Accessibility
Legal Notices
Text Version

Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Child, Preschool

Your search returns 731 documents

Page:
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |

• 1.   Minimally invasive video-assisted thyroidectomy: indications and technique

  This study examined minimally invasive video-assisted thyroidectomy

  

  International Classification:

  Procedure - video-assisted thyroidectomy

  Categories:

  video-assisted thyroidectomy

  Geography:

  Republic of Ireland

  Laryngoscope, Vol: 116 Page: 1046-9 June 2006
  C. Timon; I. S. Miller

  [Preview] [Read]

• 2.   Mitral valve reconstruction in a pediatric population: late clinical results and predictors of long-term outcome

  This study reviewed 18 years of experience to establish the long-term outcomes of pediatric mitral repair

  

  Abstract:

  OBJECTIVE: Pediatric mitral valve anomalies present complex management challenges to the surgeon, who may have to choose between valve replacement or repair. We review our 18 years of experience to establish the long-term outcomes of pediatric mitral repair. METHODS: Forty-five children (22 boys) with mitral valve anomalies were studied. Mitral reconstruction was performed in all cases more...

  International Classification:

  Procedure - pediatric mitral repair

  Categories:

  pediatric mitral repair

  Geography:

  Republic of Ireland

  J Thorac Cardiovasc Surg, Vol: 130 Page: 66-73 July 2005
  A. E. Wood; D. G. Healy; L. Nolke; D. Duff; P. Oslizlok; K. Walsh

  [Preview] [Read]

• 3.   MMR/autism link rejected

  This article discusses rejection of the MMR/Autism link

  

  Abstract:

  New research has placed yet more doubt over any link between the MMr vaccine and autism. Tara Horan reports. more...

  Geography:

  Republic of Ireland

  World of Irish Nursing, Vol: 12 Page: 39-39 2004
  T. Horan

  [Preview] [Read]

• 4.   Mobility in Hurler syndrome

  This study examined the follow-up of 23 patients with Hurler syndrome at a mean of 8.5 years after successful hematopoietic stem cell transplant

  

  Abstract:

  Hurler syndrome is an autosomal recessive metabolic storage disease. Hematopoietic stem cell transplant increases life expectancy, but the effects on associated musculoskeletal abnormalities remains unclear, and long-term data are limited. We detail the follow-up of 23 patients at a mean of 8.5 years after successful hematopoietic stem cell transplant.All patients underwent clinical more...

  International Classification:

  Syndrome - Hurler

  Categories:

  Hurler syndrome

  Geography:

  Republic of Ireland

  J Pediatr Orthop, Vol: 28 Page: 163-8 March 2008
  C. Taylor; P. Brady; A. O'Meara; D. Moore; F. Dowling; E. Fogarty

  [Preview] [Read]

• 5.   Modelling the impact of antibiotic use and infection control practices on the incidence of hospital-acquired methicillin-resistant Staphylococcus aureus: a time-series analysis

  The objective of this study was to evaluate the effect of antimicrobial drug use and infection control practices on nosocomial MRSA incidence in a 426-bed general teaching hospital

  

  Abstract:

  OBJECTIVES: Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen worldwide. A wide range of factors have been suggested to influence the spread of MRSA. The objective of this study was to evaluate the effect of antimicrobial drug use and infection control practices on nosocomial MRSA incidence in a 426-bed general teaching hospital in Northern Ireland. more...

  International Classification:

  Effectiveness of measurement tool - effect of antimicrobial drug use and infection control practices on nosocomial MRSA

  Categories:

  to evaluate the effect of antimicrobial drug use and infection control practices; MRSA

  Geography:

  Northern Ireland

  J Antimicrob Chemother, Vol: 62 Page: 593-600 September 2008
  M. A. Aldeyab; D. L. Monnet; J. M. Lopez-Lozano; C. M. Hughes; M. G. Scott; M. P. Kearney; F. A. Magee; J. C. McElnay

  [Preview] [Read]

• 6.   Molecular characterization of rotavirus in Ireland: detection of novel strains circulating in the population

  The aim of this study was to examine the molecular characterization of rotavirus in Ireland: and the detection of novel strains circulating in the population

  

  Abstract:

  A collection of three hundred thirty rotavirus-positive stool samples from children with diarrhea in the southern and eastern regions of Ireland between 1997 and 1999 were submitted to the Molecular Diagnostics Unit of the Cork Institute of Technology, Cork, Ireland, for investigation. These strains were characterized by several methods, including polyacrylamide gel electropherotyping more...

  International Classification:

  International committee on Taxonomy of Viruses - rotavirus

  Categories:

  rotavirus

  Geography:

  Republic of Ireland

  J Clin Microbiol, Vol: 38 Page: 3370-4 September 2000
  F. O'Halloran; M. Lynch; B. Cryan; H. O'Shea; S. Fanning

  [Preview] [Read]

• 7.   Molecular genotyping of human cryptosporidiosis in Northern Ireland: epidemiological aspects and review

  The aim of this study was to examine the genotype of C. parvum oocysts isolated from human faeces in sporadic cases of cryptosporidiosis in Northern Ireland

  

  Abstract:

  BACKGROUND: Cryptosporidium parvum is the most common of the protozoal pathogens associated with gastrointestinal disease in Northern Ireland. Genotyping techniques are valuable in helping to elucidate sources and modes of transmission of this parasite. There have been no reports on the prevalence of genotypes in Northern Ireland, mainly due to a lack of discriminatory genotyping more...

