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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Great Britain/epidemiology

Your search returns 71 documents

Page:
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• 1.   A longitudinal study of iron status in children at 12, 24 and 36 months

  The aim of this study was to assess iron status in a sample of clinically well, Caucasian children and explore the complex factors which contribute to iron deficiency during infancy

  

  Abstract:

  OBJECTIVES: To assess iron status in a sample of clinically well, Caucasian children and explore the complex factors which contribute to iron deficiency during infancy. DESIGN: Infants recruited at birth and followed longitudinally at 1, 2, 3, 4, 5, 6, 9, 12, 24 and 36 months; feeding practices and socioeconomic data recorded. Iron status assessed using venous blood at 12, 24 and 36 more...

  International Classification:

  Other - iron status

  Categories:

  iron status

  Geography:

  Republic of Ireland

  Public Health Nutr, Vol: 1 Page: 93-100 June 1998
  V. E. Freeman; J. Mulder; M. A. van't Hof; H. M. Hoey; M. J. Gibney

  [Preview] [Read]

• 2.   Active surveillance of hepatitis C infection in the UK and Ireland

  The aim of this study was to examine the prevalence, distribution, and clinical details of paediatric hepatitis C virus infection in the United Kingdom and Ireland.

  

  Abstract:

  AIM: To investigate the prevalence, distribution, and clinical details of paediatric hepatitis C virus (HCV) infection in the UK and Ireland. METHODS: Active monthly surveillance questionnaire study coordinated through the British Paediatric Surveillance Unit, to all consultant paediatricians in 1997 and 1998. RESULTS: A total of 182 HCV infected children were reported from 54 centres more...

  International Classification:

  Certain infectious and parasitic diseases - Viral hepatitis - hepatitis C

  Categories:

  paediatric hepatitis C virus

  Geography:

  Republic of Ireland and the United Kingdom

  Arch Dis Child, Vol: 82 Page: 286-91 April 2000
  D. M. Gibb; P. E. Neave; P. A. Tookey; M. Ramsay; H. Harris; K. Balogun; D. Goldberg; G. Mieli-Vergani; D. Kelly

  [Preview] [Read]

• 3.   All patients receiving renal replacement therapy in the United Kingdom in 2005 (chapter 4)

  The aim of this study was to examine renal replacement therapy in the United Kingdom with regard to prevalence and a range of demographic characteristics

  

  Abstract:

  Summary data are provided for the whole United Kingdom. There were 41,776 adult patients alive on renal replacement therapy (RRT) in the UK at the end of 2005, a prevalence for adults of 694 pmp. Addition of 748 children under the age of 18 on RRT gives a total prevalence of 706 pmp. The more detailed analysis includes data on 37,534 patients from 65 of the 70 units which returned more...

  International Classification:

  Health service provision

  Categories:

  renal replacement therapy

  Geography:

  the United Kingdom

  Nephrol Dial Transplant, Vol: 22 Suppl 7 Page: vii30-50 August 2007
  K. Farrington; R. Rao; R. Stenkamp; D. Ansell; T. Feest

  [Preview] [Read]

• 4.   Antimicrobial policies in the neonatal units of the United Kingdom and Republic of Ireland

  This study aimed to explore antibiotic and antifungal policies in British and Irish neonatal units

  

  Abstract:

  OBJECTIVES: To review antibiotic and antifungal policies in British and Irish neonatal units (NNUs). METHODS: A telephone survey was performed regarding empirical antimicrobial guidelines of NNUs in the UK and Republic of Ireland. RESULTS: The response rate was 91% (202 of 222 NNUs). The guidelines from all responding units covered group B Streptococcus and Escherichia coli, the most more...

  International Classification:

  Practice/knowledge - antibiotic and antifungal policies in neonatal units

  Categories:

  antibiotic and antifungal policies in neonatal units

  Geography:

  Republic of Ireland and the United Kingdom

  J Antimicrob Chemother, Vol: 61 Page: 743-5 March 2008
  A. M. Fernando; P. T. Heath; E. N. Menson

  [Preview] [Read]

• 5.   Antimicrobial susceptibility of lower respiratory tract pathogens in Great Britain and Ireland 1999-2001 related to demographic and geographical factors: the BSAC Respiratory Resistance Surveillance Programme

  The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors

  

  Abstract:

  OBJECTIVE: The aim of this study was to assess the antimicrobial susceptibility of community-acquired lower respiratory pathogens in Great Britain and Ireland, and investigate its relationship with demographic and geographical factors using multiple logistic regression analysis. METHODS: A total of 1328 isolates of Streptococcus pneumoniae, 1894 Haemophilus influenzae and 845 Moraxella more...

  International Classification:

  Diseases of the respiratory system - lower respiratory pathogens

  Categories:

  lower respiratory pathogens

  Geography:

  Republic of Ireland and the United Kingdom

  J Antimicrob Chemother, Vol: 52 Page: 931-43 December 2003
  R. Reynolds; J. Shackcloth; D. Felmingham; A. MacGowan

  [Preview] [Read]

• 6.   Antiretroviral therapy and premature delivery in diagnosed HIV-infected women in the United Kingdom and Ireland

  The aim of this study was to examine the association between antiretroviral therapy in pregnancy and premature delivery, birthweight, stillbirth and neonatal mortality, in pregnancies in HIV-infected women delivering between 1990 and 2005

  

  Abstract:

  OBJECTIVE: To explore the association between antiretroviral therapy in pregnancy and premature delivery, birthweight, stillbirth and neonatal mortality, in pregnancies in HIV-infected women delivering between 1990 and 2005. DESIGN: Pregnancies in women with diagnosed HIV infection in the UK and Ireland are notified to the National Study of HIV in Pregnancy and Childhood (NSHPC) through more...

