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Irish Child Health Database - Peer Reviewed Papers

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You are here: Irish Child Health Database » Study Papers » Descriptive Studies - Without a comparision » Case Report Study

False positive Kleihauer tests and unnecessary administration of anti-D immunoglobulin
Published in:

Clin Lab Haematol, Vol: 25, Page: 405-8

Publication Date:

December 2003

Aims & Objectives:

This obstetric case shows two false negative Kleihauer tests and two persistently positive Kleihauer tests leading to unnecessary administration of anti-D immunoglobulin

Abstract:

This obstetric case shows two false negative Kleihauer tests and two persistently positive Kleihauer tests leading to unnecessary administration of anti-D immunoglobulin. A diagnosis of hereditary persistence foetal haemoglobin (HPFH) was only confirmed by access to flow cytometry making use of both anti-HbF and anti-D labels. The case highlights the importance of a high index of clinical suspicion for HPFH and the importance of access to flow cytometry estimation of minor RhD red cell populations postnatally in RhD-negative mothers.

Authors:

R. Iyer; B. McElhinney; N. Heasley; M. Williams; K. Morris

Study Type:

Study Papers » Case Report Study » Descriptive Studies - Without a comparision

Categories:

unnecessary administration of anti-D immunoglobulin

International Classification:

Health service provision

Keywords:
Geography:

Northern Ireland (Northern Ireland)