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Cerebral palsy after maternal trauma in pregnancy
Published in:
Dev Med Child Neurol, Vol: 49, Page: 700-6
Publication Date:
September 2007
Aims & Objectives:
The aim of this study was to examine cases of cerebal palsy in infants born at term to mothers who earlier in the pregnancy had been involved in accidents without suffering overt abdominal injury, placental abruption, or premature onset of labour
Abstract:
Ten children (six males, four females) with spastic (n=9) and mixed spastic-dyskinetic (n=1) cerebral palsy were born at term to mothers who earlier in the pregnancy had been involved in accidents without suffering overt abdominal injury, placental abruption, or premature onset of labour. At follow-up (at ages 2-24y), Gross Motor Function Classification System levels were II (n=7) and V (n=3). Cognitive level was normal in five patients, while learning disability was mild to moderate in two and severe in three. Magnetic resonance imaging of the brain in all children, assessed blind to the dates of maternal trauma in pregnancy, showed lesions consistent with prenatal vascular insult at the time of the trauma. Feasible mechanisms of brain injury include reduced placental blood flow and/or placental embolization.
Authors:
Study Type:
Study Papers » Case Study » Descriptive Studies - Without a comparision
Categories:
cerebral palsy
International Classification:
Diseases of the nervous system - Cerebral palsy and other paralytic syndromes - cerebral palsy
Keywords:
- Adult
- Brain/ pathology
- Cerebral Palsy/ etiology/pathology/physiopathology
- Female
- Gestational Age
- Humans
- Learning Disorders/ etiology/pathology/physiopathology
- Magnetic Resonance Imaging
- Male
- Pregnancy
- Pregnancy Complications
- Pregnancy Trimester, Second
- Pregnancy Trimester, Third
- Psychomotor Performance
- Severity of Illness Index
Geography:
Republic of Ireland (Dublin)