  International Classification:

  Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV

  Categories:

  antiretroviral therapy in pregnancy

  Geography:

  Republic of Ireland and the United Kingdom

  Aids, Vol: 21 Page: 1019-26 May 2007
  C. L. Townsend; M. Cortina-Borja; C. S. Peckham; P. A. Tookey

  [Preview] [Read]

• 7.   Association between PRODH and schizophrenia is not confirmed

  The aim of this study was to examine the association between proline oxidase and schizophrenia

  

  International Classification:

  Mental and behavioural disorders - Schizophrenia, schizotypal and delusional disorders - schizophrenia

  Categories:

  proline oxidase; -schizophrenia

  Geography:

  Republic of Ireland and the United Kingdom

  Mol Psychiatry, Vol: 8 Page: 644-5 July 2003
  H. J. Williams; N. Williams; G. Spurlock; N. Norton; D. Ivanov; R. G. McCreadie; A. Preece; V. Sharkey; S. Jones; S. Zammit; I. Nikolov; I. Kehaiov; A. Thapar; K. C. Murphy; G. Kirov; M. J. Owen; M. C. O'Donovan

  [Preview] [Read]

• 8.   Behavioural characteristics and autistic features in individuals with Cohen Syndrome

  The aim of this study was to describe behavioural characteristics and autistic features in individuals with Coen Syndrome

  

  Abstract:

  Diagnostic criteria for Cohen Syndrome are based largely on physical characteristics, and systematic information about behaviour and social functioning is limited. Typically, individuals with this condition are described as being very sociable and as showing low rates of pathology. However, recent studies have indicated that behavioural difficulties may occur more frequently than more...

  International Classification:

  Syndrome - Coen

  Categories:

  Coen Syndrome

  Geography:

  International

  Eur Child Adolesc Psychiatry, Vol: 14 Page: 57-64 March 2005
  P. Howlin; J. Karpf; J. Turk

  [Preview] [Read]

• 9.   Birth prevalence of cleft lip and palate in Northern Ireland (1981 to 2000)

  The aim of this study was to examine the prevalence of birth cleft lip and palate in Northern Ireland for the 20-year period 1981 to 2000, to determine the pattern of prevalence, and to report the proportion of different cleft types and sex distribution

  

  Abstract:

  OBJECTIVE: The prevalence of cleft lip and/or palate (CL/P) in Northern Ireland (NI) was last reported for 1980 through 1990. This study was undertaken to update the prevalence of CL/P in NI for the 20-year period 1981 to 2000, to determine the pattern of prevalence, and to report the proportion of different cleft types and sex distribution. DESIGN: Retrospective, population-based more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Cleft lip and cleft palate - Cleft lip and/or palate

  Categories:

  birth cleft lip; cleft palate

  Geography:

  Northern Ireland

  Cleft Palate Craniofac J, Vol: 45 Page: 141-7 March 2008
  T. A. Gregg; A. G. Leonard; C. Hayden; K. E. Howard; C. F. Coyle

  [Preview] [Read]

• 10.   Childhood hemolytic uremic syndrome, United Kingdom and Ireland

  The aim of this study was to examine disease incidence and clinical, epidemiologic and microbiologic characteristics childhood hemolytic uremic syndrome

  

  Abstract:

  We conducted prospective surveillance of childhood hemolytic uremic syndrome (HUS) from 1997 to 2001 to describe disease incidence and clinical, epidemiologic and microbiologic characteristics. We compared our findings, where possible, with those of a previous study conducted from 1985 to 1988. The average annual incidence of HUS for the United Kingdom and Ireland (0.71/100,000) was more...

  International Classification:

  Syndrome - hemolytic uremic

  Categories:

  hemolytic uremic syndrome

  Geography:

  Republic of Ireland and the United Kingdom

  Emerg Infect Dis, Vol: 11 Page: 590-6 April 2005
  R. M. Lynn; S. J. O'Brien; C. M. Taylor; G. K. Adak; H. Chart; T. Cheasty; J. E. Coia; I. A. Gillespie; M. E. Locking; W. J. Reilly; H. R. Smith; A. Waters; G. A. Willshaw

  [Preview] [Read]

• 11.   Childhood obesity--why should we be worried?

  This article discusses concerns over childhood obesity

  

  Geography:

  Republic of Ireland

  Ir Med J, Vol: 96 Page: 100-2 April 2003
  E. F. Roche

  [Preview] [Read]

• 12.   Chronic kidney disease post-liver transplantation

  This study determined the incidence of, and risk factors for, all stages of chronic kidney disease, as defined in the Kidney Disease Outcomes Quality Initiative Guideline

  

  Abstract:

  BACKGROUND: Renal disease is a recognized complication of orthotopic liver transplantation (OLT). We aimed to determine the incidence of all stages of chronic kidney disease (CKD), as defined in the Kidney Disease Outcomes Quality Initiative Guidelines. We also wanted to determine the risk factors for development of CKD and its impact on patient survival. METHODS: All patients who more...

