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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Desmin/metabolism

Your search returns 2 documents

• 1.   Altered cytoskeleton in smooth muscle of aganglionic bowel

  The aim of this study was to examine the distribution of the cytoskeletal proteins in the smooth muscle of the aganglionic bowel

  

  Abstract:

  CONTEXT: Intestinal motility is under the control of smooth muscle cells, enteric plexus, and hormonal factors. In Hirschsprung disease (HD), the aganglionic colon remains spastic or tonically enhanced and unable to relax. The smooth muscle cell's cytoskeleton consists of proteins or structures whose primary function is to link or connect protein filaments to each other or to the more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease

  Categories:

  cytoskeletal proteins; aganglionic bowel(Hirschsprung disease)

  Geography:

  Republic of Ireland

  Arch Pathol Lab Med, Vol: 126 Page: 692-6 June 2002
  L. Nemeth; U. Rolle; P. Puri

  [Preview] [Read]

• 2.   Structural immaturity of the pylorus muscle in infantile hypertrophic pyloric stenosis

  The aim of this study was to analyze the expression of desmin in infantile hypertrophic pyloric stenosis

  

  Abstract:

  Recent reports indicate that extracellular matrix and cytoskeleton plasmalemmal elements are altered in infantile hypertrophic pyloric stenosis (IHPS). Desmin is a cytoskeletal protein that is important for the organization and function of muscular fibers. It has been found to be increased in the smooth muscle in chronic intestinal pseudo-obstruction and in skeletal muscle in some forms more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - congenital hypertrophic pyloric stenosis

  Categories:

  desmin; -hypertrophic pyloric stenosis

  Geography:

  Republic of Ireland

  Pediatr Surg Int, Vol: 16 Page: 282-4 2000
  N. Guarino; H. Shima; P. Puri

  [Preview] [Read]