Irish Child Health Database - Peer Reviewed Papers
Nervous System Diseases/ chemically induced
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Corticosteroids were first prescribed for preterm neonates to treat respiratory distress syndrome, but they were found to have no beneficial effect in this disorder. About 20 years ago, dexamethasone was first used to treat infants with bronchopulmonary dysplasia who were ventilator dependent after the age of 3 weeks. There were short-term benefits, with an improvement in lung function more...
Semin Neonatol, Vol: 8 Page: 83-91 February 2003
D. G. Grier; H. L. Halliday
Postnatal corticosteroids given early after birth reduce the risk of chronic lung disease in preterm infants but are associated with an approximate doubling of the risk of adverse neurosensory outcomes. Corticosteroids given after 7-10 d of age appear not to have these increased risks of neurosensory sequelae and reduce time on the ventilator. CONCLUSION: Further research is needed to more...
Acta Paediatr, Vol: 92 Page: 888-9 August 2003
H. L. Halliday