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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Child, Preschool

Your search returns 731 documents

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• 1.   Pharmaceutical prescribing for children. Part 6. Dental management and prescribing for the immunocompromised child

  This article the prescribing of medicines for children by dentists working in primary care

  

  Abstract:

  This paper is the sixth in a series on the prescribing of medicines for children by dentists working in primary care. It deals with the dental management and prescribing of medicines for the immunocompromised child. It differs from previous papers in the series in that, apart from the prescription of medicaments such as fluoride supplements and chlorhexidine mouthwashes, most medication more...

  Geography:

  Republic of Ireland

  Prim Dent Care, Vol: 13 Page: 135-9 October 2006
  P. Fleming; N. O. Palmer

  [Preview] [Read]

• 2.   Pharmacomechanical thrombectomy of acute deep vein thrombosis with the Trellis-8 isolated thrombolysis catheter

  This study evaluated the performance of the Trellis-8 isolated thrombolysis catheter during single-session pharmacomechanical thrombectomy combined with low-dose thrombolysis with tissue plasminogen activator in the treatment acute deep vein thrombosis

  

  Abstract:

  PURPOSE: To evaluate the performance of the Trellis-8 isolated thrombolysis catheter during single-session pharmacomechanical thrombectomy (PMT) combined with low-dose thrombolysis with tissue plasminogen activator (TPA) in the treatment of patients with acute deep vein thrombosis (DVT) and multiple comorbidities. MATERIALS AND METHODS: Retrospective analysis was performed of 19 more...

  International Classification:

  Procedure - treatment of acute deep vein thrombosis

  Categories:

  acute deep vein thrombosis

  Geography:

  Republic of Ireland

  J Vasc Interv Radiol, Vol: 18 Page: 715-24 June 2007
  G. J. O'Sullivan; D. G. Lohan; N. Gough; C. G. Cronin; S. T. Kee

  [Preview] [Read]

• 3.   Photopatch testing of 1155 patients: results of the U.K. multicentre photopatch study group

  This study aimed to photopatch testing using a group of sunscreen chemicals, defined indications and a standardized methodology including interpretation and relevance of reactions in patients

  

  Abstract:

  BACKGROUND: Photoallergic contact dermatitis can be difficult to diagnose if not appropriately investigated. Currently, the most common U.K. photoallergens appear to be sunscreen chemicals. The investigation of choice is photopatch testing (PPT), which is probably underused. In part, this is due to differences in methodology and results interpretation. OBJECTIVES: To conduct PPT using a more...

  International Classification:

  Other - eactions to sunscreen chemicals

  Categories:

  reactions to sunscreen chemicals

  Geography:

  International

  Br J Dermatol, Vol: 155 Page: 737-47 October 2006
  A. M. Bryden; H. Moseley; S. H. Ibbotson; M. M. Chowdhury; M. H. Beck; J. Bourke; J. English; P. Farr; I. S. Foulds; D. J. Gawkrodger; S. George; D. I. Orton; S. Shaw; J. McFadden; P. Norris; P. Podmore; S. Powell; L. E. Rhodes; J. Sansom; M. Wilkinson; H. van Weelden; J. Ferguson

  [Preview] [Read]

• 4.   Platelets in the paediatric population: the influence of age and the limitations of automation

  This study aimed to compare manual methodology and automated technologies; impedance, optical density and CD61 immunoplatelet method (available on the Cell Dyn 4000) with the reference method of flow cytometric analysis in a paediatric population

  

  Abstract:

  Accurate and precise platelet counting is important for the clinical management of children with platelet disorders. Current automated technologies are often unable to discriminate platelets from non-platelet particles particularly in circumstances where platelet anisocytosis is common. This study compares manual methodology and the automated technologies; impedance, optical density and more...

  International Classification:

  Effectiveness of measurement tool - optical density

  Categories:

  impedance; optical density; CD61 immunoplatelet; flow cytometric analysis

  Geography:

  Republic of Ireland

  Clin Lab Haematol, Vol: 27 Page: 250-7 August 2005
  P. Felle; C. McMahon; S. Rooney; P. Donnelly; F. Ni Chonchubhair

  [Preview] [Read]

• 5.   Play-wrestlers and their injuries

  The aim of this study was to examine the nature of injuries presenting at a paediatric fracture clinic in relation to children imitation of wrestlers seen on television

  

  Abstract:

  Television (TV) broadcast wrestling series have become very popular amongst Irish children in recent years. Over a four-month study period, 2.3% of injuries seen at a busy paediatric fracture clinic were attributable to play-wrestling. The mean age was 9.5 years (range 4-15 years). All of the children had been role-playing wrestlers and imitating wrestling "moves" seen on TV. more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury

  Categories:

  injuries

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 98 Page: 84 March 2005
  T. McCarthy; E. Crushell; K. Synnott; P. Kiely; D. McCormack

  [Preview] [Read]

• 6.   Pneumococcal conjugate vaccine

  This article discusses pneumococcal infections and development of an effective vaccine

  

  Abstract:

  Pneumococcal infections account for a significant proportion of bacterial infections in infants and children. The growing threat from pneumococci resistant to penicillin and other antimicrobials has led to increased pressure for the development of an effective vaccine. The only vaccine available until recently, a purified polysaccharide vaccine, is limited in that it fails to induce more...

  Categories:

  pneumococcal infections; vaccine

  Geography:

  Northern Ireland

  Curr Opin Pediatr, Vol: 13 Page: 70-4 February 2001
  M. Ledwith

  [Preview] [Read]

• 7.   Pneumococcal infection

  This article discusses pneumococcal infection

  

  Geography:

  Republic of Ireland

  World of Irish Nursing, Vol: 12 Page: 48-48 2004

  [Preview] [Read]

• 8.   Poisoning in a paediatric hospital

  The aim of this study was to examine poisoning cases presenting to a paediatric hospital.