  International Classification:

  Other - kidney disease

  Categories:

  chronic kidney disease

  Geography:

  Republic of Ireland

  Nephrol Dial Transplant, Vol: 21 Page: 2630-6 September 2006
  A. O'Riordan; V. Wong; P. A. McCormick; J. E. Hegarty; A. J. Watson

  [Preview] [Read]

• 13.   Clinical and immunological risk factors associated with Haemophilus influenzae type b conjugate vaccine failure in childhood

  The aim of this study was to examine the clinical and immunological risk factors associated with Haemophilus influenzae type b conjugate vaccine failure in childhood

  

  Abstract:

  Haemophilus influenzae type b (Hib) conjugate vaccines have proved extremely efficacious in healthy children. True Hib vaccine failures are rare. Hib conjugate vaccines were introduced for routine immunization in the United Kingdom and the Republic of Ireland in 1992. Coincident with this, active prospective and national surveillance via pediatricians, microbiologists, and public health more...

  International Classification:

  Bacterium - Haemophilus influenzae type b

  Categories:

  Haemophilus influenzae type b

  Geography:

  Republic of Ireland and the United Kingdom

  Clin Infect Dis, Vol: 31 Page: 973-80 October 2000
  P. T. Heath; R. Booy; H. Griffiths; E. Clutterbuck; H. J. Azzopardi; M. P. Slack; J. Fogarty; A. C. Moloney; E. R. Moxon

  [Preview] [Read]

• 14.   Clinical associations of autoantibodies to a p155/140 kDa doublet protein in juvenile dermatomyositis

  The aim of this study was to examine the clinical significance of anti-p155/140 autoantibodies in juvenile dermatomyositis

  

  Abstract:

  OBJECTIVES: Myositis-specific autoantibodies (MSAs) may define homogeneous clinical subsets of adult patients with dermatomyositis (DM). Recently, there have been descriptions of novel autoantibodies in DM. This study was conducted to establish the clinical significance of anti-p155/140 autoantibodies in juvenile DM (JDM). METHODS: The first 116 children recruited to the JDM National more...

  International Classification:

  Diseases of the musculoskeletal system and connective tissue - Systemic connective tissue disorders - dermatomyositis

  Categories:

  juvenile dermatomyositis

  Geography:

  Republic of Ireland

  Rheumatology (Oxford), Vol: 47 Page: 324-8 March 2008
  H. Gunawardena; L. R. Wedderburn; J. North; Z. Betteridge; J. Dunphy; H. Chinoy; J. E. Davidson; R. G. Cooper; N. J. McHugh

  [Preview] [Read]

• 15.   Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors

  The aim of this study was to examine the relationship between multiple genetic features, tumor morphology, and prognosis in neuroblastoma

  

  Abstract:

  PURPOSE: To determine the relationship between multiple genetic features, tumor morphology, and prognosis in neuroblastoma. PATIENTS AND METHODS: The genetic alterations and morphologic features that underpin three histopathologic risk classifications were analyzed in 108 neuroblastoma patients. Tumors were subdivided into four groups based on the three most frequent and prognostically more...

  International Classification:

  Neoplasms - Malignant neoplasms - neuroblastoma

  Categories:

  neuroblastoma

  Geography:

  Republic of Ireland and the United Kingdom

  J Clin Oncol, Vol: 19 Page: 3080-90 June 2001
  M. Lastowska; C. Cullinane; S. Variend; S. Cotterill; N. Bown; S. O'Neill; K. Mazzocco; P. Roberts; J. Nicholson; C. Ellershaw; A. D. Pearson; M. S. Jackson

  [Preview] [Read]

• 16.   Decline in mortality in children with HIV in the UK and Ireland: argument is flawed

  This article discusses the decline in mortality of children with HIV/AIDS

  

  Geography:

  Republic of Ireland and the United Kingdom

  Bmj, Vol: 328 Page: 523; author reply 524 February 2004
  S. W. Mhlongo; P. M. Maduna

  [Preview] [Read]

• 17.   Decline in mortality in children with HIV in the UK and Ireland: HIV positive adolescents urgently need dedicated services

  This article discusses the decline in Mortality of Children with HIV/AIDS - HIV positive adolescents urgently need dedicated services

  

  Geography:

  Republic of Ireland and the United Kingdom

  Bmj, Vol: 328 Page: 524; author reply 524 February 2004
  K. P. Prime; E. A. Jungmann; S. G. Edwards

  [Preview] [Read]

• 18.   Dental erosion -- changing prevalence? A review of British National childrens' surveys

  The aim of this study was to examine the prevalence of dental erosion, over time, by a review of the data from the published national dental surveys of young people in the United Kingdom

  

  Abstract:

  OBJECTIVES: To investigate the change in the prevalence of dental erosion, over time, by a review of the data from the published national dental surveys of young people in the UK. A subsidiary objective was to investigate the relationship between erosion and possible associated risk factors. DESIGN: The review was based on cross-sectional prevalence studies incorporating a clinical more...

  International Classification:

  Dental

  Categories:

  dental erosion

  Geography:

  the United Kingdom

  Int J Paediatr Dent, Vol: 13 Page: 98-105 March 2003
  J. H. Nunn; P. H. Gordon; A. J. Morris; C. M. Pine; A. Walker

  [Preview] [Read]

• 19.   Dietary folate and the prevalence of neural tube defects in the British Isles: the past two decades

  The aim of this study was to examine the changes in folate consumption and the prevalence of neural tube defects in the British and Irish populations during the past two decades

  

  Abstract:

  OBJECTIVES: To measure the changes in folate consumption and the prevalence of neural tube defects in the British and Irish populations during the past two decades. DESIGN: Ecological study. MAIN OUTCOME MEASURES: Average daily dietary folate consumption for Britain for the period 1980-1996 was estimated from the National Food Survey. Annual neural tube defect prevalences for the same more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - neural tube defects - condiction

  Categories:

  folate consumption; neural tube defects

  Geography:

  Republic of Ireland and the United Kingdom

  Bjog, Vol: 107 Page: 885-9 July 2000
  M. Murphy; D. Whiteman; D. Stone; B. Botting; C. Schorah; J. Wild

  [Preview] [Read]

• 20.   Differences in risk factors for partial and no immunisation in the first year of life: prospective cohort study

  The aim of the study was to compare demographic, social, maternal, and infant related factors associated with partial immunisation and no immunisation in the first year of life in the United Kingdom.

