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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Child, Preschool

Your search returns 731 documents

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• 1.   Anaesthesia for children with epidermolysis bullosa: a review of 20 years' experience

  This study presented perioperative management of children with epidermolysis bullosa

  

  Abstract:

  BACKGROUND AND OBJECTIVE: Epidermolysis bullosa is a rare, genetically determined disorder characterized by excessive susceptibility of the skin and mucosa to separate from the underlying tissues after mechanical trauma. Patients suffering from this disease may have multiple medical problems, but the risk of anaesthesia is attributed mainly to oropharyngeal involvement; airway more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations - epidermolysis bullosa

  Categories:

  epidermolysis bullosa

  Geography:

  Republic of Ireland

  Eur J Anaesthesiol, Vol: 18 Page: 745-54 November 2001
  G. Iohom; B. Lyons

  [Preview] [Read]

• 2.   Anesthesia for sickle cell disease and congenital myopathy in combination

  This case report discusses the perioperative management of anesthesia and analgesia in a child with sickle cell disease and a congenital myopathy, presenting for corrective orthopedic surgery

  

  Abstract:

  We report on the perioperative management of anesthesia and analgesia in a child with sickle cell disease and a congenital myopathy, presenting for corrective orthopedic surgery. The case illustrates two valuable points of interest: the many benefits of regional anesthesia in complex medical cases and the successful use of tourniquets in children with sickle cell disease. more...

  International Classification:

  Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - Report

  Categories:

  sickle cell disease; corrective orthopedic surgery

  Geography:

  Republic of Ireland

  Paediatr Anaesth, Vol: 16 Page: 880-3 August 2006
  R. Fanning; B. O'Donnell; B. Lynch; M. Stephens; F. O'Donovan

  [Preview] [Read]

• 3.   Anesthetic management of preschool children with penetrating eye injuries: postal survey of pediatric anesthetists and review of the available evidence

  This study aimed to explore pediatric anesthetists regarding their anesthesia management of a screaming child with a penetrating eye injury

  

  Abstract:

  BACKGROUND: Pediatric anesthetists were surveyed regarding their anesthesia management of a screaming child with a penetrating eye injury. The results are reviewed in relation to the available evidence in the literature. METHODS: A postal survey was sent to all the members of the APA living in the UK. Seven clinical questions were asked regarding the management of penetrating eye injury more...

  International Classification:

  Practice/knowledge - management of a screaming child with a penetrating eye injury

  Categories:

  management of a screaming child with a penetrating eye injury

  Geography:

  Republic of Ireland and the United Kingdom

  Paediatr Anaesth, Vol: 16 Page: 769-76 July 2006
  J. Seidel; T. Dorman

  [Preview] [Read]

• 4.   Angiotensin-converting enzyme genotype distribution in familial vesicoureteral reflux

  The aim of this study was to examine the ACE I/D genotype pattern in familial vesicoureteric reflux patients

  

  Abstract:

  Vesicoureteric reflux (VUR) is known to occur in families. In siblings of index patients with VUR, there is a much higher incidence (16% to 46%) than in the general population. The renin-angiotensin system plays an important role in renal development. Recently, it has been reported that angiotensin-converting enzyme (ACE) I/D gene polymorphism is a risk factor for renal parenchymal more...

  International Classification:

  Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux

  Categories:

  vesicoureteric reflux

  Geography:

  Republic of Ireland

  Pediatr Surg Int, Vol: 17 Page: 308-11 May 2001
  A. Yoneda; T. Oue; P. Puri

  [Preview] [Read]

• 5.   Ankle fractures: emergency department management...is there room for improvement?

  This study examined pitfalls in the acute management of ankle fractures which were referred to a regional orthopaedic unit

  

  Abstract:

  OBJECTIVE: The aim of this study was to identify pitfalls in the acute management of ankle fractures which were referred to a regional orthopaedic unit. This unit provides orthopaedic services for the catchment area of the Waterford Emergency Department together with three additional emergency units in the south-eastern region of Ireland. METHODS: This is a retrospective study of all more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - fractures

  Categories:

  ankle fractures

  Geography:

  Republic of Ireland

  Eur J Emerg Med, Vol: 12 Page: 216-9 October 2005
  C. Deasy; D. Murphy; G. C. McMahon; I. P. Kelly

  [Preview] [Read]

• 6.   Antibiotic resistance in Burkholderia cepacia at two regional cystic fibrosis centres in Northern Ireland: is there a need for synergy testing?

  The aim of this study was to examine the susceptibility of wild-type Burkholderia cepacia isolates from all infected adults and children with cystic fibrosis due to a wide variety of antimicrobial agents

  

  International Classification:

  Endocrine, nutritional and metabolic diseases - Metabolic disorders - cystic fibrosis

  Categories:

  cystic fibrosis

  Geography:

  Northern Ireland

  J Antimicrob Chemother, Vol: 48 Page: 319-21 August 2001
  J. E. Moore; M. Crowe; A. Shaw; J. McCaughan; A. O. Redmond; J. S. Elborn

  [Preview] [Read]

• 7.   Antimicrobial prophylaxis in otorhinolaryngology/head and neck surgery

  The aim of this study was to evaluate the use, timing and appropriateness of antimicrobial prophylaxis perioperatively, in otorhinolaryngological/head and neck procedures.

  

  Abstract:

  Prophylactic antimicrobial therapy is defined as the administration of an antimicrobial agent prior to contamination of previously sterile tissues or fluids, in an attempt to reduce the microbial burden of intraoperative contamination. Prophylactic antimicrobial therapy should cover the anticipated floral contamination, with therapeutic levels from incision to closure. There is level I more...

