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The aim of this study was to describe first neuronally expressed exon 1 at the dopa decarboxylase gene and two microsatellite markers flanking the gene were investigated for possible association with attention-deficit hyperactivity disorder
Abstract:
Dopa decarboxylase (DDC) is an enzyme which catalyses the decarboxylation of both dopa to dopamine and L-5 hydroxytryptophan to serotonin. Both catecholamines are major neurotransmitters of the mammalian nervous system. It has been suggested that genes involved in the dopaminergic system play a primary role in predisposing to attention deficit hyperactivity disorder (ADHD). In this more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
Republic of Ireland
Mol Psychiatry,
Vol: 6 Page: 420-4 July 2001
Z. Hawi; D. Foley; A. Kirley; M. McCarron; M. Fitzgerald; M. Gill
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This case report discusses a diagnosis of 5 cases of Cohen Syndrome among 3 families from the Irish Traveller Community in the West of Ireland
International Classification:
Syndrome
Categories:
Cohen syndrome
Geography:
Republic of Ireland
Clin Dysmorphol,
Vol: 16 Page: 257-9 October 2007
A. M. Murphy; O. Flanagan; K. Dunne; S. A. Lynch
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The aim of this study was to describe the distribution patterns of the subtypes and subgroups of BK polyomavirus among four patient populations with various immunosuppressive states and of various ethnic backgrounds
Abstract:
BK polyomavirus (BKV) is highly prevalent in the human population, infecting children without obvious symptoms and persisting in the kidney in a latent state. In immunosuppressed patients, BKV is reactivated and excreted in urine. BKV isolates worldwide are classified into four serologically distinct subtypes, I-IV, with subtype I being the most frequently detected. Furthermore, subtype more...
International Classification:
International committee on Taxonomy of Viruses - BK polyomavirus, herpesvirus, norovirus,Norwalk-like viruses, Astroviruses, rotavirus (4)
Categories:
BK polyomavirus
Geography:
International
J Gen Virol,
Vol: 87 Page: 3201-8 November 2006
H. Ikegaya; P. J. Saukko; R. Tertti; K. P. Metsarinne; M. J. Carr; B. Crowley; K. Sakurada; H. Y. Zheng; T. Kitamura; Y. Yogo
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The aim of this study was to examine examined the alpha 4 receptor, one of the sites of action of ABT-418 to examine the effect of nicotine in families with ADHD
Abstract:
Attention deficit hyperactivity disorder (ADHD) is a highly heritable, common psychiatric disorder that presents in childhood and that probably involves several genes. There are several lines of evidence suggesting that the nicotinic system may be functionally significant in ADHD: (a) nicotine promotes the release of dopamine and has been shown to improve attention in adults with ADHD, more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
Republic of Ireland and the United Kingdom
Psychiatr Genet,
Vol: 11 Page: 37-40 March 2001
L. Kent; F. Middle; Z. Hawi; M. Fitzgerald; M. Gill; C. Feehan; N. Craddock
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The aim of this study was to examine the prevalence, clinical characteristics, management and changes in survival over time of vertically HIV-infected infants developing PCP and/or CMV infection
Abstract:
OBJECTIVES: The outcome of Pneumocystis carinii pneumonia (PCP) in HIV-infected infants is poor, and the role of cytomegalovirus (CMV) co-infection in the course and outcome of PCP is unclear. This study describes the prevalence, clinical characteristics, management and changes in survival over time of vertically HIV-infected infants developing PCP and/or CMV infection. METHODS: Data on more...
International Classification:
Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV
Categories:
HIV-infected
Geography:
Republic of Ireland and the United Kingdom
Aids,
Vol: 15 Page: 335-9 February 2001
A. J. Williams; T. Duong; L. M. McNally; P. A. Tookey; J. Masters; R. Miller; E. G. Lyall; D. M. Gibb
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The aim of this study was to examine differences in the International Multi-Centre attention-deficit hyperactivity disorder Gene Project
Abstract:
The International Multi-Centre ADHD Gene sample consists of 674 families from eight countries (Belgium, England, Germany, Holland, Ireland, Israel, Spain, and Switzerland) ascertained from clinics for combined-type attention definity hyperactivity disorder in an offspring. 863 SNPs were successfully genotyped across 47 autosomal genes implicated in psychiatric disorders yielding a more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
International Multi-Centre attention-deficit hyperactivity disorder Gene Project
Geography:
International
Genet Epidemiol,
Vol: 32 Page: 98-107 February 2008
B. M. Neale; P. C. Sham; S. Purcell; T. Banaschewski; J. Buitelaar; B. Franke; E. Sonuga-Barke; R. Ebstein; J. Eisenberg; A. Mulligan; M. Gill; I. Manor; A. Miranda; F. Mulas; R. D. Oades; H. Roeyers; A. Rothenberger; J. Sergeant; H. C. Steinhausen; E. Taylor; M. Thompson; W. Chen; K. Zhou; P. Asherson; S. V. Faraone
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