Irish Child Health Database - Peer Reviewed Papers
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This article discusses the use of growth hormone (GH) for small normal children ("idiopathic" short stature) with the following considerations: ethical (philosophical) grounds, cost-economic implications, and the rationale for treating
Abstract:
This paper argues against the use of growth hormone (GH) for small normal children ("idiopathic" short stature) with the following considerations: ethical (philosophical) grounds, cost-economic implications, and the rationale for treating normal physiological variation with a potent pharmacological agent. The author would prefer to see health and economic resources being more...
Geography:
Republic of Ireland
Arch Dis Child,
Vol: 91 Page: 270-2 March 2006
D. G. Gill
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The aim of this study was to audit the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome
Abstract:
The objective of the investigation was to determine the pattern of use of the Hakim (Medos) programmable valve implanted in patients with complex hydrocephalus and their clinical outcome. A prospective audit of patients with complex hydrocephalus undergoing Hakim programmable valve implantation between 1989 and 1994 in the United Kingdom and Ireland, was followed-up for a minimum of 5 more...
International Classification:
Procedure - Hakim valve implants
Categories:
Hakim valve implants
Geography:
Republic of Ireland and the United Kingdom
Br J Neurosurg,
Vol: 14 Page: 535-42 December 2000
A. D. Kay; A. J. Fisher; C. O'Kane; H. K. Richards; J. D. Pickard
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The aim of this study was to examine the linguistic anthropology which underpins the language dynamics of two Gaeltacht (Irish-speaking) areas
Abstract:
This paper presents an analysis of the linguistic anthropology which underpins the language dynamics of two Gaeltacht (Irish-speaking) areas, Ros Muc in Conamara, Co. Galway and Rath Cairn in Co. Meath. This research highlights what could be considered a socio-linguistic paradox: the community (Rath Cairn) which engages more vigorously in language maintenance endeavors, and exhibits a more...
International Classification:
Anthropology or ethnographic-language
Categories:
linguistic anthropology; language dynamics
Geography:
Republic of Ireland
Coll Antropol,
Vol: 28 Suppl 1 Page: 73-81 2004
C. O. Giollagain
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This article discusses a diatribe on dummies
Geography:
Republic of Ireland
Arch Dis Child,
Vol: 86 Page: 222 March 2002
D. Gill
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The aim of this study was to collate data on national policies for the use of fluoride in the seven European countries participating in the FLINT project
Abstract:
OBJECTIVES: The aim of this study was to collate data on national policies for the use of fluoride in the seven European countries participating in the FLINT project. METHODS: Policies on the use of fluoride were obtained for each of the study areas. Data collected included the presence of water fluoridation and regulations governing fluoride toothpaste and fluoride supplements. more...
International Classification:
Dental
Categories:
national policies for the use of fluoride
Geography:
International
Community Dent Oral Epidemiol,
Vol: 32 Suppl 1 Page: 69-73 April 2004
I. B. Arnadottir; C. E. Ketley; C. Van Loveren; L. Seppa; J. A. Cochran; M. Polido; T. Athanossouli; W. P. Holbrook; D. M. O'Mullane
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This article discusses a campaign to eradicate Meningitis C in Ireland
Abstract:
The new campaign to eradicate meningitis C marks Ireland's biggest ever immunisation programme, writes Moira Cassidy. more...
Geography:
Republic of Ireland
World of Irish Nursing,
Vol: 9 Page: 17-17 2001
M. Cassidy
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The aim of this study was to assess iron status in a sample of clinically well, Caucasian children and explore the complex factors which contribute to iron deficiency during infancy
Abstract:
OBJECTIVES: To assess iron status in a sample of clinically well, Caucasian children and explore the complex factors which contribute to iron deficiency during infancy. DESIGN: Infants recruited at birth and followed longitudinally at 1, 2, 3, 4, 5, 6, 9, 12, 24 and 36 months; feeding practices and socioeconomic data recorded. Iron status assessed using venous blood at 12, 24 and 36 more...
International Classification:
Other - iron status
Categories:
iron status
Geography:
Republic of Ireland
Public Health Nutr,
Vol: 1 Page: 93-100 June 1998
V. E. Freeman; J. Mulder; M. A. van't Hof; H. M. Hoey; M. J. Gibney
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The aim of this survey was to review published literature and perform a meta-analysis summarizing the evidence in support of an association between children born by Caesarean section and asthma
Abstract:
BACKGROUND: Children born by Caesarean section have modified intestinal bacterial colonization and consequently may have an increased risk of developing asthma under the hygiene hypothesis. The results of previous studies that have investigated the association between Caesarean section and asthma have been conflicting. OBJECTIVE: To review published literature and perform a more...
