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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Proto-Oncogene Proteins c-kit/metabolism

Your search returns 3 documents

• 1.   Distribution of Ca2+-activated K channels, SK2 and SK3, in the normal and Hirschsprung's disease bowel

  The aim of this study was to investigate the expression and distribution of SK2 and SK3 channels in the normal and Hirschsprung's disease bowel

  

  Abstract:

  PURPOSE: The aim of this study was to investigate the expression and distribution of SK2 and SK3 channels in the normal and Hirschsprung's disease (HD) bowel. METHODS: Full-thickness colonic specimens were collected at pull-through operation from 10 patients with HD and from 6 patients during bladder augmentation. Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis for SK2 more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease

  Categories:

  expression and distribution of SK2 and SK3; -Hirschsprung's disease

  Geography:

  Republic of Ireland

  J Pediatr Surg, Vol: 38 Page: 978-83 June 2003
  A. P. Piotrowska; V. Solari; P. Puri

  [Preview] [Read]

• 2.   Immunocolocalization of the heme oxygenase-2 and interstitial cells of Cajal in normal and aganglionic colon

  The aim of this study was to investigate the immunocolocalization of the HO-2 and interstitial cells of Cajal in normal and aganglionic bowel of Hirschsprung's disease

  

  Abstract:

  PURPOSE: Interstitial cells of Cajal (ICCs) are pacemaker cells that play an important role in the control of gut motility. Carbon monoxide (CO) has been proposed as an endogenous messenger molecule between ICC and smooth muscle cells in the gastrointestinal tract (GIT). Heme oxygenase-2 (HO-2) is the main physiologic mechanism for generating CO in human cells. The aim of this study was more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease

  Categories:

  immunocolocalization of the HO-2 and interstitial cells of Cajal;-Hirschsprung's disease

  Geography:

  Republic of Ireland

  J Pediatr Surg, Vol: 38 Page: 73-7 January 2003
  A. P. Piotrowska; V. Solari; D. de Caluwe; P. Puri

  [Preview] [Read]

• 3.   Increased expression of mast cells in reflux nephropathy

  The aim of this study was to examine the distribution of mast cells in kidneys with reflux nephropathy and to determine the relationship between mast cells and the interstitial fibrotic process in reflux nephropathy

  

  Abstract:

  End-stage renal disease is characterized by interstitial infiltrate of inflammatory cells in association with tubular atrophy and interstitial fibrosis. Mast cells (MCs) secrete a large number of fibrogenic factors and have been implicated in chronic inflammatory processes with fibrous tissue deposition. The aim of this study was to investigate the distribution of MCs in kidneys with more...

  International Classification:

  Diseases of the genitourinary system - reflux nephropathy

  Categories:

  kidney mast cells; - reflux nephropathy

  Geography:

  Republic of Ireland

  Pediatr Nephrol, Vol: 19 Page: 157-63 February 2004
  V. Solari; K. Unemoto; A. Piaseczna Piotrowska; P. Puri

  [Preview] [Read]