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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Child, Preschool

Your search returns 731 documents

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• 1.   Corneal hysteresis and intraocular pressure measurement in children using the reichert ocular response analyzer

  The aim of this study was to examine corneal hysteresis in children with normal eyes and congenital glaucoma and assess intraocular pressure (IOP) measurement with the Reichert Ocular Response Analyzer (RORA)

  

  Abstract:

  PURPOSE: To examine corneal hysteresis in children with normal eyes and congenital glaucoma and assess intraocular pressure (IOP) measurement with the Reichert Ocular Response Analyzer (RORA). DESIGN: Observational, cross-sectional study. METHODS: setting: Clinical practice. patients: Corneal hysteresis and intraocular pressure (Goldmann correlated [IOPg] and corneal compensated more...

  International Classification:

  Procedure - corneal hysteresis

  Categories:

  corneal hysteresis

  Geography:

  Republic of Ireland

  Am J Ophthalmol, Vol: 142 Page: 990-2 December 2006
  C. Kirwan; M. O'Keefe; B. Lanigan

  [Preview] [Read]

• 2.   Corticosteroids for hospitalised children with acute asthma

  The aim of this review was to determine the benefit of systemic corticosteroids (oral, intravenous, or intramuscular) compared to placebo and inhaled steroids in acute paediatric asthma

  

  Abstract:

  BACKGROUND: Systemic corticosteroids are used routinely in the management of children with severe acute asthma. There is a lack of consensus regarding the agent, dose and route of corticosteroid administration. OBJECTIVES: To determine the benefit of systemic corticosteroids (oral, intravenous, or intramuscular) compared to placebo and inhaled steroids in acute paediatric asthma. SEARCH more...

  International Classification:

  Systematic Review

  Categories:

  systemic corticosteroids paediatric asthma

  Geography:

  Systematic Review

  Cochrane Database Syst Rev, 2003
  M. Smith; S. Iqbal; T. M. Elliott; M. Everard; B. H. Rowe

  [Preview] [Read]

• 3.   Cost effectiveness of hepatitis B vaccination strategies in Ireland: an economic evaluation

  The aim of this study was to undertake an economic evaluation of a universal infant hepatitis B vaccination programme, a six-component vaccine, compared with the current strategy of vaccinating high-risk infants with a monovalent hepatitis B vaccine

  

  Abstract:

  BACKGROUND: In accordance with World Health Organization recommendations, many European countries have introduced universal hepatitis B vaccination policies. The UK and Ireland are exceptions. In this study, we conducted an economic evaluation of a universal infant hepatitis B vaccination programme, using a six-component vaccine, compared with the current selective strategy of more...

  International Classification:

  Economic - Vaccinations

  Categories:

  hepatitis B vaccination

  Geography:

  Republic of Ireland

  Eur J Public Health, Vol: 18 Page: 275-82 June 2008
  L. Tilson; L. Thornton; D. O'Flanagan; H. Johnson; M. Barry

  [Preview] [Read]

• 4.   Cost estimation of injury-related hospital admissions in 10 European countries

  The aim of this study was to undertake a cost estimation of injury-related hospital admissions in 10 European countries

  

  Abstract:

  BACKGROUND: Injuries are a major cause of total health care costs. Cost estimations may help identify injuries and high risk-groups to be considered for potential intervention. METHODS: Hospital discharge registers of 10 European countries were used to estimate injury incidence. Consensus was reached between the participating countries about methodology, definition, classification, cost more...

  International Classification:

  Economic - Injury, poisoning and certain other consequences of external causes-injury

  Categories:

  injury-related hospital admissions

  Geography:

  International

  J Trauma, Vol: 59 Page: 1283-90; discussion 1290-1 December 2005
  S. Polinder; W. J. Meerding; M. E. van Baar; H. Toet; S. Mulder; E. F. van Beeck

  [Preview] [Read]

• 5.   Cryotherapy of viral warts: a sustained 10-s freeze is more effective than the traditional method

  The aim of this study was to assess the efficacy of the traditional freeze and a sustained 10-s freeze in the treatment of common viral warts with liquid nitrogen

  

  Abstract:

  BACKGROUND: Cryotherapy is a standard treatment for viral warts. Although textbooks recommend treating until there is a halo of ice around the wart (traditional freeze), many authors advocate more aggressive cryotherapy. There are no previously published studies assessing the efficacy of longer freezing times. OBJECTIVES: To compare the efficacy of the traditional freeze and a sustained more...

  International Classification:

  Evaluation of the effectiveness of treatments - warts

  Categories:

  common viral warts

  Geography:

  Republic of Ireland

  Br J Dermatol, Vol: 145 Page: 554-7 October 2001
  M. Connolly; K. Bazmi; M. O'Connell; J. F. Lyons; J. F. Bourke

  [Preview] [Read]

• 6.   Cryptorchidism: a general surgical perspective

  This study examined patterns of referral of cryptorchid patients to a surgical clinic, management and follow up

  

  Abstract:

  BACKGROUND: The treatment of cryptorchidism has changed, with surgery now advocated before the age of two years. Delayed treatment affects fertility, malignant potential and psychological stress. AIMS: To assess the pattern of referral of cryptorchid patients to a surgical clinic, management and follow-up. METHODS: A four-year review of 114 cryptorchid patients examined age at more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Congenital malformations of genital organs - cryptorchid

  Geography:

  Republic of Ireland

  Ir J Med Sci, Vol: 172 Page: 139-40 2003 Jul-Sep
  K. T. Lim; R. G. Casey; F. Lennon; P. Gillen; M. Stokes

  [Preview] [Read]

• 7.   Cryptosporidiosis surveillance and water-borne outbreaks in Europe

  This study reports the occurrence - crude incidence rate - of Cryptosporidiosis and water-borne outbreaks in Europe

  

  Abstract:

  Cryptosporidium causes diarrhoeal disease that can be particularly severe in immuno-compromised individuals. Cryptosporidiosis is a notifiable disease at European Union level, and surveillance data are collected through the European Basic Surveillance Network. The disease distribution in Europe for 2005 showed 7,960 cryptosporidiosis cases reported from 16 countries. The crude incidence more...