Categories:
association between children born by Caesarean section and asthma
Geography:
Northern Ireland
Clin Exp Allergy,
Vol: 38 Page: 629-33 April 2008
S. Thavagnanam; J. Fleming; A. Bromley; M. D. Shields; C. R. Cardwell
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The aim of this study was to investigate the influence of analytical design on the variability of published results in studies on sudden infant death syndrome
Abstract:
AIMS: To investigate the influence of analytical design on the variability of published results in studies of sudden infant death syndrome (SIDS). METHODS: The results of a prospective case-control study, of 203 cases of SIDS, and 622 control infants are presented. All variables significant on univariate analysis were included in a multivariate model analysed in nine stages, starting more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
analytical design of studies; -sudden infant death syndrome
Geography:
Republic of Ireland
Arch Dis Child,
Vol: 89 Page: 267-71 March 2004
T. Matthews; M. McDonnell; C. McGarvey; G. Loftus; M. O'Regan
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This study aimed to compare parent's experience of professional services in the aftermath of their child's death from sudden infant death both before and after the implementation of a National Model of Care for professionals in 1995
Abstract:
Sudden Infant Death Syndrome (SIDS) is any death occurring in an infant or young child which is unexpected by history and in which a thorough post mortem examination fails to demonstrate an adequate cause of death. The National Sudden Infant Death Register collects information on all sudden unexpected deaths in infants and young children occurring in Ireland. In this study, a comparison more...
International Classification:
Practice/knowledge - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
sudden infant death syndrome
Geography:
Republic of Ireland
Ir J Med Sci,
Vol: 168 Page: 237-41 1999 Oct-Dec
M. McDonnell; A. Cullen; B. Kiberd; M. Mehanni; T. Matthews
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The aim of this study was to examine a probabilistic estimation of fluoride intake by infants up to the age of 4 months from infant formula reconstituted with tap water in the fluoridated regions of Ireland
Abstract:
Two probabilistic models were developed to estimate the acute and chronic exposure to fluoride of exclusively formula-fed infants aged 0-4 months as a result of the consumption of infant formula reconstituted with fluoridated tap water in Ireland. The estimates were based on calculated infant formula consumption and accepted body weight standards, together with reported concentrations more...
International Classification:
Dental
Categories:
fluoride intake
Geography:
Republic of Ireland
Caries Res,
Vol: 38 Page: 421-9 2004 Sep-Oct
W. A. Anderson; I. Pratt; M. R. Ryan; A. Flynn
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The aim of the study was to compare physical and psychological outcomes in children presenting at Accident and Emergency, diagnosed with gastro-enteritis and admitted to hospital with those of a similar age, sex and severity of illness discharged home
Abstract:
OBJECTIVES: To compare physical and psychological outcomes in children presenting at Accident and Emergency Departments (A&E), diagnosed with gastro-enteritis and admitted to hospital with those of a similar age, sex and severity of illness discharged home. The physical and psychological well-being of children in these two groups, in the month after the episode, were compared as was more...
International Classification:
Other - outcomes at A&E
Categories:
physical and psychological outcomes at A&E
Geography:
Northern Ireland
Child: Care, Health & Development,
Vol: 31 Page: 555-562 2005
F. Small; F. Alderdice; C. McCusker; M. Stevenson; M. Stewart
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The aim of this study was to assess the health economics of realtime teledermatology compared with conventional care: an urban versus rural perspective
Abstract:
A randomized controlled trial was carried out to measure the cost-effectiveness of realtime teledermatology compared with conventional outpatient dermatology care for patients from urban and rural areas. One urban and one rural health centre were linked to a regional hospital in Northern Ireland by ISDN at 128 kbit/s. Over two years, 274 patients required a hospital outpatient more...
International Classification:
Evaluation of the effectiveness of teledermatology v. conventional assessment
Categories:
teledermatology v. conventional care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 7 Page: 108-18 2001
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; C. Evans; N. Hicks; P. Jacklin; H. E. Lotery; C. Mathews; J. Paisley; P. Reid; K. Steele; R. Wootton
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The aim of this study was to assess realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial
Abstract:
The clinical effectiveness of realtime teledermatology, store-and-forward teledermatology and conventional outpatient dermatological care were evaluated in a randomized control trial. A total of 204 patients took part--102 patients were randomized to the realtime teledermatology consultation, 96 of whose cases were also referred using a store-and-forward technique, and 102 to the more...
