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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Child, Preschool

Your search returns 731 documents

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• 1.   Under-reporting of notifiable infectious disease hospitalizations in a health board region in Ireland: room for improvement?

  The aim of this study was to examine the level of hospitalization for notifiable infectious diseases for a 6-year period in one health board region in Ireland and to assess whether or not there was any under-reporting during this period.

  

  Abstract:

  Rapid notification of infectious diseases is essential for prompt public health action and for monitoring of these diseases in the Irish population at both a local and national level. Anecdotal evidence suggests, however, that the occurrence of notifiable infectious diseases is seriously underestimated. This study aims to assess the level of hospitalization for notifiable infectious more...

  International Classification:

  Health service provision

  Categories:

  notifiable infectious diseases

  Geography:

  Republic of Ireland

  Epidemiol Infect, Vol: 136 Page: 241-7 February 2008
  E. D. Brabazon; A. O'Farrell; C. A. Murray; M. W. Carton; P. Finnegan

  [Preview] [Read]

• 2.   Unlinked vital events in census-based longitudinal studies can bias subsequent analysis

  The aim of this study was to examine the potential biases arising from the nonlinkage of census records and vital events in longitudinal studies

  

  Abstract:

  OBJECTIVE: To examine the potential biases arising from the nonlinkage of census records and vital events in longitudinal studies. STUDY DESIGN AND SETTING: A total of 56,396 deaths of residents of Northern Ireland in the 4 years after the 2001 Census were linked to the 2001 Census records. The characteristics of matched and nonmatched death records were compared using multivariate more...

  International Classification:

  Health service provision

  Categories:

  nonlinkage of census records and vital events

  Geography:

  Northern Ireland

  J Clin Epidemiol, Vol: 61 Page: 380-5 April 2008
  D. O'Reilly; M. Rosato; S. Connolly

  [Preview] [Read]

• 3.   Unplanned hospital admission in children undergoing day-case surgery

  The aim of this study was to examine the incidence and causes of unplanned hospital admissions in children undergoing day-case surgery

  

  Abstract:

  BACKGROUND AND OBJECTIVE: Unplanned hospital admission is a measure of quality of care in the setting of day-case surgery. We set out to identify the incidence and causes of unplanned hospital admission in a paediatric day-case unit. METHODS: A retrospective survey to determine the incidence and causes of unplanned hospital admissions in children undergoing day-case surgery. The survey more...

  International Classification:

  Health service provision

  Categories:

  unplanned hospital admissions

  Geography:

  Republic of Ireland

  Eur J Anaesthesiol, Vol: 21 Page: 379-83 May 2004
  I. T. Awad; M. Moore; C. Rushe; A. Elburki; K. O'Brien; D. Warde

  [Preview] [Read]

• 4.   Upregulation of angiotensin II receptors in reflux nephropathy

  The aim of this study was to examine the expression of angiotensin type 1 receptor (AT(1)R) and AT(2)R in severe reflux nephropathy

  

  Abstract:

  BACKGROUND/PURPOSE: Reflux nephropathy (RN) is the cause of end-stage renal failure in 3% to 25% of children and in 10% to 15% of adults. Angiotensin II (Ang II) is a biologically active peptide of the renin-angiotensin system (RAS), which has a profound role not only in the urinary tract-development, but also in the response of the urinary tract to injury. The actions of Ang II are more...

  International Classification:

  Diseases of the genitourinary system - reflux nephropathy

  Categories:

  expression of AT(1)R and AT(2)R; - severe reflux nephropathy

  Geography:

  Republic of Ireland

  J Pediatr Surg, Vol: 37 Page: 251-5 February 2002
  B. Chertin; U. Rolle; S. Cascio; M. McDermot; S. O'Briain; A. Farkas; P. Puri

  [Preview] [Read]

• 5.   Up-regulation of angiotensin-converting enzyme (ACE) gene expression induces tubulointerstitial injury in reflux nephropathy

  The aim of this study was to investigate the expression of angiotensin-converting enzyme in severely refluxing kidneys from eight patients with severe reflux nephropathy secondary to primary high-grade vesicoureteral reflux at nephrectomy

  

  Abstract:

  Reflux nephropathy (RN) is the cause of end-stage renal failure in 3%-25% of children and 10%-15% of adults. Angiotensin-converting enzyme (ACE) converts the inactive decapeptide angiotensin I (Ang I) to the active octapeptide angiotensin II (Ang II), a potent vasoconstrictor. ACE is localized in highest concentrations on the luminal surface of endothelial cells, but is also found in more...