  

  Abstract:

  OBJECTIVE: To compare demographic, social, maternal, and infant related factors associated with partial immunisation and no immunisation in the first year of life in the United Kingdom. DESIGN: Prospective cohort study. SETTING: Sample of electoral wards in England, Wales, Scotland, and Northern Ireland, stratified by measures of ethnic composition and social disadvantage. PARTICIPANTS: more...

  International Classification:

  Vaccination

  Categories:

  immunisation

  Geography:

  the United Kingdom

  Bmj, Vol: 332 Page: 1312-3 June 2006
  L. Samad; A. R. Tate; C. Dezateux; C. Peckham; N. Butler; H. Bedford

  [Preview] [Read]

• 21.   Do early infant feeding practices vary by maternal ethnic group?

  The aim of this study was to examine United Kingdom country and ethnic variations in infant feeding practices

  

  Abstract:

  OBJECTIVE: To examine UK country and ethnic variations in infant feeding practices. DESIGN: Cohort study. SETTING: Infants enrolled in the Millennium Cohort Study, born between September 2000 and January 2002. SUBJECTS: A total of 18 150 natural mothers (11 286 (8207 white) living in England) of singleton infants. OUTCOME MEASURES: Breast-feeding initiation, breast-feeding more...

  International Classification:

  Other - infant feeding

  Categories:

  infant feeding practices

  Geography:

  the United Kingdom

  Public Health Nutr, Vol: 10 Page: 957-64 September 2007
  L. J. Griffiths; A. R. Tate; C. Dezateux

  [Preview] [Read]

• 22.   EPICure: facts and figures: why preterm labour should be treated

  The aim of this study was to was to determine both short- and long-term outcomes of extremely preterm birth data were collected for all births before 26 completed weeks of gestation

  

  Abstract:

  The principal objective of the EPICure studies was to determine both short- and long-term outcomes of extremely preterm birth. Data were collected for all births before 26 completed weeks of gestation in the UK and Republic of Ireland for 10 months in 1995. Of 811 infants admitted to neonatal units, 314 (39%) survived. Of these, 283 (92%) were assessed at 2.5 years and 241 (78%) at 6 more...

  International Classification:

  Premature - births

  Categories:

  outcomes of extremely preterm birth

  Geography:

  Republic of Ireland and the United Kingdom

  Bjog, Vol: 113 Suppl 3 Page: 10-2 December 2006
  K. Costeloe

  [Preview] [Read]

• 23.   Epidemiology of traumatic brain injury in children receiving intensive care in the UK

  The aim of this study was to examine the epidemiology of children with traumatic brain injury admitted to paediatric intensive care units in the United Kingdom

  

  Abstract:

  AIMS: To describe the epidemiology of children with traumatic brain injury (TBI) admitted to paediatric intensive care units (PICUs) in the UK. METHODS: Prospective collection of clinical and demographic information from paediatric and adult intensive care units in the UK and Eire between February 2001 and August 2003. RESULTS: The UK prevalence rate for children (0-14 years) admitted more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - injury

  Categories:

  traumatic brain injury

  Geography:

  Republic of Ireland and the United Kingdom

  Arch Dis Child, Vol: 90 Page: 1182-7 November 2005
  R. C. Parslow; K. P. Morris; R. C. Tasker; R. J. Forsyth; C. A. Hawley

  [Preview] [Read]

• 24.   Fertility assumptions for the 2002-based national population projections

  The aim of this study was to examine national population projections with regard to levels of fertility

  

  Abstract:

  One of the key components of national population projections is the assumed level of fertility, which determines the number of future births in the projections. Assumptions are made in terms of the average number of children women will have over their lifetime. For the 2002-based projections this average is assumed to ultimately be 1.75 for England and for Wales, 1.60 for Scotland, and more...

  International Classification:

  Other - fertility

  Categories:

  levels of fertility

  Geography:

  the United Kingdom

  Popul Trends, 2003 Winter
  S. Smallwood

  [Preview] [Read]

• 25.   Government initiatives to tackle the obesity epidemic

  This article highlights the prevalence of obesity in the United Kingdom and the associated health costs.

  

  Abstract:

  This article highlights the prevalence of obesity in the UK and the associated health costs. It discusses the attempts the government is making to halt the growth of the 'obesogenic' society and summarises practical tips and interventions of use when advising individuals on obesity issues. more...

  Geography:

  Northern Ireland

  Nurs Times, Vol: 101 Page: 23-4 2005 Sep 27-Oct 3
  K. Fisher

  [Preview] [Read]

• 26.   Group B streptococcal disease in UK and Irish infants younger than 90 days

  The aim of this study was to identified cases of invasive group B streptococcal disease in infants younger than 90 days through surveillance involving paediatricians, microbiologists, and parents

  

  Abstract:

  The incidence, morbidity, and mortality of group B streptococcal disease in the UK and Republic of Ireland are largely unknown. Between Feb 1, 2000, and Feb 28, 2001, we identified cases of invasive group B streptococcal disease in infants younger than 90 days through surveillance involving paediatricians, microbiologists, and parents. 568 cases were identified, equivalent to a total more...