  International Classification:

  Procedure - otorhinolaryngological

  Categories:

  otorhinolaryngological

  Geography:

  Republic of Ireland

  Clin Otolaryngol, Vol: 32 Page: 204-7 June 2007
  B. G. Fennessy; M. Harney; M. J. O'Sullivan; C. Timon

  [Preview] [Read]

• 8.   Antimicrobial susceptibility of invasive isolates of Streptococcus pneumoniae in Ireland

  The aim of this study was to measure antimicrobial susceptibility of invasive isolates of Streptococcus pneumoniae in Ireland

  

  Abstract:

  Between January 1999 and June 2002, 646 invasive isolates of Streptococcus pneumoniae were collected in Ireland. MICs of penicillin, ciprofloxacin, cefotaxime, moxifloxacin and linezolid were determined by Etest methodology. Eighty-seven (13.5%) isolates showed intermediate resistance to penicillin, while seven (1.1%) showed high-level resistance. Eighty-seven (13.5%) isolates were more...

  International Classification:

  Bacterium - Streptococcus pneumoniae

  Categories:

  antimicrobial susceptibility; Streptococcus pneumoniae

  Geography:

  International

  Clin Microbiol Infect, Vol: 10 Page: 657-9 July 2004
  P. Clarke; S. Murchan; E. G. Smyth; H. Humphreys

  [Preview] [Read]

• 9.   Antimicrobial susceptibility of lower respiratory tract pathogens in Great Britain and Ireland 1999-2001 related to demographic and geographical factors: the BSAC Respiratory Resistance Surveillance Programme

  The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors

  

  Abstract:

  OBJECTIVE: The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors using multiple logistic regression analysis. METHODS: A total of 1328 isolates of Streptococcus pneumoniae, 1894 Haemophilus influenzae and 845 Moraxella more...

  International Classification:

  Diseases of the respiratory system - lower respiratory pathogens

  Categories:

  lower respiratory pathogens

  Geography:

  Republic of Ireland and the United Kingdom

  J Antimicrob Chemother, Vol: 52 Page: 931-43 December 2003
  R. Reynolds; J. Shackcloth; D. Felmingham; A. MacGowan

  [Preview] [Read]

• 10.   Antioxidants and oxidative stress in BAL fluid of atopic asthmatic children

  The aim of this study was to compare the concentrations of antioxidants and protein carbonyls in bronchoalveolar lavage fluid of clinically stable atopic asthmatic children with our recently published reference intervals for nonasthmatic children

  

  Abstract:

  Earlier studies in adults have indicated that increased oxidative stress may occur in the blood and airways of asthmatic subjects. Therefore the aim of this study was to compare the concentrations of antioxidants and protein carbonyls in bronchoalveolar lavage fluid of clinically stable atopic asthmatic children (AA, n = 78) with our recently published reference intervals for more...

  International Classification:

  Diseases of the respiratory system - Chronic lower respiratory diseases - asthma

  Categories:

  asthma

  Geography:

  Northern Ireland

  Pediatr Res, Vol: 53 Page: 375-81 March 2003
  B. C. Schock; I. S. Young; V. Brown; P. S. Fitch; M. D. Shields; M. Ennis

  [Preview] [Read]

• 11.   Antiseptic wick: does it reduce the incidence of wound infection following appendectomy?

  The aim of this study was to assess the potential use of wound wicks to reduce the rate of infection following appendectomy

  

  Abstract:

  The role of prophylactic antibiotics is well established for contaminated wounds, but the use of antiseptic wound wicks is controversial. The aim of this work was to study the potential use of wound wicks to reduce the rate of infection following appendectomy. This prospective randomized controlled clinical trial was conducted at a university hospital in the department of surgery. The more...

  International Classification:

  Evaluation of the effectiveness of treatments - following appendectomy

  Categories:

  rate of infection following appendectomy

  Geography:

  Republic of Ireland

  World J Surg, Vol: 26 Page: 631-4 May 2002
  G. T. McGreal; A. Joy; B. Manning; J. L. Kelly; J. A. O'Donnell; W. W. Kirwan; H. P. Redmond

  [Preview] [Read]

• 12.   Apparent low immunisation uptake in Dublin: under-performance or under-recording?

  The aim of this study was to measure apparent low immunisation uptake in Dublin and examine if this is a result of under-performance or under-recording

  

  Abstract:

  Through careful follow-up of a cohort, born March to August 1994, we have recorded the highest ever primary immunisation uptake figures for the Dublin area, with completed uptake for Diphtheria, Tetanus and Oral Polio of 92.1%, Haemophilus influenzae type b of 88.7%, Pertussis of 85.7% and Measles/Mumps/Rubella of 78.1%. Eastern Health Board uptake estimates for the same period are more...

  International Classification:

  Vaccination

  Categories:

  immunisation uptake

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 93 Page: 239-40 November 2000
  P. M. Harrington; C. Woodman; W. F. Shannon

  [Preview] [Read]

• 13.   Application of restriction fragment length polymorphism analysis of VP7-encoding genes: fine comparison of Irish and global rotavirus isolates

  The aim of the study was to compare restriction fragment length polymorphism detection assay developed to examine the genetic relationship(s) among VP7-encoding genes from 100 Irish rotavirus isolates and 30 randomly selected global rotavirus isolates

  

  Abstract:

  A restriction fragment length polymorphism (RFLP) detection assay was developed to examine the genetic relationship(s) among VP7-encoding genes from 100 Irish rotavirus isolates and 30 randomly selected global rotavirus isolates (from the current databases). RFLP analysis of the VP7 gene segments was performed independently with three enzymes (RsaI, AluI, and EcoRV) in separate more...