  International Classification:

  Certain infectious and parasitic diseases - Intestinal infectious diseases - cryptosporidiosis

  Categories:

  cryptosporidiosis

  Geography:

  Northern Ireland

  Ir J Med Sci, Vol: 170 Page: 246-50 2001 Oct-Dec
  C. J. Lowery; B. C. Millar; J. E. Moore; J. Xu; L. Xiao; P. J. Rooney; L. Crothers; J. S. Dooley

  [Preview] [Read]

• 8.   Morbidity and mortality following inadvertent poisoning with decanted chemicals

  The aim of this study was to examine the epidemiology of accidental poisoning with decanted chemicals

  

  Abstract:

  Decanting of chemicals from their original containers is a hazardous practice that can result in inadvertent poisoning. We conducted a four-year prospective observational study to analyse the epidemiology of accidental poisoning with decanted chemicals. 157 patients were poisoned following accidental exposure to chemicals transferred to innocuous containers. 106 patients attended more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - poisoning

  Categories:

  accidental poisoning

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 98 Page: 175-8 June 2005
  N. Cassidy; J. A. Tracey

  [Preview] [Read]

• 9.   Morbidity, mortality, and response to treatment by children in the United Kingdom and Ireland with perinatally acquired HIV infection during 1996-2006: planning for teenage and adult care

  The aim of this study was to examine temporal changes in the morbidity and mortality persons with perinatally acquired HIV infection, many of whom are now adolescents.

  

  Abstract:

  BACKGROUND: Recent evidence suggests that decreases in morbidity and mortality in cohorts of adults infected with human immunodeficiency virus (HIV) are showing signs of reversal. We describe changes over time in these characteristics and in the response to treatment among children in the United Kingdom and Ireland with perinatally acquired HIV infection, many of whom are now more...

  International Classification:

  Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV

  Categories:

  perinatally acquired HIV infection

  Geography:

  Republic of Ireland and the United Kingdom

  Clin Infect Dis, Vol: 45 Page: 918-24 October 2007
  A. Judd; K. Doerholt; P. A. Tookey; M. Sharland; A. Riordan; E. Menson; V. Novelli; E. G. Lyall; J. Masters; G. Tudor-Williams; T. Duong; D. M. Gibb

  [Preview] [Read]

• 10.   Mortality predictions for colon and anorectal cancer for Ireland, 2003-17

  The aim of this study was to examine colorectal cancer mortality predictions for Ireland for all ages and for the age group 0-64 years.

  

  Abstract:

  OBJECTIVE: Colorectal cancer mortality predictions for Ireland are presented for all ages and for the age group 0-64 years. METHODS: Log and log-linear Poisson regression modelling was fitted to colorectal cancer mortality data for each year between 1950 and 2002 to predict average European age standardized mortality rates (EASMRs) per 100,000 person years (100,000 PY(-1)) and average more...

  International Classification:

  Deaths - colorectal cancer

  Categories:

  colorectal cancer mortality

  Geography:

  Republic of Ireland

  Colorectal Dis, Vol: 8 Page: 393-401 June 2006
  P. O'Lorcain; S. Deady; H. Comber

  [Preview] [Read]

• 11.   Mothers' dietary patterns during pregnancy and risk of asthma symptoms in children at 3 years

  This study examined maternal dietary patterns during pregnancy influenced general practitioner diagnosis of asthma by the age of 3 years in the Life-ways cohort of children.

  

  Abstract:

  There is increasing evidence that dietary factors in early life play a role in the aetiology of childhood asthma. Our objective in this analysis was to assess whether maternal dietary patterns during pregnancy, as measured by a validated food frequency questionnaire, influenced general practitioner diagnosis of asthma by the age of 3 years in the Life-ways cohort of children. General more...

  International Classification:

  Longitudinal - Maternal dietary patterns and childhood asthma

  Categories:

  maternal dietary patterns and childhood asthma

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 100 Page: suppl 27-32 September 2007
  N. Fitzsimon; U. Fallon; D. O'Mahony; B. G. Loftus; G. Bury; A. W. Murphy; C. C. Kelleher

  [Preview] [Read]

• 12.   Multifocal infantile myofibromatosis and generalized fibromuscular dysplasia in a child: evidence for a common pathologic process?

  This case report discusses a patient in whom Infantile myofibromatosis was diagnosed, on the basis of multiple soft tissue tumours present from birth, who subsequently developed generalized and ultimately fatal fibromuscular dysplasia

  

  Abstract:

  Infantile myofibromatosis (IM) is a condition characterized by the formation of spindle cell tumors of skin, soft tissue, and viscera. Although small vessel involvement by the process is a frequently identified and indeed diagnostically useful histological finding, involvement of large vessels is not widely reported. Fibromuscular dysplasia (FMD) is a noninflammatory arteriopathy more...

  International Classification:

  Diseases of the skin and subcutaneous tissue - Report

  Categories:

  Infantile myofibromatosis

  Geography:

  Republic of Ireland

  Pediatr Dev Pathol, Vol: 7 Page: 385-90 2004 Jul-Aug
  C. Wright; M. T. Corbally; R. Hayes; M. B. McDermott

  [Preview] [Read]

• 13.   Multiple sclerosis in Northern Ireland: a historical and global perspective

  The aim of this study was to examine the prevalence of multiple sclerosis in Northern Ireland

  

  Abstract:

  The uneven worldwide distribution of multiple sclerosis has been of interest to epidemiologists, neurologists and statisticians for over a century, prevalence rates for the disease apparently being determined by variations in age, gender, geography, race and ethnic group. Northern Ireland has been recognised as an area of high MS prevalence since the truly seminal work of Allison and more...

