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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Neuroblastoma/ genetics/pathology

Your search returns 2 documents

• 1.   Are gains of chromosomal regions 7q and 11p important abnormalities in neuroblastoma?

  The aim of this study was to examine if gains of chromosomal regions 7q and 11p are important abnormalities in neuroblastoma

  

  Abstract:

  Neuroblastoma exhibiting deletion of a segment of the long arm of chromosome 11 represents a genetic subtype of tumor that is distinct from those exhibiting MYCN amplification or 1p deletion. The 11q- genetic subtype is further characterized by gain of 17q and loss of distal 3p material. Gain of 11p material has also been reported in neuroblastoma with 11q loss, but at a considerably more...

  International Classification:

  Neoplasms - Malignant neoplasms - neuroblastoma

  Categories:

  neuroblastoma

  Geography:

  Republic of Ireland

  Cancer Genet Cytogenet, Vol: 140 Page: 133-7 January 2003
  R. L. Stallings; J. Howard; A. Dunlop; M. Mullarkey; M. McDermott; F. Breatnach; A. O'Meara

  [Preview] [Read]

• 2.   Evolution of unbalanced gain of distal chromosome 2p in neuroblastoma

  The aim of this study was to examine the evolution of unbalanced gain of distal chromosome 2p in neuroblastoma

  

  Abstract:

  Neuroblastoma, one of the most common tumors of childhood, presents at diagnosis with a vast number of recurrent chromosomal imbalances that include hyperdiploidy for whole chromosomes, partial loss of 1p, 3p, 4p, 11q, 14q, partial gain of 1q, 7q, 17q and amplification of MYCN. These abnormalities are nonrandomly distributed in neuroblastoma as loss of 3p and 11q rarely occur in MYCN more...

  International Classification:

  Neoplasms - Malignant neoplasms - neuroblastoma

  Categories:

  neuroblastoma

  Geography:

  International

  Cytogenet Genome Res, Vol: 106 Page: 49-54 2004
  R. L. Stallings; P. Carty; L. McArdle; M. Mullarkey; M. McDermott; A. O'Meara; E. Ryan; D. Catchpoole; F. Breatnach

  [Preview] [Read]