. This prospective randomized controlled clinical trial was conducted at a university hospital in the department of surgery. The more...
International Classification:
Evaluation of the effectiveness of treatments - following appendectomy
Categories:
rate of infection following appendectomy
Geography:
Republic of Ireland
World J Surg,
Vol: 26 Page: 631-4 May 2002
G. T. McGreal; A. Joy; B. Manning; J. L. Kelly; J. A. O'Donnell; W. W. Kirwan; H. P. Redmond
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This study reported use of etanercept and infliximab, novel biological agents, against tumour necrosis factor alpha (TNFalpha)
Abstract:
Etanercept and infliximab are novel biological agents targeted against tumour necrosis factor alpha (TNFalpha), a key cytokine in the pathogenesis of rheumatoid arthritis (RA). We report the results of their use over a two year period in 94 patients with severe inflammatory arthritis. Eighty-eight adults with active inflammatory arthritis (82 with RA), unresponsive to all conventional more...
International Classification:
Other - tumour necrosis factor alpha (TNFalpha)
Categories:
tumour necrosis factor alpha
Geography:
Northern Ireland
Ulster Med J,
Vol: 71 Page: 101-5 November 2002
A. P. Cairns; A. J. Taggart
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This aim of this study was to assess injury-related mortality, disability and disability-adjusted life years (DALYs) in six European countries
Abstract:
OBJECTIVE: To assess injury-related mortality, disability and disability-adjusted life years (DALYs) in six European countries. METHODS: Epidemiological data (hospital discharge registers, emergency department registers, mortality databases) were obtained for Austria, Denmark, Ireland, Netherlands, Norway, and the United Kingdom (England and Wales). For each country, the burden of more...
International Classification:
Injury, poisoning and certain other consequences of external causes - injury
Categories:
injury-related mortality; injury-related disability; disability-adjusted life years
Geography:
International
Bull World Health Organ,
Vol: 85 Page: 27-34 January 2007
S. Polinder; W. J. Meerding; S. Mulder; E. Petridou; E. van Beeck
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The aim of this study was to examine the association between the allele 2 of the interleukin 1 receptor antagonist gene
Abstract:
BACKGROUND AND AIMS: An association between the allele 2 of the interleukin 1 receptor antagonist gene variable number tandem repeats polymorphism in intron 2 and ulcerative colitis was first reported in 1994. Subsequent studies in Caucasian Northern European patients have not confirmed this, although trends towards an association were observed. The lack of statistical significance more...
International Classification:
Diseases of the digestive system - Noninfective enteritis and colitis - ulcerative colitis
Categories:
allele 2 of the interleukin 1 receptor antagonist gene variable; -ulcerative colitis
Geography:
International
Gut,
Vol: 48 Page: 461-7 April 2001
M. J. Carter; F. S. di Giovine; S. Jones; J. Mee; N. J. Camp; A. J. Lobo; G. W. Duff
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The aim of the study was to examine attachment styles and psychological profiles of child sex offenders in Ireland
Abstract:
When 29 child sex offenders, 30 violent offenders, 30 nonviolent offenders, and 30 community controls were compared, a secure adult attachment style was 4 times less common in the child sex offender group than in any of the other three groups. Ninety-three percent of sex offenders had an insecure adult attachment style. Compared with community controls, the child sex offender group more...
International Classification:
Sexual abuse - child sex offenders profiles
Categories:
attachment styles; psychological profiles
Geography:
Republic of Ireland
J Interpers Violence,
Vol: 19 Page: 228-51 February 2004
F. Marsa; G. O'Reilly; A. Carr; P. Murphy; M. O'Sullivan; A. Cotter; D. Hevey
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The aim of this study was to audit experience and outcomes of specialised clinic for the antenatal care of high-risk patients after the first year in operation
Abstract:
A specialised clinic for the antenatal care of high-risk patients was established in Cork in January 2004. It is led by 2 specialists in materno-fetal medicine and provides care for patients from a large catchment area. Small clinic numbers, specialised midwives, ready access to medical experts and fetal assessment facilities, facilitate an efficient use of resources. We report on the more...
