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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Nuclear Proteins

Your search returns 2 documents

• 1.   Equivalent functional nuclear factor of activated T cell 1 mRNA and protein expression in cord blood and adult T cells

  The aim of this study was to examine nuclear factor of activated T cell 1 expression in cord blood cells

  

  Abstract:

  Cord blood (CB) cells are now an important source of stem cells for bone marrow reconstitution as a result of the decreased risk of graft-versus-host disease that was attributed to previously reported absent or diminished nuclear factor of activated T (NFAT) cell 1 expression by CB T cells. This study reexamines NFAT1 expression in CB T cells. CB T cells were examined for NFAT1 mRNA and more...

  International Classification:

  Other - Transcription factors -nuclear factor of activated T cell 1 expression

  Categories:

  nuclear factor of activated T cell 1 expression; cord blood cells

  Geography:

  Republic of Ireland

  Transplantation, Vol: 76 Page: 1526-8 November 2003
  R. M. O'Neill; D. J. Reen

  [Preview] [Read]

• 2.   Human recent thymic emigrants--identification, expansion, and survival characteristics

  The aim of this study was to examine in humans at birth, circulating T cells represent recent thymic emigrants as reflected in their high level of expression of TCR excision circles

  

  Abstract:

  This study shows that, in humans at birth, circulating T cells represent recent thymic emigrants (RTEs) as reflected in their high level of expression of TCR excision circles. RTEs express "thymocyte-like" characteristics with regard to rapid rate of apoptosis. In the presence of common gamma-chain cytokines, in particular IL-7, they show enhanced potential to survive, entry more...

  International Classification:

  Immunology - thymic emigrants

  Categories:

  recent thymic emigrants;

  Geography:

  Republic of Ireland

  J Immunol, Vol: 167 Page: 1970-6 August 2001
  J. Hassan; D. J. Reen

  [Preview] [Read]