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Irish Child Health Database - Peer Reviewed Papers

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Animals

Your search returns 124 documents

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  • 1.   Administration of antenatal glucocorticoids upregulates peptide growth factor gene expression in nitrofen-induced congenital diaphragmatic hernia in rats

    The aim of this study was to investigate antenatal glucocorticoids administration effect on gene expression of basic fibroblast growth factor, platelet-derived growth factor transforming growth factor-beta1 in congenital diaphragmatic hernia

    J Pediatr Surg, Vol: 35 Page: 109-12 January 2000
    T. Oue; H. Shima; Y. Taira; P. Puri

    [Preview] [Read]

  • 2.   Adriamycin effects on the chick embryo

    The aim of this study was to test the hypothesize that administration of adriamycin to chick embryos would cause similar anomalies to the vertebral, anorectal, cardiac, tracheoesophageal, renal, limb anomalies association seen in the Adriamycin rat mode

    Pediatr Surg Int, Vol: 19 Page: 359-64 July 2003
    A. Mortell; J. Giles; J. Bannigan; P. Puri

    [Preview] [Read]

  • 3.   Adriamycin induces notochord hypertrophy with conservation of sonic hedgehog expression in abnormal ectopic notochord in the adriamycin rat model

    The aim of this study was to test the hypothesis that Shh-expressing ectopic notochord could contribute to an increased volume of notochord relative to total embryo volume, resulting in an increased concentration of Shh in the notochord of embryos

    J Pediatr Surg, Vol: 39 Page: 859-63 June 2004
    A. Mortell; A. M. O'Donnell; S. Giles; J. Bannigan; P. Puri

    [Preview] [Read]

  • 4.   Airway proteins--surfactants

    This article discusses the airway proteins - surfactants

    Pediatr Pulmonol Suppl, Vol: 26 Page: 143-6 2004
    H. L. Halliday

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  • 5.   Alterations in cholinergic and neuropeptide innervation of urinary bladder following partial bladder outlet obstruction

    The aim of this study was to test the hypothesize that the functional changes in the bladder following bladder outlet obstruction are due to alteration in cholinergic and sensory neuropeptide innervation

    Pediatr Surg Int, Vol: 19 Page: 427-31 August 2003
    B. Chertin; U. Rolle; S. Cascio; P. Puri

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  • 6.   Altered expression of angiotensin II receptor subtypes and transforming growth factor-beta in the heart of nitrofen-induced diaphragmatic hernia in rats

    The aim of this study was to determine the expression of Ag-II receptor subtypes and TGF-beta1 in the hypoplastic heart of nitrofen-induced congenital diaphragmatic hernia

    Pediatr Surg Int, Vol: 21 Page: 148-52 March 2005
    H. Teramoto; M. Shinkai; P. Puri

    [Preview] [Read]

  • 7.   Altered gene level expression of thyroid hormone receptors alpha-1 and beta-1 in the lung of nitrofen-induced diaphragmatic hernia

    The aim of this study was to investigate gene level expression of TR-alpha1 and TR-beta1 in the lung of nitrofen-induced congenital diaphragmatic hernia using reverse transcription polymerase chain reaction (RT-PCR)

    J Pediatr Surg, Vol: 36 Page: 1675-8 November 2001
    H. Teramoto; N. Guarino; P. Puri

    [Preview] [Read]

  • 8.   Altered renin-angiotensin system gene expression causes renal hypoplasia in the rats with nitrofen-induced diaphragmatic hernia

    The aim of this study was to test the hypothesize that abnormal expression of renin-angiotensin system components may be responsible for renal hypoplasia in congenital diaphragmatic hernia

    Pediatr Surg Int, Vol: 22 Page: 57-60 January 2006
    B. Chertin; N. Nakazawa; S. Montedonico; H. Shima; P. Puri

    [Preview] [Read]

  • 9.   Animal models in pediatric surgery

    This article discusses animal models in pediatric surgery

    Pediatr Surg Int, Vol: 22 Page: 111-28 February 2006
    A. Mortell; S. Montedonico; P. Puri

    [Preview] [Read]

  • 10.   Antenatal dexamethasone administration increases fetal lung DNA synthesis and RNA and protein content in nitrofen-induced congenital diaphragmatic hernia in rats

    The aim of this study was to investigate the effect of antenatal glucocorticoid administration on DNA synthesis and RNA and protein content in nitrofen-induced congenital diaphragmatic hernia in rats

    Pediatr Res, Vol: 48 Page: 789-93 December 2000
    T. Oue; H. Shima; N. Guarino; P. Puri

    [Preview] [Read]