  International Classification:

  International committee on Taxonomy of Viruses - rotavirus

  Categories:

  rotavirus

  Geography:

  Republic of Ireland

  J Clin Microbiol, Vol: 40 Page: 524-31 February 2002
  F. O'Halloran; M. Lynch; B. Cryan; S. Fanning

  [Preview] [Read]

• 14.   Are hospital based notifications enough? Achieving accurate case ascertainment--the Southern Ireland Cerebral Palsy Register (SICPR)

  The aim of this study was to examine the accuracy of case ascertainment for the Southern Ireland Cerebal Palsy register

  

  Abstract:

  The Southern Ireland Cerebral Palsy Register (SICPR) attempts to identify all cases of cerebral palsy in the Southern Health Board region. Multiple sources of case ascertainment are necessary to achieve a complete register. The aims of the study were to ensure the accuracy of case ascertainment to this register. A postal survey to all general practitioners in the Southern Health Board more...

  International Classification:

  Diseases of the nervous system - Cerebral palsy and other paralytic syndromes - cerebral palsy

  Categories:

  Southern Ireland Cerebal Pasly register

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 98 Page: 24 January 2005
  V. McManus; D. Coghlan

  [Preview] [Read]

• 15.   Arterial reconstruction using the basilic vein from the zone of injury in pediatric supracondylar humeral fractures: a clinical and radiological series

  This study describes the advantages of using the basilic vein as an arterial conduit in the management of children with supracondylar humeral fractures requiring vascular repair.

  

  Abstract:

  The authors describe the advantages of using the basilic vein as an arterial conduit in the management of children with supracondylar humeral fractures requiring vascular repair. Eight children, aged 3 to 10 years, presented with supracondylar humeral fractures and vascular injury. In all eight children, the arteries were successfully reconstructed with a reversed, interposition basilic more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - fractures

  Categories:

  supracondylar humeral fractures

  Geography:

  Northern Ireland

  Plast Reconstr Surg, Vol: 111 Page: 1159-63; discussion 1164-6 March 2003
  H. G. Lewis; C. M. Morrison; P. T. Kennedy; K. J. Herbert

  [Preview] [Read]

• 16.   Assessing ASDs prior to device closure using 3D echocardiography. Just pretty pictures or a useful clinical tool?

  This study aimed to determine the usefulness of three-dimensional transthoracic echocardiography (3D echo) in assessment of secundum atrial septal defects (ASDs) considered for device closure

  

  Abstract:

  AIMS: To determine the usefulness of three-dimensional transthoracic echocardiography (3D echo) in assessment of secundum atrial septal defects (ASDs) considered for device closure. To compare the findings from 3D echo with those from two-dimensional transoesophageal echocardiography (TOE) regarding dimensions, morphology and suitability for device closure. METHODS AND RESULTS: more...

  International Classification:

  Effectiveness of measurement tool - three-dimensional transthoracic echocardiography

  Categories:

  three-dimensional transthoracic echocardiography; atrial septal defects

  Geography:

  Northern Ireland

  Eur J Echocardiogr, Vol: 9 Page: 478-82 July 2008
  G. J. Morgan; F. Casey; B. Craig; A. Sands

  [Preview] [Read]

• 17.   Assessing services, supports and costs for young families under stress

  The aim of this study was to examined the practical feasibility of a methodology for collecting service use data and other information on families

  

  Abstract:

  BACKGROUND: Despite the attention paid to family support services in legislation and guidance, there is still relatively little evidence on which to base the development of effective services, and even less on the costs and cost-effectiveness of different models of support. METHODS: The study designed and examined the practical feasibility of a methodology for collecting service use more...

  International Classification:

  Economic - Health service provision-service use data

  Categories:

  collecting service use data

  Geography:

  the United Kingdom

  Child Care Health Dev, Vol: 32 Page: 101-10 January 2006
  M. Sleed; J. Beecham; M. Knapp; C. McAuley; N. McCurry

  [Preview] [Read]

• 18.   Assessing the burden of injury in six European countries

  This aim of this study was to assess injury-related mortality, disability and disability-adjusted life years (DALYs) in six European countries

  

  Abstract:

  OBJECTIVE: To assess injury-related mortality, disability and disability-adjusted life years (DALYs) in six European countries. METHODS: Epidemiological data (hospital discharge registers, emergency department registers, mortality databases) were obtained for Austria, Denmark, Ireland, Netherlands, Norway, and the United Kingdom (England and Wales). For each country, the burden of more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury

  Categories:

  injury-related mortality; injury-related disability; disability-adjusted life years

  Geography:

  International

  Bull World Health Organ, Vol: 85 Page: 27-34 January 2007
  S. Polinder; W. J. Meerding; S. Mulder; E. Petridou; E. van Beeck

  [Preview] [Read]

• 19.   Assessment of the influence of background noise on escape-maintained problem behavior and pain behavior in a child with Williams syndrome

  This case report examine the influence of background noise on levels of problem behaviour and pain behaviour under functional analysis conditions for a child with a diagnosis of Williams syndrome and hyperacusis

  

  Abstract:

  We examined the influence of background noise on levels of problem behavior and pain behavior under functional analysis conditions for a child with a diagnosis of Williams syndrome and hyperacusis. Background noise was associated with increases in escape-maintained problem behavior and increases in pain behavior such as clasping ears and crying. When the child was fitted with earplugs, more...