  

  Abstract:

  BACKGROUND: Poisoning is a major cause of morbidity and mortality in children and adolescents. Pharmaceutical and household products are responsible for the majority of cases. AIM: To analyse poisoning cases presenting to a paediatric hospital. METHODS: A retrospective study of all poisoning cases presenting to the Accident and Emergency (A&E) department of one hospital over a more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - poisoning

  Categories:

  poisonings

  Geography:

  Republic of Ireland

  Ir J Med Sci, Vol: 172 Page: 78-80 2003 Apr-Jun
  F. Sharif; R. A. Khan; P. Keenan

  [Preview] [Read]

• 9.   Policy changes in breastfeeding guidelines

  This article discusses policy changes in breastfeeding guidelines in Ireland

  

  Geography:

  Republic of Ireland

  World of Irish Nursing, Vol: 11 Page: 43-43 2003

  [Preview] [Read]

• 10.   Polymorphisms within the vitamin B12 dependent methylmalonyl-coA mutase are not risk factors for neural tube defects

  The aim of this study was to examine polymorphisms within the vitamin B12 dependent methylmalonyl-coA mutase are not risk factors for neural tube defects

  

  Abstract:

  Methionine synthase and methylmalonyl-CoA mutase (mutase) are the only two known vitamin B(12) (B(12)) dependent enzymes in humans. A lower level of B(12) has been shown to be an independent maternal risk factor for neural tube defects (NTDs) prompting an investigation of common genetic variants within B(12) dependent enzymes. To investigate the role of methylmalonyl-CoA mutase variants more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - neural tube defects - condiction

  Categories:

  vitamin B12 dependent methylmalonyl-coA mutase; -neural tube defects

  Geography:

  Republic of Ireland

  Mol Genet Metab, Vol: 80 Page: 463-8 December 2003
  A. Parle-McDermott; E. J. McManus; J. L. Mills; V. B. O'Leary; F. Pangilinan; C. Cox; A. Weiler; A. M. Molloy; M. Conley; D. Watson; J. M. Scott; L. C. Brody; P. N. Kirke

  [Preview] [Read]

• 11.   Polyuria, polydipsia, polypopsia: "Mummy I want a drink"

  These case reports discuss three children with symptoms of polyuria, polydipsia, polypopsia

  

  International Classification:

  Endocrine, nutritional and metabolic diseases-Report

  Categories:

  polyuria, polydipsia, polypopsia

  Geography:

  Republic of Ireland

  Arch Dis Child Educ Pract Ed, Vol: 92 Page: ep139-43 October 2007
  M. Carr; D. Gill

  [Preview] [Read]

• 12.   Population differences in the International Multi-Centre ADHD Gene Project

  The aim of this study was to examine differences in the International Multi-Centre attention-deficit hyperactivity disorder Gene Project

  

  Abstract:

  The International Multi-Centre ADHD Gene sample consists of 674 families from eight countries (Belgium, England, Germany, Holland, Ireland, Israel, Spain, and Switzerland) ascertained from clinics for combined-type attention definity hyperactivity disorder in an offspring. 863 SNPs were successfully genotyped across 47 autosomal genes implicated in psychiatric disorders yielding a more...

  International Classification:

  Mental and behavioural disorders - Behavioural and emotional disorders with onset usually occurring in childhood and adolescence - attention-deficit hyperactivity disorder

  Categories:

  International Multi-Centre attention-deficit hyperactivity disorder Gene Project

  Geography:

  International

  Genet Epidemiol, Vol: 32 Page: 98-107 February 2008
  B. M. Neale; P. C. Sham; S. Purcell; T. Banaschewski; J. Buitelaar; B. Franke; E. Sonuga-Barke; R. Ebstein; J. Eisenberg; A. Mulligan; M. Gill; I. Manor; A. Miranda; F. Mulas; R. D. Oades; H. Roeyers; A. Rothenberger; J. Sergeant; H. C. Steinhausen; E. Taylor; M. Thompson; W. Chen; K. Zhou; P. Asherson; S. V. Faraone

  [Preview] [Read]

• 13.   Population-based survey of the relationship between energy efficiency during gait, functional ability and participation restriction in ambulatory children with cerebral palsy... Rehabilitation and Therapy Research Society Third Annual Conference: Collaborative research... making it a reality, held on 26-27 April 2007 at University of Ulster

  This abstract reports a population-based survey of the relationship between energy efficiency during gait, functional ability and participation restriction in ambulatory children with cerebral palsy

  

  Categories:

  energy efficiency; gait; functional ability; restriction in ambulatory children; cerebral palsy

  Geography:

  Northern Ireland

  Physical Therapy Reviews, Vol: 13 Page: 123-124 2008
  C. Kerr; B. C. McDowell; J. Parkes; A. P. Cosgrove

  [Preview] [Read]

• 14.   Possible association between passive smoking and lower exhaled nitric oxide in asthmatic children

  The aim of this study was to examine exposure to environmental tobacco smoke among asthmatic children and nonasthmatic controls

  

  Abstract:

  In adults, both active and passive smoking reduce levels of exhaled nitric oxide (eNO); however, to date, passive exposure to environmental tobacco smoke (ETS) has not been shown to affect eNO in children. The authors recruited 174 asthmatic children (96 male, 78 female) and 79 nonasthmatic controls (46 male, 33 female) from a group of children aged 5 to 14 yr who attended a children's more...