  International Classification:

  Surveillance - Certain infectious and parasitic diseases - Intestinal infectious diseases - Cryptosporidiosis

  Categories:

  Cryptosporidiosis

  Geography:

  International

  Euro Surveill, Vol: 12 Page: E13-4 May 2007
  J. C. Semenza; G. Nichols

  [Preview] [Read]

• 8.   Custom made alar stents for nostril stenosis: a 24-month evaluation

  This study examined a 24-month evaluation of custom made alar stents for nostril stenosis

  

  Abstract:

  Nostril stenosis is an uncommon deformity and its aetiology is variable. The shape alteration and nostril asymmetry may have negative aesthetic and functional effects on nostril stenosis patients. Five patients were included in this study and followed up for 24 months; four of these had congenital nostril stenosis and one had an acquired deformity. Alar stent dilators were constructed more...

  International Classification:

  Other - nostril stenosis

  Categories:

  nostril stenosis

  Geography:

  Republic of Ireland

  Int J Oral Maxillofac Surg, Vol: 34 Page: 605-11 September 2005
  H. M. Ziada; D. Gavin; P. F. Allen; T. P. O'Connor; K. S. Mehboob Ali

  [Preview] [Read]

• 9.   Cyclooxygenase-2 up-regulation in reflux nephropathy

  The aim of this study was to examine COX-2 expression in the kidneys of children with reflux nephropathy

  

  Abstract:

  PURPOSE: Reflux nephropathy (RN) is a major cause of end stage renal failure in children and hypertension is a frequent complication. Cyclooxygenase-2 (COX-2) is an enzyme responsible for the prostaglandin synthesis. It has been shown that COX-2 up-regulates renin production leading to renovascular hypertension. We investigate COX-2 expression in the kidneys of children with RN. more...

  International Classification:

  Diseases of the genitourinary system - reflux nephropathy

  Categories:

  COX-2 expression; - reflux nephropathy

  Geography:

  Republic of Ireland

  J Urol, Vol: 170 Page: 1624-7 October 2003
  V. Solari; A. P. Piotrowska; S. Cascio; K. Unemoto; B. Chertin; P. Puri

  [Preview] [Read]

• 10.   Cystoid macular oedema in paediatric aphakia and pseudophakia

  This study examined the incidence of cystoid macular oedema, following lensectomy, anterior vitrectomy (limbal and pars plicata), and primary posterior capsulorhexis following surgery for congenital and developmental cataract

  

  Abstract:

  AIM: To assess the incidence of cystoid macular oedema (CMO), following lensectomy, anterior vitrectomy (limbal and pars plicata), and primary posterior capsulorhexis following surgery for congenital and developmental cataract. METHODS: A prospective study was carried out involving 30 eyes (20 children) with cataract. Lensectomy, primary posterior capsulorhexis, and anterior vitrectomy more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities -? - congenital and developmental cataract

  Categories:

  congenital and developmental cataract

  Geography:

  Republic of Ireland

  Br J Ophthalmol, Vol: 90 Page: 37-9 January 2006
  C. Kirwan; M. O'Keeffe

  [Preview] [Read]

• 11.   Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severity

  The aim of this study was to determine whether functional cytokine gene polymorphisms influence disease susceptibility and phenotype in patients with psoriatic arthritis

  

  Abstract:

  OBJECTIVE: To determine whether functional cytokine gene polymorphisms influence disease susceptibility and phenotype in patients with psoriatic arthritis (PsA). METHODS: DNA was obtained from 147 PsA patients and 389 controls. Seven functional proinflammatory (interleukin-1beta [IL-1beta] +3953, IL-6 -174, tumor necrosis factor alpha [TNFalpha] -308, TNFbeta +252) and antiinflammatory more...

  International Classification:

  Diseases of the musculoskeletal system and connective tissue - Papulosquamous disorders - psoriatic arthritis

  Categories:

  functional cytokine gene polymorphisms; -psoriatic arthritis

  Geography:

  Republic of Ireland

  Arthritis Rheum, Vol: 48 Page: 1408-13 May 2003
  J. Balding; D. Kane; W. Livingstone; L. Mynett-Johnson; B. Bresnihan; O. Smith; O. FitzGerald

  [Preview] [Read]

• 12.   Day-care and meningococcal disease in young children

  The aim of this study was to determine if day-care attendance was a risk factor for meningococcal disease

  

  Abstract:

  The Republic of Ireland has the highest incidence of meningococcal disease in Europe with 40% of all cases occurring in children under the age of 5 years. Attending day-care increases the risk of certain infections, including Haemophilus influenzae type b (Hib) meningitis. The risk of meningococcal disease associated with day-care is not known. We conducted a case-control study among more...

