Irish Child Health Database - Peer Reviewed Papers
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The aim of this study was to investigate the expression of insulin like growth factor-1 in reflux nephropathy
Abstract:
BACKGROUND: Reflux nephropathy (RN) is recognised as a major cause of end-stage renal failure in children and young adults. Insulin-like growth factor-1 (IGF-1), a peptide growth factor produced by collecting ducts, and its receptor, insulin-like growth factor-1 receptor (IGF-1R), are present in the glomeruli and basolateral membrane of renal proximal tubular cells. Exogenous IGF-1 has more...
International Classification:
Diseases of the genitourinary system - reflux nephropathy
Categories:
insulin like growth factor-1; - reflux nephropathy
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 20 Page: 283-9 April 2004
B. Chertin; A. Farkas; P. Puri
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