  International Classification:

  Diseases of the nervous system - Demyelinating diseases of the central nervous system - multiple sclerosis

  Categories:

  multiple sclerosis

  Geography:

  Northern Ireland

  Ulster Med J, Vol: 69 Page: 97-105 November 2000
  G. V. McDonnell; S. A. Hawkins

  [Preview] [Read]

• 14.   Multiplex PCR for identification of seven Streptococcus pneumoniae serotypes targeted by a 7-valent conjugate vaccine

  This study aimed to describe Streptococcus pneumoniae one-step multiplex PCR assay which identifies by amplicon size the seven capsular polysaccharide serotypes targeted by the 7-valent conjugate vaccine

  

  Abstract:

  Here we describe a Streptococcus pneumoniae one-step multiplex PCR assay which identifies by amplicon size the seven capsular polysaccharide serotypes targeted by the 7-valent conjugate vaccine. The multiplex PCR assay was used to blindly assay clinical isolates recovered during 1999 in the Republic of Ireland from cases of invasive disease whose serotypes were previously determined by more...

  International Classification:

  Effectiveness of measurement tool - one-step multiplex PCR assay

  Categories:

  one-step multiplex PCR assay; Streptococcus pneumoniae

  Geography:

  Republic of Ireland

  J Clin Microbiol, Vol: 43 Page: 3487-90 July 2005
  M. O'Halloran D; M. T. Cafferkey

  [Preview] [Read]

• 15.   Mumps in Ireland, 2004-2008

  This study discusses the occurrence of mumps in Ireland 2004-2008

  

  International Classification:

  Surveillance - Certain infectious and parasitic diseases - Other viral diseases - mumps

  Categories:

  mumps

  Geography:

  Republic of Ireland

  Euro Surveill, Vol: 13 Page: April 2008
  S. Gee; D. O'Flanagan; M. Fitzgerald; S. Cotter

  [Preview] [Read]

• 16.   Mumps outbreak among young people in Northern Ireland

  The aim of this study was to describe outbreak of mumps in the Mid-Ulster area of Northern Ireland between 1st November 1999 and 31st August 2000

  

  Abstract:

  An outbreak of mumps occurred in the Mid-Ulster area of Northern Ireland between 1st November 1999 and 31st August 2000, with 729 cases notified. Salivary test results were obtained for 430 (59%) reported cases, of which 332 (77%) were positive for mumps IgM antibody. Three hundred and sixteen (95.2%) of these confirmed cases were in the age range 9 to 19. One hundred and eighty-four more...

  International Classification:

  Certain infectious and parastic diseases - Other viral diseases - mumps

  Categories:

  mumps

  Geography:

  Northern Ireland

  Commun Dis Public Health, Vol: 4 Page: 311-5 December 2001
  E. A. Reaney; V. K. Tohani; M. J. Devine; R. D. Smithson; B. Smyth

  [Preview] [Read]

• 17.   Muscarinic acetylcholine receptor expression in aganglionic bowel

  The aim of this study was to examine the expression of each mAChR subtype in aganglionic colon to further understand the pathophysiology of Hirschsprung's disease

  

  Abstract:

  In Hirschsprung's disease (HD) there exists an overabundance of acetylcholine (ACh), which in turn stimulates excessive production of the enzyme acetylcholinesterase. Muscarinic ACh receptors (mAChRs) play an important role in smooth-muscle contraction. Recent studies have indicated five different subtypes of mAChRs encoded by five different genes, ml to m5. The purpose of this study more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease

  Categories:

  expression of mAChR subtypes; Hirschsprung's disease

  Geography:

  Republic of Ireland

  Pediatr Surg Int, Vol: 16 Page: 267-71 2000
  T. Oue; A. Yoneda; H. Shima; P. Puri

  [Preview] [Read]

• 18.   Nasal foreign bodies in children: should they have a plain radiograph in the accident and emergency?

  This study examined the proportion of children with nasal foreign bodies who had button batteries as the foreign body

  

  Abstract:

  OBJECTIVES: Primary Objective: To determine the proportion of children with nasal foreign bodies who had button batteries as the foreign body. SECONDARY OBJECTIVE: To describe the clinical care and outcome of those children with a button battery foreign body. METHODS: A retrospective review of all children presenting to the accident and emergency room with a nasal foreign body or more...

  International Classification:

  Other - nasal foreign bodies

  Categories:

  nasal foreign bodies

  Geography:

  Republic of Ireland

  Pediatr Emerg Care, Vol: 24 Page: 217-8 April 2008
  F. Glynn; M. Amin; J. Kinsella

  [Preview] [Read]

• 19.   Nasalance scores for normal-speaking Irish children

  The aim of this study was to describe normal nasalance values during the production of a standardized speech sample for Irish children and determine whether significantly different scores exist for different speech stimuli for female and male speakers

  

  Abstract:

  OBJECTIVE: To obtain normal nasalance values during the production of a standardized speech sample for Irish children and determine whether significantly different scores exist for different speech stimuli for female and male speakers. DESIGN: Mean nasalance scores were obtained for normal-speaking children during the repetition of 16 test sentences that were categorized according to more...

  International Classification:

  Language

  Categories:

  standardized speech

  Geography:

  Republic of Ireland

  Cleft Palate Craniofac J, Vol: 41 Page: 168-74 March 2004
  T. Sweeney; D. Sell; M. O'Regan

  [Preview] [Read]

• 20.   National enhanced surveillance of meningococcal disease in England, Wales and Northern Ireland, January 1999-June 2001

  The aim of this study was to examine the incidence meningococcal disease and the enhanced surveillance of meningococcal disease (ESMD) which was implemented nationally across ten regions of England, Wales and Northern Ireland from 1 January 1999.

  

  Abstract:

  Enhanced surveillance of meningococcal disease (ESMD) was implemented nationally across ten regions of England, Wales and Northern Ireland from 1 January 1999. It aims to deliver more sensitive surveillance than laboratory reporting by including clinically diagnosed but laboratory unconfirmed cases. Consultants in Communicable Disease Control (CsCDC) report all clinically diagnosed more...