  International Classification:

  Certain infectious and parasitic diseases - Other bacterial diseases - meningococcal disease

  Categories:

  day-care attendance; - meningococcal disease

  Geography:

  Republic of Ireland

  Epidemiol Infect, Vol: 127 Page: 435-41 December 2001
  T. Grein; D. O'Flanagan

  [Preview] [Read]

• 13.   Dead cattle, lead and child health

  This aim of this study was to screen for lead toxicity in a local school population

  

  Abstract:

  This study was carried out as part of a larger interagency investigation in response to concerns about human health following the death of three cattle from lead poisoning in an old lead mining area in Silvermines, Tipperary. Its aim was to screen for lead toxicity in the local child population. Screening consisted of measurement of blood lead concentrations and the completion of more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - Toxic effects of substances chiefly nonmedicinal as to source - lead toxicity

  Categories:

  lead toxicity

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 96 Page: 232-4 September 2003
  E. Feely; C. Garavan; K. Kelleher

  [Preview] [Read]

• 14.   Deafness associated with bilateral facial diplegia, ptosis and hypermobile joints--A new autosomal recessive condition?

  This case report discusses the combination of sensorineural deafness with facial diplegia, ptosis and hypermobile joints in a brother and sister

  

  Abstract:

  We report the combination of sensorineural deafness with facial diplegia, ptosis and hypermobile joints. Observed in a sister and brother, comparison with other reports has failed to identify an established syndrome with this clinical profile. We propose that these siblings share a unique phenotype, representing a new autosomal recessive trait. more...

  International Classification:

  Diseases of the ear and mastoid process - Report

  Categories:

  sensorineural deafness

  Geography:

  Republic of Ireland

  Am J Med Genet A, Vol: 122A Page: 84-8 September 2003
  W. Reardon; M. McGinn; M. D. King; M. Earley

  [Preview] [Read]

• 15.   Deaths from blunt trauma, after arrival at hospital: plus ca change, plus c'est la meme chose

  This study examined 94 deaths from blunt trauma occurring after admission to the hospital, in the region of Northern Ireland, for the year of 2001, data is presented with reference to preventable deaths

  

  Abstract:

  In this retrospective review of 94 deaths from blunt trauma occurring after admission to the hospital, in the region of Northern Ireland, for the year of 2001, data is presented with reference to preventable deaths (10%). Comparison is made with previous audit from the year of 1981 (preventable death rate 16%). Adverse events continue to occur in relation to abdominal haemorrhage, and more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury (external blunt trama)

  Categories:

  blunt trauma

  Geography:

  Northern Ireland

  Injury, Vol: 36 Page: 47-50 January 2005
  D. Gilroy

  [Preview] [Read]

• 16.   Deceased-donor kidney transplantation in prune belly syndrome

  The aim of this study was to determine the long-term outcome of deceased-donor kidney transplantation in prune belly syndrome

  

  Abstract:

  OBJECTIVES: To present the long-term outcome of deceased-donor kidney transplantation in prune belly syndrome (PBS). All the PBS transplant patients had undergone extensive pretransplant urologic tract preparation. We also compared the patient and graft survival in an age-matched control group who underwent transplantation for end-stage renal disease due to a nonposterior urethral valve more...

  International Classification:

  Organ transplants - kidney

  Categories:

  donor kidney transplantation; -prune belly syndrome

  Geography:

  Republic of Ireland

  Urology, Vol: 69 Page: 666-9 April 2007
  M. H. Kamel; A. A. Thomas; F. M. Al-Mufarrej; P. O'Kelly; D. P. Hickey

  [Preview] [Read]

• 17.   Decision making in asthma exacerbation: a clinical judgement analysis

  This study aimed to explore a clinical judgement analysis, which provides a methodology for comparing decisions between practitioners with different training and experience, and improving decision making on acute asthma attacks

  

  Abstract:

  BACKGROUND: Clinical decisions which impact directly on patient safety and quality of care are made during acute asthma attacks by individual doctors based on their knowledge and experience. Decisions include administration of systemic corticosteroids (CS) and oral antibiotics, and admission to hospital. Clinical judgement analysis provides a methodology for comparing decisions between more...

  International Classification:

  Practice/knowledge - Diseases of the respiratory system-asthma

  Categories:

  asthma;

  Geography:

  Northern Ireland

  Arch Dis Child, Vol: 92 Page: 672-7 August 2007
  J. Jenkins; M. Shields; C. Patterson; F. Kee

  [Preview] [Read]

• 18.   Decline in mortality, AIDS, and hospital admissions in perinatally HIV-1 infected children in the United Kingdom and Ireland

  The aim of this study was to examine changes in demographic factors, disease progression, hospital admissions and the use of Antiretroviral Therapy in children with HIV

  

  International Classification:

  Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV

  Categories:

  HIV

  Geography:

  Republic of Ireland and the United Kingdom

  BMJ: British Medical Journal, Vol: 327 Page: 1019-1023 2003
  D. M. Gibb; T. Duong; P. A. Tookey; M. Sharland; G. Tudor-Williams; V. Novelli; K. Butler; A. Riordan; L. Farrelly; J. Masters; C. S. Peckham; D. T. Dunn

  [Preview] [Read]

• 19.   Dental caries and enamel fluorosis among the fluoridated and non-fluoridated populations in the Republic of Ireland in 2002

  The aim of this study was to compare the prevalence of caries between child and adolescent residents in fluoridated and non-fluoridated communities in the RoI whilst controlling for disadvantage

  

  Abstract:

  BACKGROUND: A national survey of oral health of children and adolescents was carried out in the Republic of Ireland (RoI) in 2001/2002. AIMS: To compare the prevalence of caries between child and adolescent residents in fluoridated and non-fluoridated communities in the RoI whilst controlling for disadvantage. To compare caries levels amongst disadvantaged and non-disadvantaged groups more...