  International Classification:

  Bacterium - Group B Strep

  Categories:

  Group B Strep

  Geography:

  Republic of Ireland and the United Kingdom

  Lancet, Vol: 363 Page: 292-4 January 2004
  P. T. Heath; G. Balfour; A. M. Weisner; A. Efstratiou; T. L. Lamagni; H. Tighe; L. A. O'Connell; M. Cafferkey; N. Q. Verlander; A. Nicoll; A. C. McCartney

  [Preview] [Read]

• 27.   Higher incidence of SIDS at weekends, especially in younger infants

  The aim of this study was to examine the magnitude of "weekends on deaths" in British data in relation to the "back to sleep" campaign.

  

  Abstract:

  BACKGROUND: An increased incidence of sudden infant death syndrome (SIDS) at weekends has been previously noted, although it has not been found in all studies. Where a weekend effect has been found it is most prominent on Sundays. AIM: To identify the magnitude of this effect in British data before and after the fall in prevalence associated with the "back to sleep" campaign. more...

  International Classification:

  Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified- Ill-defined and unknown causes of mortality - Sudden infant death syndrome

  Categories:

  sudden infant death syndrome

  Geography:

  the United Kingdom

  Arch Dis Child, Vol: 89 Page: 670-2 July 2004
  J. A. Mooney; P. J. Helms; I. T. Jolliffe

  [Preview] [Read]

• 28.   Human herpesviruses-6 and -7 each cause significant neurological morbidity in Britain and Ireland

  The aim of this study was to examine the extent of Human herpesvirus-6 and -7 infections in causing cause febrile illness in young children

  

  Abstract:

  BACKGROUND: Primary human herpesvirus-6 and -7 (HHV-6/-7) infections cause febrile illness sometimes complicated by convulsions and rarely encephalopathy. AIMS: To explore the extent of such HHV-6 and -7 induced disease in young children. METHODS: In a three year prospective study in Britain and Ireland, 205 children (2-35 months old) hospitalised with suspected encephalitis and/or more...

  International Classification:

  International committee on Taxonomy of Viruses - herpesvirus

  Categories:

  herpesvirus-6 and -7 infections; febrile illness

  Geography:

  Republic of Ireland and the United Kingdom

  Arch Dis Child, Vol: 90 Page: 619-23 June 2005
  K. N. Ward; N. J. Andrews; C. M. Verity; E. Miller; E. M. Ross

  [Preview] [Read]

• 29.   Identification of suspected fatal adverse drug reactions by paediatricians: a UK surveillance study

  The aim of this study was to examine the number of adverse drug reactions in children in the United Kingdom and Ireland

  

  Abstract:

  This British Paediatric Surveillance Unit (BPSU) study on adverse drug reactions (ADRs) in children was initiated because of concern that there might be under-reporting of serious ADRs in children using the yellow card scheme. We aimed to quantify the frequency of fatal ADRs in children under the age of 16 years in the United Kingdom and Ireland. The surveillance period ran for 13 more...

  International Classification:

  Drugs, pharmacological treatment - adverse reactions

  Categories:

  adverse drug reactions

  Geography:

  Republic of Ireland

  Arch Dis Child, Vol: 93 Page: 609-11 July 2008
  K. Cheng; S. Masters; T. Stephenson; R. Cooke; R. Ferner; M. Ashworth; A. J. Nunn

  [Preview] [Read]

• 30.   Idiopathic interstitial pneumonitis in children: a national survey in the United Kingdom and Ireland

  The aim of this study was to examine idiopathic interstitial pneumonitis in children

  

  Abstract:

  Interstitial lung disease (ILD) of unknown etiology in immunocompetent patients is rare in children. A national survey was carried out in the United Kingdom and Ireland over a 3-year period in order to identify prevalence, age distribution, histopathology, natural history of the illness, and response to current treatment.Forty-six cases were identified, including 29 males and 17 more...

  International Classification:

  Diseases of the respiratory system - pneumonitis

  Categories:

  Idiopathic interstitial pneumonitis

  Geography:

  Republic of Ireland and the United Kingdom

  Pediatr Pulmonol, Vol: 34 Page: 23-9 July 2002
  R. Dinwiddie; N. Sharief; O. Crawford

  [Preview] [Read]

• 31.   Impact of exclusion criteria on case mix, outcome, and length of stay for the severity of disease scoring methods in common use in critical care

  This study examined the exclusion criteria for the major severity of disease scoring methods in critical care and to investigate the impact of the exclusion criteria on the case mix, outcomes and length of stay for admissions to intensive care units

  

  Abstract:

  OBJECTIVE: To identify the exclusion criteria for the major severity of disease scoring methods in critical care and to investigate the impact of the exclusion criteria on the case mix, outcomes and length of stay for admissions to intensive care units (ICUs) in England, Wales and Northern Ireland. DESIGN: Cohort study-analysis of prospectively collected data. SETTING: 127 adult, more...

  International Classification:

  Diagnostic tool (inclusion/exclusion criteria) -major severity of disease

  Categories:

  inclusion/exclusion criteria; critical care

  Geography:

  the United Kingdom

  J Crit Care, Vol: 19 Page: 67-74 June 2004
  H. Wunsch; A. R. Brady; K. Rowan

  [Preview] [Read]

• 32.   Incidence of systemic lupus erythematosus in the United Kingdom, 1990-1999

  The aim of this study was to examine the annual incidence of systemic lupus erythematosus (SLE) over a 10-year period in the UK

  

  Abstract:

  OBJECTIVE: To estimate the annual incidence of systemic lupus erythematosus (SLE) over a 10-year period in the UK, and to examine age-, sex-, and region-specific rates. METHODS: The study was based on the UK General Practice Research Database (GPRD), which covers approximately 5% of the UK population. We estimated SLE incidence rates, during the period 1990-1999, among persons more...