International Classification:
Pregnancy, childbirth and the puerperium - antenatal care of high-risk patients
Categories:
antenatal care of high-risk patients
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 591-3 October 2007
C. Allen; R. Greene; J. Higgins
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The aim of this audit was to determine if a centralised retrieval system for interhospital transport of critically ill patients in Ireland by Mobile Intensive Care Ambulance Service is safe and efficient.
Abstract:
The transfer of critically ill patients between hospitals carries significant risk. The Mobile Intensive Care Ambulance Service (MICAS) in Ireland was established in 1996 to provide a ground transfer service between hospitals for critically ill patients. The aim of this audit was to determine if a centralised retrieval system for interhospital transport of critically ill patients in more...
International Classification:
Factors influencing health status and contact with health services - persons encountering health services for examination and investigation - centralised retrieval system for interhospital transport
Categories:
centralised retrieval system for interhospital transport
Geography:
Republic of Ireland
Ir Med J,
Vol: 99 Page: 76-8 March 2006
D. Rohan; R. Dwyer; J. Costello; D. Phelan
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The aim of this study was to examine the prevalence of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, the AIRE mutations involved and clinical features of this population
Abstract:
OBJECTIVE: To determine the Irish prevalence of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), the AIRE mutations involved and clinical features of this population. METHODS: All patients were identified through paediatricians and endocrinologists in Ireland. Patients were invited to attend a multidisciplinary clinic. RESULTS: Thirty-one patients (2-56 years), more...
International Classification:
Syndrome - autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Categories:
autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Geography:
Republic of Ireland
J Pediatr Endocrinol Metab,
Vol: 19 Page: 1343-52 November 2006
M. Dominguez; E. Crushell; T. Ilmarinen; E. McGovern; S. Collins; B. Chang; P. Fleming; A. D. Irvine; D. Brosnahan; I. Ulmanen; N. Murphy; C. Costigan
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The aim of this study was to characterise an Irish kindred with apparent autosomal dominant peripheral retinal lesions and peripapillary crescents associated with retinal breaks and uveitis to examine the association with altered homocysteine metabolism
Abstract:
PURPOSE: To characterise an Irish kindred with apparent autosomal dominant peripheral retinal lesions and peripapillary crescents associated with retinal breaks and uveitis and assess whether these findings were associated with altered homocysteine metabolism. METHODS: Family members were followed prospectively and regularly examined. Molecular genetic analysis was performed on family more...
International Classification:
Diseases of the eye and adnexa - Disorders of sclera, cornea, iris and ciliary body - uveitis
Categories:
peripheral retinal lesions; uveitis
Geography:
Republic of Ireland
Graefes Arch Clin Exp Ophthalmol,
Vol: 239 Page: 102-8 February 2001
M. Cahill; P. Gallagher; A. Whitehead; R. Acheson
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This article discusses background and methods for evaluating quality of life in children and adolescents with diabetes
Geography:
Republic of Ireland
Acta Biomed,
Vol: 74 Suppl 1 Page: 7-12 2003
H. M. Hoey
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The aim of this study was to describe behavioural characteristics and autistic features in individuals with Coen Syndrome
Abstract:
Diagnostic criteria for Cohen Syndrome are based largely on physical characteristics, and systematic information about behaviour and social functioning is limited. Typically, individuals with this condition are described as being very sociable and as showing low rates of pathology. However, recent studies have indicated that behavioural difficulties may occur more frequently than more...
International Classification:
Syndrome - Coen
Categories:
Coen Syndrome
Geography:
International
Eur Child Adolesc Psychiatry,
Vol: 14 Page: 57-64 March 2005
P. Howlin; J. Karpf; J. Turk
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This study examined the surgical results of the first one hundred cochlear implant operations at the Belfast Cochlear Implant Centre
Abstract:
We assess the surgical results of the first one hundred cochlear implant operations at the Belfast Cochlear Implant Centre. This paper is in the form of a retrospective case series, taking into account the surgical technique used and any problems encountered. Initially 28 operations were performed using the standard inverted U-shaped incision. After Gibson and Harrison described a more...