  • 11.   Antenatal dexamethasone administration inhibits smooth-muscle-cell DNA synthesis in pulmonary-arterial media in nitrofen-induced congenital diaphragmatic hernia in rats

    The aim of this study was to investigate the effect of antenatal glucocorticoid therapy on smooth-muscle-cell DNA synthesis in the pulmonary arteries in a nitrofen-induced congenital diaphragmatic hernia rat model following nitrofen admin

    Pediatr Surg Int, Vol: 16 Page: 414-6 2000
    Y. Taira; H. Shima; E. Miyazaki; K. Ohshiro; P. Puri

    [Preview] [Read]

  • 12.   Antenatal dexamethasone enhances endothelin receptorB expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats

    The aim of this study was to evaluate the effect of antenatal glucocorticoid administration on ET-1 system in nitrofen-induced congenital diaphragmatic hernia hypoplastic lung in rats

    J Pediatr Surg, Vol: 35 Page: 203-7 February 2000
    H. Shima; T. Oue; Y. Taira; E. Miyazaki; P. Puri

    [Preview] [Read]

  • 13.   Antenatal dexamethasone enhances endothelin-1 synthesis and gene expression in the heart in congenital diaphragmatic hernia in rats

    The aim of this study was to determine cardiac gene expression of ET-1 and of its receptor ET(A) and the cardiac ET-1 content in the heart of nitrofen-induced congenital diaphragmatic hernia in rats and evaluate antenatal Dexamethason treatment effects

    J Pediatr Surg, Vol: 37 Page: 1563-7 November 2002
    N. Guarino; P. Puri

    [Preview] [Read]

  • 14.   Antenatal dexamethasone enhances surfactant protein synthesis in the hypoplastic lung of nitrofen-induced diaphragmatic hernia in rats

    The aim of this study was to investigate whether maternal administration of dexamethasone has any effect on the expression of surfactant protein A and surfactant protein B in nitrofen-induced experimental congenital diaphragmatic hernia rat model

    J Pediatr Surg, Vol: 35 Page: 1468-73 October 2000
    N. Guarino; T. Oue; H. Shima; P. Puri

    [Preview] [Read]

  • 15.   Antenatal dexamethasone improves atrial natriuretic peptide receptors in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats

    The aim of this study was to investigate the effect of antenatal glucocorticoid administration on the atrial natriuretic peptide system in nitrofen-induced congenital diaphragmatic hernia hypoplastic lung in rats.

    Pediatr Surg Int, Vol: 16 Page: 252-5 2000
    H. Shima; N. Guarino; P. Puri

    [Preview] [Read]

  • 16.   Anti-epileptic drugs in pregnancy: current safety and other issues

    This article discusses the need for women with epilepsy to both take their medication but also consider the effect of anti-epileptic drugs on their developing fetus

    Expert Opin Pharmacother, Vol: 4 Page: 445-56 April 2003
    J. I. Morrow; J. J. Craig

    [Preview] [Read]

  • 17.   Antigastric autoantibodies in ferrets naturally infected with Helicobacter mustelae

    The aim of this study was to investigate whether molecular mimicry by Helicobacter mustelae causes autoantibodies in infected ferrets

    Infect Immun, Vol: 69 Page: 2708-13 April 2001
    T. O. Croinin; M. Clyne; B. J. Appelmelk; B. Drumm

    [Preview] [Read]

  • 18.   Baculovirus expression of parvovirus B19 (B19V) NS1: utility in confirming recent infection

    The aim of this study was to elucidate the role of anti-B19V NS1 (anti-parvovirus B19 ) antibody detection in recent infection, full-length B19V NS1 was expressed and purified

    J Clin Virol, Vol: 22 Page: 55-60 August 2001
    O. Ennis; A. Corcoran; K. Kavanagh; B. P. Mahon; S. Doyle

    [Preview] [Read]

  • 19.   Basis of the superiority of cefoperazone amphotericin teicoplanin for isolating Campylobacter upsaliensis from stools

    The aim of the study was to compare the basis of the superiority of cefoperazone amphotericin teicoplanin for isolating Campylobacter upsaliensis from stools

    J Clin Microbiol, Vol: 39 Page: 2713-6 July 2001
    C. Byrne; D. Doherty; A. Mooney; M. Byrne; D. Woodward; W. Johnson; F. Rodgers; B. Bourke

    [Preview] [Read]

  • 20.   Bilateral megaureters in the Adriamycin rat model

    The aim of this study was to test the hypothesis that Adriamycin administration during a particular time frame could yield a high incidence of urinary tract anomalies

    Pediatr Surg Int, Vol: 21 Page: 212-6 March 2005
    A. Mortell; L. Fourcade; V. Solari; P. Puri

    [Preview] [Read]

  • 21.   Bioadhesive patch-based delivery of 5-aminolevulinic acid to the nail for photodynamic therapy of onychomycosis

    The aim of this study was to examine if sufficient concentrations of 5-aminolevulinic acid could be achieved within the nail matrix, and at the nail bed, whether ALA-based photodynamic therapy may prove to be a useful treatment for onychomycosis.