  International Classification:

  Certain infectious and parasitic diseases - Other bacterial diseases - meningococcal disease

  Categories:

  meningococcal disease

  Geography:

  the United Kingdom

  Epidemiol Infect, Vol: 129 Page: 459-70 December 2002
  M. Shigematsu; K. L. Davison; A. Charlett; N. S. Crowcroft

  [Preview] [Read]

• 21.   Neuroimaging findings in glutaric aciduria type 1

  This study reviewed the imaging features of glutaric aciduria type 1, and to document the findings not previously reported and compare our findings with the imaging characteristics of GA-1 previously reported

  

  Abstract:

  OBJECTIVE: To review the imaging features of glutaric aciduria type 1 (GA-1) in a group of 20 patients, the largest published series to date. To document the findings not previously reported and compare our findings with the imaging characteristics of GA-1 previously reported in the literature. MATERIALS AND METHODS: For 14 patients the original scans were examined and in the remaining more...

  International Classification:

  Diseases of the digestive system - Diseases of appendix - appendicoliths

  Categories:

  glutaric aciduria type 1

  Geography:

  Republic of Ireland

  Pediatr Radiol, Vol: 33 Page: 823-30 December 2003
  E. L. Twomey; E. R. Naughten; V. B. Donoghue; S. Ryan

  [Preview] [Read]

• 22.   New contralateral vesicoureteral reflux after endoscopic correction of unilateral reflux--is routine contralateral injection indicated at initial treatment?

  This study examined the incidence of newly diagnosed contralateral reflux after endoscopic correction of unilateral reflux and identified possible risk factors for its development

  

  Abstract:

  PURPOSE: As more and more pediatric urologists use endoscopic therapy as a primary treatment option for vesicoureteral reflux, newer indications for this procedure are being considered. Recently it was suggested that contralateral nonrefluxing ureters should be treated prophylactically in patients undergoing unilateral endoscopic correction of vesicoureteral reflux. We analyzed the more...

  International Classification:

  Procedure - endoscopic correction and contralateral reflux

  Categories:

  contralateral reflux

  Geography:

  Republic of Ireland

  J Urol, Vol: 178 Page: 1711-3 October 2007
  M. Menezes; N. Mohanan; J. Haroun; E. Colhoun; P. Puri

  [Preview] [Read]

• 23.   New cross sectional stature, weight, and head circumference references for Down's syndrome in the UK and Republic of Ireland

  The aim of this study was to develop a growth reference chart for children with uncomplicated down syndrome in the United Kingdom and Ireland

  

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Chromosomal abnormalities, not elsewhere classified - Down Syndrome

  Categories:

  growth reference chart

  Geography:

  Republic of Ireland and the United Kingdom

  Archives of Disease in Childhood, Vol: 87 Page: 104-108 2002
  M. E. Styles; T. J. Cole; J. Dennis; M. A. Preece

  [Preview] [Read]

• 24.   New technique for fixation of Broviac catheters

  This article discusses a technique in which an internal fixation suture is placed to prevent dislodgement or migration of Broviac catheters

  

  Abstract:

  Broviac catheters are in common use for administration of parenteral nutrition, cancer chemotherapy, and antibiotic therapy within the paediatric population. Inadvertent dislodgement of these catheters is common during the initial weeks before the Dacron cuff is anchored by the ingrowth of fibrous tissue. The authors describe a technique in which an internal fixation suture is placed to more...

  Geography:

  Republic of Ireland

  J Pediatr Surg, Vol: 38 Page: 51-2 January 2003
  T. Sri Paran; M. Corbally; R. I. Fitzgerald

  [Preview] [Read]

• 25.   News

  News: Preschool children

  

  Geography:

  Republic of Ireland

  Focus on Alternative & Complementary Therapies, Vol: 12 Page: 137-138 2007

  [Preview] [Read]

• 26.   Nicotinic acetylcholine receptor alpha4 subunit gene polymorphism and attention deficit hyperactivity disorder

  The aim of this study was to examine examined the alpha 4 receptor, one of the sites of action of ABT-418 to examine the effect of nicotine in families with ADHD

  

  Abstract:

  Attention deficit hyperactivity disorder (ADHD) is a highly heritable, common psychiatric disorder that presents in childhood and that probably involves several genes. There are several lines of evidence suggesting that the nicotinic system may be functionally significant in ADHD: (a) nicotine promotes the release of dopamine and has been shown to improve attention in adults with ADHD, more...

  International Classification:

  Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder

  Categories:

  attention-deficit hyperactivity disorder

  Geography:

  Republic of Ireland and the United Kingdom

  Psychiatr Genet, Vol: 11 Page: 37-40 March 2001
  L. Kent; F. Middle; Z. Hawi; M. Fitzgerald; M. Gill; C. Feehan; N. Craddock

  [Preview] [Read]

• 27.   Nitrergic hyperinnervation in appendicitis and in appendices histologically classified as normal

  The aim of this study was to examine the nitrergic innervation of (a) inflamed appendices (b) appendices classified as histologically normal from patients with a clinical diagnosis of appendicitis (c) normal control appendix specimens

  

  Abstract:

  CONTEXT: The pathogenesis of appendicitis remains poorly understood. Despite new diagnostic techniques, appendices removed from patients with suspected appendicitis often appear histologically normal on conventional examination. There is increasing evidence of involvement of the enteric nervous system in immune regulation and in inflammatory responses in the gastrointestinal system. more...

