Irish Child Health Database - Peer Reviewed Papers
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The aim of the study was to examine traditional and otic capsule classification system of temporal bone fractures for clinical relevance
Abstract:
Objectives: To compare the traditional and otic capsule classification system of temporal bone fractures for clinical relevance. Design: A retrospective review of all patients with a radiological diagnosis of a skull-base fracture over a 5-year period. Setting: All patients were seen at Beaumont Hospital, the national tertiary referral centre for Neuro-otology. Participants: Patients more...
International Classification:
Injury, poisoning and certain other consequences of external causes - fractures
Categories:
temporal bone fractures
Geography:
Republic of Ireland
Clinical Otolaryngology,
Vol: 31 Page: 287-291 2006
M. A. Rafferty; R. Mc Conn Walsh; M. A. Walsh
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The aim of this study was to describe the clinical features and assess the prevalence of Familial Glucocorticoid Deficiency amongst Irish Travelers in the Republic of Ireland and describe their phenotype.
Abstract:
Context: Familial glucocorticoid deficiency (FGD) is an autosomal recessive disorder characterized by distinct clinical, biochemical, and genetic abnormalities. The prevalence of FGD is unknown, with the likelihood that cases remain undiagnosed. We noted a significant proportion of our FGD cases are Irish Travelers. Irish Travelers are an endogamous nomadic group ethnically and more...
International Classification:
Endocrine, nutritional and metabolic disease - Familial Glucocorticoid Deficiency
Categories:
Familial Glucocorticoid Deficiency; Travellers
Geography:
Republic of Ireland
Journal of Clinical Endocrinology and Metabolism,
Vol: 93 Page: 2896-2899 2008
S. M. P. O'Riordan; S. A. Lynch; P. C. Hindmarsh; L. F. Chan; A. J. L. Clark; C. Costigan
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The aim of this study was to describe paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain derived neurotrophic factor gene with susceptibility to attention-deficit hyperactivity disorder
Abstract:
Attention deficit hyperactivity disorder (ADHD) is a common, highly heritable, neurodevelopmental disorder with onset in early childhood. Genes involved in neuronal development and growth are, thus, important etiological candidates and brain-derived neurotrophic factor (BDNF), has been hypothesized to play a role in the pathogenesis of ADHD. BDNF is a member of the neurotrophin family more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
Republic of Ireland and the United Kingdom
Molecular Psychiatry,
Vol: 10 Page: 939-943 2005
L. Kent; E. Green; Z. Hawi; A. Kirley; F. Dudbridge; N. Lowe; R. Raybould; K. Langley; N. Bray; M. Fitzgerald; M. J. Owen; M. C. O'Donovan; M. Gill; A. Thapar; N. Craddock
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This case report discusses the inclusion of a pupil with a severe general learning difficulty in a four-teacher mainstream primary school, located in rural Ireland
Abstract:
The aim of this study was to examine the inclusion of a pupil with a severe general learning difficulty in a four-teacher mainstream primary school, located in rural Ireland. The research employed a qualitative multiple operationism approach to data collection. Data were analysed qualitatively, and quantitative reporting and display procedures were also employed. This paper focuses on more...
International Classification:
Mental and behavioural disorders - Report
Categories:
learning difficulties
Geography:
Republic of Ireland
European Journal of Special Needs Education,
Vol: 20 Page: 41-56 2005
E. Ring; J. Travers
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The aim of this study was to examine neonatal thyroid-stimulating hormone screening and population iodine
Abstract:
Background: The distribution of neonatal blood thyroid-stimulating hormone (TSH) concentrations has been used as an index reflecting population dietary iodine intake, with higher concentrations being indicative of lower iodine intake. We examined this distribution in neonates born in Ireland, where the pregnant population has shown a recent decline in urinary iodine (UI) excretion. Our more...
International Classification:
Endcrine, nutritional and metabolic disease - neonatal thyroid-stimulating hormone
Categories:
thyroid-stimulating hormone screening; population iodine
Geography:
Republic of Ireland
Thyroid,
Vol: 18 Page: 883-888 2008
R. Burns; P. D. Mayne; C. O'Herlihy; D. F. Smith; M. Higgins; A. Staines; P. P. A. Smyth
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The aim of the study was to compare the gut flora of Irish breastfed and formula-fed neonates aged between birth and 6 weeks old
Abstract:
The exact composition of the complex microsystem that constitutes the gut flora continues to be explored as molecular methodology supplements traditional microbiological studies. The current study reports a random analysis of the faecal flora composition for 31 neonates in the 0-1 day age group, 41 neonates aged 2-5 days and 33 6-week-old neonates. All infants, born at the National more...