International Classification:
Evaluation of the effectiveness of two treatments - in dermatological care
Categories:
dermatological care
Geography:
Northern Ireland
J Telemed Telecare,
Vol: 6 Suppl 1 Page: S1-3 2000
M. A. Loane; S. E. Bloomer; R. Corbett; D. J. Eedy; N. Hicks; H. E. Lotery; C. Mathews; J. Paisley; K. Steele; R. Wootton
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This study examined visual outcome and complications in the treatment of retinoblastoma
Abstract:
The aim of this study was to look at the visual outcome and treatment complications of children diagnosed with Retinoblastoma during the years 1985-2003 inclusive. A retrospective review of all patients records was performed. Patient characteristics, treatment methods and complications were recorded. Twenty eight children presented to Temple street Hospital between 1985-2003. Six of more...
International Classification:
Neoplasms - Malignant neoplasms - retinoblastoma
Categories:
retinoblastoma
Geography:
Republic of Ireland
Ir Med J,
Vol: 98 Page: 17-20 January 2005
M. O'Doherty; B. Lanigan; F. Breathnach; A. O'Meara; B. Gallie; H. Chan; M. O'Keefe
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This aim of this study to evaluate the effectiveness of developmental screening in identifying learning disabilities in early childhood
Abstract:
This is a retrospective study of children under six years of age referred to the Brothers of Charity Early Intervention Services in County Galway, a service that caters for children under 6 years with learning disabilities. The aim in doing this study was to assess the value of routine developmental screening in identifying children with learning difficulties. This study also more...
International Classification:
Mental and behavioural disorders - Disorders of psychological development - learning disabilities
Categories:
developmental screening; learning disabilities
Geography:
Republic of Ireland
Ir Med J,
Vol: 94 Page: 148-50 May 2001
O. Flanagan; S. O. Nuallain
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The aim of this study was to compare Irish asylum seekers to other General Medical Scheme patients possessing Irish citizenship in terms of their utilisation of GP services, morbidity patterns and consultation outcomes
Abstract:
To compare Irish asylum seekers to other General Medical Scheme (GMS) patients possessing Irish citizenship in terms of their utilisation of GP services, morbidity patterns and consultation outcomes. A retrospective 1 year study on patient records in two Galway City practices was performed. All asylum seekers who were patients of the two practices were compared with two controls each more...
International Classification:
Health service provision
Categories:
morbidity patterns; consultation outcomes; -asylum seekers
Geography:
Republic of Ireland
Ir Med J,
Vol: 100 Page: 461-4 May 2007
J. D. McMahon; A. Macfarlane; G. E. Avalos; P. Cantillon; A. W. Murphy
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This study aimed to review and document the changing patterns in diagnosis, causes and treatment of bacterial infections of the central nervous system in a national neurosurgical unit
Abstract:
OBJECTIVES: To review and document the changing patterns in diagnosis, causes and treatment of bacterial infections of the central nervous system (CNS) in a national neurosurgical unit only in patients from whom a specimen was obtained for culture. METHODS: The case notes, radiological results and laboratory records of all 163 patients in our institution who underwent a neurosurgical more...
International Classification:
Hospital infection - in a neurosurgical unit
Categories:
bacterial infections of the central nervous system
Geography:
Republic of Ireland
Clin Microbiol Infect,
Vol: 9 Page: 803-9 August 2003
M. Roche; H. Humphreys; E. Smyth; J. Phillips; R. Cunney; E. McNamara; D. O'Brien; O. McArdle
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This study aimed to develop and validate a logistic regression model to predict need for admission and length of hospital stay in children presenting to the Emergency Department with bronchiolitis
Abstract:
OBJECTIVE: To develop and validate a logistic regression model to predict need for admission and length of hospital stay in children presenting to the Emergency Department with bronchiolitis. SETTING: Two children's hospitals in Dublin, Ireland. METHODS: We reviewed 118 episodes of bronchiolitis in 99 children admitted from the Emergency Department. Those discharged within 24 h by a more...