  International Classification:

  Dental

  Categories:

  dental caries; fluoridated and non-fluoridated communities;

  Geography:

  Republic of Ireland

  Community Dent Health, Vol: 21 Page: 37-44 March 2004
  H. Whelton; E. Crowley; D. O'Mullane; M. Donaldson; V. Kelleher; M. Cronin

  [Preview] [Read]

• 20.   Dental caries, age and anxiety: factors influencing sedation choice for children attending for emergency dental care

  This study aimed to explore how physical (dental caries) and psychosocial (age, dental anxiety and dental health behaviour) factors, associated with child and parent, influenced dentists' sedation choice when a child presents in pain

  

  Abstract:

  OBJECTIVES: The aim of the study was to examine how physical (dental caries) and psychosocial (age, dental anxiety and dental health behaviour) factors, associated with child and parent, influenced dentists' sedation choice when a child presents in pain. METHODS: 600 parents whose children were aged between 5 and 11 years took part: 200 attended for routine dental care (RDC); the more...

  International Classification:

  Practice/knowledge - dental caries

  Categories:

  dental caries

  Geography:

  Northern Ireland

  Community Dent Oral Epidemiol, Vol: 29 Page: 30-6 February 2001
  P. Carson; R. Freeman

  [Preview] [Read]

• 21.   Dental erosion -- changing prevalence? A review of British National childrens' surveys

  The aim of this study was to examine the prevalence of dental erosion, over time, by a review of the data from the published national dental surveys of young people in the United Kingdom

  

  Abstract:

  OBJECTIVES: To investigate the change in the prevalence of dental erosion, over time, by a review of the data from the published national dental surveys of young people in the UK. A subsidiary objective was to investigate the relationship between erosion and possible associated risk factors. DESIGN: The review was based on cross-sectional prevalence studies incorporating a clinical more...

  International Classification:

  Dental

  Categories:

  dental erosion

  Geography:

  the United Kingdom

  Int J Paediatr Dent, Vol: 13 Page: 98-105 March 2003
  J. H. Nunn; P. H. Gordon; A. J. Morris; C. M. Pine; A. Walker

  [Preview] [Read]

• 22.   Dental erosion in 5-year-old Irish school children and associated factors: a pilot study

  The aim of this study was to examine the prevalence of dental erosion in a stratified sample of 5-year-old children and to investigate whether demographic and dietary factors were associated

  

  Abstract:

  OBJECTIVE: To determine the prevalence of dental erosion in a stratified sample of 5-year-old children and to investigate whether demographic and dietary factors were associated. DESIGN: Cross sectional study in Cork City and County. METHODS: A sample of 202 5-year-old children stratified on fluoridation status was selected. Measurement of erosion used a scoring system and criteria more...

  International Classification:

  Dental

  Categories:

  dental erosion

  Geography:

  Republic of Ireland

  Community Dent Health, Vol: 20 Page: 165-70 September 2003
  M. A. Harding; H. Whelton; D. M. O'Mullane; M. Cronin

  [Preview] [Read]

• 23.   Dental experience of cleft affected children in the west of Ireland

  The aim of this study was to examine caries experience and initial access to dental services in a group of children with cleft lip/palate in the west of Ireland

  

  Abstract:

  AIM: To investigate caries experience and initial access to dental services in a group of children with cleft lip/palate in the west of Ireland. DESIGN AND METHOD: Cross sectional study with prospective data capture and matched control. Details of children born with a cleft were obtained from all health professionals likely to be involved in delivering care to these children. Existing more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Cleft lip and/or palate

  Categories:

  caries; dental services; cleft lip/palate

  Geography:

  Republic of Ireland

  Int Dent J, Vol: 51 Page: 73-6 April 2001
  A. R. Hewson; C. M. McNamara; T. F. Foley; J. R. Sandy

  [Preview] [Read]

• 24.   Deprivation, urbanisation and Perthes' disease in Northern Ireland

  The aim of this study was to examine the incidence of Perthes' disease in Northern Ireland

  

  Abstract:

  It has been suggested that Perthes' disease is more prevalent in urban areas, and that the risk increases with deprivation. We present the findings of a preliminary analysis of Perthes' disease in Northern Ireland, which is shown to have one of the highest national annual rates of incidence in the world (11.6 per 100000). Of the 313 children diagnosed over a seven-year period, 311 were more...

  International Classification:

  Diseases of the musculoskeletal system and connective tissue - Osteopathies and chondropathies - Perthes' disease

  Categories:

  Perthes' disease

  Geography:

  Northern Ireland

  J Bone Joint Surg Br, Vol: 82 Page: 167-71 March 2000
  W. D. Kealey; A. J. Moore; S. Cook; A. P. Cosgrove

  [Preview] [Read]

• 25.   Derived manding in children with autism: synthesizing Skinner's verbal behavior with relational frame theory

  The aim of this study was to describe manding in children with autism

  

  Abstract:

  Mand functions for two stimuli (A1 and A2) were trained for 3 children with autism and were then incorporated into two related conditional discriminations (A1-B1/A2 -B2 and B1-C1/B2-C2). Tests were conducted to probe for a derived transfer of mand response functions from A1 and A2 to C1 and C2, respectively. When 1 participant failed to demonstrate derived transfer of mand response more...

