Irish Child Health Database - Peer Reviewed Papers
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Postnatal dexamethasone: what is the real cost-benefit ratio?
Published in:
Acta Paediatr, Vol: 92, Page: 888-9
Publication Date:
August 2003
Aims & Objectives:
This paper discusses postnatal corticosteroids given early after birth reduce the risk of chronic lung disease in preterm infants but are associated with an approximate doubling of the risk of adverse neurosensory outcomes
Abstract:
Postnatal corticosteroids given early after birth reduce the risk of chronic lung disease in preterm infants but are associated with an approximate doubling of the risk of adverse neurosensory outcomes. Corticosteroids given after 7-10 d of age appear not to have these increased risks of neurosensory sequelae and reduce time on the ventilator. CONCLUSION: Further research is needed to determine the lowest dose of corticosteroid that will improve lung function and minimize risks to the developing brain.
Authors:
H. L. Halliday
Study Type:
Non Study Papers » Discussion paper, review, commentary, letter »
Keywords:
- Brain/drug effects
- Cost-Benefit Analysis
- Dexamethasone/adverse effects/economics/ therapeutic use
- Humans
- Infant, Newborn
- Infant, Premature
- Lung Diseases/ drug therapy
- Nervous System Diseases/ chemically induced
- Randomized Controlled Trials as Topic
Geography:
Northern Ireland (Northern Ireland)