  International Classification:

  Diseases of the respiratory system - Chronic lower respiratory diseases - asthma

  Categories:

  environmental tobacco; asthma

  Geography:

  Northern Ireland

  Arch Environ Health, Vol: 58 Page: 613-6 October 2003
  T. J. Warke; V. Mairs; P. S. Fitch; M. Ennis; M. D. Shields

  [Preview] [Read]

• 15.   Postcataract surgery outcome in a series of infants and children with Down syndrome

  This study reported the visual and refractive outcome and complications in children with Down syndrome undergoing cataract extraction

  

  Abstract:

  AIMS: To report the visual and refractive outcome and complications in children with Down syndrome undergoing cataract extraction. METHODS: The case notes of 18 infants and children with lens opacities and Down syndrome who underwent cataract extraction between January 1981 and August 2006 were reviewed. RESULTS: Over the 25-year study period, 7% (33 eyes) of paediatric eyes undergoing more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Chromosomal abnormalities, not elsewhere classified - Down Syndrome

  Categories:

  children with Down syndrome undergoing cataract extraction

  Geography:

  Republic of Ireland

  Br J Ophthalmol, Vol: 92 Page: 1112-6 August 2008
  C. Gardiner; B. Lanigan; M. O'Keefe

  [Preview] [Read]

• 16.   Posterior fossa tumours in childhood: evaluation of presenting clinical features

  This study describes features associated with the presentation of posterior fossa tumours in childhood

  

  Abstract:

  A retrospective review was performed of the age profile and clinical features at presentation of 79 children with posterior fossa tumours. The mean age at presentation in this series (6.6 years) is consistent with a decreasing trend over the past 70 years. Headaches, ataxia and torticollis emerge as significant symptoms worthy of further investigation whilst abdominal pain and more...

  International Classification:

  Neoplasms - Malignant neoplasms - posterior fossa tumours

  Categories:

  posterior fossa tumours

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 94 Page: 52-3 February 2001
  D. F. O'Brien; J. Caird; M. Kennedy; G. A. Roberts; J. C. Marks; D. A. Allcutt

  [Preview] [Read]

• 17.   Potential viral pathogenic mechanism for new variant inflammatory bowel disease

  The aim of this study was to investigate the presence of persistent measles virus in the intestinal tissue of patients with new variant inflammatory bowel disease and controls

  

  Abstract:

  AIMS: A new form of inflammatory bowel disease (ileocolonic lymphonodular hyperplasia) has been described in a cohort of children with developmental disorder. This study investigates the presence of persistent measles virus in the intestinal tissue of these patients (new variant inflammatory bowel disease) and a series of controls by molecular analysis. METHODS: Formalin fixed, paraffin more...

  International Classification:

  Inflammatory bowel disease - Non specific

  Categories:

  measles virus; - inflammatory bowel disease

  Geography:

  Republic of Ireland

  Mol Pathol, Vol: 55 Page: 84-90 April 2002
  V. Uhlmann; C. M. Martin; O. Sheils; L. Pilkington; I. Silva; A. Killalea; S. B. Murch; J. Walker-Smith; M. Thomson; A. J. Wakefield; J. J. O'Leary

  [Preview] [Read]

• 18.   Potentiation of vincristine toxicity by itraconazole in children with lymphoid malignancies

  The aim of this study was to examine outcomes from concurrent administration of vincristine and intraconazole in children with lymphoid malignancies

  

  Abstract:

  Eight consecutive paediatric patients with acute lymphoblastic leukaemia (ALL) (n = 7) and T-cell non-Hodgkin's lymphoma (NHL) (n = 1) presenting within a 5-wk interval were started on a standard induction protocol which included weekly treatment with vincristine for 4 wk. Itraconazole was commenced as antifungal prophylaxis, 1-21 d after the first injection of vincristine. Within 2 to more...

  International Classification:

  Neoplasms - Malignant neoplasms - lymphoid malignancies

  Categories:

  lymphoid malignancies

  Geography:

  Republic of Ireland

  Acta Paediatr, Vol: 90 Page: 1204-7 October 2001
  M. Kamaluddin; P. McNally; F. Breatnach; A. O'Marcaigh; D. Webb; E. O'Dell; P. Scanlon; K. Butler; A. O'Meara

  [Preview] [Read]

• 19.   Prediction of in-hospital mortality by brain natriuretic peptide levels and other independent variables in acutely ill patients with suspected heart disease

  This study examined the ability of 11 continuous and 22 categorical variables, including brain natriuretic peptide levels measured at the time of admission, to predict in-hospital mortality

  

  Abstract:

  BACKGROUND: Brain natriuretic peptide (BNP) measurement can detect and assess heart failure. However, compared with traditional clinical parameters, its value for predicting the in-hospital mortality of patients with suspected heart disease has not been reported. STUDY DESIGN: Examination of the ability of 11 continuous and 22 categorical variables, including BNP levels measured at the more...

  International Classification:

  Diagnostic tool (biological measure) -in-hospital mortality

  Categories:

  brain natriuretic peptide; in-hospital mortality

  Geography:

  Republic of Ireland

  Can J Cardiol, Vol: 20 Page: 686-90 May 2004
  J. Kellett

  [Preview] [Read]

• 20.   Prediction of raised intracranial pressure complicating severe traumatic brain injury in children: implications for trial design

  This study aimed to describe current patterns of management of raised intracranial pressure in traumatic brain injury relevant to clinician buy-in to possible randomized controlled trials of treatments of raised ICP

  

  Abstract:

  OBJECTIVES: To describe current patterns of management of raised intracranial pressure (ICP) in traumatic brain injury relevant to clinician buy-in to possible randomized controlled trials of treatments of raised ICP. To examine the feasibility of early identification of children at sufficient risk of developing raised ICP to permit a uniform approach between centers to the initiation more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - traumatic brain injury