International Classification:
Breastfeeding +/- formulae milk
Categories:
breastfed
Geography:
Republic of Ireland
Microbial Ecology in Health and Disease,
Vol: 17 Page: 163-168 2005
G. Cooke; J. Behan; N. Clarke; W. Gorman; M. Costello
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The aim of the study was to compare pertussis surveillance systems in Europe
Abstract:
We compared pertussis surveillance systems of 16 European countries in the period 1998-2002. In twelve out of sixteen countries the system covered the general population. Ten countries relied on WHO case definition for surveillance of pertussis. Eleven countries applied laboratory tests, and eight of them used PCR for case confirmation. The proportion of hospitalised rates in children more...
International Classification:
Health service provision - pertussis surveillance systems
Categories:
pertussis surveillance systems
Geography:
International
Vaccine,
Vol: 25 Page: 291-297 2007
A. E. Tozzi; E. Pandolfi; L. P. Celentano; M. Massari; S. Salmaso; M. L. C. d Atti
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The aim of this study was to audit emergency contraceptive use by Irish teenagers
Abstract:
Objective: To audit teenagers attending a family planning clinic requesting emergency contraception. Methods: A non-judgemental, relaxed, confidential interview was carried out. Results: Many young Irish women become sexually active at a young age. Many teenagers appear to have problems using condoms correctly while others are taking chances by not using any method of contraception. more...
International Classification:
Factors influencing health status and contact with health services - persons encountering health services for examination and investigation - contraceptive use
Categories:
emergency contraceptive use
Geography:
Republic of Ireland
European Journal of Contraception and Reproductive Health Care,
Vol: 10 Page: 26-28 2005
S. Jones
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The aim of this study was to analyses the aetiology and demographics of a cohort of spine trauma in the West of Ireland
regional trauma unit: A 4-year study
Abstract:
Currently there is a lack of information on the full spectrum of spine trauma presenting to medical services in a defined geographic area. This study analyses the aetiology and demographics of a cohort of spine trauma in the West of Ireland. A regional trauma unit has been investigated for a 51-month period. Two hundred and eighty-five cases admitted with spine trauma were documented. more...
International Classification:
Injury, poisoning and certain other consequences of external causes - injury
Categories:
spine trauma
Geography:
Republic of Ireland
Injury,
Vol: 39 Page: 436-442 2008
S. J. Roche; P. A. Sloane; J. P. McCabe
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The aim of this study was to investigated whether polymorphisms in genes encoding these cytokines, and in those encoding anti-inflammatory IL-10 and IL-1Ra, are associated with the outcome in patients with meningococcal disease
Abstract:
Patients with meningococcal disease have increased plasma levels of proinflammatory cytokines IL-6, IL-1(beta), and TNF-(alpha), with higher levels associated with fatal outcome. This study investigated whether polymorphisms in genes encoding these cytokines, and in those encoding anti-inflammatory IL-10 and IL-1Ra, are associated with the outcome in patients with meningococcal disease. more...
International Classification:
Certain infectious and parasitic diseases - Other bacterial diseases - meningococcal disease
Categories:
cytokines; -meningococcal disease
Geography:
Republic of Ireland
Genes and Immunity,
Vol: 4 Page: 533-540 2003
J. Balding; C. M. Healy; W. J. Livingstone; B. White; L. Mynett-Johnson; M. Cafferkey; O. P. Smith
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This article discusses guidelines for management of childhood arthritis
Geography:
the United Kingdom
Rheumatology,
Vol: 40 Page: 1309-1312 2001
R. G. Hull
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The aim of this study was to assess the effectiveness of high-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma
Abstract:
Background: The current standard treatment for patients with high-risk neuroblastoma includes initial induction chemotherapy with a 21-day interval between induction treatments. We aimed to assess whether an intensive chemotherapy protocol that had a 10-day interval between treatments would improve event-free survival (EFS) in patients aged 1 year or over with high-risk neuroblastoma. more...
International Classification:
Evaluation of the effectiveness of treatments - neuroblastoma
Categories:
chemotherapy for neuroblastoma
Geography:
International
The Lancet Oncology,
Vol: 9 Page: 247-256 2008
A. D. Pearson; C. R. Pinkerton; I. J. Lewis; J. Imeson; C. Ellershaw; D. Machin
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The aim of this study was to examine intelligence in DSM-IV combined type attention-deficit/hyperactivity disorder is predicted by either dopamine receptor/transporter genes or other previously identified risk alleles
Abstract:
A major goal of genetic studies of attention deficit hyperactivity disorder (ADHD) is to identify individual characteristics that might help segregate the disorder's inherent heterogeneity. [Mill et al. (2006); Arch Ger Psychiatry 63:462-469] recently reported a potentially important association between two dopamine-related risk polymorphisms (DRD4 variable number tandem repeat (VNTR) more...