International Classification:
Effectiveness of measurement tool - a logistic regression model to predict need for admission
Geography:
Republic of Ireland
Eur J Emerg Med,
Vol: 11 Page: 265-72 October 2004
P. Walsh; S. J. Rothenberg; S. O'Doherty; H. Hoey; R. Healy
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This article discussed the use of general imaging strategies in abdominal pain in pediatrics
Abstract:
Acute abdominal pain is the most common condition necessitating surgical admission to a paediatric hospital. The vast majority of cases are due to either appendicitis or acute non-specific abdominal pain; however, there are many other conditions presenting with acute abdominal pain in childhood which can mimic appendicitis. Some of these conditions are rarely encountered in adult more...
Geography:
Republic of Ireland
Eur Radiol,
Vol: 14 Suppl 4 Page: L123-37 March 2004
R. Hayes
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The aim of this study was to investigate vascular abnormalities in large bowel biopsies from patients with isolated Hirschsprung's disease
Abstract:
Intestinal neuronal dysplasia (IND) is an intestinal motility disorder, which clinically resembles Hirschsprung's disease (HD). Adventitial fibromuscular dysplasia (AFMD) consists of proliferation of smooth muscle cells and collagen fibers in the adventitia of blood vessels. The purpose of this study was to investigate vascular abnormalities in large bowel biopsies from patients with more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease
Categories:
large bowel vascular abnormalities; - Hirschsprung's disease; Intestinal neuronal dysplasia
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 19 Page: 345-8 July 2003
U. Rolle; A. P. Piotrowska; P. Puri
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The aim of this study was to examine the distribution of c-Kit-positive interstitial cells of Cajal and their relationship to the autonomic intrinsic innervation in bowel specimens from patients with isolated hypoganglionosis
Abstract:
BACKGROUND/PURPOSE: C-Kit-positive interstitial cells of Cajal (ICCs) have a key role in the normal motility function and development of the bowel. They are pacemaker cells, which facilitate active propagation of electrical events and neurotransmission in the bowel wall. ICCs are present in the bowel as myenteric ICCs (ICC(my)S) and muscular ICCs (ICC(mus)S). The aim of this study was more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung's disease
Categories:
isolated hypoganglionosis
Geography:
Republic of Ireland
J Pediatr Surg,
Vol: 37 Page: 709-14 May 2002
U. Rolle; A. Yoneda; V. Solari; L. Nemeth; P. Puri
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This aim of this study was to examine uptake rates achieved for vaccinations administered in a school immunisation programme in a school year
Abstract:
This study sought to document uptake rates achieved for vaccinations administered in a School Immunisation Programme in a school year. In a population of 6436 children uptake rates of more than 95% were achieved for all the vaccines administered, except MMR in the 6th class cohort for which 94.7% was the uptake figure. The success of the programme was attributed to the fact that the more...
International Classification:
Vaccination
Categories:
vaccinations
Geography:
Republic of Ireland
Ir Med J,
Vol: 96 Page: 268-70 October 2003
J. Joyce-Cooney; G. Meagher; C. Quinn; I. Cavanagh
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This study examined the presentation, complications and hospital course of acute mastoiditis and ascertain had long term otological problems.
Abstract:
Acute mastoiditis, a destructive bacterial infection of the mastoid bone and air cell system, is relatively uncommon today but remains a potentially serious condition. There is a lack of information in the literature regarding the long term otological problems that children may face following an episode of this condition. OBJECTIVES: Our aim was to examine the presentation, more...
International Classification:
Diseases of the ear and mastoid process - Diseases of middle ear and mastoid -mastoiditis
Categories:
mastoiditis
Geography:
Republic of Ireland
J Laryngol Otol,
Vol: 122 Page: 233-7 March 2008
F. Glynn; L. Osman; M. Colreavy; H. Rowley; T. P. Dwyer; A. Blayney
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This study examined acute renal damage in infants after first urinary tract infection
Abstract:
Urinary tract infection (UTI) is one of the most common causes of unexplained fever in neonates. The aim of this study was to determine the incidence of urinary tract anomalies and acute renal damage in neonates who presented with first urinary tract infection in the first 8 weeks of life. We reviewed the records of 95 infants, who were hospitalised with UTI during a 6-year period more...