  International Classification:

  Mental and behavioural disorders - Report

  Categories:

  problem behaviour

  Geography:

  Republic of Ireland

  J Appl Behav Anal, Vol: 33 Page: 511-4 2000 Winter
  M. F. O'Reilly; C. Lacey; G. E. Lancioni

  [Preview] [Read]

• 20.   Association of the interleukin 1 receptor antagonist gene with ulcerative colitis in Northern European Caucasians

  The aim of this study was to examine the association between the allele 2 of the interleukin 1 receptor antagonist gene

  

  Abstract:

  BACKGROUND AND AIMS: An association between the allele 2 of the interleukin 1 receptor antagonist gene variable number tandem repeats polymorphism in intron 2 and ulcerative colitis was first reported in 1994. Subsequent studies in Caucasian Northern European patients have not confirmed this, although trends towards an association were observed. The lack of statistical significance more...

  International Classification:

  Diseases of the digestive system - Noninfective enteritis and colitis - ulcerative colitis

  Categories:

  allele 2 of the interleukin 1 receptor antagonist gene variable; -ulcerative colitis

  Geography:

  International

  Gut, Vol: 48 Page: 461-7 April 2001
  M. J. Carter; F. S. di Giovine; S. Jones; J. Mee; N. J. Camp; A. J. Lobo; G. W. Duff

  [Preview] [Read]

• 21.   Association of transforming growth factor-beta1 gene polymorphism with reflux nephropathy

  The aim of this study was to investigate genotype frequencies for polymorphisms of the TGF-beta1 gene at position -509, codon 10 and 25, and examine circulating levels of TGF-beta1 in patients with reflux nephropathy

  

  Abstract:

  PURPOSE: Reflux nephropathy (RN) is recognized as a major cause of end stage renal failure in children and young adults. Transforming growth factor-beta1 (TGF-beta1) is a potent proinflammatory and fibrogenetic cytokine known to have a key role in the regulation of renal tissue fibrosis. We investigate genotype frequencies for polymorphisms of the TGF-beta1 gene at position -509, codon more...

  International Classification:

  Diseases of the genitourinary system - reflux nephropathy

  Categories:

  genotype frequencies for polymorphisms of the TGF-beta1 gene; - reflux nephropathy

  Geography:

  Republic of Ireland

  J Urol, Vol: 174 Page: 1609-11; discussion 1611 October 2005
  V. Solari; D. Owen; P. Puri

  [Preview] [Read]

• 22.   Asthma management: in case of an exacerbation

  This article discusses the advantages of having a written asthma action plan to aid in recovery for an exacerbation of asthma

  

  Abstract:

  A written asthma action plan is the key to successful recovery from an exacerbation of asthma, whether managed at home or in hospital, writes Ursula Caulfield. more...

  Geography:

  Republic of Ireland

  World of Irish Nursing & Midwifery, Vol: 13 Page: 37-39 2005
  U. Caulfield

  [Preview] [Read]

• 23.   Asymptomatic ascariasis infection in a child

  This case report discusses a case of asymptomatic ascariasis in a child

  

  International Classification:

  Certain infectious and parasitic diseases - Report

  Categories:

  asymptomatic ascariasis

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 94 Page: 276 October 2001
  J. Costello; P. Keenan

  [Preview] [Read]

• 24.   Atrioventricular block after transcatheter closure of perimembranous ventricular septal defects

  This case report discusses atrioventricular block after transcatheter closure of perimembranous ventricular septal defects

  

  Abstract:

  OBJECTIVE: To look at the presentation, treatment and outcome of patients who developed atrioventricular block after transcatheter closure of a perimembranous ventricular septal defect (PMVSD) with the Amplatzer PMVSD device. SETTING: Three tertiary referral centres for paediatric cardiology in two countries. RESULTS: All three patients presented within 10 days of the procedure. All more...

  International Classification:

  Diseases of the circulatory system - Report

  Categories:

  atrioventricular block

  Geography:

  Republic of Ireland

  Heart, Vol: 92 Page: 1295-7 September 2006
  M. A. Walsh; J. Bialkowski; M. Szkutnik; M. Pawelec-Wojtalik; W. Bobkowski; K. P. Walsh

  [Preview] [Read]

• 25.   Atypical distal radial fractures in children

  This study reported on paediatric injuries secondary to the use of the non-motorized microscooter, with findings of a high rate of upper limb trauma, and a distinct injury associated with the scooter

  

  Abstract:

  In a prospective study of paediatric injuries secondary to the use of the non-motorized microscooter, we found a high rate of upper limb trauma, and a distinct injury associated with the scooter. The most common single injury was a fracture of the distal third of radius and ulna, characterized by volar angulation of the distal fragment. This injury, akin to the Smiths fracture in more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury

  Categories:

  paediatric injuries

  Geography:

  Republic of Ireland

  J Pediatr Orthop B, Vol: 13 Page: 202-5 May 2004
  P. D. Kiely; P. J. Kiely; M. M. Stephens; F. E. Dowling

  [Preview] [Read]

• 26.   Atypical Mycobacterial infections in children: the case for early diagnosis

  This case report discusses a case of atypical case of Mycobacteria

  

  Abstract:

  BACKGROUND & AIMS: Atypical Mycobacteria (ATB) are a miscellaneous collection of Mycobacteriaceae which also includes M. tuberculosis, M. bovis and M. leprae. In the paediatric population, ATB infections present with non-tender unilateral lymphadenopathy in a systemically well child. Initially the disease may be mistaken for a staphylococcal or streptococcal abscess. Inappropriate more...