  International Classification:

  Diseases of the skin and subcutaneous tissue - Other disorders of the skin and subcutaneous tissue - systemic lupus erythematosus

  Categories:

  systemic lupus erythematosus

  Geography:

  the United Kingdom

  Arthritis Rheum, Vol: 57 Page: 612-8 May 2007
  E. C. Somers; S. L. Thomas; L. Smeeth; W. M. Schoonen; A. J. Hall

  [Preview] [Read]

• 33.   Increasing numbers at a specialist coeliac clinic: contribution of serological testing in primary care

  This study examined new coeliac patients seen over a 9-year period to determine how the availability of serology, particularly to primary care physicians, has changed rates and sources of diagnosis

  

  Abstract:

  BACKGROUND: Serological testing, using IgA class endomysial and tissue transglutaminase antibodies has high sensitivity and specificity for coeliac disease and allows case finding by clinicians other than gastroenterologists. We reviewed new coeliac patients seen over a 9-year period to determine how the availability of serology, particularly to primary care physicians, has changed more...

  International Classification:

  Diseases of the digestive system - Other diseases of the digestive system - coeliac disease

  Categories:

  coeliac disease

  Geography:

  Northern Ireland

  Dig Liver Dis, Vol: 37 Page: 928-33 December 2005
  W. Dickey; S. A. McMillan

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• 34.   Infant and toddler diabetes

  This article discusses infant and toddler diabetes

  

  Geography:

  Republic of Ireland

  Arch Dis Child, Vol: 92 Page: 716-9 August 2007
  D. Cody

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• 35.   Intravenous postoperative fluid prescriptions for children: a survey of practice

  This study aimed to explore the rates and types of intravenous fluids being prescribed postoperatively for children in the United Kingdom

  

  Abstract:

  BACKGROUND: Postoperative deaths and neurological injury have resulted from hyponatraemia associated with the use of hypotonic saline solutions following surgery. We aimed to determine the rates and types of intravenous fluids being prescribed postoperatively for children in the UK. METHODS: A questionnaire was sent to members of the British Association of Paediatric Surgeons (BAPS) and more...

  International Classification:

  Practice/knowledge - intravenous fluids

  Categories:

  intravenous fluids;

  Geography:

  Republic of Ireland and the United Kingdom

  BMC Surg, Vol: 8 Page: 10 2008
  P. Davies; T. Hall; T. Ali; K. Lakhoo

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• 36.   Invasive fungal infection in very low birthweight infants: national prospective surveillance study

  The aim of this study was to examine the epidemiology of invasive fungal infection in very low birthweight (VLBW: <1500 g) infants in the United Kingdom

  

  Abstract:

  OBJECTIVE: To describe the epidemiology of invasive fungal infection in very low birthweight (VLBW: <1500 g) infants in the United Kingdom. DESIGN: National prospective surveillance study between February 2003 and February 2004 using the British Paediatric Surveillance Unit reporting system reconciled with cases identified through routine laboratory reporting to the Health Protection more...

  International Classification:

  Premature - infants

  Categories:

  invasive fungal infection; very low birthweight

  Geography:

  the United Kingdom

  Arch Dis Child Fetal Neonatal Ed, Vol: 91 Page: F188-92 May 2006
  L. Clerihew; T. L. Lamagni; P. Brocklehurst; W. McGuire

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• 37.   Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006

  The aim of this study was to describe the impact of different strategies to prevent mother-to-child transmission of HIV at a population level

  

  Abstract:

  AIM: In the United Kingdom (UK) and Ireland, avoidance of breastfeeding and alternative combinations of antiretroviral therapy regimen and mode of delivery are recommended according to maternal clinical status. The aim of this analysis was to explore the impact of different strategies to prevent mother-to-child transmission at a population level. DESIGN: Comprehensive national more...

  International Classification:

  Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV

  Categories:

  HIV

  Geography:

  Republic of Ireland and the United Kingdom

  Aids, Vol: 22 Page: 973-81 May 2008
  C. L. Townsend; M. Cortina-Borja; C. S. Peckham; A. de Ruiter; H. Lyall; P. A. Tookey

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• 38.   Morbidity, mortality, and response to treatment by children in the United Kingdom and Ireland with perinatally acquired HIV infection during 1996-2006: planning for teenage and adult care

  The aim of this study was to examine temporal changes in the morbidity and mortality persons with perinatally acquired HIV infection, many of whom are now adolescents.

  

  Abstract:

  BACKGROUND: Recent evidence suggests that decreases in morbidity and mortality in cohorts of adults infected with human immunodeficiency virus (HIV) are showing signs of reversal. We describe changes over time in these characteristics and in the response to treatment among children in the United Kingdom and Ireland with perinatally acquired HIV infection, many of whom are now more...

  International Classification:

  Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV

  Categories:

  perinatally acquired HIV infection

  Geography:

  Republic of Ireland and the United Kingdom

  Clin Infect Dis, Vol: 45 Page: 918-24 October 2007
  A. Judd; K. Doerholt; P. A. Tookey; M. Sharland; A. Riordan; E. Menson; V. Novelli; E. G. Lyall; J. Masters; G. Tudor-Williams; T. Duong; D. M. Gibb

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• 39.   Motor and executive function at 6 years of age after extremely preterm birth

  The aim of this study was to examine the hypothesize that neuromotor and executive-function deficits may independently contribute to school failure in extreme premature birth and motor and executive function at 6 years of age

  

  Abstract:

  BACKGROUND: Studies of very preterm infants have demonstrated impairments in multiple neurocognitive domains. We hypothesized that neuromotor and executive-function deficits may independently contribute to school failure. METHODS: We studied children who were born at < or = 25 completed weeks' gestation in the United Kingdom and Ireland in 1995 at early school age. Children underwent more...