  International Classification:

  Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux

  Categories:

  angiotensin-converting enzyme; - vesicoureteral reflux

  Geography:

  Republic of Ireland

  Pediatr Surg Int, Vol: 18 Page: 635-9 October 2002
  B. Chertin; V. Solari; D. J. Reen; A. Farkas; P. Puri

  [Preview] [Read]

• 6.   Urban-rural variation in mortality and hospital admission rates for unintentional injury in Ireland

  The aim of the study was to compare urban-rural differences in the mortality and hospital admission rates for unintentional injuries in the Republic of Ireland

  

  Abstract:

  OBJECTIVE: To explore urban-rural differences in the mortality and hospital admission rates for unintentional injuries in the Republic of Ireland. DESIGN: Standardised mortality ratios (SMRs) in residents of urban and non-city areas (called rural areas) from all causes of unintentional injury were calculated using Central Statistics Office mortality data from 1980-2000. Hospital more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury

  Categories:

  unintentional injuries

  Geography:

  Republic of Ireland

  Inj Prev, Vol: 11 Page: 38-42 February 2005
  M. Boland; A. Staines; P. Fitzpatrick; E. Scallan

  [Preview] [Read]

• 7.   Urinary fluoride excretion by preschool children in six European countries

  The aim of the study was to compare 24-h urinary fluoride excretion in children aged 1.5-3.5 years from European study sites and to use these data to estimate the 24-h fluoride intake

  

  Abstract:

  OBJECTIVE: To measure and compare 24-h urinary fluoride excretion in children aged 1.5-3.5 years from European study sites and to use these data to estimate the 24-h fluoride intake. METHOD: Twenty-four-hour urine samples were collected from 3-year-old children (n = 86) who were already participating in a European multicentre study. Samples were collected from Cork, Ireland (n = 19) more...

  International Classification:

  Dental

  Categories:

  fluoride excretion

  Geography:

  International

  Community Dent Oral Epidemiol, Vol: 32 Suppl 1 Page: 62-8 April 2004
  C. E. Ketley; J. A. Cochran; W. P. Holbrook; L. Sanches; C. van Loveren; A. M. Oila; D. M. O'Mullane

  [Preview] [Read]

• 8.   Urinary fluoride excretion of young children exposed to different fluoride regimes

  The aim of this study was to examine 24-hour urinary fluoride excretion in young children exposed to different fluoride regimes

  

  Abstract:

  AIMS: To compare 24-hour urinary fluoride excretion in young children exposed to different fluoride regimes. DESIGN: Twenty-four-hour urine samples were collected from children aged between 1.8 and 5.2 years. Samples were collected from Cork, Ireland (n=19) where the water is fluoridated to a concentration between 0.8 and 1.0 mg/l; Knowsley, UK, where the water fluoride concentration is more...

  International Classification:

  Dental

  Categories:

  fluoride

  Geography:

  Republic of Ireland

  Community Dent Health, Vol: 19 Page: 12-7 March 2002
  C. E. Ketley; J. A. Cochran; M. A. Lennon; D. M. O'Mullane; H. V. Worthington

  [Preview] [Read]

• 9.   Urinary tract infection: an update on imaging strategies

  This article discusses reviews the role of radiology in urinary tract infections

  

  Abstract:

  Urinary tract infections (UTIs) are a common cause of morbidity in children. The distinction between upper and lower tract UTI is clinically difficult but important, as permanent renal damage can occur when the UTI involves the kidneys. Children with a history of UTI need investigated promptly and thoroughly. The goal of imaging in UTI is to aid in the diagnosis of acute pyelonephritis, more...

  Geography:

  Northern Ireland

  Eur Radiol, Vol: 14 Suppl 4 Page: L89-100 March 2004
  A. Paterson

  [Preview] [Read]

• 10.   Usage of paracetamol-containing combination analgesics remains high in primary care

  The aim of this study was to examine the prescribing patterns of the paracetamol-containing analgesics in Ireland

  

  Abstract:

  AIMS: Paracetamol-containing combination analgesics are widely prescribed but the use of paracetamol/dextropropoxyphene (co-proxamol) is particularly controversial. We aim to examine the prescribing patterns of the paracetamol-containing analgesics in Ireland. METHODS: A national primary care prescribing database was used to investigate patterns of usage. Twenty-six thousand three more...