  International Classification:

  Mental and behavioural disorders - Disorders of psychological development - autism

  Categories:

  autism; Skinner's verbal behavior with relational frame theory

  Geography:

  Republic of Ireland

  J Appl Behav Anal, Vol: 38 Page: 445-62 2005 Winter
  C. Murphy; D. Barnes-Holmes; Y. Barnes-Holmes

  [Preview] [Read]

• 26.   Dermatological manifestations of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome

  This study examined the dermatological features of Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome in an Irish case series with emphasis on timing of their appearance and association with disease severity

  

  Abstract:

  BACKGROUND: Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome (APECED; OMIM 240300) is a rare autosomal recessive disorder defined by a variable combination of endocrine failure, chronic mucocutaneous candidiasis (CMC), and dystrophy of the dental enamel and nails. APECED is caused by mutations in the autoimmune regulator gene (AIRE). Alopecia areata (AA) and more...

  International Classification:

  Syndrome - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

  Categories:

  autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome

  Geography:

  Republic of Ireland

  Br J Dermatol, Vol: 154 Page: 1088-93 June 2006
  S. M. Collins; M. Dominguez; T. Ilmarinen; C. Costigan; A. D. Irvine

  [Preview] [Read]

• 27.   Desmopressin: therapeutic limitations in children and adults with inherited coagulation disorders

  This study examined haemostatic response to deamino arginine vasopressin in 133 consecutive patients

  

  Abstract:

  Desmopressin (DDAVP), a synthetic analogue of vasopressin has been successfully used in the treatment of type I von Willebrand's disease (VWD), mild factor VIII (FVIII) deficiency and intrinsic platelet function defects (PFDs) for almost three decades. However, there is limited published data documenting its efficacy and the reliability of circulating plasma FVIII:C as a surrogate more...

  International Classification:

  Other - haemostatic response

  Categories:

  deamino arginine vasopressin

  Geography:

  Republic of Ireland

  Br J Haematol, Vol: 109 Page: 865-9 June 2000
  B. Nolan; B. White; J. Smith; C. O'Reily; B. Fitzpatrick; O. P. Smith

  [Preview] [Read]

• 28.   Detection of measles virus in children with ileo-colonic lymphoid nodular hyperplasia, enterocolitis and developmental disorder

  The aim of this study was detect measles virus in children with ileo-colonic lymphoid nodular hyperplasia, enterocolitis and developmental disorder

  

  International Classification:

  Certain infectious and parasitic diseases - Viral infections characterized by skin and mucous membrane lesions - measles

  Categories:

  measles virus; ileo-colonic lymphoid nodular hyperplasia

  Geography:

  Republic of Ireland

  Mol Psychiatry, Vol: 7 Suppl 2 Page: S47-8 2002
  C. M. Martin; V. Uhlmann; A. Killalea; O. Sheils; J. J. O'Leary

  [Preview] [Read]

• 29.   Detection of multiple allergen-specific IgEs on microarrays by immunoassay with rolling circle amplification

  This study aimed to describe the detection of multiple allergen-specific IgEs on microarrays by immunoassay with rolling circle amplification

  

  International Classification:

  Effectiveness of measurement tool - detection of multiple allergen-specific IgEs

  Categories:

  Detection of multiple allergen-specific IgEs

  Geography:

  Northern Ireland

  Clin Chem, Vol: 46 Page: 1990-3 December 2000
  S. Wiltshire; S. O'Malley; J. Lambert; K. Kukanskis; D. Edgar; S. F. Kingsmore; B. Schweitzer

  [Preview] [Read]

• 30.   Detection of non-accidental injuries presenting at emergency departments

  This study aimed to explore whether cases of possible non-accidental injury as identified using five risk indicators give rise to any subjective concerns of child abuse

  

  Abstract:

  OBJECTIVES: To investigate whether cases of possible non-accidental injury as identified using five risk indicators give rise to any subjective concerns of child abuse. METHODS: Questionnaires were completed by the triage nurse and attending doctor for every child attending the general hospitals of the North Western Health Board, with an injury, during a six month period. The more...

  International Classification:

  Practice/knowledge - non-accidental injury

  Categories:

  non-accidental injury, child abuse;

  Geography:

  Republic of Ireland

  Emerg Med J, Vol: 21 Page: 562-4 September 2004
  A. McKinney; G. Lane; F. Hickey

  [Preview] [Read]

• 31.   Detection of sporadic cases of Norwalk-like virus (NLV) and astrovirus infection in a single Irish hospital from 1996 to 1998

  The aim of this study was to examine faeces collected from patients with non-bacterial, non-rotaviral gastroenteritis and examine if Norwalk-like viruses and astroviruses could be identified as the causative agents of the illness

  

  Abstract:

  BACKGROUND: 'Norwalk-like viruses' (NLV) and astroviruses are recognised as the most important etiologic agents of viral gastroenteritis, excluding rotaviruses. However, neither of these two groups of viruses is routinely screened for in Irish hospital laboratories. OBJECTIVE: The objective of this study was to examine faeces collected from patients with non-bacterial, non-rotaviral more...

