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Cadaveric kidney transplantation in children < or =20 kg in weight: long-term single-center experience
Published in:
Transplant Proc, Vol: 37, Page: 685-6
Publication Date:
March 2005
Aims & Objectives:
This study aimed to reported the long-term follow up from cadaveric kidney transplantation in children < or =20 kg in weight
Abstract:
BACKGROUND: We report long-term follow-up data on cadaveric kidney transplantation in children < or =20 kg in weight. METHODS: Between January 1990 and October 2003, we performed 19 cadaveric renal transplants in 19 children < or =20 kg in weight. Mean age at transplantation was 4.7 years (range 18 months to 9 years). Mean weight at transplantation was 14.4 kg (range 9 to 20 kg). Nine patients had preemptive kidney transplantation, whereas 10 were maintained on renal replacement therapy before the transplant operation. RESULTS: Actuarial 1-, 3-, 5-, and 10-year patient survival rates were 89.5%, 89.5%, 89.5%, and 82%, respectively. Actuarial 1-, 3-, 5-, and 10-year graft survival rates were 79%, 73%, 73%, 65%, respectively. Three patients died. Eight grafts failed. Cause of graft failure was death with a functioning graft in 3 patients, chronic rejection in 1, acute cellular rejection in 1, vascular rejection in 1, hemolytic-uremic syndrome in 1, and unknown in 1. CONCLUSIONS: Our results indicate the success of cadaveric kidney transplantation in the very small child with results comparable to living related donor transplantation.
Authors:
Study Type:
Study Papers » Case Series Study » Descriptive Studies - Without a comparision
Categories:
cadaveric kidney transplantation
International Classification:
Organ transplants - cadaveric
Keywords:
- Body Weight
- Cadaver
- Child
- Child, Preschool
- Follow-Up Studies
- Graft Survival/ physiology
- Humans
- Infant
- Kidney Transplantation/mortality/ physiology
- Retrospective Studies
- Survival Rate
- Tissue Donors
Geography:
Republic of Ireland (Dublin)