  International Classification:

  Health service provision

  Categories:

  prescribing patterns

  Geography:

  Republic of Ireland

  Br J Clin Pharmacol, Vol: 60 Page: 648-52 December 2005
  C. Usher; M. Teeling; K. Bennett; B. McGowan; J. Feely

  [Preview] [Read]

• 11.   Use of a dynamic foot pressure index to monitor the effects of treatment for equinus gait in children with cerebral palsy

  This study examined use of a dynamic foot pressure index to monitor the effects of treatment for equinus gait in children with cerebral palsy

  

  Abstract:

  The purpose of this study is to introduce and describe a newly developed index using foot pressure analysis to quantify the degree of equinus gait in children with cerebral palsy before and after injection with botulinum toxin. Data were captured preinjection and 12 weeks postinjection. Ten children aged 2(1/2) to 6(1/2) years took part (5 boys and 5 girls). Three of them had a more...

  International Classification:

  Diseases of the nervous system - Cerebral palsy and other paralytic syndromes - cerebral palsy

  Categories:

  equinus gait

  Geography:

  Republic of Ireland

  J Pediatr Orthop, Vol: 27 Page: 288-94 2007 Apr-May
  D. Bennett; M. Walsh; R. O'Sullivan; J. Gallagher; T. O'Brien; C. J. Newman

  [Preview] [Read]

• 12.   Use of a food-consumption database with packaging information to estimate exposure to food-packaging migrants: expoxidized soybean oil and styrene monomer

  The aim of this study was to examine estimate exposure to two food-packaging migrants (expoxidized soybean oil (ESBO) and styrene monomer) using a food-consumption database that collected packaging information

  

  Abstract:

  There is no set protocol for completing refined exposure assessments of food-packaging migrants in the European Union. One novel method that could be used to provide more realistic exposure assessments and also reduce uncertainty in the exposure estimation could be the use of food consumption surveys that also have packaging information. The aim of the current study was to estimate more...

  International Classification:

  Other - exposure to food-packaging migrants

  Categories:

  exposure to food-packaging migrants

  Geography:

  Republic of Ireland

  Food Addit Contam, Vol: 24 Page: 216-25 February 2007
  E. Duffy; M. J. Gibney

  [Preview] [Read]

• 13.   Vaccination catch-up campaign in response to recent increase in Hib infection in Ireland

  This study reports on a vaccination catch up campaign in response to an increase in Hib infection in Ireland

  

  International Classification:

  Surveillance - Vaccinations

  Categories:

  Hib infection; vaccination catch up campaign

  Geography:

  Republic of Ireland

  Euro Surveill, Vol: 10 Page: E050929 2 September 2005
  M. Fitzgerald; M. Canny; D. O'Flanagan

  [Preview] [Read]

• 14.   Vaccination. HiB vaccine hits the wall

  The article discusses how the very success of the HiB vaccine seems to be contributing to a waning immunity to HiB disease in Ireland.

  

  Abstract:

  The very success of the HiB vaccine seems to be contributing to a waning immunity to HiB disease in Ireland. more...

  Geography:

  Republic of Ireland

  Nursing in the Community, Vol: 6 Page: 15-16 2005
  T. Horan

  [Preview] [Read]

• 15.   Variant Hirschsprung's disease

  This article discusses variant Hirschsprung's disease

  

  Abstract:

  Conditions that clinically resemble HD despite the presence of ganglion cells on suction rectal biopsy results, can be diagnosed by providing an adequate biopsy and employing a variety of histological techniques. Intestinal neuronal dysplasia is a distinct clinical entity that can be clearly proven histologically. Patients with IND not only have abnormalities of submucosal and myenteric more...