  International Classification:

  Premature - births

  Categories:

  school failure

  Geography:

  Republic of Ireland and the United Kingdom

  Pediatrics, Vol: 120 Page: 793-804 October 2007
  N. Marlow; E. M. Hennessy; M. A. Bracewell; D. Wolke

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• 40.   Neonatal death rate continues to fall in England, Wales, and Northern Ireland

  This article discusses the neonatal death rate

  

  Geography:

  the United Kingdom

  Bmj, Vol: 336 Page: 1095 May 2008
  S. Mayor

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• 41.   Neurologic and developmental disability after extremely preterm birth. EPICure Study Group

  The aim of this study was to examine neurologic and developmental disability in children who were born at 25 or fewer completed weeks of gestation in the United Kingdom and Ireland

  

  Abstract:

  BACKGROUND AND METHODS: Small studies show that many children born as extremely preterm infants have neurologic and developmental disabilities. We evaluated all children who were born at 25 or fewer completed weeks of gestation in the United Kingdom and Ireland from March through December 1995 at the time when they reached a median age of 30 months. Each child underwent a formal more...

  International Classification:

  Premature - children

  Categories:

  Neurologic and developmental disability; preterm births

  Geography:

  Republic of Ireland and the United Kingdom

  N Engl J Med, Vol: 343 Page: 378-84 August 2000
  N. S. Wood; N. Marlow; K. Costeloe; A. T. Gibson; A. R. Wilkinson

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• 42.   New adult patients starting renal replacement therapy in the UK in 2005 (chapter 3)

  The aim of this study was to examine the acceptance rate for renal replacement therapy and characteristics of the target population

  

  Abstract:

  In 2005, the acceptance rate for renal replacement therapy (RRT) in adults in the UK was 108 per million population (pmp). This was derived from complete data for adults in the UK, as data were obtained separately from the five English renal units not currently returning to the Registry. In addition, 87 children started RRT (see Chapter 13) giving a total incidence of 110 pmp. From 2001 more...

  International Classification:

  Procedure - renal replacement therapy

  Categories:

  renal replacement therapy

  Geography:

  the United Kingdom

  Nephrol Dial Transplant, Vol: 22 Suppl 7 Page: vii11-29 August 2007
  K. Farrington; R. Rao; J. Gilg; D. Ansell; T. Feest

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• 43.   Non-type b Haemophilus influenzae disease: clinical and epidemiologic characteristics in the Haemophilus influenzae type b vaccine era

  The aim of this study was to describe the clinical and epidemiologic features of non-b Hi disease

  

  Abstract:

  BACKGROUND: As a result of the decline in Haemophilus influenzae type b (Hib) disease caused by the widespread use of conjugate vaccines, non-type b H. influenzae will become a more important cause of H. influenzae (Hi) disease. Characterization of the clinical and epidemiologic features of non-b Hi disease is needed in the Hib vaccine era. METHODS: A prospective active surveillance more...

  International Classification:

  Other - non-b Haemophilus influenzae disease

  Categories:

  non-b Hi disease

  Geography:

  Republic of Ireland and the United Kingdom

  Pediatr Infect Dis J, Vol: 20 Page: 300-5 March 2001
  P. T. Heath; R. Booy; H. J. Azzopardi; M. P. Slack; J. Fogarty; A. C. Moloney; M. E. Ramsay; E. R. Moxon

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• 44.   Pervasive behavior problems at 6 years of age in a total-population sample of children born at

  The aim of this study was to test whether extremely preterm children have more pervasive behaviour problems than classroom peers, by using parent and teacher consensus reports

  

  Abstract:

  OBJECTIVE: The goal was to test whether extremely preterm children have more pervasive behavior problems than classroom peers, by using parent and teacher consensus reports. Is there an excess number of extremely preterm boys with behavior problems? METHODS: A total-population study of all extremely preterm children in the United Kingdom and Ireland was performed. All children born at more...

  International Classification:

  Premature - children

  Categories:

  behavior problems; -preterm children;

  Geography:

  Republic of Ireland

  Pediatrics, Vol: 122 Page: 562-73 September 2008
  M. Samara; N. Marlow; D. Wolke

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• 45.   Pneumocystis carinii pneumonia and cytomegalovirus infection in children with vertically acquired HIV infection

  The aim of this study was to examine the prevalence, clinical characteristics, management and changes in survival over time of vertically HIV-infected infants developing PCP and/or CMV infection

  

  Abstract:

  OBJECTIVES: The outcome of Pneumocystis carinii pneumonia (PCP) in HIV-infected infants is poor, and the role of cytomegalovirus (CMV) co-infection in the course and outcome of PCP is unclear. This study describes the prevalence, clinical characteristics, management and changes in survival over time of vertically HIV-infected infants developing PCP and/or CMV infection. METHODS: Data on more...

  International Classification:

  Certain infectious and parasitic diseases - Human immunodeficiency virus [HIV] disease - HIV

  Categories:

  HIV-infected

  Geography:

  Republic of Ireland and the United Kingdom

  Aids, Vol: 15 Page: 335-9 February 2001
  A. J. Williams; T. Duong; L. M. McNally; P. A. Tookey; J. Masters; R. Miller; E. G. Lyall; D. M. Gibb

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• 46.   Prediction of raised intracranial pressure complicating severe traumatic brain injury in children: implications for trial design

  This study aimed to describe current patterns of management of raised intracranial pressure in traumatic brain injury relevant to clinician buy-in to possible randomized controlled trials of treatments of raised ICP

  

  Abstract:

  OBJECTIVES: To describe current patterns of management of raised intracranial pressure (ICP) in traumatic brain injury relevant to clinician buy-in to possible randomized controlled trials of treatments of raised ICP. To examine the feasibility of early identification of children at sufficient risk of developing raised ICP to permit a uniform approach between centers to the initiation more...

