Accessibility
Legal Notices
Text Version

Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Nitric Oxide Synthase Type I

Your search returns 3 documents

• 1.   Nitrergic hyperinnervation in appendicitis and in appendices histologically classified as normal

  The aim of this study was to examine the nitrergic innervation of (a) inflamed appendices (b) appendices classified as histologically normal from patients with a clinical diagnosis of appendicitis (c) normal control appendix specimens

  

  Abstract:

  CONTEXT: The pathogenesis of appendicitis remains poorly understood. Despite new diagnostic techniques, appendices removed from patients with suspected appendicitis often appear histologically normal on conventional examination. There is increasing evidence of involvement of the enteric nervous system in immune regulation and in inflammatory responses in the gastrointestinal system. more...

  International Classification:

  Diseases of the digestive system - Diseases of appendix - appendixes

  Categories:

  nitrergic innervation; appendix

  Geography:

  Republic of Ireland

  Arch Pathol Lab Med, Vol: 127 Page: 573-8 May 2003
  L. Nemeth; U. Rolle; D. J. Reen; P. Puri

  [Preview] [Read]

• 2.   The role of nitric oxide in reflux nephropathy

  The aim of this study was to investigate the expression of different isoforms of nitric oxide synthase in severe refluxing kidneys to understand the pathogenesis of reflux nephropathy in kidney specimens in children with severe reflux nephropathy

  

  Abstract:

  Reflux nephropathy (RN) is recognized as a major cause of end-stage renal failure in children and young adults. Inhibition of nitric oxide (NO) exacerbates and enhanced production ameliorates tubulointerstitial fibrosis (TIF) in experimental obstructive uropathy. NO is synthesised by NO synthase (NOS), three distinct isoforms of which have been identified: inducible (iNOS), endothelial more...

  International Classification:

  Diseases of the genitourinary system - reflux nephropathy

  Categories:

  nitric oxide synthase; refluxing kidneys/reflux nephropathy

  Geography:

  Republic of Ireland

  Pediatr Surg Int, Vol: 18 Page: 630-4 October 2002
  B. Chertin; U. Rolle; A. Farkas; P. Puri

  [Preview] [Read]

• 3.   Three-dimensional morphology of c-Kit-positive cellular network and nitrergic innervation in the human gut

  The aim of this study was to examine the distribution of nitrergic innervation and interstitial cells of Cajal in normal human bowel

  

  Abstract:

  CONTEXT:-c-Kit-positive interstitial cells of Cajal (ICC) appear to play a key role in the normal motility function and development of intestine. Nitric oxide is considered to be the most important messenger of inhibitory nonadrenergic, noncholinergic nerves in the enteric nervous system. OBJECTIVES: The aims of this study were to examine the distribution of nitrergic innervation and more...

  International Classification:

  Other - the human gut

  Categories:

  the human gut

  Geography:

  Republic of Ireland

  Arch Pathol Lab Med, Vol: 125 Page: 899-904 July 2001
  L. Nemeth; P. Puri

  [Preview] [Read]