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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Neuroblastoma/ genetics

Your search returns 2 documents

• 1.   Coordinate deletion of chromosome 3p and 11q in neuroblastoma detected by comparative genomic hybridization

  The aim of this study was to provide insight into some of the less commonly observed abnormalities in neuroblastoma, by performing comparative genomic hybridization analysis on 24 primary and metastatic neuroblastomas

  

  Abstract:

  Neuroblastoma, the most common extracranial solid tumor of childhood, is associated with a number of genetic abnormalities that are prognostically significant. The most common abnormalities are associated with aggressive clinical behavior and include deletion of distal chromosome 1p, NMYC amplification, and unbalanced gain of the long arm of chromosome 17. There are also other more...

  International Classification:

  Neoplasms - Malignant neoplasms - neuroblastoma

  Categories:

  neuroblastoma

  Geography:

  Republic of Ireland

  Cancer Genet Cytogenet, Vol: 120 Page: 44-9 July 2000
  C. J. Breen; A. O'Meara; M. McDermott; M. Mullarkey; R. L. Stallings

  [Preview] [Read]

• 2.   Molecular cytogenetic analysis of recurrent unbalanced t(11;17) in neuroblastoma

  This study aimed to examine molecular cytogenetic analysis of recurrent unbalanced t(11;17) in neuroblastoma

  

  Abstract:

  Loss of 11q material occurs in approximately 30% of advanced stage neuroblastoma and defines a distinct genetic subtype of this disease. These tumors almost always possess unbalanced gain of the 17q, along with many additional recurrent chromosomal imbalances. Loss of 11q and gain of 17q is often the consequence of an unbalanced translocation between the long arms of both chromosomes, more...

  International Classification:

  Effectiveness of measurement tool - molecular cytogenetic analysis

  Geography:

  Republic of Ireland

  Cancer Genet Cytogenet, Vol: 154 Page: 44-51 October 2004
  R. L. Stallings; P. Carty; L. McArdle; M. Mullarkey; M. McDermott; F. Breatnach; A. O'Meara

  [Preview] [Read]