  International Classification:

  Diseases of the digestive system - Diseases of appendix - appendixes

  Categories:

  nitrergic innervation; appendix

  Geography:

  Republic of Ireland

  Arch Pathol Lab Med, Vol: 127 Page: 573-8 May 2003
  L. Nemeth; U. Rolle; D. J. Reen; P. Puri

  [Preview] [Read]

• 28.   Nitric oxide, enhanced by macrophage-colony stimulating factor, mediates renal damage in reflux nephropathy

  The aim of this study was to investigate the expression of inducible nitric oxide synthase (iNOS) and M-CSF in the refluxing kidney, in order to further understand the pathogenesis of reflux nephropathy

  

  Abstract:

  BACKGROUND: Reflux nephropathy (RN) is a major cause of end-stage renal failure in children and young adults. Nitric oxide (NO) is an important mediator of tissue injury and inflammation. NO production is enhanced by hematopoietic growth factor including macrophage colony stimulating factor (M-CSF). M-CSF plays a pivotal role in the development of nephritis via macrophage activation. more...

  International Classification:

  Diseases of the genitourinary system - reflux nephropathy

  Categories:

  nitric oxide synthase; -reflux nephropathy

  Geography:

  Republic of Ireland

  Kidney Int, Vol: 62 Page: 507-13 August 2002
  U. Rolle; H. Shima; P. Puri

  [Preview] [Read]

• 29.   No association between catechol-O-methyltransferase (COMT) gene polymorphism and attention deficit hyperactivity disorder (ADHD) in an Irish sample

  The aim of this study was to examine the association between catechol-O-methyltransferase gene polymorphism and attention deficit hyperactivity disorder in an Irish sample

  

  Abstract:

  Pharmacological and biochemical studies have indicated that imbalances in dopaminergic transmission may contribute to the aetiology of attention deficit hyperactivity disorder (ADHD). The enzyme catechol-O-methyltransferase (COMT) plays a key role in the degradation of catecholamines such as dopamine, L-DOPA, adrenaline, and noradrenaline and therefore could be considered as a candidate more...

  International Classification:

  Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder

  Categories:

  attention-deficit hyperactivity disorder

  Geography:

  Republic of Ireland

  Am J Med Genet, Vol: 96 Page: 282-4 June 2000
  Z. Hawi; N. Millar; G. Daly; M. Fitzgerald; M. Gill

  [Preview] [Read]

• 30.   No association between TPH2 gene polymorphisms and ADHD in a UK sample

  The aim of this study was to examine four single nucleotide polymorphisms two of which (rs1843809, rs1386493) were reported to associate with attention-deficit hyperactivity disorder

  

  Abstract:

  Tryptophan Hydroxylase 2 (TPH2) is the rate-limiting enzyme in the biosynthesis of serotonin which is exclusively expressed in the brain. Recent molecular studies reported significant association between markers mapped to TPH2 and psychiatric conditions including ADHD. We have examined four single nucleotide polymorphisms (SNPs) two of which (rs1843809, rs1386493) were reported to more...

  International Classification:

  Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder

  Categories:

  attention-deficit hyperactivity disorder

  Geography:

  Republic of Ireland

  Neurosci Lett, Vol: 412 Page: 105-7 January 2007
  K. Sheehan; Z. Hawi; M. Gill; L. Kent

  [Preview] [Read]

• 31.   No association of the dopamine DRD4 receptor (DRD4) gene polymorphism with attention deficit hyperactivity disorder (ADHD) in the Irish population

  The aim of this study was to examine the association of the dopamine DRD4 receptor gene polymorphism with attention deficit hyperactivity disorder in the Irish population

  

  Abstract:

  Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent childhood-onset syndromes affecting 3%-6% of school-age children worldwide. Although the biological basis of ADHD is unknown, a dopaminergic abnormality has long been suggested. The dopamine D4 receptor gene (DRD4) has been mapped to chromosome 11p15.5 and has been implicated in predisposition to ADHD. Several more...

  International Classification:

  Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder

  Categories:

  attention deficit hyperactivity disorder

  Geography:

  Republic of Ireland

  Am J Med Genet, Vol: 96 Page: 268-72 June 2000
  Z. Hawi; M. McCarron; A. Kirley; G. Daly; M. Fitzgerald; M. Gill

  [Preview] [Read]

• 32.   Non-bronchoscopic sampling and culture of bronchial epithelial cells in children

  The aim of this study was to examine the possibility of retrieving and culturing viable epithelial cells using a blind non-bronchoscopic method from children undergoing elective surgery

  

  Abstract:

  BACKGROUND: The bronchial epithelium is likely to play a vital role in airway diseases in children, such as asthma and viral-associated wheeze. In adults, studies with primary bronchial epithelial cells cultured from samples obtained by fibre-optic bronchoscopy have provided key insights into the role of the epithelial cell. However, it is difficult to justify bronchoscopy in children more...

  International Classification:

  Health service provision

  Categories:

  elective surgery

  Geography:

  Northern Ireland

  Clin Exp Allergy, Vol: 33 Page: 1221-5 September 2003
  G. M. Doherty; S. N. Christie; G. Skibinski; S. M. Puddicombe; T. J. Warke; F. de Courcey; A. L. Cross; J. D. Lyons; M. Ennis; M. D. Shields; L. G. Heaney

  [Preview] [Read]

• 33.   Noncatheter-based delivery of a single-chamber lumenless pacing lead in small children

  This study described the noncatheter-based delivery of a single-chamber lumenless pacing lead in small children

  

  Abstract:

  OBJECTIVES: The model 3830 lead (SelectSecure Medtronic, Minneapolis, MN, USA) is a bipolar, fixed-screw, 4.1-F pacing lead designed for site-selective pacing. Implantation is usually performed using an 8-F deflectable catheter system. This catheter is not ideal for smaller children because of both the sheath size and the relatively large deflected curves. We describe a simpler more...