  International Classification:

  Injury, poisoning and certain other consequences of external causes - traumatic brain injury

  Categories:

  raised intracranial pressure; traumatic brain injury

  Geography:

  Republic of Ireland and the United Kingdom

  Pediatr Crit Care Med, Vol: 9 Page: 8-14 January 2008
  R. J. Forsyth; R. C. Parslow; R. C. Tasker; C. A. Hawley; K. P. Morris

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• 47.   Prevalence of abnormal urinary albumin excretion in adolescents and children with insulin dependent diabetes: the MIDAC study. Microalbinuria in Diabetic Adolescents and Children (MIDAC) research group

  The aim of this study was to examine the prevalence of abnormal urinary albumin excretion in adolescents and children with insulin dependent diabetes: the MIDAC study. Microalbinuria in Diabetic Adolescents and Children (MIDAC) research group

  

  Abstract:

  OBJECTIVE: To examine the prevalence of microalbuminuria, defined as an albumin to creatinine ratio (UAC) equal to or greater than 2 mg/mmol in at least two of three early morning urine samples, in adolescents and children with insulin dependent diabetes mellitus. DESIGN: Centrally coordinated, cross sectional, multicentre study in paediatric diabetes outpatient clinics in the United more...

  International Classification:

  Endocrine, nutritional and metabolic diseases - Diabetes mellitus - insulin dependent diabetes

  Categories:

  abnormal urinary albumin excretion; insulin dependent diabetes

  Geography:

  Republic of Ireland and the United Kingdom

  Arch Dis Child, Vol: 83 Page: 239-43 September 2000
  T. H. Moore; J. P. Shield

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• 48.   Prospective survey of childhood inflammatory bowel disease in the British Isles

  The aim of this study was to examine the incidence of childhood inflammatory bowel disease in the British Isles

  

  Abstract:

  The incidence of inflammatory bowel disease in children in western countries may be rising. Since there is no prospective national data on the incidence of inflammatory bowel disease in the UK and Republic of Ireland (ROI), we undertook a prospective survey to determine this incidence. The incidence during 1998 and 1999 was 5.2/100,000 per year in children aged younger than 16 years. more...

  International Classification:

  Other - Inflammatory bowel disease - non specific

  Categories:

  inflammatory bowel disease

  Geography:

  Republic of Ireland and the United Kingdom

  Lancet, Vol: 357 Page: 1093-4 April 2001
  A. Sawczenko; B. K. Sandhu; R. F. Logan; H. Jenkins; C. J. Taylor; S. Mian; R. Lynn

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• 49.   Renal transplantation in the UK and Republic of Ireland

  The aim of this study was to examine 5-year renal transplant survival in the United Kingdom

  

  Abstract:

  RENAL TRANSPLANT OUTCOME: Analysis of 5-year transplant survival in the UK showed a number of significant factors influencing outcome of adult cadaveric renal transplantation. Data from 5,963 first grafts and 1,078 regrafts carried out between 1990-1997 showed year of graft, recipient age and diabetes, donor age, kidney exchange between centres and HLA matching to influence 5-year more...

  International Classification:

  Organ transplants

  Categories:

  transplant survival

  Geography:

  Republic of Ireland and the United Kingdom

  Clin Transpl, 2000
  R. J. Johnson; M. A. Belger; J. D. Briggs; S. V. Fuggle; P. J. Morris

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• 50.   Reye's syndrome: the case for a causal link with aspirin

  This article discusses the link between the devastating encephalopathy Reye's syndrome and ingestion of aspirin during the febrile prodrome

  

  Abstract:

  Reye's syndrome is a serious, acute encephalopathy that has been linked with aspirin (acetylsalicylic acid) use in children and teenagers <18 years of age. Although others may disagree, it is my belief that any objective analysis of published material in the last 20 years must conclude that there is a close link between the devastating encephalopathy Reye's syndrome and ingestion of more...

  Geography:

  Northern Ireland

  Drug Saf, Vol: 29 Page: 1111-21 2006
  J. F. Glasgow

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• 51.   Rising incidence of type 2 diabetes in children in the U.K

  The aim of this study was to examine the incidence of type 2 diabetes in children <17 years of age and to investigate the relationship of diabetes with increasing childhood obesity in the U.K. and the Republic of Ireland (ROI)

  

  Abstract:

  OBJECTIVE: To estimate the incidence of type 2 diabetes in children <17 years of age and to investigate the relationship of diabetes with increasing childhood obesity in the U.K. and the Republic of Ireland (ROI). RESEARCH DESIGN AND METHODS: Active monthly reporting of cases by consultant pediatricians occurred through the framework of the British Pediatric Surveillance Unit, with more...

  International Classification:

  Endocrine, nutritional and metabolic diseases - Diabetes mellitus - type 2 diabetes mellitus

  Categories:

  type 2 diabetes; type 2 diabetes; obesity

  Geography:

  Republic of Ireland and the United Kingdom

  Diabetes Care, Vol: 30 Page: 1097-101 May 2007
  L. Haines; K. C. Wan; R. Lynn; T. G. Barrett; J. P. Shield

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