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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Cell Line, Tumor

Your search returns 3 documents

• 1.   Host cell tropism underlies species restriction of human and bovine Cryptosporidium parvum genotypes

  The aim of the study was to examine the urban-rural variation in mortality and hospital admission rates for unintentional injury in Ireland

  

  Abstract:

  It has been recognized recently that human cryptosporidiosis is usually caused by Cryptosporidium parvum genotype I ("human" C. parvum), which is not found in animals. Compared to C. parvum genotype II, little is known of the biology of invasion of the human-restricted C. parvum genotype I. The aims of the present study were (i) to explore and compare with genotype II the more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - unintentional injury

  Categories:

  urban-rural variation in mortality

  Geography:

  Republic of Ireland

  Infect Immun, Vol: 72 Page: 6125-31 October 2004
  A. Hashim; M. Clyne; G. Mulcahy; D. Akiyoshi; R. Chalmers; B. Bourke

  [Preview] [Read]

• 2.   Interaction of Cryptosporidium hominis and Cryptosporidium parvum with primary human and bovine intestinal cells

  The aim of this study was to compare the mechanisms of Cryptosporidium parvum and Cryptosporidium hominis invasion using a primary cell model of infection

  

  Abstract:

  Cryptosporidiosis in humans is caused by the zoonotic pathogen Cryptosporidium parvum and the anthroponotic pathogen Cryptosporidium hominis. To what extent the recently recognized C. hominis species differs from C. parvum is unknown. In this study we compared the mechanisms of C. parvum and C. hominis invasion using a primary cell model of infection. Cultured primary bovine and human more...

  Categories:

  Cryptosporidium parvum; Cryptosporidium hominis; mechanisms of infection

  Geography:

  Republic of Ireland

  Infect Immun, Vol: 74 Page: 99-107 January 2006
  A. Hashim; G. Mulcahy; B. Bourke; M. Clyne

  [Preview] [Read]

• 3.   Invasion of human epithelial cells by Campylobacter upsaliensis

  This characterized the ability of Campylobacter upsaliensis to invade both cultured epithelial cell lines and primary human small intestinal cells

  

  Abstract:

  Few data exist on the interaction of Campylobacter upsaliensis with host cells, and the potential for this emerging enteropathogen to invade epithelial cells has not been explored. We have characterized the ability of C. upsaliensis to invade both cultured epithelial cell lines and primary human small intestinal cells. Epithelial cell lines of intestinal origin appeared to be more more...

  Geography:

  Republic of Ireland

  Cell Microbiol, Vol: 5 Page: 835-47 November 2003
  A. Mooney; C. Byrne; M. Clyne; K. Johnson-Henry; P. Sherman; B. Bourke

  [Preview] [Read]