International Classification:
Diseases of the genitourinary system - Other diseases of urinary system-urinary tract infection
Categories:
urinary tract infection
Geography:
Republic of Ireland
Pediatr Nephrol,
Vol: 17 Page: 503-5 July 2002
S. Cascio; B. Chertin; A. Yoneda; U. Rolle; J. Kelleher; P. Puri
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This article discusses acute retention of urine in babies with meningomyelocele
Geography:
Northern Ireland
Eur J Pediatr Surg,
Vol: 11 Suppl 1 Page: S40-1 December 2001
S. Brown; D. Patterson; D. Marshall
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The aim of this study was to describe the age and sex profile of patients having cataract surgery by 2 consulting ophthalmic surgeons over an 18-year period
Abstract:
PURPOSE: To investigate the age and sex profile of patients having cataract surgery by 2 consulting ophthalmic surgeons over an 18-year period. SETTING: Waterford Regional Hospital, Waterford, Republic of Ireland. METHODS: Operating theater logbooks were reviewed, and all patients having cataract surgery between January 1986 and December 2003 in Waterford Regional Hospital were more...
International Classification:
Procedure - cataract surgery
Categories:
cataract surgery
Geography:
Republic of Ireland
J Cataract Refract Surg,
Vol: 31 Page: 2162-6 November 2005
P. O'Reilly; U. Mahmoud; P. Hayes; P. Tormey; S. Beatty
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The aim of this study was to examine the age at death of people with an intellectual disability in Ireland.
Abstract:
This study examined the age at death of people with an intellectual disability in Ireland. Using data from the National Intellectual Disability Database, the average age at death of 1120 people who died between 1996 and 2001 was 45.68 years, with no difference in lifespan between men and women. A more severe level of intellectual disability predicted shorter lifespan. In general, those more...
International Classification:
Mental and behavioural disorders - Mental retardation - intellectual disabilities
Categories:
intellectual disabilities
Geography:
Republic of Ireland
J Intellect Disabil,
Vol: 10 Page: 155-64 June 2006
K. E. Lavin; B. E. McGuire; M. J. Hogan
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This case report discusses agenesis of the corpus callosum with interhemispheric cyst, hepatic haemangioma and trisomy 21
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Report
Categories:
agenesis of the corpus callosum
Geography:
Republic of Ireland
Clin Dysmorphol,
Vol: 15 Page: 149-51 July 2006
A. M. Murphy; C. Brenner; S. Ann Lynch
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This study measured paediatric aphakic glaucoma, a major long term complication, after cataract surgery in children
Abstract:
BACKGROUND: Paediatric aphakic glaucoma presents months or years after cataract surgery in children and is a major long term complication. The results of surgical treatment are poor and many children require multiple and repeat procedures with poor visual outcomes. METHODS: 13 children (19 eyes) had Ahmed valve implantation surgery, nine of the children had previous procedures such as more...
International Classification:
Diseases of the eye and adnexa - Disorders of lens - paediatric aphakic glaucoma
Categories:
paediatric aphakic glaucoma
Geography:
Republic of Ireland
Br J Ophthalmol,
Vol: 89 Page: 855-8 July 2005
C. Kirwan; M. O'Keefe; B. Lanigan; U. Mahmood
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The aim of this study was to assess the incidence of airway complications in children less than one year of age whose airways were maintained during anesthesia with either a laryngeal mask airway or a facemask and oral airway
Abstract:
PURPOSE: To compare the incidence of airway complications in children less than one year of age whose airways were maintained during anesthesia with either a laryngeal mask airway (LMA) or a facemask and oral airway (FM-OA). METHODS: We randomized 49 - ASA class 1&2 - infants to an LMA or FM-OA group. All infants were undergoing minor general, urological or orthopedic procedures. more...
International Classification:
Evaluation of the effectiveness of procedures - airway maintanance
Categories:
airway complications
Geography:
Republic of Ireland
Can J Anaesth,
Vol: 47 Page: 315-8 April 2000
M. Harnett; B. Kinirons; A. Heffernan; C. Motherway; W. Casey
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This case report discusses airway management in a baby with femoral hypoplasia-unusual facies syndrome
Abstract:
We report the successful fibreoptic intubation through a laryngeal mask airway (LMA) while maintaining spontaneous respiration in an anaesthetized 3-month-old female infant with femoral hypoplasia-unusual facies syndrome, in whom direct laryngoscopy and intubation proved impossible. more...