    J Control Release, Vol: 103 Page: 381-92 March 2005
    R. F. Donnelly; P. A. McCarron; J. M. Lightowler; A. D. Woolfson

    [Preview] [Read]

  • 22.   Campylobacter jejuni adhere to and invade chicken intestinal epithelial cells in vitro

    The aim of this study was to compare the interaction of Campylobacter jejuni with primary intestinal cells from humans and poultry to identify factors that account for the divergent outcome following Campylobacter exposure

    Microbiology, Vol: 153 Page: 561-9 February 2007
    C. M. Byrne; M. Clyne; B. Bourke

    [Preview] [Read]

  • 23.   Candidate genes and the behavioral phenotype in 22q11.2 deletion syndrome

    This article discusses candidate genes and the behavioural phenotype in 22q11.2 deletion syndrome and the association with schizophrenia

    Dev Disabil Res Rev, Vol: 14 Page: 26-34 2008
    S. E. Prasad; S. Howley; K. C. Murphy

    [Preview] [Read]

  • 24.   Cardiac gene expression and synthesis of atrial natriuretic peptide in the nitrofen model of congenital diaphragmatic hernia in rats: effect of prenatal dexamethazone treatment

    The aim of this study was to determine the gene and protein levels of atrial natriuretic peptide in the heart of nitrofen-induced congenital diaphragmatic hernia in rats and to evaluate the effect of antenatal dexamethazone treatment

    J Pediatr Surg, Vol: 36 Page: 1497-501 October 2001
    N. Guarino; H. Shima; P. Puri

    [Preview] [Read]

  • 25.   Cell death in the early adriamycin rat model

    The aim of this study was to investigate the hypothesise of increased cell death in adriamycin-exposed embryos

    Pediatr Surg Int, Vol: 18 Page: 576-80 October 2002
    J. Gillick; S. Giles; J. Bannigan; P. Puri

    [Preview] [Read]

  • 26.   Comparison of phenotypic and genotypic characteristics of Salmonella bredeney associated with a poultry-related outbreak of gastroenteritis in Northern Ireland

    The aim of this study was to investigate a combination of phenotypic and genotypic subspecies typing methods to aid in an epidemiological investigation of an outbreak of Salmonella bredeney

    J Infect, Vol: 47 Page: 33-9 July 2003
    J. E. Moore; L. Murray; S. Fanning; M. Cormican; M. Daly; N. Delappe; B. Morgan; P. G. Murphy

    [Preview] [Read]

  • 27.   Corticosteroids in the prevention and management of bronchopulmonary dysplasia

    This article discusses evidence-based guidelines for postnatal steroid therapy in the management of chronic lung disease.

    Semin Neonatol, Vol: 8 Page: 83-91 February 2003
    D. G. Grier; H. L. Halliday

    [Preview] [Read]

  • 28.   Dead cattle, lead and child health

    This aim of this study was to screen for lead toxicity in a local school population

    Ir Med J, Vol: 96 Page: 232-4 September 2003
    E. Feely; C. Garavan; K. Kelleher

    [Preview] [Read]

  • 29.   Decreased expression of voltage-gated K+ channels in pulmonary artery smooth muscles cells in nitrofen-induced congenital diaphragmatic hernia in rats

    The aim of this study was to test the hypothesize that the hyperreactivity of the newborn pulmonary vasculature in congenital diaphragmatic hernia might reflect a relatively low level of smooth muscle K(+) channel activity because of hypoxemia

    Pediatr Surg Int, Vol: 20 Page: 192-6 March 2004
    M. Sakai; K. Unemoto; V. Solari; P. Puri

    [Preview] [Read]

  • 30.   Demonstration of intrinsic innervation of the guinea pig upper urinary tract using whole-mount preparation

    The aim of this study was to describe the morphology and functional importance of the autonomic nervous system in the upper urinary tract

    Neurourol Urodyn, Vol: 27 Page: 341-7 2008
    U. Rolle; E. Brylla; B. Tillig; B. Chertin; S. Cascio; P. Puri

    [Preview] [Read]