International Classification:
Procedure - cochlear implant
Categories:
cochlear implant operations
Geography:
Northern Ireland
Rev Laryngol Otol Rhinol (Bord),
Vol: 121 Page: 9-11 2000
S. M. Hampton; J. G. Toner
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This study analysed the elective MR scans of the lumbosacral spine with findings that Bertolotti's syndrome is a major cause of back pain in young people
Abstract:
Bertolotti's syndrome is characterised by anomalous enlargement of the transverse process(es) of the most caudal lumbar vertebra which may articulate or fuse with the sacrum or ilium and cause isolated L4/5 disc disease. We analysed the elective MR scans of the lumbosacral spine of 769 consecutive patients with low back pain taken between July 2003 and November 2004. Of these 568 showed more...
International Classification:
Syndrome - Bertolotti's
Categories:
Bertolotti's syndrome
Geography:
Republic of Ireland
J Bone Joint Surg Br,
Vol: 88 Page: 1183-6 September 2006
J. F. Quinlan; D. Duke; S. Eustace
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This study evaluated the efficacy of bilateral thoracoscopic sympathectomy in alleviating symptoms and improving quality of life in patients with hyperhidrosis or facial blushing
Abstract:
The aim of this study is to evaluate the efficacy of bilateral thoracoscopic sympathectomy in alleviating symptoms and improving quality of life in patients with hyperhidrosis or facial blushing and to investigate the occurrence, severity and possible underlying factors to compensatory sweating after surgery. One hundred and sixty-three patients in a single institution underwent more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings - General symptoms and signs - hyperhidrosis
Categories:
hyperhidrosis or facial blushing
Geography:
Northern Ireland
Interact Cardiovasc Thorac Surg,
Vol: 7 Page: 67-70 February 2008
R. Jeganathan; S. Jordan; M. Jones; S. Grant; O. Diamond; K. McManus; A. Graham; J. McGuigan
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This case report discusses a selection of cases managed with botulinum toxin and review the current data on use of the toxin to treat salivary gland disorders - Frey's syndrome, excessive salivation, hyperhidrosis, lacrimation and chronic rhinitis.
Abstract:
SUMMARY: The use of botulinum toxin to treat disorders of the salivary glands is increasing in popularity in recent years. Recent reports of the use of botulinum toxin in glandular hypersecretion suggest overall favourable results with minimal side-effects. However, few randomised clinical trials means that data are limited with respect to candidate suitability, treatment dosages, more...
International Classification:
Syndrome
Categories:
botulinum toxin
Geography:
Republic of Ireland
J Plast Reconstr Aesthet Surg,
Vol: 61 Page: 1024-8 September 2008
T. A. Laing; M. E. Laing; S. T. O'Sullivan
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This study aimed to explore General Practitioners in the Mid-West to ascertain their attitudes and practice in relation to breastfeeding
Abstract:
In light of the 1994 National Breastfeeding Policy and the 1999 Mid-Western Health Board (MWHB) Breastfeeding Strategy, a telephone survey of 164 General Practitioners (GPs) in the Mid-West was performed to ascertain their attitudes and practice in relation to breastfeeding. 95% believe breastfeeding promotion is part of their role and almost 40% consider GPs influential in the decision more...
International Classification:
Practice/knowledge - breastfeeding
Categories:
breastfeeding;
Geography:
Republic of Ireland
Ir Med J,
Vol: 97 Page: 268-70 October 2004
B. Finneran; K. Murphy
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This study examined buckle-related complications following surgical repair of retinal dialysis
Abstract:
AIM: To describe buckle-related complications following surgical repair of retinal dialysis. METHODS: A retrospective study of 28 consecutive cryobuckle procedures for retinal detachments secondary to retinal dialysis is reported, with particular attention directed towards postoperative complications relating to the buckle. Stata 8 statistical software and Fisher's exact test were used more...
International Classification:
Procedure - surgical repair of retinal dialysis
Categories:
surgical repair of retinal dialysis
Geography:
Republic of Ireland
Eye,
Vol: 22 Page: 485-90 April 2008
M. James; M. O'Doherty; S. Beatty
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