International Classification:
Syndrome
Categories:
femoral hypoplasia-unusual facies syndrome
Geography:
Republic of Ireland
Paediatr Anaesth,
Vol: 12 Page: 461-4 June 2002
G. Iohom; B. Lyons; W. Casey
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The aim of the study was to assess the utility of alpha glutathione S-transferase (alphaGST) as a potential marker of intestinal ischemia-reperfusion injury in children after cardiac surgery
Abstract:
BACKGROUND: The aim of the study was to assess the utility of alpha glutathione S-transferase (alphaGST) as a potential marker of intestinal ischemia-reperfusion injury in children after cardiac surgery. METHODS: Twenty-six patients undergoing cardiac surgery were enrolled in this longitudinal experimental study. Blood samples were drawn for analysis at specified time points during more...
International Classification:
Diseases of the digestive system - Other diseases of intestines - intestinal ischemia-reperfusion injury
Categories:
intestinal ischemia-reperfusion injur
Geography:
Republic of Ireland
J Pediatr Surg,
Vol: 41 Page: 1526-31 September 2006
M. P. McMonagle; M. Halpenny; A. McCarthy; A. Mortell; F. Manning; C. Kilty; D. Mannion; A. E. Wood; M. T. Corbally
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The aim of study was to examine the expression of contractile and cytoskeleton proteins in smooth muscle contractile and distribution of interstitial cells of Cajal in megacystis microcolon intestinal hypoperistalsis syndrome bowel.
Abstract:
BACKGROUND/PURPOSE: Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is characterized by decreased or absent peristalsis. Gastrointestinal motility depends on the enteric nervous system, smooth muscle cells (SMCs), and the interstitial cells of Cajal (ICCs). Contractile and cytoskeleton proteinase are important structural and functional components of SMCs. The aim of more...
International Classification:
Syndrome - megacystis microcolon intestinal hypoperistalsis
Categories:
smooth muscle contractile; -megacystis microcolon intestinal hypoperistalsis syndrome
Geography:
Republic of Ireland
J Pediatr Surg,
Vol: 38 Page: 749-55 May 2003
A. P. Piotrowska; U. Rolle; B. Chertin; D. De Caluwe; A. Bianchi; P. Puri
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The aim of this study was to examine distribution of myenteric and muscular interstitial cells of Cajal in different parts of the colon in Hirschsprung disease
Abstract:
CONTEXT: Constipation or recurrent intestinal dysmotility problems are common after definitive surgical treatment in Hirschsprung disease (HD). c-Kit-positive interstitial cells of Cajal (ICCs) play a key role in the motility function and development of the gastrointestinal tract. Interstitial cells of Cajal that carry the tyrosine kinase receptor (c-Kit) develop as either myenteric more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease
Categories:
interstitial cells of Cajal; -Hirschsprung disease
Geography:
Republic of Ireland
Arch Pathol Lab Med,
Vol: 126 Page: 928-33 August 2002
U. Rolle; A. P. Piotrowska; L. Nemeth; P. Puri
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The aim of this study was to examine the expression of c-kit positive cells in the muscle layer of normal and obstructed ureteropelvic junction specimens
Abstract:
PURPOSE: Peristaltic contractions in the upper urinary tract serve to move urine from the kidney through the ureter to the bladder. Ureteropelvic junction (UPJ) obstruction is the most common cause of congenital hydronephrosis in children. To our knowledge the pathophysiology of UPJ obstruction is unknown. C-kit positive interstitial cells of Cajal (ICCs) are pacemaker cells that more...
International Classification:
Procedure - ureteropelvic junction obstruction
Categories:
c-kit positive cells; - ureteropelvic junction obstruction
Geography:
Republic of Ireland
J Urol,
Vol: 170 Page: 2420-2 December 2003
V. Solari; A. P. Piotrowska; P. Puri
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The aim of this study was to examine gene expression in a highly purified isolate of enterocytes taken from patients with active coeliac disease
Abstract:
BACKGROUND: Coeliac disease is a multifactorial inflammatory disorder of the intestine caused by ingestion of gluten in genetically susceptible individuals. Genes within the HLA-DQ locus are considered to contribute some 40% of the genetic influence on this disease. However, information on other disease causing genes is sparse. Since enterocytes are considered to play a central role in more...
