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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » B » Blood Coagulation Factors/immunology

Blood Coagulation Factors/immunology

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1. Recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high-responding inhibitors

This study examined recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high-responding inhibitors

Abstract:

The development of inhibitors to therapeutic factor concentrates in children with haemophilia A or B is a troublesome complication of factor replacement therapy. Immune tolerance protocols have been developed to eliminate the inhibitors, and these are successful in approximately 80% of children. However, acute bleeding episodes require treatment with a factor (F)VIII or FIX bypassing more...

International Classification:

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - Coagulation defects, purpura and other haemorrhagic conditions - haemophilia

Categories:

haemophilia

Geography:

Republic of Ireland

Pathophysiol Haemost Thromb, Vol: 32 Suppl 1 Page: 22-5 2002
O. P. Smith

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