Irish Child Health Database - Peer Reviewed Papers
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Acute demyelinating events with rhombencephalitis: a high-risk subgroup in children
Published in:
Eur J Paediatr Neurol, Vol: 12, Page: 137-40
Publication Date:
March 2008
Aims & Objectives:
The aim of this study was to examine four children who had cerebellar involvement with significant mass effect in posterior fossa on CT and MRI brain - finding acute demyelinating events with rhombencephalitis
Abstract:
Acute, acquired demyelination of central nervous system in childhood leads to a variety of clinical phenotypes dependant on the site of demyelination and presence of encephalopathy. Posterior fossa involvement is seen in over third of cases in childhood. We report on four children who had cerebellar involvement with significant mass effect in posterior fossa on CT and MRI brain. This subgroup of children have significant cerebellar and brainstem swelling (rhombencephalitis) and is difficult to distinguish entirely on clinical grounds from other children with acute demyelinating events at presentation.
Authors:
Study Type:
Study Papers » Case Study » Descriptive Studies - Without a comparision
Categories:
rhombencephalitis
International Classification:
Other - rhombencephalitis
Keywords:
- Brain Edema/pathology
- Brain/pathology
- Cerebellum/pathology
- Child
- Child, Preschool
- Cranial Fossa, Posterior/ pathology
- Demyelinating Diseases/ pathology
- Encephalitis/complications/ pathology
- Female
- Humans
- Magnetic Resonance Imaging
- Male
- Tomography, X-Ray Computed
Geography:
Republic of Ireland (Dublin Our Lady's Hospital)