  International Classification:

  Certain infectious and parasitic diseases - Report

  Categories:

  mycobacterial

  Geography:

  Northern Ireland

  Ulster Med J, Vol: 75 Page: 192-4 September 2006
  S. Thavagnanam; L. M. McLoughlin; C. Hill; P. T. Jackson

  [Preview] [Read]

• 27.   Audit of Mobile Intensive Care Ambulance Service

  The aim of this audit was to determine if a centralised retrieval system for interhospital transport of critically ill patients in Ireland by Mobile Intensive Care Ambulance Service is safe and efficient.

  

  Abstract:

  The transfer of critically ill patients between hospitals carries significant risk. The Mobile Intensive Care Ambulance Service (MICAS) in Ireland was established in 1996 to provide a ground transfer service between hospitals for critically ill patients. The aim of this audit was to determine if a centralised retrieval system for interhospital transport of critically ill patients in more...

  International Classification:

  Factors influencing health status and contact with health services - persons encountering health services for examination and investigation - centralised retrieval system for interhospital transport

  Categories:

  centralised retrieval system for interhospital transport

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 99 Page: 76-8 March 2006
  D. Rohan; R. Dwyer; J. Costello; D. Phelan

  [Preview] [Read]

• 28.   Auditory perception and speech discrimination after cochlear implantation in patients with connexin 26 (GJB2) gene-related deafness

  The aim of this study was to examine on connexin 26 gene-related deafness mutation analysis along with speech discrimination assessment was undertaken to assess the impact of pediatric cochlear implantees on these disabilities

  

  Abstract:

  HYPOTHESIS: Auditory perception and speech discrimination among pediatric cochlear implantees may vary because of underlying deafness etiology, including connexin 26 (GJB2) gene-related deafness. BACKGROUND: Preliminary data suggest pathologic changes due to GJB2 mutations do not affect the spiral ganglion cells, which are stimulated by the cochlear implant. The survival of the spiral more...

  International Classification:

  Diseases of the ear and mastoid process - Other disorders of ear - deafness

  Categories:

  deafness; cochlear implant

  Geography:

  Northern Ireland

  Otol Neurotol, Vol: 25 Page: 930-4 November 2004
  A. R. Sinnathuray; J. G. Toner; A. Geddis; J. Clarke-Lyttle; C. C. Patterson; A. E. Hughes

  [Preview] [Read]

• 29.   Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in the Irish population

  The aim of this study was to examine the prevalence of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, the AIRE mutations involved and clinical features of this population

  

  Abstract:

  OBJECTIVE: To determine the Irish prevalence of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), the AIRE mutations involved and clinical features of this population. METHODS: All patients were identified through paediatricians and endocrinologists in Ireland. Patients were invited to attend a multidisciplinary clinic. RESULTS: Thirty-one patients (2-56 years), more...

  International Classification:

  Syndrome - autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

  Categories:

  autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

  Geography:

  Republic of Ireland

  J Pediatr Endocrinol Metab, Vol: 19 Page: 1343-52 November 2006
  M. Dominguez; E. Crushell; T. Ilmarinen; E. McGovern; S. Collins; B. Chang; P. Fleming; A. D. Irvine; D. Brosnahan; I. Ulmanen; N. Murphy; C. Costigan

  [Preview] [Read]

• 30.   Automatic detection of gait events using kinematic data

  The aim of this study was to examine an algorithm which automatically determines the transitions between stance and swing phase of gait using kinematic data recorded by a motion capture system, which is routinely used in gait analysis laboratories.

  

  Abstract:

  The timing of heel strike (HS) and toe off (TO), the events that mark the transitions between stance and swing phase of gait, is essential when analysing gait. Force plate recordings are routinely used to identify these events. Additional instrumentation, such as force sensitive resistors, can also been used. These approaches, however, include restrictions on the number of steps that more...

  International Classification:

  Gait

  Categories:

  gait

  Geography:

  Republic of Ireland

  Gait Posture, Vol: 25 Page: 469-74 March 2007
  C. M. O'Connor; S. K. Thorpe; M. J. O'Malley; C. L. Vaughan

  [Preview] [Read]

• 31.   Autosomal dominant early childhood seizures associated with chondrocalcinosis and a mutation in the ANKH Gene

  This case report describes the pattern of early childhood seizures within a family with autosomal dominant chondrocalcinosis (CCAL, which causes adult-onset arthritis)

  

  Abstract:

  We describe the pattern of early childhood seizures within a family with autosomal dominant chondrocalcinosis (CCAL, which causes adult-onset arthritis). All affected family members with CCAL experienced seizures in early childhood, usually, but not always, associated with fever. Similarities exist to the syndrome of generalized epilepsy with febrile seizures plus (GEFS+). A mutation more...

  International Classification:

  Diseases of the musculoskeletal system and connective tissue - Report

  Categories:

  autosomal dominant chondrocalcinosis;

  Geography:

  Northern Ireland

  Epilepsia, Vol: 45 Page: 1258-60 October 2004
  S. McKee; A. Pendleton; J. Dixey; M. Doherty; A. Hughes

  [Preview] [Read]

• 32.   Autosomal dominant peripheral cystic retinal patches and non-cystic retinal tufts associated with peripapillary crescents, retinal breaks and uveitis

  The aim of this study was to characterise an Irish kindred with apparent autosomal dominant peripheral retinal lesions and peripapillary crescents associated with retinal breaks and uveitis to examine the association with altered homocysteine metabolism

  

  Abstract:

  PURPOSE: To characterise an Irish kindred with apparent autosomal dominant peripheral retinal lesions and peripapillary crescents associated with retinal breaks and uveitis and assess whether these findings were associated with altered homocysteine metabolism. METHODS: Family members were followed prospectively and regularly examined. Molecular genetic analysis was performed on family more...