  Categories:

  raised intracranial pressure; traumatic brain injury

  Geography:

  Republic of Ireland and the United Kingdom

  Pediatr Crit Care Med, Vol: 9 Page: 8-14 January 2008
  R. J. Forsyth; R. C. Parslow; R. C. Tasker; C. A. Hawley; K. P. Morris

  [Preview] [Read]

• 21.   Preferential prescribing of oral corticosteroids in Irish male asthmatic children

  The aim of this study was to describe gender difference in the prescription of oral corticosteroids in asthmatic children

  

  Abstract:

  AIMS: To determine if there is a gender difference in the prescription of oral corticosteroids in asthmatic children (< 15 years). METHODS: 8072 asthmatics were identified on the basis that they received a prescription for either an inhaled beta-adrenoceptor agonist, an inhaled corticosteroid, inhaled cromoglycate/nedocromil sodium, oral xanthines or leukotriene antagonist. Odds ratios more...

  International Classification:

  Diseases of the respiratory system - Chronic lower respiratory diseases - asthma

  Categories:

  asthma

  Geography:

  Republic of Ireland

  Br J Clin Pharmacol, Vol: 52 Page: 319-21 September 2001
  D. Williams; A. Kelly; J. Feely

  [Preview] [Read]

• 22.   Prescribing patterns for asthma by general practitioners in six European countries

  This study aimed to examine current prescribing patterns for asthma by general practitioners in six European countries

  

  Abstract:

  To assess the level of concordance with international consensus on asthma management, we compared primary care prescribing patterns for asthma in different European countries. A prospective study of prescription items with an associated diagnostic label of asthma in patient consultations with a total of 235 general practitioners (GPs) from Belgium, England, Ireland, Italy, Northern more...

  International Classification:

  Practice/knowledge - asthma prescribing pattern

  Categories:

  asthma prescribing pattern

  Geography:

  International

  Respir Med, Vol: 94 Page: 578-83 June 2000
  G. Jepson; T. Butler; D. Gregory; K. Jones

  [Preview] [Read]

• 23.   Presence of multiple copies of the capsulation b locus in invasive Haemophilus influenzae type b (Hib) strains isolated from children with Hib conjugate vaccine failure

  The aim of this study was to verify whether amplification of invasive Haemophilus influenzae type b strains is involved in vaccine failure

  

  Abstract:

  Most invasive Haemophilus influenzae type b strains possess a duplication of the capsulation locus. Further amplification resulting in as many as 5 copies has been described. To verify whether amplification is involved in vaccine failure, the number of copies of the locus was determined by Southern blotting in 90 strains from children with true vaccine failure (TVF) between 1993 and more...

  International Classification:

  Vaccination

  Categories:

  haemophilus influenzae type b strains; - vaccine failure

  Geography:

  Republic of Ireland and the United Kingdom

  Journal of Infectious Diseases, Vol: 192 Page: 819-823 2005
  M. Cerquetti; R. Cardines; Ml; M. Giufré; A. Bella; T. Sofia; P. Mastrantonio; M. Slack

  [Preview] [Read]

• 24.   Prevalence and outcomes of childhood visual disorders

  The aim of this study was to examine the prevalence of childhood visual disorders: amblyopia (strabismus, refractive errors) and organic disease. It also assesses treatment outcomes, visual impairment and residual amblyopia

  

  Abstract:

  PURPOSE: This population-based study examines the prevalence of childhood visual disorders: amblyopia (strabismus, refractive errors) and organic disease. It also assesses treatment outcomes, visual impairment and residual amblyopia. METHODS: 1582 children were retrospectively analysed on treatment completion (age 8-9 years). Significant visual disorders included: esotropia, exotropia, more...

  International Classification:

  Diseases of the eye and adnexa - visual disorders

  Categories:

  childhood visual disorders; amblyopia; strabismus; refractive errors;

  Geography:

  Northern Ireland

  Ophthalmic Epidemiol, Vol: 12 Page: 243-50 August 2005
  U. M. Donnelly; N. M. Stewart; M. Hollinger

  [Preview] [Read]

• 25.   Prevalence of diarrhoea in the community in Australia, Canada, Ireland, and the United States

  This aim of this study was to examine determine prevalence of Diarrhoea in the community

  

  Abstract:

  BACKGROUND: Studies in several countries have estimated the prevalence of diarrhoea in the community. However, the use of different study designs and varying case definitions has made international comparisons difficult. METHODS: Similar cross-sectional telephone surveys were conducted in Australia, Canada, Ireland (including Northern Ireland), and the United States over 12 month more...

  International Classification:

  Certain infectious and parasitic diseases - Diarrhoea

  Categories:

  diarrhoea

  Geography:

  International

  Int J Epidemiol, Vol: 34 Page: 454-60 April 2005
  E. Scallan; S. E. Majowicz; G. Hall; A. Banerjee; C. L. Bowman; L. Daly; T. Jones; M. D. Kirk; M. Fitzgerald; F. J. Angulo

  [Preview] [Read]

• 26.   Prevalence of hepatitis B anti-core antibody in the Republic of Ireland

  The aim of this study was to examine the prevalence of hepatitis B exposure in the population of the Republic of Ireland, by measuring the prevalence of hepatitis B anti-core antibody in oral fluid collected by postal survey

  

  Abstract:

  The aim of this study was to estimate the prevalence of hepatitis B exposure in the population of the Republic of Ireland, by measuring the prevalence of hepatitis B anti-core antibody in oral fluid collected by postal survey. A random multi-stage stratified sample of Irish households was obtained, using the Irish electoral register as the sampling frame. A total of 962 households were more...