International Classification:
Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder
Categories:
attention-deficit hyperactivity disorder
Geography:
International
American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics,
Vol: 147 Page: 316-319 2008
E. J. S. Sonuga-Barke; K. J. Brookes; J. Buitelaar; R. Anney; P. Bitsakou; D. Baeyens; C. Buschgens; W. Chen; H. Christiansen; J. Eisenberg; J. Kuntsi; I. Manor; A. Melia; A. Mulligan; N. Rommelse; U. C. Muller; H. Uebel; T. Banaschewski; R. Ebstein; B. Franke; M. Gill; A. Miranda; R. D. Oades; H. Roeyers; A. Rothenberger; J. Sergeant; H. C. Steinhausen; M. Thompson; E. Taylor; P. Asherson; S. V. Faraone
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The aim of this study was to examine the prevalence of multiple sclerosis in Co. Wexford in the south east of Ireland and Co. Donegal in the north west, and to establish whether a variation in prevalence of MS exists within Ireland
Abstract:
Background: Northern Ireland has a high and rising prevalence rate of multiple sclerosis (MS). The most recent survey in 1996 found a rate of 168.7/100 000. Recorded prevalence rates for the south of Ireland, including County Wexford, have been markedly lower and seemed to suggest the existence of a prevalence gradient within the island. Objectives: To compare the prevalence of multiple more...
International Classification:
Diseases of the nervous system - Demyelinating diseases of the central nervous system - multiple sclerosis
Categories:
multiple sclerosis
Geography:
Republic of Ireland
Journal of Neurology, Neurosurgery and Psychiatry,
Vol: 75 Page: 572-576 2004
C. McGuigan; A. McCarthy; C. Quigley; L. Bannan; S. A. Hawkins; M. Hutchinson
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This article discusses management guidelines for arthritis in children
Geography:
the United Kingdom
Rheumatology,
Vol: 40 Page: 1308%N 11 2001
R. G. Hull
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The aim of this study was to examine the incidence, survival and aetiology of out-of-hospital sudden cardiac death in the West of Ireland for the year 2005
Abstract:
Aims: There is a paucity of published data on prospectively identified rates of out-of-hospital sudden cardiac death (SCD). We sought to determine the incidence, survival and aetiology of out-of-hospital SCD in the West of Ireland for the year 2005. Methods and results: Data from emergency room resuscitation records were collected throughout the year from all hospitals in the West of more...
International Classification:
Diseases of the circulatory system - Other forms of heart disease - sudden cardiac death
Categories:
sudden cardiac death
Geography:
Republic of Ireland
European Heart Journal,
Vol: 29 Page: 1418-1423 2008
R. Byrne; O. Constant; Y. Smyth; G. Callagy; P. Nash; K. Daly; J. Crowley
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The aim of this study was to examine the incidence and outcome of heart muscle disease-induced heart failure in children
Abstract:
BACKGROUND: We undertook the first prospective, national, multicenter study to describe the incidence and outcome of heart muscle disease-induced heart failure in children. METHODS AND RESULTS: Data were collected on patients admitted to a hospital through 2003 with a first episode of heart failure in the absence of congenital heart disease. All 17 pediatric cardiac centers in the more...
International Classification:
Other - heart muscle disease-induced heart failure
Categories:
heart muscle disease-induced heart failure
Geography:
Republic of Ireland and the United Kingdom
Circulation,
Vol: 117 Page: 79-84 2008
R. E. Andrews; M. J. Fenton; D. A. Ridout; M. Burch
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The aim of this study was to examine the incidence of invasive pneumococcal disease in the Republic of Ireland and to examine the associated isolates
Abstract:
A national study was undertaken to investigate the incidence of invasive pneumococcal disease in the Republic of Ireland and to examine the associated isolates. In 1999, 144 S. pneumoniae isolates, all recovered from cases of invasive disease, were received from 12 microbiology laboratories. The incidence of invasive pneumococcal disease was estimated to be 6.6/100,000 population. All more...