  International Classification:

  International committee on Taxonomy of Viruses - Norwalk-like viruses, Astroviruses

  Categories:

  Norwalk-like viruses; Astroviruses

  Geography:

  Republic of Ireland

  J Clin Virol, Vol: 17 Page: 109-17 August 2000
  B. Foley; J. O'Mahony; S. M. Morgan; C. Hill; J. G. Morgan

  [Preview] [Read]

• 32.   Determination of verocytotoxin and eae gene loci by multiplex PCR in Escherichia coli O157:H7 isolated from human faeces in Northern Ireland: a four-year study of trends, 1997-2000

  The aim of this study was to examine the distribution and frequency of verocytotoxin genes in human faecal clinical isolates of Escherichia coli O157 in Northern Ireland during the period 1997-2000

  

  Abstract:

  This study aims to determine the distribution and frequency of verocytotoxin genes in human faecal clinical isolates of Escherichia coli O157 in Northern Ireland during the period 1997-2000, using a special four-target multiplex polymerase chain reaction (PCR) assay. One hundred and thirty two isolates of E. coli O157:H7 cultured during the four-year period (1997 [n=28]; 1998 [n=25]); more...

  International Classification:

  Bacterium - Escherichia coli O157

  Categories:

  verocytotoxin genes

  Geography:

  Northern Ireland

  Br J Biomed Sci, Vol: 61 Page: 1-7 2004
  J. L. Crothers; J. E. Moore; B. C. Millar; M. Watabe; P. J. Rooney

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• 33.   Development of a standardized method for comparing fluoride ingested from toothpaste by 1.5-3.5-year-old children in seven European countries. Part 1: Field work

  This study aimed to develop a standardized method for measuring the variables affecting fluoride ingestion from toothpaste in young children between the ages of 1.5 and 3.5 years, and to use the method at seven European sites - Field Work

  

  Abstract:

  OBJECTIVES: To develop a standardized method for measuring the variables affecting fluoride ingestion from toothpaste in young children between the ages of 1.5 and 3.5 years, and to use the method at seven European sites. METHODS: Random samples of children were invited to take part in the study. Parents who gave consent were visited at home. The children brushed their teeth using the more...

  International Classification:

  Effectiveness of measurement tool - fluoride ingestion

  Categories:

  standardized method for measurment; fluoride ingestion; field work;

  Geography:

  International

  Community Dent Oral Epidemiol, Vol: 32 Suppl 1 Page: 39-46 April 2004
  J. A. Cochran; C. E. Ketley; R. M. Duckworth; C. Van Loveren; W. P. Holbrook; L. Seppa; L. Sanches; A. Polychronopoulou; D. M. O'Mullane

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• 34.   Development of a standardized method for comparing fluoride ingested from toothpaste by 1.5-3.5-year-old children in seven European countries. Part 2: Ingestion results

  This study aimed to develop a standardized method for measuring the variables affecting fluoride ingestion from toothpaste in young children between the ages of 1.5 and 3.5 years, and to use the method at seven European sites - Ingestion Results

  

  Abstract:

  OBJECTIVES: To develop a standardized method for measuring the variables affecting fluoride ingestion from toothpaste in young children between the ages of 1.5 and 3.5 years, and to use the method at seven European sites. METHODS: Random samples of children were invited to take part in the study. Parents who gave consent were visited at home. The children brushed their teeth using the more...

  International Classification:

  Effectiveness of measurement tool - fluoride ingestion

  Categories:

  standardized method for measurment; fluoride ingestion; results;

  Geography:

  International

  Community Dent Oral Epidemiol, Vol: 32 Suppl 1 Page: 47-53 April 2004
  J. A. Cochran; C. E. Ketley; R. M. Duckworth; C. van Loveren; W. P. Holbrook; L. Seppa; L. Sanches; A. Polychronopoulou; D. M. O'Mullane

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• 35.   Diabetes care provision and glycaemic control in Northern Ireland: a UK regional audit

  The aim of this study was to audit the care received, compared to national guidelines, and to investigate factors associated with glycaemic control in children and adolescents with type 1 diabetes attending clinics in Northern Ireland

  

  Abstract:

  AIMS: To assess the care received, compared to national guidelines, and to investigate factors associated with glycaemic control in children and adolescents with type 1 diabetes attending clinics in Northern Ireland. METHODS: An audit of the care provided to all patients attending 11 paediatric diabetes clinics commenced in 2002. A research nurse interviewed 914 patients completing a more...

  International Classification:

  Endocrine, nutritional and metabolic diseases - glycaemic control

  Categories:

  glycaemic control

  Geography:

  Northern Ireland

  Arch Dis Child, Vol: 90 Page: 468-73 May 2005
  C. R. Cardwell; C. C. Patterson; M. Allen; D. J. Carson

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• 36.   Diagnosis and management of type 1 laryngeal cleft

  This study demonstrated that type 1 posterior laryngeal clefts are more common than previously described, by reporting a series of 12 type 1 posterior laryngeal clefts diagnosed at our institution over a 12-month period

  

  Abstract:

  Posterior laryngeal clefts have been reported as exceptionally rare congenital anomalies. We demonstrate that type 1 posterior laryngeal clefts are more common than previously described, by reporting a series of 12 type 1 posterior laryngeal clefts diagnosed at our institution over a 12-month period. Typically, type 1 posterior laryngeal clefts are managed conservatively. In our series, more...