  International Classification:

  Certain infectious and parasitic diseases - Viral hepatitis - hepatitis B

  Categories:

  hepatitis C B anti-core antibody

  Geography:

  Republic of Ireland

  Epidemiol Infect, Vol: 125 Page: 701-4 December 2000
  T. O'Connell; L. Thornton; D. O'Flanagan; A. Staines; J. Connell; S. Dooley; G. McCormack

  [Preview] [Read]

• 27.   Prevalence of overweight and obesity in Irish school children, using four different definitions

  The aim of this study was to determine the prevalence of overweight and obesity in Irish children using four different weight-for-height methods and to examine secular trends from previous national data

  

  Abstract:

  OBJECTIVE: To determine the prevalence of overweight and obesity in Irish children using four different weight-for-height methods and to examine secular trends from previous national data. DESIGN: A cross-sectional survey. Weight and height were measured according to standard procedures and used to determine the prevalence of overweight and obesity using four weight-for-height methods more...

  International Classification:

  Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - obesity

  Categories:

  overweight; obesity

  Geography:

  Republic of Ireland

  Eur J Clin Nutr, Vol: 61 Page: 743-51 June 2007
  J. L. O'Neill; S. N. McCarthy; S. J. Burke; E. M. Hannon; M. Kiely; A. Flynn; M. A. Flynn; M. J. Gibney

  [Preview] [Read]

• 28.   Prevalence of overweight and obesity on the island of Ireland: results from the North South Survey of Children's Height, Weight and Body Mass Index, 2002

  The aim of this study was to examine the prevalence and correlates of overweight and obesity among children and adolescents in the Republic of Ireland (RoI) and Northern Ireland (NI).

  

  Abstract:

  BACKGROUND: Childhood obesity is emerging as a major public health problem in developed and developing countries worldwide. The aim of this survey was to establish baseline data on the prevalence and correlates of overweight and obesity among children and adolescents in the Republic of Ireland (RoI) and Northern Ireland (NI). METHODS: The heights and weights of 19,617 school-going more...

  International Classification:

  Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - obesity

  Categories:

  overweight; obesity

  Geography:

  Northern Ireland and the Republic of Ireland

  BMC Public Health, Vol: 7 Page: 187 2007
  H. Whelton; J. Harrington; E. Crowley; V. Kelleher; M. Cronin; I. J. Perry

  [Preview] [Read]

• 29.   Primary care utilisation rates in pre-school children

  This study examined primary care utilisation rates in pre-school children

  

  Abstract:

  A key objective of the Lifeways cross generation cohort study is to examine health and healthcare, according to socio-economic indicators, during the first five years of life. GP contact details were available for 1032 children. 772 GPs in 589 practices were approached and data were obtained on 640 children (59% of original cohort). The mean follow-up time was 3.0 years (95% CI more...

  International Classification:

  Longitudinal - Health service provision

  Categories:

  primary care utilisation rates

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 100 Page: suppl 23-7 September 2007
  U. B. Fallon; A. W. Murphy; E. Majawit; C. O'Riordan; G. Bury; D. O'Mahony; C. C. Kelleher

  [Preview] [Read]

• 30.   Primary desmoplastic small round cell tumor of bone: report of a case with cytogenetic confirmation

  This case report discusses a case of desmoplastic small round cell tumor occurring in the right ilium of a 13-year-old boy

  

  Abstract:

  We report a case of desmoplastic small round cell tumor occurring in the right ilium of a 13-year-old boy. Morphologically, the neoplasm consisted of small round cells of primitive appearance with a diffuse growth pattern replacing marrow space and eroding bone. Immunohistochemical staining was positive for vimentin, synapsin, CD99 (MIC2 protein), and FLI-1, prompting an initial more...

  International Classification:

  ICD-O:Connective/soft tissue tumors and sarcomas (ICD-O 8800-9059)

  Categories:

  desmoplastic small round cell tumor

  Geography:

  Republic of Ireland

  Cancer Genet Cytogenet, Vol: 156 Page: 167-71 January 2005
  A. Murphy; R. L. Stallings; J. Howard; M. O'Sullivan; R. Hayes; F. Breatnach; M. B. McDermott

  [Preview] [Read]

• 31.   Primary immunodeficiency disorders in the Republic of Ireland: first report of the national registry in children and adults

  The aim of this study was to examine findings from the national registry on primary immunodeficiency disorders in the Republic of Ireland

  

  Abstract:

  Data collection for the national registry for patients with primary immunodeficiency disorders in the Republic of Ireland commenced in 1996. One hundred and fifteen cases of primary immunodeficiency diseases were registered between December 1996 and February 2003. The most frequent primary immunodeficiency disorders were antibody deficiency (n = 53) and complement deficiency (n = 32). more...

  International Classification:

  Immunology - primary immunodeficiency disorders

  Categories:

  primary immunodeficiency disorders

  Geography:

  Republic of Ireland

  J Clin Immunol, Vol: 25 Page: 73-7 January 2005
  M. Abuzakouk; C. Feighery

  [Preview] [Read]

• 32.   Primary middle-ear lymphoma in a child

  This case report discusses a case of a five year old boy who presented with a lower motor neurone facial nerve palsy secondary to primary non-Hodgkin's lymphoma of the middle ear

  

  Abstract:

  The case of a five year old boy who presented with a lower motor neurone facial nerve palsy secondary to primary non-Hodgkin's lymphoma (NHL) of the middle ear is discussed. Any child who presents with a facial nerve palsy and conductive hearing loss requires thorough evaluation to exclude the possibility of temporal bone malignancy. more...