International Classification:
Diseases of the digestive system - Other diseases of the digestive system - coeliac disease
Categories:
coeliac disease
Geography:
Republic of Ireland
BMC Genomics,
Vol: 9 Page: 377 2008
S. Bracken; G. Byrne; J. Kelly; J. Jackson; C. Feighery
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The aim of this study was to examine the impact of a designated quiet period on the neonatal intensive care unit and its influence on infant physiological and movement responses
Abstract:
The aim of the study was to measure the impact of a designated Quiet period on the NICU environment and its influence on the infants' physiological and movement responses. The study group comprised 10 preterm infants on assisted ventilation (mean gestational age 28.7 wk (range 24-32 wk), mean birthweight 1,322 g (range 600-2,060 g), mean age 5.2 d). The environment in which the infants more...
International Classification:
Growth and development
Categories:
infant physiological
Geography:
Republic of Ireland
Acta Paediatr,
Vol: 89 Page: 577-81 May 2000
M. Slevin; N. Farrington; G. Duffy; L. Daly; J. F. Murphy
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The aim of this study was to examine ambulatory peadiatrics and improvements in patient care
International Classification:
Health service provision
Categories:
ambulatory peadiatrics; patient care
Geography:
Northern Ireland
Irish Medical Journal,
Vol: 94 Page: 186%N 6 2001
J. E. Bothwell; P. Sheridan; A. H. Bell
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The aim of this study was to measure the effect of bed-sharing during the last sleep period on risk factors for sudden infant death syndrome
Abstract:
BACKGROUND: It is unclear if it is safe for babies to bed share with adults. In Ireland 49% of sudden infant death syndrome (SIDS) cases occur when the infant is bed-sharing with an adult. OBJECTIVE: To evaluate the effect of bed-sharing during the last sleep period on risk factors for SIDS in Irish infants. DESIGN: An 8 year (1994-2001) population based case control study of 287 SIDS more...
International Classification:
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome
Categories:
bed-sharing; sudden infant death syndrome
Geography:
Republic of Ireland
Arch Dis Child,
Vol: 91 Page: 318-23 April 2006
C. McGarvey; M. McDonnell; K. Hamilton; M. O'Regan; T. Matthews
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The aim of this study was to describe environmental factors and the exacerbation of atopic eczema in children
Abstract:
BACKGROUND: Possible exacerbating factors are a major concern of parents of children with atopic eczema (AE). However, there is minimal evidence for their direct role in leading to disease flares. OBJECTIVES: To assess the association between 'trigger factors' and disease flares in AE. METHODS: Twenty-five children with AE were recruited. Participants completed diaries, recording more...
International Classification:
Diseases of the skin and subcutaneous tissue - Dermatitis and eczema - eczema
Categories:
atopic eczema
Geography:
Republic of Ireland
Br J Dermatol,
Vol: 154 Page: 979-80 May 2006
S. M. Langan; J. F. Bourke; P. Silcocks; H. C. Williams
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The aim of this study was to examine parents' perceptions of postpartum family experiences
Abstract:
AIM: This paper is a report of a study to identify parents' perceptions of postpartum family experiences. BACKGROUND: There is a growing worldwide emphasis on family support. Government policy in the United Kingdom advocates a family-centred approach in which a core universal postbirth service is offered to all families with additional support for parents of children with complex needs. more...
International Classification:
Other - postpartum family experiences
Categories:
postpartum family experiences
Geography:
Northern Ireland
J Adv Nurs,
Vol: 61 Page: 38-50 January 2008
J. Christie; B. C. Poulton; B. P. Bunting
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This case report discusses a classically affected neonate with de Lange syndrome, an affected mother and probably affected maternal grandmother
Abstract:
The existence of familial de Lange syndrome has been documented in sibs and in parent-child families, but the inheritance pattern continues to be the cause of much debate. We describe a classically affected neonate with de Lange syndrome, an affected mother and probably affected maternal grandmother. These cases show evidence for a dominantly inherited syndrome with a de Lange phenotype. more...
International Classification:
Syndrome
Categories:
de Lange syndrome
Geography:
Northern Ireland
Clin Dysmorphol,
Vol: 12 Page: 241-4 October 2003
V. McConnell; T. Brown; P. J. Morrison
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The aim of the study was to conduct an open-label prospective study assessing the efficacy of activated protein C replacement therapy in patients with severe meningococcal septicemia, purpura fulminans, and multiorgan failure
Abstract:
Activated protein C (APC) is a natural anticoagulant that plays a pivotal role in coagulation homeostasis. Severe inherited or acquired deficiency results in a clinical syndrome called purpura fulminans. In addition, APC also appears to have potent cytokine-modifying properties and is protective in animal models of sepsis. The dual functional properties of APC are particularly relevant more...