  International Classification:

  Diseases of the eye and adnexa - Disorders of sclera, cornea, iris and ciliary body - uveitis

  Categories:

  peripheral retinal lesions; uveitis

  Geography:

  Republic of Ireland

  Graefes Arch Clin Exp Ophthalmol, Vol: 239 Page: 102-8 February 2001
  M. Cahill; P. Gallagher; A. Whitehead; R. Acheson

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• 33.   Bacterial colonization of the prepuce in boys with vesicoureteral reflux who receive antibiotic prophylaxis

  The aim of the study was to examine the bacterial colonization of the prepuce in boys with vesicoureteral reflux who receive antibiotic prophylaxis

  

  Abstract:

  Culture swabs were taken from the periurethral area of 59 consecutive uncircumcised boys with vesicoureteral reflux (VUR) and 36 boys undergoing circumcision. A pure growth of a uropathogen was isolated in 22 (37%) boys with VUR who were receiving antibiotic prophylaxis and in 10 (28%) boys who underwent circumcision. Antibiotic prophylaxis in patients with VUR was not effective in more...

  International Classification:

  Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux

  Categories:

  bacterial colonization of the prepuce

  Geography:

  Republic of Ireland

  J Pediatr, Vol: 139 Page: 160-2 July 2001
  S. Cascio; E. Colhoun; P. Puri

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• 34.   Bacterial toxicosis/toxic shock syndrome as a contributor to morbidity in children with burn injuries

  This study examined the cause of the deterioration in thermal injuries and any patterns in their presentation

  

  Abstract:

  When a child with a thermal injury suddenly becomes unwell, it is often difficult to obtain an accurate diagnosis in the early stages of the illness. Out of 71 children admitted to our burns unit over a 15-month period, 13 became acutely toxic. Most of the cases had relatively small burns and the exact reason for their sudden deterioration was not apparent in the immediate stages. more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury

  Categories:

  thermal injuries

  Geography:

  Northern Ireland

  Burns, Vol: 29 Page: 733-8 November 2003
  A. P. Brown; K. Khan; S. Sinclair

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• 35.   Behavioral, developmental, and educational problems in children with nonsyndromic trigonocephaly

  The aim of this study was to examine the degree of developmental, educational, and behavioural problems in nonsyndromic trigonocephaly patients and to establish whether patients with mild degrees of trigonocephaly had a lower frequency of such problems

  

  Abstract:

  OBJECT: The neurobehavioral morbidity of nonsyndromic trigonocephaly is incompletely understood. The purpose of this study was twofold: first, to assess the degree of developmental, educational, and behavioral problems in patients with nonsyndromic trigonocephaly and second, to establish whether patients with mild degrees of trigonocephaly had a lower frequency of such problems. more...

  International Classification:

  Other - nonsyndromic trigonocephaly patients, oxidative stress marker, oxygen saturation in flights, pain (2), parental - perceived parental expectation and criticism,

  Categories:

  nonsyndromic trigonocephaly

  Geography:

  Republic of Ireland

  J Neurosurg, Vol: 105 Page: 382-4 November 2006
  M. O. Kelleher; D. J. Murray; A. McGillivary; M. H. Kamel; D. Allcutt; M. J. Earley

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• 36.   Behavioural and cognitive interventions with or without other treatments for defaecation disorders in children

  The aim of this review was to assess the effects of behavioural and/or cognitive interventions for the management of defaecation disorders in children

  

  Abstract:

  BACKGROUND: Faecal soiling is a common and potentially distressing disorder of childhood. OBJECTIVES: To assess the effects of behavioural and/or cognitive interventions for the management of defaecation disorders in children. SEARCH STRATEGY: The following databases were searched: the Cochrane Incontinence Group Trials Register (March 2001), the Cochrane Controlled Trials Register more...

  International Classification:

  Systematic Review

  Categories:

  behavioural and/or cognitive interventions management of defaecation

  Geography:

  Systematic Review

  Cochrane Database Syst Rev, 2001
  M. Brazzelli; P. Griffiths

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• 37.   Behavioural characteristics and autistic features in individuals with Cohen Syndrome

  The aim of this study was to describe behavioural characteristics and autistic features in individuals with Coen Syndrome

  

  Abstract:

  Diagnostic criteria for Cohen Syndrome are based largely on physical characteristics, and systematic information about behaviour and social functioning is limited. Typically, individuals with this condition are described as being very sociable and as showing low rates of pathology. However, recent studies have indicated that behavioural difficulties may occur more frequently than more...

  International Classification:

  Syndrome - Coen

  Categories:

  Coen Syndrome

  Geography:

  International

  Eur Child Adolesc Psychiatry, Vol: 14 Page: 57-64 March 2005
  P. Howlin; J. Karpf; J. Turk

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• 38.   Belfast Cochlear Implant Centre; the surgical results of the first 100 implants

  This study examined the surgical results of the first one hundred cochlear implant operations at the Belfast Cochlear Implant Centre

  

  Abstract:

  We assess the surgical results of the first one hundred cochlear implant operations at the Belfast Cochlear Implant Centre. This paper is in the form of a retrospective case series, taking into account the surgical technique used and any problems encountered. Initially 28 operations were performed using the standard inverted U-shaped incision. After Gibson and Harrison described a more...