  International Classification:

  Neoplasm - Report

  Categories:

  primary non-Hodgkin's lymphoma

  Geography:

  Republic of Ireland

  J Laryngol Otol, Vol: 117 Page: 205-7 March 2003
  E. E. Lang; R. M. Walsh; M. Leader

  [Preview] [Read]

• 33.   Primary tooth fluorosis in 5-year-old schoolchildren in Ireland

  The aim of this study was to examine the prevalence of primary tooth fluorosis in the dentitions of 5-year-old schoolchildren

  

  Abstract:

  AIM: This was to determine the prevalence of primary tooth fluorosis in the dentitions of 5-year-old schoolchildren. A subsidiary aim was to investigate whether an association existed between the presence of primary tooth fluorosis, fluoridation status, infant feeding practices or the oral hygiene practices of the child. STUDY DESIGN: A cross-sectional and stratified by fluoridation more...

  International Classification:

  Dental

  Categories:

  primary tooth fluorosis

  Geography:

  Republic of Ireland

  Eur J Paediatr Dent, Vol: 6 Page: 155-61 September 2005
  M. A. Harding; H. Whelton; D. M. O'Mullane; M. Cronin; J. J. Warren

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• 34.   Prophylactic thyroidectomy in the treatment of thyroid medullary carcinoma. Age for surgery?

  The aim of this study was to describe prophylactic thyroidectomy in the treatment of thyroid medullary carcinoma

  

  Abstract:

  Since the association of RET proto-oncogene mutations and medullary thyroid carcinoma in children there has been much discussion regarding timing of surgery. Our study group was formed from a brother and sister (8 and 5) and 3 brothers (9, 13, 16) selected on the basis of a positive family history for thyroid medullary carcinoma. Histological examinations of the thyroidectomy specimens more...

  International Classification:

  Neoplasms - Malignant neoplasms - thyroid medullary carcinoma

  Categories:

  Prophylactic thyroidectomy; thyroid medullary carcinoma

  Geography:

  Republic of Ireland

  Eur J Pediatr Surg, Vol: 10 Page: 334-6 October 2000
  S. Hassett; C. Costigan; M. McDermott; R. J. Fitzgerald

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• 35.   Prospective study of use of perioperative antimicrobial therapy in general surgery

  This study examined the use of perioperative antimicrobial therapy in general surgery

  

  Abstract:

  BACKGROUND: Perioperative antimicrobial therapy has demonstrated efficacy in reducing the rate of surgical site infections in clinical trials. With the emergence of antibiotic resistance, the risk of reaction, and the inevitable financial repercussions, use of prophylactic antibiotics is not a panacea, and their misuse may have considerable implications. The aim of this study was to more...

  International Classification:

  Procedure - perioperative antimicrobial therapy

  Categories:

  perioperative antimicrobial therapy

  Geography:

  Republic of Ireland

  Surg Infect (Larchmt), Vol: 7 Page: 355-60 August 2006
  B. G. Fennessy; M. J. O'Sullivan; G. J. Fulton; W. O. Kirwan; H. P. Redmond

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• 36.   Prospective survey of childhood inflammatory bowel disease in the British Isles

  The aim of this study was to examine the incidence of childhood inflammatory bowel disease in the British Isles

  

  Abstract:

  The incidence of inflammatory bowel disease in children in western countries may be rising. Since there is no prospective national data on the incidence of inflammatory bowel disease in the UK and Republic of Ireland (ROI), we undertook a prospective survey to determine this incidence. The incidence during 1998 and 1999 was 5.2/100,000 per year in children aged younger than 16 years. more...

  International Classification:

  Other - Inflammatory bowel disease - non specific

  Categories:

  inflammatory bowel disease

  Geography:

  Republic of Ireland and the United Kingdom

  Lancet, Vol: 357 Page: 1093-4 April 2001
  A. Sawczenko; B. K. Sandhu; R. F. Logan; H. Jenkins; C. J. Taylor; S. Mian; R. Lynn

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• 37.   Proteomic analysis of recurrent joint inflammation in juvenile idiopathic arthritis

  The aim of the study was to examine synovial fluid proteome in juvenile idiopathic arthritis to isolate joint-specific biomarkers that are expressed in patients displaying recurrent joint inflammation.

  

  Abstract:

  The synovial fluid proteome in juvenile idiopathic arthritis was investigated to isolate joint-specific biomarkers that are expressed in patients displaying recurrent joint inflammation. To identify the synovial specific proteome, matched synovial fluid and plasma samples were subjected to protein separation by 2-dimension electrophoresis (2DE). Forty-three protein spots, overexpressed more...

  International Classification:

  Diseases of the musculoskeletal system and connective tissue - Arthropathies - arthritis

  Categories:

  uvenile idiopathic arthritis

  Geography:

  Northern Ireland

  J Proteome Res, Vol: 5 Page: 1988-95 August 2006
  D. S. Gibson; S. Blelock; S. Brockbank; J. Curry; A. Healy; C. McAllister; M. E. Rooney

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• 38.   Pupillary autonomic denervation with increasing duration of diabetes mellitus

  The aim of this study was to compare the autonomic pupillary changes in type I and II diabetic patients without clinical evidence of diabetic autonomic neuropathy with age matched controls

  

  Abstract:

  BACKGROUND/AIMS: The autonomic pupillary changes in type I and II diabetic patients without clinical evidence of diabetic autonomic neuropathy (DAN) were compared with age matched controls. The relation between pupillary and cardiovascular autonomic function was assessed in the diabetic patients. METHODS: A case-control study was performed with diabetics grouped according to type and more...