  Geography:

  Republic of Ireland

  Semin Pediatr Surg, Vol: 13 Page: 293-9 November 2004
  P. Puri; U. Rolle

  [Preview] [Read]

• 16.   Varicella outbreak in a residential home

  The aim of this study was to examine an outbreak of varicella in a residential home for 29 children(aged 4 to 16 years) with severe physical and learning disability

  

  Abstract:

  We report an outbreak of varicella in a residential home for 29 children(aged 4 to 16 years) with severe physical and learning disability. We report our group's incidence, complication and hospitalisation rate of varicella despite anti-viral therapy. As we did not have a control group we use statistics pertaining to the general population for comparison. All 15 non-immune children more...

  International Classification:

  Certain infectious and parasitic diseases - Viral infections characterized by skin and mucous membrane lesions - varicella

  Categories:

  varicella

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 99 Page: 133-5 May 2006
  F. Enright; B. Mc Mahon; A. Washington

  [Preview] [Read]

• 17.   Vascular outcome in patients with homocystinuria due to cystathionine beta-synthase deficiency treated chronically: a multicenter observational study

  The aim of this study was to examine the effectiveness of long-term homocysteine-lowering treatment in reducing vascular risk

  

  Abstract:

  An inborn error of metabolism, homocystinuria due to cystathionine beta-synthase deficiency, results in markedly elevated levels of circulating homocysteine. Premature vascular events are the main life-threatening complication. Half of all untreated patients have a vascular event by 30 years of age. We performed a multicenter observational study to assess the effectiveness of long-term more...

  International Classification:

  Other - homocysteine-lowering treatment

  Categories:

  homocysteine-lowering treatment;

  Geography:

  International

  Arterioscler Thromb Vasc Biol, Vol: 21 Page: 2080-5 December 2001
  S. Yap; G. H. Boers; B. Wilcken; D. E. Wilcken; D. P. Brenton; P. J. Lee; J. H. Walter; P. M. Howard; E. R. Naughten

  [Preview] [Read]

• 18.   Vascular trauma in an Irish regional hospital

  This study determined the incidence, aetiology, management and outcome of vascular injuries which required surgical intervention at a regional vascular unit

  

  Abstract:

  BACKGROUND: Vascular trauma is a common cause of mortality and morbidity worldwide. There are few accurate quantitative data available presently on the nature and outcome of these injuries. The aim of this study was to determine the incidence, aetiology, management and outcome of vascular injuries which required surgical intervention at a regional vascular unit. METHODS: All patients more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury

  Categories:

  vascular injuries

  Geography:

  Republic of Ireland

  Surgeon, Vol: 6 Page: 157-61 June 2008
  A. Abdulkarim; F. J. Fleming; E. G. Kavanagh; P. E. Burke; P. A. Grace

  [Preview] [Read]

• 19.   Verocytotoxin-producing Escherichia coli serotype O26:H11 outbreak in an Irish creche

  The aim of this study was to describe Verocytotoxin-producing Escherichia coli serotype O26:H11 outbreak in an Irish creche

  

  International Classification:

  Escherichia coli serotype O26:H11

  Categories:

  Verocytotoxin-producing Escherichia coli serotype O26:H11

  Geography:

  Republic of Ireland

  Eur J Clin Microbiol Infect Dis, Vol: 20 Page: 430-2 June 2001
  C. McMaster; E. A. Roch; G. A. Willshaw; A. Doherty; W. Kinnear; T. Cheasty

  [Preview] [Read]

• 20.   Vertebral fractures in boys with Duchenne muscular dystrophy

  The aim of this study was to examine the incidence of vertebral fractures particularly after initiation of corticosteroids

  

  Abstract:

  Osteoporosis causes significant morbidity for boys with Duchenne muscular dystrophy. Corticosteroid therapy given to prolong mobility may increase the rate of osteoporosis and risk of fracture. This study of 33 boys with Duchenne muscular dystrophy determined retrospectively the incidence of vertebral fractures particularly after initiation of corticosteroids. A latency period of 40 more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury

  Categories:

  vertebral fractures

  Geography:

  Northern Ireland

  Clin Pediatr (Phila), Vol: 42 Page: 353-6 May 2003
  J. E. Bothwell; K. E. Gordon; J. M. Dooley; J. MacSween; E. A. Cummings; S. Salisbury

  [Preview] [Read]

• 21.   Vesicoureteral reflux and ureteropelvic junction obstruction in children with horseshoe kidney: treatment and outcome

  This study determined the treatment and outcome of vesicoureteral reflux and ureteropelvic junction obstruction in children with horseshoe kidney

  

  Abstract:

  PURPOSE: Horseshoe kidney is the most common renal fusion anomaly. We determined the treatment and outcome of vesicoureteral reflux and ureteropelvic junction obstruction in children with horseshoe kidney. MATERIALS AND METHODS: We reviewed the medical and radiological records of 52 consecutive children, including 32 boys and 20 girls, in whom horseshoe kidney was diagnosed at 2 more...