  • 31.   Demonstration of nitrergic and cholinergic innervation in whole-mount preparations of rabbit, pig, and human upper urinary tract

    The aim of this study was to investigate the distribution of nitrergic and cholinergic innervation in rabbit, pig, and human upper urinary tract

    Pediatr Surg Int, Vol: 18 Page: 315-8 September 2002
    U. Rolle; B. Chertin; L. Nemeth; P. Puri

    [Preview] [Read]

  • 32.   Detection of measles virus in children with ileo-colonic lymphoid nodular hyperplasia, enterocolitis and developmental disorder

    The aim of this study was detect measles virus in children with ileo-colonic lymphoid nodular hyperplasia, enterocolitis and developmental disorder

    Mol Psychiatry, Vol: 7 Suppl 2 Page: S47-8 2002
    C. M. Martin; V. Uhlmann; A. Killalea; O. Sheils; J. J. O'Leary

    [Preview] [Read]

  • 33.   Detection of multiple allergen-specific IgEs on microarrays by immunoassay with rolling circle amplification

    This study aimed to describe the detection of multiple allergen-specific IgEs on microarrays by immunoassay with rolling circle amplification

    Clin Chem, Vol: 46 Page: 1990-3 December 2000
    S. Wiltshire; S. O'Malley; J. Lambert; K. Kukanskis; D. Edgar; S. F. Kingsmore; B. Schweitzer

    [Preview] [Read]

  • 34.   Developmental changes in submucosal nitrergic neurons in the porcine distal colon

    The aim of this study was to determine the normal nitrergic neuronal density and morphology in the submucosal plexus of the porcine distal bowel from fetal life to adulthood

    J Pediatr Surg, Vol: 41 Page: 1029-35 May 2006
    S. Montedonico; T. Sri Paran; M. Pirker; U. Rolle; P. Puri

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  • 35.   Developmental changes of the adrenergic network in the myenteric plexus of the porcine small bowel

    The aim of this study was to investigate the age-related changes in the sympathetic innervation of the myenteric plexus

    Pediatr Surg Int, Vol: 23 Page: 659-63 July 2007
    T. Sri Paran; U. Rolle; P. Puri

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  • 36.   Differences in nitrergic innervation of the developing chick cloaca and colorectum

    The aim of this study was to investigate differences in nitrergic innervation of the developing chick cloaca and colorectum

    Pediatr Surg Int, Vol: 22 Page: 90-4 January 2006
    A. M. O'Donnell; J. Bannigan; P. Puri

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  • 37.   Dissociation in performance of children with ADHD and high-functioning autism on a task of sustained attention

    The aim of this study was to examine the executive function of two neurodevelopmental disorders attention deficit hyperactivity disorder and autism using a sustained attention task with a validated brain-behaviour basis

    Neuropsychologia, Vol: 45 Page: 2234-45 June 2007
    K. A. Johnson; I. H. Robertson; S. P. Kelly; T. J. Silk; E. Barry; A. Daibhis; A. Watchorn; M. Keavey; M. Fitzgerald; L. Gallagher; M. Gill; M. A. Bellgrove

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  • 38.   Distribution of megaplasmids in Lactobacillus salivarius and other lactobacilli

    The aim of this study was to examine the study characterised aspect of lactobacillus salivarius

    J Bacteriol, Vol: 189 Page: 6128-39 September 2007
    Y. Li; C. Canchaya; F. Fang; E. Raftis; K. A. Ryan; J. P. van Pijkeren; D. van Sinderen; P. W. O'Toole

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  • 39.   Downregulation of GATA4 and GATA6 in the heart of rats with nitrofen-induced diaphragmatic hernia

    The aim of this study was to test the hypothesize that expression of GATA4 and GATA6 is reduced in early stages of gestation in a congenital diaphragmatic hernia hypoplastic heart

    J Pediatr Surg, Vol: 43 Page: 362-6 February 2008
    H. Takayasu; H. Sato; K. Sugimoto; P. Puri

    [Preview] [Read]

  • 40.   Down-regulation of Wnt signal pathway in nitrofen-induced hypoplastic lung

    The aim of this study was to test the hypothesize that Wnt-mediated signaling is altered in nitrofen-induced hypoplastic lungs

    J Pediatr Surg, Vol: 42 Page: 426-30 February 2007
    H. Takayasu; N. Nakazawa; S. Montedonico; P. Puri

    [Preview] [Read]

  • 41.   Effect of hyperoxia on surfactant protein gene expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats

    The aim of this study was to investigate SP mRNA expression in hypoplastic congenital diaphragmatic hernia lung in rats during mechanical ventilation in order to determine the effect of O2 on SP synthesis in congenital diaphragmatic hernia