  International Classification:

  Other - laryngeal clefts

  Categories:

  posterior laryngeal clefts

  Geography:

  Republic of Ireland

  Int J Pediatr Otorhinolaryngol, Vol: 67 Page: 591-6 June 2003
  K. Watters; J. Russell

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• 37.   Diagnosis of cystic fibrosis in the Republic of Ireland: epidemiology and costs

  The aim of this study was to examine the epidemiology of cystic fibrosis in the Republic of Ireland and the cost implications

  

  Abstract:

  There were four objectives in this study: (1) determine the incidence of cystic fibrosis (CF) in Ireland; (2) estimate the cost of diagnosing CF; (3) clarify the characteristics and outcomes of the nationwide diagnostic efforts and (4) identify disparities. Surveys were conducted to determine the number, methods, costs and outcomes for sweat tests in Ireland from 2001 through 2003. The more...

  International Classification:

  Endocrine, nutritional and metabolic diseases - Metabolic disorders - cystic fibrosis

  Categories:

  cystic fibrosis

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 100 Page: 557-60 September 2007
  P. Farrell; S. Joffe; L. Foley; G. J. Canny; P. Mayne; M. Rosenberg

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• 38.   Diagnostic review of 66 children with learning disability attending a single centre

  The aim of this study was to examine diagnostic criteria of children with learning disabilities attending a single centre

  

  International Classification:

  Disabilities - diagnostic criteria

  Categories:

  diagnostic criteria; disabilities

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 94 Page: 184-5 June 2001
  E. Daly; E. J. MacDermott; A. Green

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• 39.   Differences between males and females in the seasonality of birth and month of clinical onset of disease in children with type 1 diabetes mellitus in Ireland

  The aim of this study was to describe the differences between males and females in the seasonality of birth and month of clinical onset of disease in children with type 1 diabetes mellitus in Ireland

  

  Abstract:

  The aim was to study the monthly rhythm of birth and clinical onset in 303 children with type 1 diabetes mellitus (DM1) aged 0-15 years (156 males, 147 females) born between 1980 and 1996 in Ireland and compare to 951,717 infants born in the general population during the same period. Analysis was performed using the cosine fit for rhythm and t-test between the seasons of the year. more...

  International Classification:

  Endocrine, nutritional and metabolic diseases - Diabetes mellitus - type 1 diabetes mellitus

  Categories:

  type 1 diabetes mellitus

  Geography:

  Republic of Ireland

  J Pediatr Endocrinol Metab, Vol: 16 Page: 779-82 June 2003
  E. F. Roche; H. Lewy; H. M. Hoey; Z. Laron

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• 40.   Discussion groups with parents of children with cerebral palsy in Europe designed to assist development of a relevant measure of environment

  The aim of this study was to inform the content of a questionnaire relevant to the environment of children with cerebral palsy living in Europe

  

  Abstract:

  BACKGROUND: An instrument to measure environmental factors relevant to physically impaired children is being developed in a European context. Preliminary work in England had identified some potentially important themes. Further inquiry was needed to identify issues important in other European countries. OBJECTIVE: To inform the content of a questionnaire relevant to the environment of more...

  International Classification:

  Focus groups - Diseases of the nervous system-cerebral palsy

  Categories:

  questionnaire; cerebral palsy

  Geography:

  International

  Child Care Health Dev, Vol: 32 Page: 185-92 March 2006
  V. McManus; S. I. Michelsen; K. Parkinson; A. Colver; E. Beckung; O. Pez; B. Caravale

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• 41.   Displaced supracondylar fractures of the humerus in children

  This study examined displaced supracondylar fractures of the humerus in children

  

  Abstract:

  We performed an outcome study of completely displaced supracondylar fractures in children in order to assess the outcome of primary open reduction and internal fixation for these injuries. A total of 16 patients (mean age of 5.9 years) were included in the study. The mean follow-up was 2.6 years and patients were assessed after fracture healing using the criteria of Flynn et al. and more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury

  Categories:

  supracondylar fractures

  Geography:

  Republic of Ireland

  Int Orthop, Vol: 24 Page: 221-3 2000
  K. J. Mulhall; T. Abuzakuk; W. Curtin; M. O'Sullivan

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• 42.   Distribution of interstitial cells of Cajal in the internal anal sphincter of patients with internal anal sphincter achalasia and Hirschsprung disease

  The aim of this study was to examine the distribution of interstitial cells of Cajal in the normal internal anal sphincter and that of children diagnosed with internal anal sphincter achalasia and Hirschsprung disease

  

  Abstract:

  CONTEXT: Interstitial cells of Cajal (ICCs) are pacemaker cells in the smooth muscles of the gut. The internal anal sphincter (IAS) is the most caudal part of gastrointestinal tract. It has the important function of maintaining fecal continence. It has been proposed that ICCs in the IAS mediate the inhibitory innervation of the recto-anal reflexes. OBJECTIVE: To investigate the more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease

  Categories:

  internal anal sphincter achalasia; -Hirschsprung disease: internal anal sphincter achalasia

  Geography:

  Republic of Ireland

  Arch Pathol Lab Med, Vol: 127 Page: 1192-5 September 2003
  A. P. Piotrowska; V. Solari; P. Puri

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• 43.   Does bladder capacity assessment by frequency/volume chart correlate well with urodynamic estimation in children with spina bifida?