  International Classification:

  Endocrine, nutritional and metabolic diseases - diabetic occular changes

  Categories:

  autonomic pupillary changes; -diabetic patients

  Geography:

  Republic of Ireland

  Br J Ophthalmol, Vol: 85 Page: 1225-30 October 2001
  M. Cahill; P. Eustace; V. de Jesus

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• 39.   Rabbit antithymocyte globulin as induction immunotherapy for pediatric deceased donor kidney transplantation

  This study studied the long-term results and safety of antithymocyte globulin as induction immunotherapy in all children undergoing transplantation at our institution since 1991

  

  Abstract:

  PURPOSE: There is scant literature describing the long-term outcome of the use of antithymocyte globulin induction immunotherapy in pediatric deceased donor kidney transplants. We retrospectively studied the long-term results and safety of antithymocyte globulin as induction immunotherapy in all children undergoing transplantation at our institution since 1991. MATERIALS AND METHODS: A more...

  International Classification:

  Organ transplants

  Categories:

  antithymocyte globulin as induction immunotherapy; -organ transplants

  Geography:

  Republic of Ireland

  J Urol, Vol: 174 Page: 703-7 August 2005
  M. H. Kamel; P. Mohan; D. M. Little; A. Awan; D. P. Hickey

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• 40.   Rabbit antithymocyte globulin related decrease in platelet count reduced risk of pediatric renal transplant graft thrombosis

  The aim of the study was to compare the potential protective effect for the decrease in platelet count associated with RATG therapy against pediatric renal transplant graft vascular thrombosis

  

  Abstract:

  Graft thrombosis is a serious complication in pediatric renal transplantation. We assess a potential protective effect for the decrease in platelet count associated with RATG therapy against pediatric renal transplant graft vascular thrombosis. Between January 1986 and December 1998, 120 kidney transplants were performed in 95 pediatric recipients. Patients were divided into two groups. more...

  International Classification:

  Organ transplants

  Categories:

  renal transplant graft vascular thrombosis

  Geography:

  Republic of Ireland

  Pediatr Transplant, Vol: 10 Page: 816-21 November 2006
  M. H. Kamel; P. Mohan; P. J. Conlon; D. M. Little; P. O'Kelly; D. P. Hickey

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• 41.   Radiological findings in cyclical administration of intravenous pamidronate in children with osteoporosis

  This case report discusses radiological findings in cyclical administration of intravenous pamidronate in children with osteoporosis

  

  International Classification:

  Diseases of the musculoskeletal system and connective tissue - Report

  Categories:

  osteoporosis

  Geography:

  Republic of Ireland

  Arch Dis Child, Vol: 92 Page: 1087 December 2007
  C. Onwuneme; K. Abdalla; N. Cassidy; O. Hensey; S. Ryan

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• 42.   Rapid-onset dystonia-parkinsonism: a clinical and genetic analysis of a new kindred

  The aim of this study was to describe the clinical, psychiatric, and genetic features of rapid-onset dystonia-parkinsonism from three generations of an Irish family

  

  Abstract:

  BACKGROUND: Rapid-onset dystonia-parkinsonism (RDP) is an autosomal dominant disorder linked to chromosome 19q13 that is characterized by sudden onset of primarily bulbar and upper limb dystonia with parkinsonism. METHODS: The authors evaluated 12 individuals from three generations of an Irish family and obtained detailed medical records on a deceased member. The authors describe the more...

  International Classification:

  Diseases of the nervous system - Extrapyramidal and movement disorders - dystonia-parkinsonism

  Categories:

  dystonia-parkinsonism

  Geography:

  Republic of Ireland

  Neurology, Vol: 55 Page: 991-5 October 2000
  S. J. Pittock; C. Joyce; V. O'Keane; B. Hugle; M. O. Hardiman; F. Brett; A. J. Green; D. E. Barton; M. D. King; D. W. Webb

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• 43.   Rasmussen's syndrome associated with chronic brain stem encephalitis

  This case report discusses a 3-year-old boy with a clinical picture of Rasmussen's encephalitis who had clinical, radiological and pathological evidence of brain stem involvement resulting in death

  

  Abstract:

  We report a 3-year-old boy with a clinical picture of Rasmussen's encephalitis who had clinical, radiological and pathological evidence of brain stem involvement resulting in death. In addition, there were unexpected neuropathological findings of severe bilateral mesial temporal sclerosis. We discuss the novel finding of brain stem involvement in this condition and the association with more...

  International Classification:

  Diseases of the nervous system - Report

  Categories:

  Rasmussen's encephalitis

  Geography:

  Republic of Ireland

  Eur J Paediatr Neurol, Vol: 5 Page: 203-6 2001
  D. McDonald; Farrell; J. McMenamin

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• 44.   Reasons for referral of children to a general anaesthetic service in Northern Ireland

  The aim of this study was to investigate dental practitioner's clinical and social reasons for referral of children for dental extractions under general anaesthesia and to relate these to separately obtained information

  

  Abstract:

  OBJECTIVE: To investigate, in a case-specific manner, dental practitioners' clinical and social reasons for referral of children for dental extractions under general anaesthesia and to relate these to separately obtained information. DESIGN: For each child referred to the community general anaesthetic dental extraction service, closed-ended questionnaires were completed by the referring more...

  International Classification:

  Dental

  Categories:

  dental extractions; anaesthesia

  Geography:

  Northern Ireland

  Int J Paediatr Dent, Vol: 8 Page: 191-6 September 1998
  C. MacCormac; M. Kinirons

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• 45.   Recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high responding inhibitors

  This study examined the use of recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high responding inhibitors

  

  Abstract:

  The management of acute and surgical bleeding episodes in children with severe factor VIII or IX deficiency who develop high responding inhibitors presents a major therapeutic challenge to clinicians. Recombinant factor VIIa (rVIIa) is an effective, reliable and safe treatment that can be used to treat acute bleeding episodes prior to commencing an immune tolerance programme and to more...