International Classification:
Certain infectious and parasitic diseases - Other bacterial diseases - meningococcal disease
Categories:
severe meningococcal septicemia
Geography:
Republic of Ireland
Blood,
Vol: 96 Page: 3719-24 December 2000
B. White; W. Livingstone; C. Murphy; A. Hodgson; M. Rafferty; O. P. Smith
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This case report discusses an unusual case of respiratory symptoms in a toddler
International Classification:
Diseases of the respiratory system - Report
Categories:
respiratory symptoms
Geography:
Republic of Ireland
Br J Radiol,
Vol: 76 Page: 921-2 December 2003
M. C. Casey; D. Rafferty; M. O'Neill
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This study presented perioperative management of children with epidermolysis bullosa
Abstract:
BACKGROUND AND OBJECTIVE: Epidermolysis bullosa is a rare, genetically determined disorder characterized by excessive susceptibility of the skin and mucosa to separate from the underlying tissues after mechanical trauma. Patients suffering from this disease may have multiple medical problems, but the risk of anaesthesia is attributed mainly to oropharyngeal involvement; airway more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations - epidermolysis bullosa
Categories:
epidermolysis bullosa
Geography:
Republic of Ireland
Eur J Anaesthesiol,
Vol: 18 Page: 745-54 November 2001
G. Iohom; B. Lyons
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The aim of this study was to examine the ACE I/D genotype pattern in familial vesicoureteric reflux patients
Abstract:
Vesicoureteric reflux (VUR) is known to occur in families. In siblings of index patients with VUR, there is a much higher incidence (16% to 46%) than in the general population. The renin-angiotensin system plays an important role in renal development. Recently, it has been reported that angiotensin-converting enzyme (ACE) I/D gene polymorphism is a risk factor for renal parenchymal more...
International Classification:
Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux
Categories:
vesicoureteric reflux
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 17 Page: 308-11 May 2001
A. Yoneda; T. Oue; P. Puri
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This article discusses the annual scientific Meeting of the Association of Paediatric Anaesthetists of Great Britain and Ireland
Geography:
Republic of Ireland
Paediatr Anaesth,
Vol: 10 Page: 449-50 2000
G. H. Meakin
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This study examined five anomalous left coronary artery from pulmonary artery cases the present in a 5-year study period and discuss the incidence and clinical presentation of ALCAPA among infants
Abstract:
Anomalous left coronary artery from pulmonary artery (ALCAPA) is a rare congenital cardiac malformation. It presents predominantly in infancy with features of myocardial ischaemia or cardiac failure and may be mistaken for common paediatric conditions such as colic, reflux or bronchiolitis. With early surgical correction the prognosis is good, but awareness of this condition is more...
International Classification:
Congenital malformations, deformations and chromosomal abnormalities - Congenital malformation of the circulatory system - anomalous left coronary artery
Categories:
anomalous left coronary artery
Geography:
Republic of Ireland
Eur J Pediatr,
Vol: 167 Page: 43-6 January 2008
H. Brotherton; R. K. Philip
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The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors
Abstract:
OBJECTIVE: The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors using multiple logistic regression analysis. METHODS: A total of 1328 isolates of Streptococcus pneumoniae, 1894 Haemophilus influenzae and 845 Moraxella more...
International Classification:
Diseases of the respiratory system - lower respiratory pathogens
Categories:
lower respiratory pathogens
Geography:
Republic of Ireland and the United Kingdom
J Antimicrob Chemother,
Vol: 52 Page: 931-43 December 2003
R. Reynolds; J. Shackcloth; D. Felmingham; A. MacGowan
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The aim of this study was to measure apparent low immunisation uptake in Dublin and examine if this is a result of under-performance or under-recording
Abstract:
Through careful follow-up of a cohort, born March to August 1994, we have recorded the highest ever primary immunisation uptake figures for the Dublin area, with completed uptake for Diphtheria, Tetanus and Oral Polio of 92.1%, Haemophilus influenzae type b of 88.7%, Pertussis of 85.7% and Measles/Mumps/Rubella of 78.1%. Eastern Health Board uptake estimates for the same period are more...
International Classification:
Vaccination
Categories:
immunisation uptake
Geography:
Republic of Ireland
Ir Med J,
Vol: 93 Page: 239-40 November 2000
P. M. Harrington; C. Woodman; W. F. Shannon
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