  International Classification:

  Procedure - cochlear implant

  Categories:

  cochlear implant operations

  Geography:

  Northern Ireland

  Rev Laryngol Otol Rhinol (Bord), Vol: 121 Page: 9-11 2000
  S. M. Hampton; J. G. Toner

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• 39.   Bilateral optic disk swelling in the 4q34 deletion syndrome

  This case report discusses a case of 4q deletion syndrome, presenting with asymptomatic bilateral disk swelling

  

  Abstract:

  Terminal deletion of chromosome 4q is a genetic abnormality associated predominantly with cardiac abnormalities, abnormal facial features, and developmental delay. A specific clinical clue to this infrequently diagnosed disorder is hypoplasia of the terminal phalanx of the fifth finger with an abnormal nail, occasionally extending onto the volar surface. Ocular manifestations of the more...

  International Classification:

  Diseases of the eye and adnexa - Report

  Categories:

  asymptomatic bilateral disk swelling

  Geography:

  Republic of Ireland

  J Aapos, Vol: 11 Page: 516-8 October 2007
  P. Connell; D. Brosnahan; A. Dunlop; W. Reardon

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• 40.   Bilateral subdural collections--an unusual feature of possible Kawasaki disease

  This case report discusses a case of possible Kawasaki disease which presented with bilateral subdural collections

  

  Abstract:

  A case of possible Kawasaki disease presenting with bilateral subdural collections is reported. A 6-month-old boy was admitted to hospital following a prolonged partial seizure. He showed signs of worsening encephalopathy and was treated for presumed infective meningoencephalitis. Imaging revealed bilateral subdural collections. Pyrexia and irritability continued despite appropriate more...

  International Classification:

  Syndrome

  Categories:

  Kawasaki syndrome

  Geography:

  Republic of Ireland

  Eur J Paediatr Neurol, Vol: 5 Page: 79-81 2001
  N. M. Bailie; O. J. Hensey; S. Ryan; D. Allcut; M. D. King

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• 41.   Blood splash from different diathermy instruments during tonsillectomy

  The aim of this study was to assess the potential risk of blood contamination of the surgeon's conjunctiva during tonsillectomy using disposable bipolar diathermy and reusable monopolar diathermy

  

  Abstract:

  OBJECTIVE: To compare the potential risk of blood contamination of the surgeon's conjunctiva during tonsillectomy using disposable bipolar diathermy and reusable monopolar diathermy. DESIGN: A prospective, single-blind, randomized, controlled trial. METHODS: Elective tonsillectomy was performed using either disposable bipolar diathermy or reusable monopolar diathermy. The operating more...

  International Classification:

  Evaluation of the effectiveness of prevention of blood contamination

  Categories:

  blood contamination of surgeon

  Geography:

  Northern Ireland

  J Laryngol Otol, Vol: 120 Page: 927-31 November 2006
  B. C. Hanna; P. Thompson; C. Smyth; G. Gallagher

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• 42.   Bone marrow transplantation corrects osteopetrosis in the carbonic anhydrase II deficiency syndrome

  These case reports discuss the cases of 2 related Irish families with clinically severe carbonic anhydrase II deficiency syndrome deficiency in whom the gene mutation has been fully elucidated

  

  Abstract:

  Carbonic anhydrase II (CAII), found in renal tubules, brain, and osteoclasts, is critical in acid-base homeostasis and bone remodeling. Deficiency of CAII gives rise to a syndrome of osteopetrosis, renal tubular acidosis (RTA), and cerebral calcification with associated developmental delay. It is inherited in an autosomal recessive fashion and found most frequently in the Mediterranean more...

  International Classification:

  Syndrome

  Categories:

  Carbonic anhydrase II deficiency syndrome

  Geography:

  Republic of Ireland

  Blood, Vol: 97 Page: 1947-50 April 2001
  C. McMahon; A. Will; P. Hu; G. N. Shah; W. S. Sly; O. P. Smith

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• 43.   Booster immunization of children with an acellular pertussis vaccine enhances Th2 cytokine production and serum IgE responses against pertussis toxin but not against common allergens

  The aim of this study was to examine the persistence of the T-cell response and the effect of booster immunization in 4-6-year-old children

  

  Abstract:

  Acellular pertussis vaccines (Pa) protect against severe pertussis in children. However, serum antibody responses decline quickly after immunization. Studies in animal models suggest that cell-mediated immunity also contributes to protection against Bordetella pertussis, and it has already been demonstrated that Pa induce T cells that secrete type-1 and type-2 cytokines in children. In more...

  International Classification:

  Vaccination

  Categories:

  immunization

  Geography:

  Republic of Ireland

  Clin Exp Immunol, Vol: 121 Page: 193-200 August 2000
  E. J. Ryan; L. Nilsson; N. Kjellman; L. Gothefors; K. H. Mills

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• 44.   Boosting dental registration for children

  This article discusses boosting dental registration for children

  

  Geography:

  Northern Ireland

  Br Dent J, Vol: 199 Page: 411 October 2005

  [Preview] [Read]

• 45.   Botulinum toxin treatment of spasticity in diplegic cerebral palsy: a randomized, double-blind, placebo-controlled, dose-ranging study

  The aim of this study was to assess the efficacy and safety of three doses of botulinum toxin A (BTX-A; Dysport) in 125 patients with dynamic equinus spasticity during walking.