  International Classification:

  Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - Coagulation defects, purpura and other haemorrhagic conditions - haemophilia

  Categories:

  haemophilia

  Geography:

  Republic of Ireland and the United Kingdom

  Br J Haematol, Vol: 116 Page: 632-5 March 2002
  N. O'Connell; C. Mc Mahon; J. Smith; K. Khair; I. Hann; R. Liesner; O. P. Smith

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• 46.   Recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high-responding inhibitors

  This study examined recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high-responding inhibitors

  

  Abstract:

  The development of inhibitors to therapeutic factor concentrates in children with haemophilia A or B is a troublesome complication of factor replacement therapy. Immune tolerance protocols have been developed to eliminate the inhibitors, and these are successful in approximately 80% of children. However, acute bleeding episodes require treatment with a factor (F)VIII or FIX bypassing more...

  International Classification:

  Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - Coagulation defects, purpura and other haemorrhagic conditions - haemophilia

  Categories:

  haemophilia

  Geography:

  Republic of Ireland

  Pathophysiol Haemost Thromb, Vol: 32 Suppl 1 Page: 22-5 2002
  O. P. Smith

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• 47.   Recruitment bias in a population-based study of children with cerebral palsy

  The aim of this study was to examine recruitment bias in a population-based study of locomotor ability in children with cerebral palsy

  

  Abstract:

  OBJECTIVE: The purpose of this analysis was to assess recruitment bias in a population-based study of locomotor ability in children with cerebral palsy. METHOD: A population-based case register was used as a sampling frame and was considered a highly ascertained record of children with the condition. A twin track approach to recruitment for the Locomotor Study was adopted through: (1) a more...

  International Classification:

  Gait

  Categories:

  locomotor ability

  Geography:

  Northern Ireland

  Pediatrics, Vol: 118 Page: 1616-22 October 2006
  J. Parkes; C. Kerr; B. C. McDowell; A. P. Cosgrove

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• 48.   Rectal hydrocortisone during vomiting in children with adrenal insufficiency

  This study evaluates rectal hydrocortisone as an emergency glucocorticoid replacement therapy in adrenal insufficient children

  

  Abstract:

  AIM: To evaluate rectal hydrocortisone as an emergency glucocorticoid replacement therapy in adrenal insufficient children. METHODS: A parental questionnaire evaluated preferred treatment, problems or benefits of i.m. and rectal hydrocortisone, frequency and indications for administration and who administered treatment. Admissions of children with adrenal insufficiency were monitored. more...

  International Classification:

  Health service provision

  Categories:

  adrenal insufficient; glucocorticoid replacement therapy

  Geography:

  Republic of Ireland

  J Pediatr Endocrinol Metab, Vol: 16 Page: 1101-4 2003 Oct-Nov
  M. Ni Chroinin; M. Fallon; D. Kenny; S. Moriarty; H. Hoey; C. Costigan

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• 49.   Reflux nephropathy in infancy: a comparison of infants presenting with and without urinary tract infection

  This study compared the incidence of renal scarring in infants with high grade vesicoureteral reflux in those presenting with and without urinary tract infection

  

  Abstract:

  PURPOSE: We compared the incidence of renal scarring in infants with high grade vesicoureteral reflux in those presenting with and without urinary tract infection. METHODS AND METHODS: We reviewed the medical records of 81 male and 46 female infants (194 renal refluxing units) with a mean age of 4 months who had grade IV or V primary vesicoureteral reflux and underwent an anti-reflux more...

  International Classification:

  Diseases of the genitourinary system - Renal tubulo-interstitial diseases - vesicoureteric reflux

  Categories:

  vesicoureteral reflux

  Geography:

  Republic of Ireland

  J Urol, Vol: 166 Page: 648-50 August 2001
  B. Sweeney; S. Cascio; M. Velayudham; P. Puri

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• 50.   Regional differences in overweight: an effect of people or place?

  The aim of the study was to examine the United Kingdom country and English regional differences in childhood overweight (including obesity) at 3 years and determine whether any differences persist after adjustment for individual risk factors

  

  Abstract:

  OBJECTIVE: To examine UK country and English regional differences in childhood overweight (including obesity) at 3 years and determine whether any differences persist after adjustment for individual risk factors. DESIGN: Nationally representative prospective study. SETTING: England, Wales, Scotland and Northern Ireland. PARTICIPANTS: 13 194 singleton children from the UK Millennium more...

  International Classification:

  Endocrine, nutritional and metabolic disease - Obesity and other hyperalimentation - obesity

  Categories:

  overweight; obesity

  Geography:

  the United Kingdom

  Arch Dis Child, Vol: 93 Page: 407-13 May 2008
  S. S. Hawkins; L. J. Griffiths; T. J. Cole; C. Dezateux; C. Law

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• 51.   Relation between objectively measured feeding competence and nutrition in children with cerebral palsy

  The aim of this study was to examine the prevalence of undernutrition in children with cerebral palsy and to determine the relation with feeding ability

  

  Abstract:

  This study aimed to investigate the prevalence of undernutrition in children with cerebral palsy (CP) and to determine the relation with feeding ability. Ninety children with CP from special needs schools were examined. Undernutrition was diagnosed on one or more of the following criteria: weight <2nd centile, triceps or subscapular skinfold measurement <3rd centile, mid-arm more...

  International Classification:

  Diseases of the nervous system - Cerebral palsy and other paralytic syndromes - cerebral palsy

  Categories:

  undernutrition; cerebral palsy

  Geography:

  Northern Ireland

  Dev Med Child Neurol, Vol: 43 Page: 187-90 March 2001
  K. E. Troughton; A. E. Hill

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