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Irish Child Health Database - Peer Reviewed Papers

Database Search

• Limitations to carbon 13-labeled urea breath testing for Helicobacter pylori in infants

  Published in:

  J Pediatr, Vol: 139, Page: 734-7

  Publication Date:

  November 2001

  Aims & Objectives:

  This study examined the limitations to carbon 13-labeled urea breath testing for Helicobacter pylori in infants

  Abstract:

  We determined the validity of the carbon 13-labeled urea breath test in young children. We found that although the 13C-labeled urea breath test had a specificity greater than 90%, borderline or false positive results occurred more frequently in children younger than 2 years compared with older children. False positive results may be caused by oral-urease-producing organisms because direct intragastric administration of 13C urea reduced the excess delta 13CO2. Care is urged in interpreting one positive 13C-labeled urea breath test in children younger than 2 years.

  Authors:

  C. Imrie; M. Rowland; B. Bourke; B. Drumm

  Study Type:

  Study Papers » A study of sensitivity and specificity of a measurement tool » Descriptive Studies - Studies with a health technology dimension

  Categories:

  carbon 13-labeled urea breath; Helicobacter pylori

  International Classification:

  Diagnostic tool laboratory (urea breath test) - Helicobacter pylori

  Keywords:

  • Breath Tests
  • Carbon Isotopes/diagnostic use
  • Helicobacter Infections/ diagnosis
  • Helicobacter pylori
  • Humans
  • Infant
  • Sensitivity and Specificity

  
  

  Geography:

  Republic of Ireland (Ireland)