International Classification:
Bacterium - Invasive pneumococca
Categories:
invasive pneumococca
Geography:
Republic of Ireland
Journal of Clinical Microbiology,
Vol: 41 Page: 3641-3648 2003
D. Bennett; B. Lennon; H. Humphreys; M. Cafferkey
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The aim of this study was to examine REEP1 mutation spectrum and genotype/phenotype correlation for hereditary spastic paraplegia type 31
Abstract:
Mutations in the receptor expression enhancing protein 1 (REEP1) have recently been reported to cause autosomal dominant hereditary spastic paraplegia (HSP) type SPG31. In a large collaborative effort, we screened a sample of 535 unrelated HSP patients for REEP1 mutations and copy number variations. We identified 13 novel and 2 known REEP1 mutations in 16 familial and sporadic patients more...
International Classification:
Diseases of the nervous system - Cerebral palsy and other paralytic syndromes - spastic paraplegia
Categories:
hereditary spastic paraplegia type 31
Geography:
International
Brain,
Vol: 131 Page: 1078-1086 2008
C. Beetz; R. Schule; T. Deconinck; K. N. Tran-Viet; H. Zhu; B. P. H. Kremer; S. G. M. Frints; W. A. G. Van Zelst-Stams; P. Byrne; S. Otto; A. O. H. Nygren; J. Baets; K. Smets; B. Ceulemans; B. Dan; N. Nagan; J. Kassubek; S. Klimpe; T. Klopstock; H. Stolze; H. J. M. Smeets; C. T. R. M. Schrander-Stumpel; M. Hutchinson; B. P. Van De Warrenburg; C. Braastad; T. Deufel; M. Pericak-Vance; L. Schols; P. De Jonghe; S. Zuchner
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This study examined robotically assisted minimally invasive surgery
Abstract:
Introduction: Reports of robotically assisted minimal access surgery (RMAS) in the adult patient population have increased over the last several years. Few reports have addressed RMAS in pediatric patients. We present our initial RMAS experience with the da Vinci(registered trademark) Surgical System (Intuitive Surgical, Sunnyvale, California), and discuss technical considerations, more...
International Classification:
Procedure - invasive surgery
Categories:
assisted minimally invasive surgery
Geography:
United States of America
Pediatric Endosurgery and Innovative Techniques,
Vol: 7 Page: 385-402 2003
B. N. Luebbe; R. Woo; S. A. Wolf; M. S. Irish
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The article discusses sedation of children by non-anaesthetists
Geography:
Republic of Ireland
British Journal of Anaesthesia,
Vol: 85 Page: 659-661 2000
M. E. McBrien; P. A. Farling; R. Mackenzie; D. J. Hatch; M. R. Sury
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The aim of the study was to compare Quality of life among individuals with Cerebal Palsy
Abstract:
Background: Little is known about the quality of life (QoL) of disabled children. We describe self-reported QoL of children with cerebral palsy, factors that influence it, and how it compares with QoL of the general population. Methods: 1174 children aged 8-12 years were randomly selected from eight population-based registers of children with cerebral palsy in six European countries and more...
International Classification:
Diseases of the nervous system - Cerebral palsy and other paralytic syndromes - cerebral palsy
Geography:
International
Lancet,
Vol: 369 Page: 2171-2178 2007
H. O. Dickinson; K. N. Parkinson; U. Ravens-Sieberer; G. Schirripa; U. Thyen; C. Arnaud; E. Beckung; J. Fauconnier; V. McManus; S. I. Michelsen; J. Parkes; A. F. Colver
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The aim of this study was to examine the prevalence of respiratory symptoms and the level of diagnosis, and to compare determinants of asthma and severe wheeze in two countries
Abstract:
Background: Environmental, cultural and health care differences may account for variation among countries in the prevalence of asthma and respiratory symptoms in teenagers. Objective: To examine the prevalence of respiratory symptoms and the level of diagnosis, and to compare determinants of asthma and severe wheeze in two countries. Methods: Self-completion questionnaires based on the more...
International Classification:
Diseases of the respiratory system - Chronic lower respiratory diseases - asthma
Categories:
respiratory symptoms; asthma; severe wheeze
Geography:
Northern Ireland and the Republic of Ireland
Clinical and Experimental Allergy,
Vol: 33 Page: 96-100 2003
J. W. G. Yarnell; M. R. Stevenson; J. MacMahon; M. Shields; E. E. McCrum; C. C. Patterson; A. E. Evans; P. J. Manning; L. Clancy
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This article discusses The Child Health Questionnaire (CHQ-PF50) studies: Sincere congratulations and a sincere plea for terminological accurary
Geography:
Republic of Ireland
Clinical and Experimental Rheumatology,
Vol: 20 Page: 436-437 2002
F. T. Houghton; N. Ruperto; A. Martini
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The aim of the study was to evaluate the comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region
Abstract:
The European sero-epidemiology network (ESEN2) aims to standardise serological surveillance of varicella zoster virus (VZV) in 11 participant countries. In each country, serum banks were collected between 1996 and 2003 and tested for VZV antibodies. Assay results were standardised so that international comparisons could be made. Age-specific forces of infection were calculated for three more...