  International Classification:

  Procedure - pacing lead

  Categories:

  noncatheter-based delivery of a single-chamber lumenless pacing lead

  Geography:

  Republic of Ireland

  Pacing Clin Electrophysiol, Vol: 30 Page: 834-8 July 2007
  D. Kenny; K. P. Walsh

  [Preview] [Read]

• 34.   Non-orthopaedic paediatric trauma in a regional hospital

  The aim of this study was to audit staff experience with paediatric trauma in a regional setting

  

  Abstract:

  BACKGROUND: In the Republic of Ireland there are no paediatric surgeons outside Dublin. Most paediatric trauma is managed in general hospitals by general or orthopaedic surgeons. AIM: In this study we audited our experience with paediatric trauma in a regional setting. METHODS: We carried out a retrospective review of all non-orthopaedic paediatric trauma patients admitted to our more...

  International Classification:

  External causes of morbidity and mortality - unclear - trauma

  Categories:

  paediatric trauma

  Geography:

  Republic of Ireland

  Ir J Med Sci, Vol: 174 Page: 23-7 2005 Oct-Dec
  J. Shabbir; M. A. Shah; A. Nissar; M. Clarke-Moloney; E. G. Kavanagh; J. Drumm; P. A. Grace

  [Preview] [Read]

• 35.   Non-specialist paediatric surgery--where should it be performed?

  The aim of this study was to discuss where peadiatric surgery be performed

  

  International Classification:

  Procedure - peadiatric surgery

  Categories:

  peadiatric surgery

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 92 Page: 439 1999 Nov-Dec
  O. Ni Chonmide; M. McMahon; P. Gillen; F. Lennon; S. Gormally; A. Murphy; A. Nicholson

  [Preview] [Read]

• 36.   Non-susceptibility trends among Enterobacteriaceae from bacteraemias in the UK and Ireland, 2001-06

  The aim of this study was to examine non-susceptibility trends among Enterobacteriaceae from bacteraemias in the United Kingdom and Ireland, 2001-06

  

  Abstract:

  BACKGROUND: Enterobacteriaceae are common agents of bacteraemia, with Escherichia coli accounting for 20% of the cases. Reflecting this importance, members of the family constitute 4 of the 12 collection groups in the British Society for Antimicrobial Chemotherapy (BSAC) Bacteraemia Surveillance Programme. METHODS: MICs from the BSAC surveillance programme were reviewed, along with more...

  International Classification:

  Bacterium - Enterobacteriaceae

  Categories:

  Enterobacteriaceae; bacteraemias

  Geography:

  Republic of Ireland and the United Kingdom

  J Antimicrob Chemother, Vol: 62 Suppl 2 Page: ii41-54 November 2008
  D. M. Livermore; R. Hope; G. Brick; M. Lillie; R. Reynolds

  [Preview] [Read]

• 37.   Non-susceptibility trends among enterococci and non-pneumococcal streptococci from bacteraemias in the UK and Ireland, 2001-06

  The aim of this study was to examine patterns and trends in antimicrobial susceptibility in enterococci and streptococci (excepting pneumococci) from bacteraemia in the UK and Ireland from 2001 to 2006

  

  Abstract:

  OBJECTIVES: To describe the current patterns and trends in antimicrobial susceptibility in enterococci and streptococci (excepting pneumococci) from bacteraemia in the UK and Ireland from 2001 to 2006. METHODS: In each year 2001-06, blood culture isolates were collected by 25 laboratories distributed across the UK and Ireland. In total, there were 1408 isolates of enterococci, 1332 of more...

  International Classification:

  Bacterium - Enterococci and streptococci

  Categories:

  enterococci; streptococci

  Geography:

  Republic of Ireland and the United Kingdom

  J Antimicrob Chemother, Vol: 62 Suppl 2 Page: ii75-85 November 2008
  D. F. Brown; R. Hope; D. M. Livermore; G. Brick; K. Broughton; R. C. George; R. Reynolds

  [Preview] [Read]

• 38.   Non-susceptibility trends among Haemophilus influenzae and Moraxella catarrhalis from community-acquired respiratory tract infections in the UK and Ireland, 1999-2007

  The aim of this study was to examine the antimicrobial susceptibility of Haemophilus influenzae and Moraxella catarrhalis causing community-acquired respiratory tract infections in the UK and Ireland from 1999/2000 to 2006/07

  

  Abstract:

  OBJECTIVES: To determine the antimicrobial susceptibility of Haemophilus influenzae and Moraxella catarrhalis causing community-acquired respiratory tract infections in the UK and Ireland from 1999/2000 to 2006/07. METHODS: Sentinel laboratories across the UK and Ireland contributed up to a fixed quota of isolates of defined organisms per annum. A central laboratory confirmed the more...

  International Classification:

  Bacterium - Haemophilus influenzae

  Categories:

  antimicrobial susceptibility; Haemophilus influenzae; Moraxella catarrhalis

  Geography:

  Republic of Ireland and the United Kingdom

  J Antimicrob Chemother, Vol: 62 Suppl 2 Page: ii97-103 November 2008
  I. Morrissey; K. Maher; L. Williams; J. Shackcloth; D. Felmingham; R. Reynolds

  [Preview] [Read]

• 39.   Non-susceptibility trends among Pseudomonas aeruginosa and other non-fermentative Gram-negative bacteria from bacteraemias in the UK and Ireland, 2001-06

  The aim of this study was to examine non-susceptibility trends among Pseudomonas aeruginosa and other non-fermentative Gram-negative bacteria from bacteraemias in the United Kingdom and Ireland, 2001-06

  

  Abstract:

  BACKGROUND: Pseudomonas and Acinetobacter spp. are important opportunists, notorious for resistance. Pseudomonas spp. are collected in the British Society for Antimicrobial Chemotherapy (BSAC) bacteraemia surveillance, with Acinetobacter spp. and Stenotrophomonas maltophilia well represented in the 'other Gram-negatives' group. METHODS: Data for collected isolates were reviewed together more...