  The aim of the study was to compare assessment of bladder size by urodynamics and using a frequency/volume chart, in children with spina bifida

  

  Abstract:

  INTRODUCTION: Reduced capacity is a common feature of the neuropathic bladder seen in children with spina bifida. This impacts on urinary continence and, in severe cases, may require augmentation cystoplasty. The traditional means of assessing bladder size has been urodynamics. A frequency/volume chart may also provide this information, but the technique may not be so scientifically more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Congenital malformations of the nervous system - spina bifida

  Categories:

  bladder size

  Geography:

  Northern Ireland

  Eur J Pediatr Surg, Vol: 11 Suppl 1 Page: S24-7 December 2001
  D. F. Marshall; V. E. Boston

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• 44.   Does low birthweight predispose to Perthes' disease? Perthes' disease in twins

  The aim of this study was to examine if low birthweight predispose to Perthes' disease

  

  Abstract:

  Out of 320 patients on the Northern Ireland Perthes' database, five were known to be twins. We observed that the low birthweight twin in each case was the affected child. It is proposed that environmental factors associated with low birthweight are involved in the aetiology of Perthes' disease. more...

  International Classification:

  Diseases of the musculoskeletal system and connective tissue - Osteopathies and chondropathies - Perthes' disease

  Categories:

  Perthes' disease

  Geography:

  Northern Ireland

  J Pediatr Orthop B, Vol: 12 Page: 307-10 September 2003
  K. Lappin; D. Kealey; A. Cosgrove; K. Graham

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• 45.   Does the absence of anal reflexes guarantee a "safe bladder" in children with spina bifida?

  The aim of this study was to examine the reliability of the assumption, - neuropathic bladder behaviour is usually predictable and safe in a child with spina bifida - and whether routine urodynamic studies can be, therefore, safely omitted in this group.

  

  Abstract:

  INTRODUCTION: Increased detrusor pressure is a risk factor for renal damage in patients with neuropathic bladder, and probably requires inappropriate contraction of the external urethral sphincter. It seems logical that the absence of sacrally-mediated anal reflexes in a child with spina bifida makes such sphincteric spasm unlikely. One report has suggested that, in such circumstances, more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Congenital malformations of the nervous system - spina bifida

  Categories:

  neuropathic bladder behaviour; spina bifida

  Geography:

  Northern Ireland

  Eur J Pediatr Surg, Vol: 11 Suppl 1 Page: S21-3 December 2001
  D. F. Marshall; V. E. Boston

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• 46.   Does the addition of sublingual gland excision to submandibular duct relocation give better overall results in drooling control?

  The aim of this study was to compare both sublingual gland excision to submandibular duct relocation including operative time, length of hospital stay, postoperative complications, drooling scores and parental satisfaction

  

  Abstract:

  SUMMARY: Submandibular duct relocation plus or minus excision of the sublingual glands are relatively simple procedures with low morbidity. Between 1981 and 2005, 71 submandibular duct relocation and 29 submandibular duct relocation plus excision of the sublingual glands procedures were conducted. OBJECTIVES: To compare both procedures including operative time, length of hospital stay, more...

  International Classification:

  Procedure - submandibular duct relocation

  Categories:

  submandibular duct relocation

  Geography:

  Republic of Ireland

  Clin Otolaryngol, Vol: 32 Page: 103-7 April 2007
  F. Glynn; T. P. O'Dwyer

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• 47.   Does the risk of acute rejection really decrease with increasing recipient age?

  This study examined the major factors affecting graft survival in cadaveric kidney transplants

  

  Abstract:

  In corneal transplants the risks of acute rejection and graft failure decrease with increasing recipient age, but kidney graft survival analyses tend to show the opposite effect. Why is this? Cadaveric kidney transplants performed in the UK and Republic of Ireland between 1985 and 1993 (UKTSSA database) were analysed by multifactorial methods to identify major factors affecting graft more...

  International Classification:

  Organ transplants - renal

  Categories:

  major factors affecting kidney transplants graft survival

  Geography:

  Republic of Ireland and the United Kingdom

  Transpl Int, Vol: 13 Suppl 1 Page: S42-4 2000
  B. A. Bradley

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• 48.   Dopaminergic system genes in ADHD: toward a biological hypothesis

  The aim of this study was to examine issues about dopaminergic system genes in attention-deficit hyperactivity disorder and generate biological hypothesis

  

  Abstract:

  Converging evidence has implicated abnormalities of dopamine neurotransmission to the pathology of attention deficit hyperactivity disorder (ADHD). Several genetic association studies have been published, but so far, no DNA variants have been unequivocally demonstrated as contributing to ADHD susceptibility. Four dopamine related gene loci have been implicated, however: DAT 1, DRD 4, more...

  International Classification:

  Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder

  Categories:

  attention-deficit hyperactivity disorder

  Geography:

  Republic of Ireland

  Neuropsychopharmacology, Vol: 27 Page: 607-19 October 2002
  A. Kirley; Z. Hawi; G. Daly; M. McCarron; C. Mullins; N. Millar; I. Waldman; M. Fitzgerald; M. Gill

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• 49.   Dublin reminds us about measles

  This article discusses measles in Ireland

  

  Geography:

  Republic of Ireland

  Pediatr Infect Dis J, Vol: 22 Page: 579 July 2003
  S. L. Katz

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• 50.   Early postnatal dexamethasone and cerebral palsy

  This article discusses the early postnatal dexamethasone and cerebral palsy

  

  Geography:

  Northern Ireland

  Pediatrics, Vol: 109 Page: 1168-9 June 2002
  H. L. Halliday

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• 51.   Eat up!

  This article discusses what we feed our infants and toddlers today will significantly influence the health of the Irish population in 40-50 years time

  

  Abstract:

  What we feed our infants and toddlers today will signficantly influence the health of the Irish population in 40-50 years time. more...

  Geography:

  Republic of Ireland

  World of Irish Nursing & Midwifery, Vol: 16 Page: 45-45 2008
  O. Fens

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