  International Classification:

  Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux

  Categories:

  vesicoureteral reflux

  Geography:

  Republic of Ireland

  J Urol, Vol: 167 Page: 2566-8 June 2002
  S. Cascio; B. Sweeney; C. Granata; G. Piaggio; V. Jasonni; P. Puri

  [Preview] [Read]

• 22.   Visual impairment in childhood: insights from a community-based survey

  The aim of this study was to examine a profile of visual impairment in childhood with a view to informing future services and to raise awareness of the need for comprehensive assessment including developmental remediation and educational advice

  

  Abstract:

  BACKGROUND: The concept of visual impairment (VI) in childhood has changed over the last 30 years. There has been a decrease in the number of children with an isolated visual problem and an increase in the numbers with VI and coexisting neurological disability. This study aimed to produce a profile of VI in childhood with a view to informing future services and to raise awareness of the more...

  International Classification:

  Other - visual impairment

  Categories:

  visual impairment

  Geography:

  Northern Ireland

  Child Care Health Dev, Vol: 29 Page: 493-9 November 2003
  N. M. Flanagan; A. J. Jackson; A. E. Hill

  [Preview] [Read]

• 23.   Vitamin D in childhood and adolescence

  This article discusses Vitamin D in childhood and adolescence

  

  Abstract:

  It is well-established that prolonged and severe vitamin D deficiency leads to rickets in children and osteomalacia in adults. More marginal vitamin D deficiency is likely to be a significant contributing factor to osteoporosis risk. However, recent emerging data from studies of adults suggest that low vitamin D status (serum 25-hydroxyvitamin D levels <50 nmol/l) may be contributing to more...

  Geography:

  Republic of Ireland

  Postgrad Med J, Vol: 83 Page: 230-5 April 2007
  K. D. Cashman

  [Preview] [Read]

• 24.   Vitamins and minerals: a model for safe addition to foods

  This article discusses a model to estimate the level of each micronutrient that can be added safely to foods

  

  Abstract:

  BACKGROUND: Significant subgroups in most European populations have intakes below nationally recommended levels for several vitamins, minerals and trace elements, placing individuals at risk of suboptimal intake of important vitamins and minerals. The voluntary addition of micronutrients to the appropriate foods may help address the risks associated with low micronutrient intakes. more...

  Geography:

  Republic of Ireland

  Eur J Nutr, Vol: 42 Page: 118-30 April 2003
  A. Flynn; O. Moreiras; P. Stehle; R. J. Fletcher; D. J. Muller; V. Rolland

  [Preview] [Read]

• 25.   Vomiting bug on increase

  This article discusses the increase in rotavirus

  

  Abstract:

  Rotavirus is a significant burden on Ireland's health resources and its incidence is rising, reports Olivia Fens. more...

  Geography:

  Republic of Ireland

  World of Irish Nursing & Midwifery, Vol: 15 Page: 31-31 2007
  O. Fens

  [Preview] [Read]

• 26.   VRE in the Republic of Ireland: clinical significance, characteristics and molecular similarity of isolates

  The aim of this study was to describe vancomycin resistant enterococci in the Republic of Ireland

  

  Abstract:

  There have been increasing reports worldwide of vancomycin resistant enterococci (VRE) since they were first noted over ten years ago. This study sought to investigate the clinical significance of VRE in Ireland and to compare the phenotypic, genotypic and molecular characteristics of isolates recovered from patients in different institutions. The relative contribution of inter-hospital more...

  International Classification:

  Vancomycin resistant enterococci

  Categories:

  vancomycin resistant enterococci

  Geography:

  Republic of Ireland

  J Hosp Infect, Vol: 44 Page: 288-93 April 2000
  C. Nourse; C. Byrne; M. Kaufmann; C. T. Keane; L. Fenelon; E. G. Smyth; R. Hone; K. Butler

  [Preview] [Read]

• 27.   What a difference a vaccine makes

  The article discusses importance of immunisation programmes

  

  Abstract:

  While vaccination has been successful in bringing many diseases under control in Ireland, there is still no room for complacency, writes Siobham MacDermott. more...