  International Classification:

  Bacterium - Pseudomonas aeruginosa

  Categories:

  Pseudomonas aeruginosa; non-fermentative Gram-negative bacteria; bacteraemias

  Geography:

  Republic of Ireland and the United Kingdom

  J Antimicrob Chemother, Vol: 62 Suppl 2 Page: ii55-63 November 2008
  D. M. Livermore; R. Hope; G. Brick; M. Lillie; R. Reynolds

  [Preview] [Read]

• 40.   Non-susceptibility trends among staphylococci from bacteraemias in the UK and Ireland, 2001-06

  The aim of this study was to examine non-susceptibility trends among staphylococci from bacteraemias in the United Kingdom and Ireland, 2001-06

  

  Abstract:

  OBJECTIVES: Investigation of the antibiotic susceptibilities and trends for staphylococci collected from bacteraemia cases in the UK and Ireland, from 2001 to 2006, as part of the British Society for Antimicrobial Chemotherapy's Bacteraemia Surveillance Programme. METHODS: Twenty-five hospitals from the UK and Ireland each collected up to 10 consecutive isolates of both Staphylococcus more...

  International Classification:

  Bacterium - Staphylococci

  Categories:

  staphylococci

  Geography:

  Republic of Ireland and the United Kingdom

  J Antimicrob Chemother, Vol: 62 Suppl 2 Page: ii65-74 November 2008
  R. Hope; D. M. Livermore; G. Brick; M. Lillie; R. Reynolds

  [Preview] [Read]

• 41.   Non-susceptibility trends and serotype distributions among Streptococcus pneumoniae from community-acquired respiratory tract infections and from bacteraemias in the UK and Ireland, 1999 to 2007

  The aim of this study was to examine non-susceptibility trends and serotype distributions among Streptococcus pneumoniae from community-acquired respiratory tract infections and from bacteraemias in the United Kingdom and Ireland, 1999 to 2007

  

  Abstract:

  OBJECTIVES: Pneumococcal disease is prevalent and is a cause of significant morbidity and mortality in the UK and Ireland. We describe the antimicrobial susceptibility and serotype distributions of Streptococcus pneumoniae causing bacteraemia and community-acquired pneumonia in these countries from 1999/2000 to 2006/7, predominantly prior to the introduction of the heptavalent more...

  International Classification:

  Bacterium - Streptococcus pneumoniae

  Categories:

  Streptococcus pneumoniae; community-acquired respiratory tract infections

  Geography:

  Republic of Ireland and the United Kingdom

  J Antimicrob Chemother, Vol: 62 Suppl 2 Page: ii87-95 November 2008
  D. J. Farrell; D. Felmingham; J. Shackcloth; L. Williams; K. Maher; R. Hope; D. M. Livermore; R. C. George; G. Brick; S. Martin; R. Reynolds

  [Preview] [Read]

• 42.   Non-syndromic trigonocephaly: surgical decision making and long-term cosmetic results

  This study examined the long-term aesthetic outcome of cosmetic correction of trigonocephaly

  

  Abstract:

  BACKGROUND: Surgical correction is often required for cosmetic correction of trigonocephaly. The purpose of this paper was to report the long-term aesthetic outcome as appreciated by the parents/patients themselves. The self-evaluation of cosmetic outcome after trigonocephaly correction has not previously been reported. The management and different surgical techniques utilized over a more...

  International Classification:

  Procedure - trigonocephaly

  Categories:

  trigonocephaly

  Geography:

  Republic of Ireland

  Childs Nerv Syst, Vol: 23 Page: 1285-9 November 2007
  M. O. Kelleher; D. J. Murray; A. McGillivary; M. H. Kamel; D. Allcutt; M. J. Earley

  [Preview] [Read]

• 43.   Non-traumatic brachial plexopathies, clinical, radiological and neurophysiological findings from a tertiary centre

  This study examined the clinical characteristics, aetiology, neuro-physiological characteristics, imaging findings and other investigations in a cohort of patients with non-traumatic brachial plexopathy

  

  Abstract:

  OBJECTIVE: To establish the clinical characteristics, aetiology, neuro-physiological characteristics, imaging findings and other investigations in a cohort of patients with non-traumatic brachial plexopathy (BP). METHODS: A 3-year retrospective study of patients with non-traumatic BP identified by electromyography (EMG) and nerve conduction studies (NCS). Clinical information was more...

  International Classification:

  Diseases of the nervous system - Nerve, nerve root and plexus disorders - non-traumatic brachial plexopathy

  Categories:

  non-traumatic brachial plexopathy

  Geography:

  Republic of Ireland

  Clin Neurol Neurosurg, Vol: 109 Page: 661-6 October 2007
  G. M. Mullins; S. S. O'Sullivan; A. Neligan; S. Daly; R. J. Galvin; B. J. Sweeney; B. McNamara

  [Preview] [Read]

• 44.   Non-type b Haemophilus influenzae disease: clinical and epidemiologic characteristics in the Haemophilus influenzae type b vaccine era

  The aim of this study was to describe the clinical and epidemiologic features of non-b Hi disease

  

  Abstract:

  BACKGROUND: As a result of the decline in Haemophilus influenzae type b (Hib) disease caused by the widespread use of conjugate vaccines, non-type b H. influenzae will become a more important cause of H. influenzae (Hi) disease. Characterization of the clinical and epidemiologic features of non-b Hi disease is needed in the Hib vaccine era. METHODS: A prospective active surveillance more...