  

  Abstract:

  This study evaluated the efficacy and safety of three doses of botulinum toxin A (BTX-A; Dysport) in 125 patients (mean age 5.2 years, SD 2; 54% male)with dynamic equinus spasticity during walking. Participants were randomized to receive Dysport (10, 20, or 30 units/kg) or placebo to the gastrocnemius muscle of both legs. Muscle length was calculated from electrogoniometric measurements more...

  International Classification:

  Evaluation of the effectiveness of treatment - dynamic equinus spasticity

  Categories:

  botulinum toxin A in the treatment of muscle spasms

  Geography:

  Northern Ireland

  Dev Med Child Neurol, Vol: 44 Page: 666-75 October 2002
  R. Baker; M. Jasinski; I. Maciag-Tymecka; J. Michalowska-Mrozek; M. Bonikowski; L. Carr; J. MacLean; J. P. Lin; B. Lynch; T. Theologis; J. Wendorff; P. Eunson; A. Cosgrove

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• 46.   Bronchoalveolar lavage and tracheal aspirate for assessing airway inflammation in children

  This article discusses the bronchoalveolar lavage and tracheal aspirate for assessing airway inflammation in children

  

  Geography:

  Northern Ireland

  Am J Respir Crit Care Med, Vol: 162 Page: S15-7 August 2000
  M. D. Shields; J. Riedler

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• 47.   Buccinator sandwich pushback: a new technique for treatment of secondary velopharyngeal incompetence

  This study examined the results of a series of patients who had correction of secondary velopharyngeal incompetence using bilateral buccinator musculomucosal flaps

  

  Abstract:

  OBJECTIVE: A small percentage of patients have inadequate velopharyngeal closure, or secondary velopharyngeal incompetence, following primary palatoplasty. Use of the buccinator musculomucosal flap has been described for primary palate repair with lengthening, but its use in secondary palate lengthening for the correction of insufficient velopharyngeal closure has not been described. more...

  International Classification:

  Procedure - velopharyngeal

  Categories:

  velopharyngeal

  Geography:

  Northern Ireland

  Cleft Palate Craniofac J, Vol: 41 Page: 230-7 May 2004
  C. Hill; C. Hayden; M. Riaz; A. G. Leonard

  [Preview] [Read]

• 48.   Cadaveric kidney transplantation in children < or =20 kg in weight: long-term single-center experience

  This study aimed to reported the long-term follow up from cadaveric kidney transplantation in children < or =20 kg in weight

  

  Abstract:

  BACKGROUND: We report long-term follow-up data on cadaveric kidney transplantation in children < or =20 kg in weight. METHODS: Between January 1990 and October 2003, we performed 19 cadaveric renal transplants in 19 children < or =20 kg in weight. Mean age at transplantation was 4.7 years (range 18 months to 9 years). Mean weight at transplantation was 14.4 kg (range 9 to 20 kg). Nine more...

  International Classification:

  Organ transplants - cadaveric

  Categories:

  cadaveric kidney transplantation

  Geography:

  Republic of Ireland

  Transplant Proc, Vol: 37 Page: 685-6 March 2005
  M. H. Kamel; A. Rampersad; P. Mohan; D. P. Hickey; D. M. Little

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• 49.   Calcification of homograft valves in the pulmonary circulation -- is it device or donation related?

  This study examined the effect of type (pulmonary and aortic) and mode of harvest of these cryopreserved homografts (cadaveric and beating heart) on the incidence of calcification of these conduits when used in pulmonary circulation

  

  Abstract:

  OBJECTIVE: Homograft valved conduits are used in the reconstruction of right ventricular outflow tract (RVOT), and calcification is a recognised phenomenon in these devices. The purpose of this study was to assess the effect of type (pulmonary and aortic) and mode of harvest of these cryopreserved homografts (cadaveric and beating heart) on the incidence of calcification of these more...

  International Classification:

  Organ transplants - cryopreserved homografts

  Categories:

  harvest of cryopreserved homografts

  Geography:

  Republic of Ireland

  Eur J Cardiothorac Surg, Vol: 22 Page: 78-81 July 2002
  H. Javadpour; D. Veerasingam; A. E. Wood

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• 50.   Calcium and vitamin D

  This article discusses the role of Calcium and Vitamin D in normal growth and development as well as maintenance of the skeleton

  

  Abstract:

  Calcium is required for normal growth and development as well as maintenance of the skeleton. Vitamin D is also essential for intestinal calcium absorption and plays a central role in maintaining calcium homeostasis and skeletal integrity. In addition, both micronutrients have important roles in non-skeletal-related physiological processes. Of concern, significant proportions of some more...

  Geography:

  Republic of Ireland

  Novartis Found Symp, Vol: 282 Page: 123-38; discussion 138-42, 212-8 2007
  K. D. Cashman

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• 51.   Calculations of dietary exposure to acrylamide

  The aim of this study was to examine usual and acute exposure to acrylamidein the Dutch population and young children

  

  Abstract:

  In this paper we calculated the usual and acute exposure to acrylamide (AA) in the Dutch population and young children (1-6 years). For this AA levels of different food groups were used as collected by the Institute for Reference Materials and Measurements (IRMM) of the European Commission's Directorate General Joint Research Centre (JRC) from April 2003 up to May 2004. This database more...

  International Classification:

  Other - acrylamide

  Categories:

  acrylamide

  Geography:

  International

  Mutat Res, Vol: 580 Page: 143-55 February 2005
  P. E. Boon; A. de Mul; H. van der Voet; G. van Donkersgoed; M. Brette; J. D. van Klaveren

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