International Classification:
Certain infectious and parasitic diseases - Viral infections characterized by skin and mucous membrane lesions - varicella
Categories:
varicella zoster virus
Geography:
International
Vaccine,
Vol: 25 Page: 7866-7872 2007
A. Nardone; F. de Ory; M. Carton; D. Cohen; P. van Damme; I. Davidkin; M. C. Rota; H. de Melker; J. Mossong; M. Slacikova; A. Tischer; N. Andrews; G. Berbers; G. Gabutti; N. Gay; L. Jones; S. Jokinen; G. Kafatos; M. V. M. de Aragon; F. Schneider; Z. Smetana; B. Vargova; R. Vranckx; E. Miller
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This study examined the efficacy and tolerability of combination antiretroviral therapy in pregnancy
Abstract:
Antiretroviral therapy (ART) and Caesarean section (CS) delivery significantly reduce the risk of vertically transmitted HIV infection. Attention must focus on determining the optimal management strategy for HIV-positive pregnancies. Guidelines must reflect not only the activity and tolerability of combination ART in pregnancy for mother and infant and the potential short and long-term more...
International Classification:
Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV
Categories:
HIV antiretroviral therapy
Geography:
Republic of Ireland
International Journal of STD and AIDS,
Vol: 11 Page: 220-223 2000
S. M. Clarke; F. Mulcahy; C. M. Healy; S. Condon; K. M. Butler
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The aim of this study was to examine research on cross-national collaboration through Information and Communications Technology within the statutory curricula of 10 special schools in Northern Ireland and the Republic of Ireland.
Abstract:
This paper reports research on cross-national collaboration through Information and Communications Technology (ICT) within the statutory curricula of 10 special schools in Northern Ireland and the Republic of Ireland. Working in north-south paired classes, the pupils carried out joint tasks using asynchronous computer conferencing and videoconferencing. The full spectrum of learning more...
International Classification:
Other - cross-national collaboration through Information and Communications Technology
Categories:
cross-national collaboration through Information and Communications Technology
Geography:
Northern Ireland and the Republic of Ireland
European Journal of Special Needs Education,
Vol: 19 Page: 225-240 2004
L. Abbott; R. Austin; A. Mulkeen; N. Metcalfe
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The aim of this study was to describe current clinical practice in liver transplantation in the United Kingdom and Ireland, to provide overall 1-year graft and patient survival rates, and to study some preoperative risk factors
Abstract:
Background: The aim of this study was to describe current clinical practice in liver transplantation in the UK and Ireland, to provide overall 1-year graft and patient survival rates, and to study some preoperative risk factors. Methods: All patients receiving a liver transplant in the UK or Ireland between 1 March 1994 and 30 September 1998 were included. Data were collected on more...
International Classification:
Organ transplants - liver transplants
Categories:
clinical practice in liver transplants
Geography:
Republic of Ireland and the United Kingdom
British Journal of Surgery,
Vol: 88 Page: 52-58 2001
P. Hartley; A. Petruckevitch; B. Reeves; K. Rolles
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This study aimed to evaluate the indications, surgical techniques and post-operative problems seen in children with Down syndrome fitted with bone anchored hearing aids
Abstract:
Objective: To evaluate the indications, surgical techniques and post-operative problems seen in children with Down syndrome fitted with bone anchored hearing aids (BAHA(registered trademark)). Methods: A postal survey of all registered United Kingdom and Ireland BAHA(registered trademark) centres. Results: There was a 98% response rate to the survey. Eighty-one centres in the United more...
International Classification:
Practice/knowledge - bone anchored hearing aids
Categories:
Down syndrome; bone anchored hearing aids
Geography:
Republic of Ireland and the United Kingdom
International Journal of Pediatric Otorhinolaryngology,
Vol: 70 Page: 981-986 2006
P. Z. Sheehan; P. S. Hans
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Ultrasonography in neonatal hip instability reduced the need for splints: Commentary
International Classification:
Commentry
Geography:
Republic of Ireland and the United Kingdom
Journal of Bone and Joint Surgery - Series A,
Vol: 85 Page: 1623%N 8 2003
J. H. Wedge
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