  International Classification:

  Other - non-b Haemophilus influenzae disease

  Categories:

  non-b Hi disease

  Geography:

  Republic of Ireland and the United Kingdom

  Pediatr Infect Dis J, Vol: 20 Page: 300-5 March 2001
  P. T. Heath; R. Booy; H. J. Azzopardi; M. P. Slack; J. Fogarty; A. C. Moloney; M. E. Ramsay; E. R. Moxon

  [Preview] [Read]

• 45.   Normal variants in the paediatric orthopaedic population

  This study examined normal variants in the paediatric orthopaedic population

  

  Abstract:

  Normal variations of lower limb development are a common source of parental concern and are commonly referred to paediatric orthopaedic clinics. To determine the proportion of children referred to a paediatric orthopaedic outpatients with potentially normal developmental variations, referral letters and case notes of children attending the paediatric orthopaedic clinic at our more...

  International Classification:

  Other - variants in the paediatric orthopaedic population

  Categories:

  variants in the paediatric orthopaedic population

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 99 Page: 13-4 January 2006
  D. Molony; G. Hefferman; M. Dodds; D. McCormack

  [Preview] [Read]

• 46.   Norovirus outbreak associated with a hotel in the west of Ireland, 2006

  This study reports a norovirus outbreak associated in a hotel in the west of Ireland in 2006

  

  Abstract:

  An outbreak of gastrointestinal disease (nausea, vomiting or diarrhoea) occurred among a party of wedding guests, staff and other guests in a hotel in the west of Ireland, in October 2006. Upon notification, a multi-disciplinary outbreak control team was convened to investigate and control the outbreak. In all, 98 people were ascertained ill. The median duration of illness was 48 hours. more...

  International Classification:

  Surveillance - International committee on Taxonomy of Viruses - norovirus

  Categories:

  norovirus

  Geography:

  Republic of Ireland

  Euro Surveill, Vol: 12 Page: E11-2 July 2007
  A. Michel; R. Fitzgerald; D. Whyte; A. Fitzgerald; E. Beggan; N. O'Connell; T. Greally

  [Preview] [Read]

• 47.   Northern Ireland

  Legal notes. Northern Ireland - 2003 - Subjects: Child Abuse; Child Welfare

  

  Categories:

  child abuse; Child Welfare

  Geography:

  Northern Ireland

  Adoption & Fostering, Vol: 27 Page: 70-72 2003
  K. O'Halloran

  [Preview] [Read]

• 48.   Northern Ireland

  Legal notes. Northern Ireland - 2006 - Subjects: Adoption; Child Welfare; Preschool Children

  

  Categories:

  adoption; Child Welfare

  Geography:

  Northern Ireland

  Adoption & Fostering, Vol: 30 Page: 72-76 2006
  K. O'Halloran

  [Preview] [Read]

• 49.   Ocular findings among patients with late-diagnosed or poorly controlled homocystinuria compared with a screened, well-controlled population

  The aim of this study was to examine ocular features in utreated homocystinuria patients who had late diagnosis or were noncompliant with treatment compared with a control group of early-diagnosed and well-controlled subjects.

  

  Abstract:

  INTRODUCTION: Untreated homocystinuria (HCU) leads to systemic and ocular complications preventable by early treatment. METHODS: This study describes the ocular features in HCU patients who had late diagnosis or were noncompliant with treatment compared with a control group of early-diagnosed and well-controlled subjects. RESULTS: Fourteen late-diagnosed HCU patients with a median age more...

  International Classification:

  Endocrine, nutritional and metabolic diseases - Metabolic disorders - homocystinuria

  Categories:

  timing of diagnosis; -homocystinuria;

  Geography:

  Republic of Ireland

  J Aapos, Vol: 5 Page: 311-5 October 2001
  A. Mulvihill; S. Yap; M. O'Keefe; P. M. Howard; E. R. Naughten

  [Preview] [Read]

• 50.   Ocular findings in glutaric aciduria type 1

  This study determines the nature and course of ocular abnormalities in glutaric aciduria (acidemia) type 1 (GA1).

  

  Abstract:

  PURPOSE: To determine the nature and course of ocular abnormalities in glutaric aciduria (acidemia) type 1 (GA1). METHODS: Fifteen children with GA1 have been studied in the Republic of Ireland. A retrospective review of the records of the 6 children who died during their illness and prospective clinical examination of 9 survivors were performed. RESULTS: Seven of the 15 children had more...

  International Classification:

  Endocrine, nutritional and metabolic diseases - Metabolic disorders - glutaric aciduria type 1

  Categories:

  ocular abnormalities in glutaric aciduria

  Geography:

  Republic of Ireland

  J Pediatr Ophthalmol Strabismus, Vol: 37 Page: 289-93 2000 Sep-Oct
  N. A. Kafil-Hussain; A. Monavari; R. Bowell; P. Thornton; E. Naughten; M. O'Keefe

  [Preview] [Read]

• 51.   Ocular toxocariasis in schoolchildren

  The aim of this study was to examine the extent of consultant-diagnosed toxocaral eye disease among a population of schoolchildren

  

  Abstract:

  Ocular toxocariasis in humans is typically a unilateral disease caused by second-stage larvae of the Toxocara species. Serological evidence of widespread infection in humans provides little information on clinical disease. There is only a single previous estimate of the prevalence of ocular toxocariasis (from Alabama). The present survey examined the extent of consultant-diagnosed more...

  International Classification:

  Certain infectious and parasitic diseases - Helminthiases - toxocaral eye disease

  Categories:

  consultant-diagnosed toxocaral eye disease

  Geography:

  Republic of Ireland

  Clin Infect Dis, Vol: 39 Page: 173-8 July 2004
  B. Good; C. V. Holland; M. R. Taylor; J. Larragy; P. Moriarty; M. O'Regan

  [Preview] [Read]

Page:
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |