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Abnormalities, Drug-Induced/epidemiology/ pathology
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The aim of this study was to test the hypothesis that Adriamycin administration during a particular time frame could yield a high incidence of urinary tract anomalies
Abstract:
Congenital obstructive uropathy is associated with significant morbidity and mortality in the human neonate. The pathophysiology of congenital obstructive uropathy is poorly understood. There are very few experimental models of prenatal obstruction of the urinary tract, except in the fetal lamb or inbred rats. Prenatal exposure to Adriamycin in a rat model leads to a spectrum of more...
Categories:
adriamycin administration; urinary tract anomalies
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 21 Page: 212-6 March 2005
A. Mortell; L. Fourcade; V. Solari; P. Puri
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