  Geography:

  Republic of Ireland

  World of Irish Nursing & Midwifery, Vol: 14 Page: 47-48 2006
  S. MacDermott

  [Preview] [Read]

• 28.   What determines a patient's treatment? Evidence from out of hours primary care co-op data in the Republic of Ireland

  The aim of this study was to examine consistency in healthcare by considering the case study of individuals who present to out of hours primary care services in the Republic of Ireland with gastroenteritis

  

  Abstract:

  This study explores consistency in healthcare. It investigates whether vulnerable groups in the population receive the most appropriate care. This is achieved by considering the case study of individuals who present to out of hours (OOH) primary care services in the Republic of Ireland with gastroenteritis. Specifically an individual can potentially receive four services; nurse advice, more...

  International Classification:

  Health service provision

  Categories:

  consistency in healthcare

  Geography:

  Republic of Ireland

  Health Care Manag Sci, Vol: 10 Page: 283-92 September 2007
  G. Lordan

  [Preview] [Read]

• 29.   What influences physiotherapy use by children with cerebral palsy?

  The aim of this study was to examine factors that influence the frequency of physiotherapy currently used by a population of children with moderate to severe cerebral palsy

  

  Abstract:

  AIM: To investigate factors that influence the frequency of physiotherapy currently used by a population of children with moderate to severe cerebral palsy (CP). METHODS: A survey using a postal questionnaire was sent to 212 parents of children with moderate to severe CP. The families were identified from a geographically defined case register of children with CP in Northern Ireland more...

  International Classification:

  Diseases of the nervous system - Cerebral palsy and other paralytic syndromes - cerebral palsy

  Categories:

  physiotherapy; cerebral palsy

  Geography:

  Northern Ireland

  Child Care Health Dev, Vol: 30 Page: 151-60 March 2004
  J. Parkes; N. Hill; H. Dolk; M. Donnelly

  [Preview] [Read]

• 30.   Whole-body magnetic resonance imaging: a useful additional sequence in paediatric imaging

  The aim of this study was to describe the value of Whole-body MR imaging in ten children in whom this was added as an additional sequence when the primary diagnosis had not yet been made

  

  Abstract:

  BACKGROUND: Whole-body MR (WBMR) imaging allows the acquisition of images of the entire body in a matter of minutes. Its use has primarily been in the evaluation of possible metastases in the setting of a known primary tumour. OBJECTIVE: To document the value of WBMR imaging in ten children in whom this was added as an additional sequence when the primary diagnosis had not yet been more...

  International Classification:

  Procedure - Whole-body MR

  Categories:

  Whole-body MR

  Geography:

  Republic of Ireland

  Pediatr Radiol, Vol: 34 Page: 472-80 June 2004
  E. E. Laffan; R. O'Connor; S. P. Ryan; V. B. Donoghue

  [Preview] [Read]

• 31.   Wilms' tumor gene 1 (WT1) expression in childhood acute lymphoblastic leukemia: a wide range of WT1 expression levels, its impact on prognosis and minimal residual disease monitoring

  The aim of this study was to examine Wilm's tumor gene 1 expression patterns in childhood acute lymphoblastic leukemia

  

  Abstract:

  Wilms' tumor gene 1 (WT1) is overexpressed in the majority (70-90%) of acute leukemias and has been identified as an independent adverse prognostic factor, a convenient minimal residual disease (MRD) marker and potential therapeutic target in acute leukemia. We examined WT1 expression patterns in childhood acute lymphoblastic leukemia (ALL), where its clinical implication remains more...

  International Classification:

  Neoplasms - lymphoblastic leukemia

  Categories:

  Wilm's tumor gene 1 expression; -acute lymphoblastic leukemia

  Geography:

  International

  Leukemia, Vol: 20 Page: 254-63 February 2006
  L. Boublikova; M. Kalinova; J. Ryan; F. Quinn; A. O'Marcaigh; O. Smith; P. Browne; J. Stary; S. R. McCann; J. Trka; M. Lawler

  [Preview] [Read]

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