    Pediatr Surg Int, Vol: 16 Page: 473-7 2000
    H. Shima; N. Guarino; P. Puri

    [Preview] [Read]

  • 42.   Effect of mechanical ventilation on the pulmonary expression and production of elastin in nitrofen-induced diaphragmatic hernia in rats

    The aim of this study was to investigate the expression and production of elastin in the lung in newborn rats with congenital diaphragmatic hernia during mechanical ventilation

    J Pediatr Surg, Vol: 37 Page: 1253-7 September 2002
    N. Guarino; H. Teramoto; H. Shima; T. Oue; P. Puri

    [Preview] [Read]

  • 43.   Effect of nitric oxide on fibroblast growth factor-10 and bone morphogenetic protein 4 expressions in the branching morphogenesis of fetal rat lung explants

    The aim of this study was to investigate the effect of nitric oxide on fibroblast growth factor-10 and bone morphogenetic protein 4 expressions in the branching morphogenesis of fetal rat lung explants

    J Pediatr Surg, Vol: 40 Page: 1030-3 June 2005
    M. Shinkai; T. Shinkai; M. A. Pirker; S. Montedonico; P. Puri

    [Preview] [Read]

  • 44.   Effect of nitric oxide on the development of nitrofen-induced fetal hypoplastic lung explants

    The aim of this study was to evaluate the effect of nitric oxide on the morphogenesis of hypoplastic lung using nitrofen-induced rat lung explant model

    J Pediatr Surg, Vol: 40 Page: 17-21 January 2005
    M. Shinkai; T. Shinkai; M. E. Pirker; S. Montedonico; P. Puri

    [Preview] [Read]

  • 45.   Effect of VEGF on the branching morphogenesis of normal and nitrofen-induced hypoplastic fetal rat lung explants

    The aim of this study was to test the hypothesize that vascular endothelial growth factor may accelerate branching morphogenesis and thus may modulate lung growth in normal and nitrofen-induced pulmonary hypoplastic lungs

    J Pediatr Surg, Vol: 41 Page: 781-6 April 2006
    M. Shinkai; T. Shinkai; S. Montedonico; P. Puri

    [Preview] [Read]

  • 46.   Enteric nervous system and developmental abnormalities in childhood

    This article reports on the enteric nervous system and developmental abnormalities in childhood

    Pediatr Surg Int, Vol: 22 Page: 945-59 December 2006
    T. S. Paran; U. Rolle; P. Puri

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  • 47.   Evaluation of a water-soluble bioadhesive patch for photodynamic therapy of vulval lesions

    The aim of this study was to examine a innovative bioadhesive patch intended primarily as a vulval drug delivery system

    Int J Pharm, Vol: 293 Page: 11-23 April 2005
    P. A. McCarron; R. F. Donnelly; A. Zawislak; A. D. Woolfson; J. H. Price; R. McClelland

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  • 48.   Expression of a novel P275L variant of NADH:cytochrome b5 reductase gives functional insight into the conserved motif important for pyridine nucleotide binding

    The aim of this study was to investigate the clinical disorder of recessive congenital methemoglobinemia

    Arch Biochem Biophys, Vol: 447 Page: 59-67 March 2006
    M. J. Percy; L. J. Crowley; J. Boudreaux; M. J. Barber

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  • 49.   Expression of vasoactive mediators during mechanical ventilation in nitrofen-induced diaphragmatic hernia in rats

    The aim of this study was to investigate mRNA expression of ET-1, eNOS, and CGRP in congenital diaphragmatic hernia lung in the perinatal period

    Pediatr Surg Int, Vol: 21 Page: 143-7 March 2005
    T. Shinkai; H. Shima; V. Solari; P. Puri

    [Preview] [Read]

  • 50.   Food allergies

    This article discusses aspects of true food allergies, implying immune-mediated adverse responses to food antigens, discussing the importance of IgE-mediated and non-IgE-mediated immune mechanisms

    Curr Gastroenterol Rep, Vol: 4 Page: 373-82 October 2002
    P. F. O'Leary; F. Shanahan

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  • 51.   Gene expression of fibroblast growth factors 10 and 7 is downregulated in the lung of nitrofen-induced diaphragmatic hernia in rats

    The aim of this study was to determine the gene level expression of fibroblast growth factors-10 and FGF-7 in the lung of nitrofen-induced congenital diaphragmatic hernia

    J Pediatr Surg, Vol: 38 Page: 1021-4 July 2003
    H. Teramoto; A. Yoneda; P. Puri

    [Preview] [Read]

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